Yi-Ru Chen, F. Hsu, Cheng-Ching Yu, Chih‐Chieh Chang, Hao-Wen Cheng, Wei-Lun Sun, J. Tsai
{"title":"Use of a motion phantom to verify dose accuracy in different delivery techniques for lung tumors in SBRT","authors":"Yi-Ru Chen, F. Hsu, Cheng-Ching Yu, Chih‐Chieh Chang, Hao-Wen Cheng, Wei-Lun Sun, J. Tsai","doi":"10.21037/tro-21-14","DOIUrl":"https://doi.org/10.21037/tro-21-14","url":null,"abstract":"","PeriodicalId":93236,"journal":{"name":"Therapeutic radiology and oncology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48753044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Che-Wei Lin, P. Yu, H. Nien, Hu Chang, Ching-Jung Wu
{"title":"Comparison of stability and dosage of thermoplastic masks and vacuum bag for mediastinal cancer patients: a retrospective study","authors":"Che-Wei Lin, P. Yu, H. Nien, Hu Chang, Ching-Jung Wu","doi":"10.21037/tro-21-25","DOIUrl":"https://doi.org/10.21037/tro-21-25","url":null,"abstract":"","PeriodicalId":93236,"journal":{"name":"Therapeutic radiology and oncology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46913070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Lin, Hua-Shai Hsu, C. Feng, Chia-Hung Kao, S. Chou, Ji-An Liang, C. Chien
{"title":"Cardiovascular implantable electronic devices may tolerate high dose radiotherapy: an updated case report with long term follow-up","authors":"K. Lin, Hua-Shai Hsu, C. Feng, Chia-Hung Kao, S. Chou, Ji-An Liang, C. Chien","doi":"10.21037/tro-21-18","DOIUrl":"https://doi.org/10.21037/tro-21-18","url":null,"abstract":"","PeriodicalId":93236,"journal":{"name":"Therapeutic radiology and oncology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49264080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Case report of a rare primary intracranial malignant melanoma, reviewing the literature and guidance for management","authors":"B. Chia, Y. Leow, A. Kumar, N. Keong, M. Farid","doi":"10.21037/tro-21-32","DOIUrl":"https://doi.org/10.21037/tro-21-32","url":null,"abstract":"Primary intracranial malignant melanoma (PIMM), is a rare intracranial malignancy arising from melanocytes lining leptomeningeal tissue. It accounts for approximately 1% of all melanomas and 0.07% of all brain malignancies (1). It can be classified into 2 types—diffuse meningeal melanomatosis or solitary (discrete) solid tumours depending on imaging pattern (2). PIMMs rarely metastasize beyond the central nervous system (CNS) and are histologically similar to melanomas of other sites. They are often diagnosed after excluding the presence of extracranial lesions from careful physical examinations and positron emission tomography-computed tomography (PET-CT) imaging. Specific molecular mutations in GNAQ and GNA11 genes may also be helpful to distinguish PIMMs from metastatic melanoma (3,4). Given the rarity of this disease, there are no standard management guidelines and most of the evidence for treatment comes from shared experiences of case reports or are inferred from the treatment of metastatic melanoma. We present a recent case experience in accordance with the CARE reporting checklist (available at https://tro.amegroups.com/article/ view/10.21037/tro-21-32/rc) and referenced the evidence to guide our management decisions. Case Report","PeriodicalId":93236,"journal":{"name":"Therapeutic radiology and oncology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42700224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Imaging modalities to detect and track cancer treatment-related cardiovascular dysfunction","authors":"Kai-Hung Cheng, C. Hou, C. Hung, Yen-Wen Wu","doi":"10.21037/tro-21-17","DOIUrl":"https://doi.org/10.21037/tro-21-17","url":null,"abstract":"","PeriodicalId":93236,"journal":{"name":"Therapeutic radiology and oncology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47423622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Nievas, M. Carpano, E. Boggio, M. Casal, J. Longhino, M. A. Dagrosa
{"title":"Experimental studies for the use of “beta enhancers” (BE) in the boron neutron capture therapy (BNCT) to optimize its application in the treatment of superficial tumors","authors":"S. Nievas, M. Carpano, E. Boggio, M. Casal, J. Longhino, M. A. Dagrosa","doi":"10.21037/tro-21-24","DOIUrl":"https://doi.org/10.21037/tro-21-24","url":null,"abstract":"","PeriodicalId":93236,"journal":{"name":"Therapeutic radiology and oncology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44753651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Waldstein, W. Wang, S. Lo, B. Shivalingam, G. Fogarty, M. Carlino, A. Menzies, G. Long, A. Hong
