{"title":"Current state of knowledge on the excretion of mRNA and spike produced by anti-COVID-19 mRNA vaccines; possibility of contamination of the entourage of those vaccinated by these products","authors":"H. Banoun","doi":"10.53388/idr20221125022","DOIUrl":"https://doi.org/10.53388/idr20221125022","url":null,"abstract":"The massive COVID-19 vaccination campaign is the first time that mRNA vaccines have been used on a global scale. The mRNA vaccines correspond exactly to the definition of gene therapy of the American and European regulatory agencies. The regulations require excretion studies of these drugs and their products (the translated proteins). These studies have not been done for mRNA vaccines (nor for adenovirus vaccines). There are numerous reports of symptoms and pathologies identical to the adverse effects of mRNA vaccines in unvaccinated persons in contact with freshly vaccinated persons. It is therefore important to review the state of knowledge on the possible excretion of vaccine nanoparticles as well as mRNA and its product, the spike protein. Vaccine mRNA-carrying lipid nanoparticles spread after injection throughout the body according to available animal studies and vaccine mRNA (naked or in nanoparticles or in natural exosomes) is found in the bloodstream as well as vaccine spike in free form or encapsulated in exosomes (shown in human studies). Lipid nanoparticles (or their natural equivalent, exosomes or extracellular vesicles (EVs)) have been shown to be able to be excreted through body fluids (sweat, sputum, breast milk) and to pass the transplacental barrier. These EVs are also able to penetrate by inhalation and through the skin (healthy or injured) as well as orally through breast milk (and why not during sexual intercourse through semen, as this has not been studied). It is urgent to enforce the legislation on gene therapy that applies to mRNA vaccines and to carry out studies on this subject while the generalization of mRNA vaccines is being considered.","PeriodicalId":93445,"journal":{"name":"Infectious diseases research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70810551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Singh, H. Agri, Dhayananth Balusamy, V. Jayakumar
{"title":"Bacterial profile and comparative antimicrobial efficacy of fresh urine of cows, buffaloes and humans","authors":"B. Singh, H. Agri, Dhayananth Balusamy, V. Jayakumar","doi":"10.53388/idr20221125023","DOIUrl":"https://doi.org/10.53388/idr20221125023","url":null,"abstract":"","PeriodicalId":93445,"journal":{"name":"Infectious diseases research","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70810575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yusuf Mehkri, Patrick Felisma, Eric Panther, Brandon Lucke-Wold
{"title":"Osteomyelitis of the spine: treatments and future directions.","authors":"Yusuf Mehkri, Patrick Felisma, Eric Panther, Brandon Lucke-Wold","doi":"10.53388/idr20220117003","DOIUrl":"10.53388/idr20220117003","url":null,"abstract":"<p><strong>Background: </strong>Osteomyelitis of the spine is a serious condition that has been increasing with the intravenous drug pandemic and aging population. Multiple different organisms can cause osteomyelitis and mainstay of treatment is early recognition and antibiotics. The course can sometimes be indolent leading to delayed presentations. Once suspected, comprehensive workup and initiation of management should be employed. In rare circumstances, surgical evacuation or deformity correction is indicated. Continued antibiotic treatment should be considered post-operatively.</p><p><strong>Methods: </strong>Emerging treatment solutions are being developed to help target osteomyelitis in a more effective manner. In this review, we highlight the epidemiology and pathophysiology of spinal osteomyelitis. We overview the diagnostic workup and treatment options. Finally, we present new options that are currently being investigated and are on the near horizon.</p><p><strong>Conclusion: </strong>This review offers a user friendly resource for clinicians and researchers regarding osteomyelitis of the spine and will serve as a catalyst for further discovery.</p>","PeriodicalId":93445,"journal":{"name":"Infectious diseases research","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39959912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Malondialdehyde and superoxide dismutase levels of dogs with complex dermatitis after trigona honey therapy","authors":"N. Luh, I. Nyoman, P. Devi","doi":"10.53388/idr20220525012","DOIUrl":"https://doi.org/10.53388/idr20220525012","url":null,"abstract":"","PeriodicalId":93445,"journal":{"name":"Infectious diseases research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70809982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hazar Hamza, Djamila Mokrani, Billal Nia, Abdelkader Touil
{"title":"Use of traditional medicine in Algeria as an alternative treatment against COVID-19 in the context of modern medicine: a survey-based study","authors":"Hazar Hamza, Djamila Mokrani, Billal Nia, Abdelkader Touil","doi":"10.53388/idr20220525007","DOIUrl":"https://doi.org/10.53388/idr20220525007","url":null,"abstract":"","PeriodicalId":93445,"journal":{"name":"Infectious diseases research","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70810157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
XiXing Fang, Jiaxin Dong, Ziqi Wu, HaiChi Yang, H. Cui, Yilin Liu
{"title":"Analysis of knowledge graph based on CiteSpace research on the treatment of pediatric pneumonia with traditional Chinese medicine","authors":"XiXing Fang, Jiaxin Dong, Ziqi Wu, HaiChi Yang, H. Cui, Yilin Liu","doi":"10.53388/idr20220825016","DOIUrl":"https://doi.org/10.53388/idr20220825016","url":null,"abstract":"","PeriodicalId":93445,"journal":{"name":"Infectious diseases research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70810277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}