ISRN biomedical engineering最新文献

Mathematical Methods in Biomedical Optics 生物医学光学中的数学方法

ISRN biomedical engineering Pub Date : 2013-12-30 DOI: 10.1155/2013/464293

M. Gabriela

引用次数: 6

Optical Measurement of Blood Oxygen Saturation of Dental Pulp 牙髓血氧饱和度的光学测量

ISRN biomedical engineering Pub Date : 2013-11-06 DOI: 10.1155/2013/502869

S. Kakino, Shinya Kushibiki, Azusa Yamada, Z. Miwa, Y. Takagi, Y. Matsuura

引用次数: 12

Slip Effects on Pulsatile Flow of Blood through a Stenosed Arterial Segment under Periodic Body Acceleration 在周期性身体加速下，滑移对狭窄动脉段血液脉动流动的影响

ISRN biomedical engineering Pub Date : 2013-08-18 DOI: 10.1155/2013/925876

A. Sinha, G. C. Shit, P. K. Kundu

{"title":"Slip Effects on Pulsatile Flow of Blood through a Stenosed Arterial Segment under Periodic Body Acceleration","authors":"A. Sinha, G. C. Shit, P. K. Kundu","doi":"10.1155/2013/925876","DOIUrl":"https://doi.org/10.1155/2013/925876","url":null,"abstract":"A theoretical investigation concerning the influence of externally imposed periodic body acceleration on the flow of blood through a time-dependent stenosed arterial segment by taking into account the slip velocity at the wall of the artery has been carried out. A mathematical model is developed by treating blood as a non-Newtonian fluid obeying the Casson fluid model. The pulsatile flow is analyzed by considering a periodic pressure \u0000gradient and the inertial effects as negligibly small. A suitable generalized geometry for time-dependent stenosis is taken into account. Perturbation method is used to solve the coupled implicit system of nonlinear differential equations that govern the flow of blood. Analytical expressions for the velocity profile, volumetric flow rate, and wall shear stress are obtained. A thorough quantitative analysis has been made through numerical computations \u0000of the variables involved in the analysis that are of special interest in this study. \u0000The computational results are presented graphically. The results for different values of the parameters involved in the problem under consideration presented here show that the flow is appreciably influenced by slip velocity in the presence of periodic body acceleration.","PeriodicalId":93456,"journal":{"name":"ISRN biomedical engineering","volume":"2013 1","pages":"1-10"},"PeriodicalIF":0.0,"publicationDate":"2013-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/925876","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64314758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 22

High-Fidelity Visualization of Large Medical Datasets on Commodity Hardware 商用硬件上大型医疗数据集的高保真可视化

ISRN biomedical engineering Pub Date : 2013-06-27 DOI: 10.1155/2013/892967

Luigi Gallo, Alessio Pierluigi Placitelli

引用次数: 3

Companding Realizations of the Nonlinear Energy Operator 非线性能量算子的扩展实现

ISRN biomedical engineering Pub Date : 2013-06-20 DOI: 10.1155/2013/750290

A. Demartinos, Chrysostomos Kasimis, C. Laoudias, C. Psychalinos

引用次数: 7

A New Approach to Detect Epileptic Seizures in Electroencephalograms Using Teager Energy 一种利用青少年能量检测脑电图癫痫发作的新方法

ISRN biomedical engineering Pub Date : 2013-06-19 DOI: 10.1155/2013/358108

C. Kamath

{"title":"A New Approach to Detect Epileptic Seizures in Electroencephalograms Using Teager Energy","authors":"C. Kamath","doi":"10.1155/2013/358108","DOIUrl":"https://doi.org/10.1155/2013/358108","url":null,"abstract":"A Teager energy (TE) based approach to discriminate electroencephalogram signals corresponding to nonseizure (eyes open, eyes closed, or interictal) and seizure (ictal) intervals is proposed. Though a good number of contributions have been made for seizure detection, the challenges of unbalanced data (nonseizure and seizure events) and system computational efficiency still remain a challenge. It is reported in the literature that the seizures are characterized by abnormal sudden discharges in the brain which get manifested in the EEG recordings by frequency changes and increased amplitudes. Teager energy (TE) is capable of tracking such rapid changes in frequency as well as amplitude in the time domain. An important finding of this study is that the mean TE quantifier is largely independent of the window length and exhibits relative consistency when used as a relative measure for comparison. We compared the diagnostic capability of TE quantifier with those of Higuchi’s fractal dimension and sample entropy in discriminating nonseizure and seizure states in the EEGs and found that TE outperforms the other two nonlinear quantifiers. The result shows that the application of this method compares favorably with conventional classification methods in terms of performance and is well suited for real-time automatic epileptic seizure detection.","PeriodicalId":93456,"journal":{"name":"ISRN biomedical engineering","volume":"2013 1","pages":"1-14"},"PeriodicalIF":0.0,"publicationDate":"2013-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/358108","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64409507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12

Ambulatory Monitoring of Physical Activity Based on Knee Flexion/Extension Measured by Inductive Sensor Technology 基于感应传感器技术测量膝关节屈伸的身体活动动态监测

