Hsuan-Ting Wang, Lung‐Sheng Wu, Y. Chou, Yung-Shin Yeh, Kun-Chi Yen, J. Chang, Hsiao-Chieh Huang
{"title":"Feasibility assessment of proton treatment for ventricular tachycardia—treatment planning study","authors":"Hsuan-Ting Wang, Lung‐Sheng Wu, Y. Chou, Yung-Shin Yeh, Kun-Chi Yen, J. Chang, Hsiao-Chieh Huang","doi":"10.21037/tro-21-43","DOIUrl":"https://doi.org/10.21037/tro-21-43","url":null,"abstract":"Background: Photon radiotherapy has been demonstrated as an emergent role for ablation of ventricular tachycardia (VT). Compare to photon radiotherapy, proton with rapidly distal fall off is an advantage in radiotherapy. Therefore, the feasibility assessment of a single fraction proton irradiation for VT instead of the photon therapy is investigated in this study. Methods: Two patients treated with and an implantable cardioverter-defibrillator (ICD) implantation and repeated catheter ablations were retrospective selected for study. Targeted lesions in image set, including left ventricular summit and right ventricular outflow tract septum and nearby organs at risk, were contoured by cardiologist and radiation oncologist. The target dose coverage and dose in organs at risk by using the photon volumetric arc therapy, proton wobbling and proton pencil beam scanning treatment technique were evaluated respectively. Results: In comparison of dose volume parameters and isodose distributions including R30, R50 (ratio of the 50% and 30% of prescription isodose volume to the volume of planning target volume (PTV) among three different techniques. The conformal index and homogeneity index in all type of treatment plans are demonstrated to deliver a conformal, homogeneous dose to the target area. And, showing no difference in the proton wobbling and proton pencil beam technique in nearly all result. Conclusions: This treatment planning study indicated that using the proton beam to treat VT is a feasible therapeutic option. Compared to photon therapy treatment planning, proton can offer lower radiation dose to heart and lung with the same conformal index. Nevertheless, several issues require consideration in future studies, including accurate patient localization, motion margin evaluation of respiration and heartbeat, dose measurement, and verification of small field irradiation.","PeriodicalId":93236,"journal":{"name":"Therapeutic radiology and oncology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42901482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ching-Heng Yen, Li-Tsun Shieh, Sung-Wei Lee, Chia-Chun Chen, S. Ho
{"title":"Retrospective analysis of dosimetry on hippocampal-avoidance whole-brain radiotherapy in a regional hospital","authors":"Ching-Heng Yen, Li-Tsun Shieh, Sung-Wei Lee, Chia-Chun Chen, S. Ho","doi":"10.21037/tro-22-17","DOIUrl":"https://doi.org/10.21037/tro-22-17","url":null,"abstract":"","PeriodicalId":93236,"journal":{"name":"Therapeutic radiology and oncology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41566705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Radiotherapy to the rare penile metastases of rectal adenocarcinoma: a case report","authors":"Yun-Yun Weng, Sheau-Fang Yang, Ming-Yii Huang","doi":"10.21037/tro-22-26","DOIUrl":"https://doi.org/10.21037/tro-22-26","url":null,"abstract":"","PeriodicalId":93236,"journal":{"name":"Therapeutic radiology and oncology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45560176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chung-Hsuan Lee, Yuan‐Hua Wu, W. Hsueh, T. Pao, Yung-Jen Cheng
{"title":"Contralateral neck nodal outcomes and recurrence pattern of small well-lateralized oral cavity carcinoma—a single institution experience","authors":"Chung-Hsuan Lee, Yuan‐Hua Wu, W. Hsueh, T. Pao, Yung-Jen Cheng","doi":"10.21037/tro-22-27","DOIUrl":"https://doi.org/10.21037/tro-22-27","url":null,"abstract":"","PeriodicalId":93236,"journal":{"name":"Therapeutic radiology and oncology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43832968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of adjuvant hysterectomy for bulky cervical cancer after definitive chemoradiotherapy with insufficient brachytherapy dose: a retrospective analysis","authors":"Ching-Heng Yen, Ching-Chieh Yang, Sheng-Yow Ho, Sung-Wei Lee, Chia-Chun Chen, Li-Tsun Shieh","doi":"10.21037/tro-22-12","DOIUrl":"https://doi.org/10.21037/tro-22-12","url":null,"abstract":"","PeriodicalId":93236,"journal":{"name":"Therapeutic radiology and oncology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42442027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Gogineni, Z. Fellows, W. Hrinivich, Heng Li, V. Croog, J. Wright, K. Sheikh
