{"title":"The Protective Effect of Omega 3 and Vitamin D in Preventing Damage Occurring in Central Nervous System of Neonatal Rats Exposed to Cigarette Smoke in Intrauterine Period","authors":"Hayri Gözlükgiller","doi":"10.24966/ncp-878x/100085","DOIUrl":"https://doi.org/10.24966/ncp-878x/100085","url":null,"abstract":"In our study, the toxic effects of cigarette smoke exposure on central nervous system and the protective role of Omega 3 and Vitamin D against these toxic effects were investigated at biochemical and histological level.","PeriodicalId":93307,"journal":{"name":"Journal of clinical pediatrics and neonatology","volume":"110 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75995985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevalence of Sleep Bruxism in Brazilian children and association with type of delivery, breastfeeding period and oral habits with follow-up in 3 decades","authors":"Renato Barcellos Rédua","doi":"10.24966/ncp-878x/100086","DOIUrl":"https://doi.org/10.24966/ncp-878x/100086","url":null,"abstract":"To verify the prevalence of Sleep Bruxism (SB) in children in the last 3 decades and to verify the possible association of this condition with type of delivery, breastfeeding period, oral habits and gender","PeriodicalId":93307,"journal":{"name":"Journal of clinical pediatrics and neonatology","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87329849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Seroprevalence and Co-infection of Hepatitis A and Hepatitis E Viruses in children - A hospital-based study in Bangladesh","authors":"Bodhrun Naher","doi":"10.24966/ncp-878x/100080","DOIUrl":"https://doi.org/10.24966/ncp-878x/100080","url":null,"abstract":"Viral hepatitis is a serious health problem globally and in endemic countries like Bangladesh. Viral hepatitis may present as mono-infection or co-infection caused by Hepatitis A Virus (HAV), hepatitis B virus, hepatitis C virus, hepatitis D virus, and Hepatitis E Virus (HEV)","PeriodicalId":93307,"journal":{"name":"Journal of clinical pediatrics and neonatology","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90305738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Fonseca, Centro Hospitalar Universitário De São João
{"title":"Valorization of Erythrocyte Indices in the Neonatal Period - A Pilot Study","authors":"S. Fonseca, Centro Hospitalar Universitário De São João","doi":"10.24966/ncp-878x/100083","DOIUrl":"https://doi.org/10.24966/ncp-878x/100083","url":null,"abstract":"Abnormal red blood cell indices are frequently missed among newborns that perform blood tests for any clinical reason.","PeriodicalId":93307,"journal":{"name":"Journal of clinical pediatrics and neonatology","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84456557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Benefits of Using of a Low-Calorie Whey Peptide Enteral Formula in Children with Gastrointestinal Impairment, Complex Condition and Having Lower Energy Needs - A Series of Clinical Case Reports","authors":"E. Wright","doi":"10.24966/ncp-878x/100084","DOIUrl":"https://doi.org/10.24966/ncp-878x/100084","url":null,"abstract":"Swallowing and feeding difficulties associated with Neurological Impairment (NI) can impact on children’s ability to meet nutritional requirements orally and so enteral nutrition is often required.","PeriodicalId":93307,"journal":{"name":"Journal of clinical pediatrics and neonatology","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89965875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nutritional Intervention in Paediatric Gastroesophageal Reflux Disease: Clinical Case Reports","authors":"Kathryn Simpson","doi":"10.24966/ncp-878x/100079","DOIUrl":"https://doi.org/10.24966/ncp-878x/100079","url":null,"abstract":"The nutritional management of the complex needs child with impaired gastrointestinal function can be challenging.","PeriodicalId":93307,"journal":{"name":"Journal of clinical pediatrics and neonatology","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77565322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Li Yin, Kai-Fen Chang, Kyle J Nakamura, Louise Kuhn, Grace M Aldrovandi, Maureen M Goodenow
{"title":"Unique genotypic features of HIV-1 C gp41 membrane proximal external region variants during pregnancy relate to mother-to-child transmission via breastfeeding.","authors":"Li Yin, Kai-Fen Chang, Kyle J Nakamura, Louise Kuhn, Grace M Aldrovandi, Maureen M Goodenow","doi":"10.46439/pediatrics.1.003","DOIUrl":"10.46439/pediatrics.1.003","url":null,"abstract":"<p><p>Mother-to-child transmission (MTCT) through breastfeeding remains a major source of pediatric HIV-1 infection worldwide. To characterize plasma HIV-1 subtype C populations from infected mothers during pregnancy that related to subsequent breast milk transmission, an exploratory study was designed to apply next generation sequencing and a custom bioinformatics pipeline for HIV-1 gp41 extending from heptad repeat region 2 (HR2) through the membrane proximal external region (MPER) and the membrane spanning domain (MSD). MPER harbors linear and highly conserved epitopes that repeatedly elicits HIV-1 neutralizing antibodies with exceptional breadth. Viral populations during pregnancy from women who transmitted by breastfeeding, compared to those who did not, displayed greater biodiversity, more frequent amino acid polymorphisms, lower hydropathy index and greater positive charge. Viral characteristics were restricted to MPER, failed to extend into flanking HR2 or MSD regions, and were unrelated to predicted neutralization resistance. Findings provide novel parameters to evaluate an association between maternal MPER variants present during gestation and lactogenesis with subsequent transmission outcomes by breastfeeding.</p><p><strong>Importance: </strong>HIV-1 transmission through breastfeeding accounts for 39% of MTCT and continues as a major route of pediatric infection in developing countries where access to interventions for interrupting transmission is limited. Identifying women who are likely to transmit HIV-1 during breastfeeding would focus therapies, such as broad neutralizing HIV monoclonal antibodies (bn-HIV-Abs), during the breastfeeding period to reduce MTCT. Findings from our pilot study identify novel characteristics of gestational viral MPER quasispecies related to transmission outcomes and raise the possibility for predicting MTCT by breastfeeding based on identifying mothers with high-risk viral populations.</p>","PeriodicalId":93307,"journal":{"name":"Journal of clinical pediatrics and neonatology","volume":"1 1","pages":"9-20"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454918/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39440492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Child Handling Cultural Practices For Neuromotor Development In Infants In A Cohort Of African Population: A Prospective Analytical Study","authors":"N. F. Onuegbu","doi":"10.24966/NCP-878X/100063","DOIUrl":"https://doi.org/10.24966/NCP-878X/100063","url":null,"abstract":"Despite the use of many cultural-handling practices to facilitate neuromotor development in African children, there is no documentation on their purpose and effectiveness.","PeriodicalId":93307,"journal":{"name":"Journal of clinical pediatrics and neonatology","volume":"5 2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78862232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Rare Mutation In Noonan Syndrome","authors":"V. Carvalho","doi":"10.24966/ncp-878x/100060","DOIUrl":"https://doi.org/10.24966/ncp-878x/100060","url":null,"abstract":"Noonan Syndrome (NS) is a genetic disorder mainly characterized by short stature, distinctive facial features, congenital heart defects, cardiomyopathy and an increased risk to develop tumors in childhood. The incidence is estimated to be between 1:1000 and 1:2500 live births. Mutations in PTPN11 (12q24.13) are seen in 50% of cases.","PeriodicalId":93307,"journal":{"name":"Journal of clinical pediatrics and neonatology","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84039212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}