{"title":"Melanoma brain metastases: the outcome of whole brain radiation therapy in the era of effective systemic therapy","authors":"C. Waldstein, W. Wang, S. Lo, B. Shivalingam, G. Fogarty, M. Carlino, A. Menzies, G. Long, A. Hong","doi":"10.21037/tro-21-6","DOIUrl":"https://doi.org/10.21037/tro-21-6","url":null,"abstract":"Background: Whole brain radiation therapy (WBRT) is sometimes recommended for patients with multiple melanoma brain metastases (MBM) in addition to systemic therapy and/or local therapy. We report outcomes of WBRT and identify associated factors in the era of modern systemic therapy. Methods: Ninety patients treated with WBRT between 2011 and 2018 were included. Records were analyzed for clinical and treatment characteristics, radiation techniques, systemic therapy and outcomes. Overall survival (OS) rates were calculated using the Kaplan-Meier method; factors affecting OS were assessed using the log-rank test as well as Cox regression. Results: The median age was 63 years and the median follow-up was 4.5 months. The median OS from diagnosis of MBM was 8 months (range, 1–83 months), median OS from the beginning of WBRT was 5 months (range, 0–64 months). Patients with BRAF mutation who had prior systemic treatment (n=31) had a median OS from WBRT of 4.6 versus 5.2 months for those with BRAF wild type disease (n=27). Patients with no systemic treatment prior to WBRT (n=32) had a median survival of 6.7 months (P=0.65). In multivariable analysis, the presence of neurological symptoms was associated with worse OS (P=0.029) and prior surgery with better OS (P=0.002). Conclusions: In selected patients with MBM treated with systemic therapy with known intracranial activity, WBRT is a treatment option in selected patients after local therapy (surgery and SRS). Future studies should further determine the role of systemic treatment in combination with radiotherapy (RT) in MBM patients, particularly in patients with multiple brain metastases. 16","PeriodicalId":93236,"journal":{"name":"Therapeutic radiology and oncology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43834361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Five-year survival outcomes with two different high dose rate brachytherapy schedules used in the treatment of cervical carcinoma","authors":"Mohsin Khan, M. Hussain, S. Siddiqui, Mohd Akram","doi":"10.21037/tro-21-19","DOIUrl":"https://doi.org/10.21037/tro-21-19","url":null,"abstract":"","PeriodicalId":93236,"journal":{"name":"Therapeutic radiology and oncology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48411898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yinyi Lin, Shuangshuang Huang, Tung-hao Chang, T. Chou, L. Hung, Chia-chun Huang, Jhen-Bin Lin, Jin-Ching Lin
{"title":"Prognostic significance of the preoperative hematological parameters in non-metastatic rectal cancer patients undergoing neoadjuvant chemoradiotherapy and radical surgery","authors":"Yinyi Lin, Shuangshuang Huang, Tung-hao Chang, T. Chou, L. Hung, Chia-chun Huang, Jhen-Bin Lin, Jin-Ching Lin","doi":"10.21037/tro-21-35","DOIUrl":"https://doi.org/10.21037/tro-21-35","url":null,"abstract":"","PeriodicalId":93236,"journal":{"name":"Therapeutic radiology and oncology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48619923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hao-Chih Chang, Yang-Hong Dai, P. Shen, Wei-Chou Chang, C. Lo, Jen-Fu Yang, Chun-Shu Lin, H. Chao, S. Tu, Wen-Yen Huang, Jing-Min Hwang
{"title":"Using computed tomography-based radiomics to predict outcomes for hepatocellular carcinoma patients receiving stereotactic body radiotherapy","authors":"Hao-Chih Chang, Yang-Hong Dai, P. Shen, Wei-Chou Chang, C. Lo, Jen-Fu Yang, Chun-Shu Lin, H. Chao, S. Tu, Wen-Yen Huang, Jing-Min Hwang","doi":"10.21037/tro-21-8","DOIUrl":"https://doi.org/10.21037/tro-21-8","url":null,"abstract":"Department of Radiation Oncology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan; Department of Radiology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan; Department of Medical Imaging and Radiological Science, College of Medicine, Chang Gung University, Tao-Yuan, Taiwan; Department of Medical Imaging and Intervention, LinKou Chang Gung Memorial Hospital, Tao-Yuan, Taiwan; Department of Radiation Oncology, Taipei Tzuchi Hospital, The Buddhist Tzuchi Medical Foundation, Taipei, Taiwan Contributions: (I) Conception and design: HC Chang, YH Dai; (II) Administrative support: WY Huang, JM Hwang; (III) Provision of study material or patients: WY Huang, CH Lo; (IV) Collection and assembly of data: YH Dai, CH Lo; (V) Data analysis and interpretation: YH Dai, PC Shen, YF Wang; (VI) Manuscript writing: All authors; (VII) Final approval of manuscript: All authors. Correspondence to: Shu-Ju Tu. Department of Medical Imaging and Radiological Science, College of Medicine, Chang Gung University, Tao-Yuan, Taiwan. Email: sjtu@mail.cgu.edu.tw; Wen-Yen Huang. Department of Radiation Oncology, Tri-Service General Hospital, National Defense Medical Center, No. 325, Chengong Rd., Sec. 2, Neihu, Taipei 114, Taiwan. Email: hwyyi@yahoo.com.tw; Jing-Min Hwang. Department of Radiation Oncology, Taipei Tzuchi Hospital, The Buddhist Tzuchi Medical Foundation, No. 289, Jianguo Rd., Xindian Dist., New Taipei City 231, Taiwan. Email: jm195711@ms19.hinet.net.","PeriodicalId":93236,"journal":{"name":"Therapeutic radiology and oncology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48558666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}