{"title":"Dosimetric comparison of breath-hold and free-breathing techniques in left-sided breast cancer patients treated with proton pencil beam scanning","authors":"E. Gogineni, Z. Fellows, W. Hrinivich, Heng Li, V. Croog, J. Wright, K. Sheikh","doi":"10.21037/tro-22-5","DOIUrl":"https://doi.org/10.21037/tro-22-5","url":null,"abstract":"","PeriodicalId":93236,"journal":{"name":"Therapeutic radiology and oncology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45393988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Wei, C. Shi, Chin-Cheng Chen, Sheng Huang, R. Press, J. I. Choi, C. Simone, Haibo Lin, Minglei Kang
{"title":"Recent progress in pencil beam scanning FLASH proton therapy: a narrative review","authors":"S. Wei, C. Shi, Chin-Cheng Chen, Sheng Huang, R. Press, J. I. Choi, C. Simone, Haibo Lin, Minglei Kang","doi":"10.21037/tro-22-1","DOIUrl":"https://doi.org/10.21037/tro-22-1","url":null,"abstract":"Background and Objective : Recent experimental studies using ultra-high dose rate radiation therapy (FLASH-RT) have shown improved normal tissue sparing and comparable tumor control compared to conventional dose rate RT. Pencil beam scanning (PBS) proton therapy with superior dosimetry characteristics has begun to draw attention to the delivery of conformal FLASH-RT for preclinical studies. This review aims to provide recent updates on the development of PBS FLASH-RT. Method s: The information summarized in this review article is based on search results in databases such as PubMed and search engines like Google Scholar, with keywords including pencil beam scanning, proton therapy, proton FLASH, Bragg peak FLASH, etc., with English articles from the year of 2014-2022. Content and Findings: This review summarizes of recent developments in PBS FLASH proton therapy (FLASH-PT), including PBS dose rate characterization, current delivery limitations, treatment planning, and biological investigations. Conclusions: As PBS FLASH delivery has enabled successful biological studies using transmission beams, the further improvement in PBS Bragg peak FLASH technologies will result in more advanced treatment plans associated with potentially improved outcomes.","PeriodicalId":93236,"journal":{"name":"Therapeutic radiology and oncology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43441984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Chew, Moon-Sing Lee, Jin-Cherng Chen, Tsung-Hsien Wu, W. Chiou, Hon-Yi Lin, Liang-Cheng Chen, P. Yeh, S. Hung
{"title":"Outcome of reduced-dose stereotactic radiosurgery for patients with vestibular schwannoma","authors":"C. Chew, Moon-Sing Lee, Jin-Cherng Chen, Tsung-Hsien Wu, W. Chiou, Hon-Yi Lin, Liang-Cheng Chen, P. Yeh, S. Hung","doi":"10.21037/tro-22-15","DOIUrl":"https://doi.org/10.21037/tro-22-15","url":null,"abstract":"","PeriodicalId":93236,"journal":{"name":"Therapeutic radiology and oncology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42616188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Who gains from repeat radiosurgery for progressive previously treated brain metastases? A case series","authors":"F. Ampil, C. Porter, A. Sin, T. Richards","doi":"10.21037/tro-21-41","DOIUrl":"https://doi.org/10.21037/tro-21-41","url":null,"abstract":"","PeriodicalId":93236,"journal":{"name":"Therapeutic radiology and oncology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46528867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Treating papillary tumors of the breast—role of adjuvant treatment—a narrative review","authors":"Mohsin Khan","doi":"10.21037/tro-22-19","DOIUrl":"https://doi.org/10.21037/tro-22-19","url":null,"abstract":"","PeriodicalId":93236,"journal":{"name":"Therapeutic radiology and oncology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44303637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}