ISRN biomedical engineering Pub Date : 2013-06-09 DOI: 10.1155/2013/908452

Bert Bonroy, K. Meijer, P. Dunias, K. Cuppens, R. Gransier, B. Vanrumste

{"title":"Ambulatory Monitoring of Physical Activity Based on Knee Flexion/Extension Measured by Inductive Sensor Technology","authors":"Bert Bonroy, K. Meijer, P. Dunias, K. Cuppens, R. Gransier, B. Vanrumste","doi":"10.1155/2013/908452","DOIUrl":"https://doi.org/10.1155/2013/908452","url":null,"abstract":"We developed a knee brace to measure the knee angle and implicitly the flexion/extension (f/e) of the knee joint during daily activities. The goal of this study is to classify and validate a limited set of physical activities on ten young healthy subjects based on knee f/e. Physical activities included in this study are walking, ascending and descending of stairs, and fast locomotion (such as jogging, running, and sprinting) at self-selected speeds. The knee brace includes 2 accelerometers for static measurements and calibration and an inductive sensor for dynamic measurements. As we focus on physical activities, the inductive sensor will provide the required information on knee f/e. In this study, the subjects traversed a predefined track which consisted of indoor paths, outdoor paths, and obstacles. The activity classification algorithm based on peak detection in the knee f/e angle resulted in a detection rate of 95.9% for walking, 90.3% for ascending stairs, 78.3% for descending stairs, and 82.2% for fast locomotion. We conclude that we developed a measurement device which allows long-term and ambulatory monitoring. Furthermore, it is possible to predict the aforementioned activities with an acceptable performance.","PeriodicalId":93456,"journal":{"name":"ISRN biomedical engineering","volume":"86 1","pages":"1-10"},"PeriodicalIF":0.0,"publicationDate":"2013-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/908452","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64307855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

Diffusion in Replica Healthy and Emphysematous Alveolar Models Using Computational Fluid Dynamics 利用计算流体动力学研究健康肺泡模型和肺气肿肺泡模型的扩散

ISRN biomedical engineering Pub Date : 2013-06-03 DOI: 10.1155/2013/919802

Edward M. Harding, E. Berg, R. Robinson

{"title":"Diffusion in Replica Healthy and Emphysematous Alveolar Models Using Computational Fluid Dynamics","authors":"Edward M. Harding, E. Berg, R. Robinson","doi":"10.1155/2013/919802","DOIUrl":"https://doi.org/10.1155/2013/919802","url":null,"abstract":"Deposition of nanosized particles in the pulmonary region has the potential of crossing the blood-gas barrier. Experimental in vivo studies have used micron-sized particles, and therefore nanoparticle deposition in the pulmonary region is not well understood. Furthermore, little attention has been paid to the emphysematous lungs, which have characteristics quite different from the healthy lung. Healthy and emphysematous replica acinus models were created from healthy and diseased human lung casts using three-dimensional reconstruction. Particle concentration and deposition were determined by solving the convective-diffusion equation numerically for steady and unsteady cases. Results showed decreased deposition efficiencies for emphysema compared to healthy lungs, consistent with the literature and attributed to significant airway remodeling in the diseased lung. Particle diffusion was found to be six times slower in emphysema compared to healthy model. The unsteady state simulation predicted deposition efficiencies of 96% in the healthy model for the 1 nm and 3 nm particles and 94% and 93% in the emphysema model for the 1 nm and 3 nm particles, respectively. Steady state was achieved in less than one second for both models. Comparisons between steady and unsteady predictions indicate that a steady-state simulation is reasonable for predicting particle transport under similar conditions.","PeriodicalId":93456,"journal":{"name":"ISRN biomedical engineering","volume":"2013 1","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2013-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/919802","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64312840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Extrahepatic 25-Hydroxylation of Vitamin D₃ in an Engineered Osteoblast Precursor Cell Line Exploring the Influence on Cellular Proliferation and Matrix Maturation during Bone Development. 维生素 D3 在工程成骨细胞前体细胞系中的肝外 25-羟化，探索其对骨骼发育过程中细胞增殖和基质成熟的影响。

ISRN biomedical engineering Pub Date : 2013-01-01 Epub Date: 2013-06-04 DOI: 10.1155/2013/956362

Shelley S Mason, Sean S Kohles, Shelley R Winn, Randy D Zelick

{"title":"Extrahepatic 25-Hydroxylation of Vitamin D3 in an Engineered Osteoblast Precursor Cell Line Exploring the Influence on Cellular Proliferation and Matrix Maturation during Bone Development.","authors":"Shelley S Mason, Sean S Kohles, Shelley R Winn, Randy D Zelick","doi":"10.1155/2013/956362","DOIUrl":"10.1155/2013/956362","url":null,"abstract":"Osteoblastic precursors experience distinct stages during differentiation and bone development, which include proliferation, extracellular matrix (ECM) maturation, and ECM mineralization. It is well known that vitamin D plays a large role in the regulation of bone mineralization and homeostasis via the endocrine system. The activation of vitamin D requires two sequential hydroxylation steps, first in the kidney and then in the liver, in order to carry out its role in calcium homeostasis. Recent research has demonstrated that human-derived mesenchymal stem cells (MSCs) and osteoblasts can metabolize the immediate vitamin D precursor 25-dihydroxyvitamin D3 (25OHD3) to the active steroid lα,25-dihydroxyvitamin D3 (1,25OH2D3) and elicit an osteogenic response. However, reports of extrahepatic metabolism of vitamin D3, the parental vitamin D precursor, have been limited. In this study, we investigated whether osteoblast precursors have the capacity to convert vitamin D3 to 1,25OH2D3 and examined the potential of vitamin D3 to induce 1,25OH2D3 associated biological activities in osteoblast precursors. It was demonstrated that the engineered osteoblast precursor derived from human marrow (OPC1) is capable of metabolizing vitamin D3 to 1,25OH2D3 in a dose-dependent manner. It was also demonstrated that administration of vitamin D3 leads to the increase in alkaline phosphatase (ALP) activity associated with osteoblast ECM maturation and calcium deposits and a decrease in cellular proliferation in both osteoblast precursor cell lines 0PC1 andOMC3T3-E1. These findings provide a two-dimensional culture foundation for future three-dimensional engineered tissue studies using the OPC1 cell line.","PeriodicalId":93456,"journal":{"name":"ISRN biomedical engineering","volume":"2013 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667671/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39815921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0