International journal of cell science & molecular biology最新文献_第3页

Organ Transplantation: An Overview from History to Challenges 器官移植:从历史到挑战的概述

International journal of cell science & molecular biology Pub Date : 2018-10-01 DOI: 10.19080/IJCSMB.2018.05.555659

A. Razzaq

引用次数: 0

Why Indian men feel sad after sex 为什么印度男人做爱后会感到悲伤

International journal of cell science & molecular biology Pub Date : 2018-10-01 DOI: 10.19080/IJCSMB.2018.05.555658

R. Hajare

引用次数: 3

Undifferentiated Carcinoma of Lymph Nodes 未分化淋巴结癌

International journal of cell science & molecular biology Pub Date : 2018-09-24 DOI: 10.19080/IJCSMB.2018.05.555657

W. Onuigbo

引用次数: 0

Development and Evaluation of Antidiabetic Potential of Polyherbal Formulation in Streptozotocin Induced Animal Model 多草药制剂在链脲佐菌素诱导的动物模型中抗糖尿病潜力的开发和评价

International journal of cell science & molecular biology Pub Date : 2018-09-14 DOI: 10.19080/IJCSMB.2018.05.555656

M. Sahu

引用次数: 4

Development of Enpp1 Inhibitors as a Strategy to Activate Stimulator of Interferon Genes (STING) in Cancers and Other Diseases Enpp1抑制剂的开发作为激活癌症和其他疾病中干扰素基因刺激因子（STING）的策略

International journal of cell science & molecular biology Pub Date : 2018-09-10 DOI: 10.19080/IJCSMB.2018.05.555655

M. Kaadige

引用次数: 6

Hematological and Physiological Effects of Ketamine with and without Xylazine in Dogs 氯胺酮加与不加噻嗪对犬血液学和生理的影响

International journal of cell science & molecular biology Pub Date : 2018-08-30 DOI: 10.19080/IJCSMB.2018.05.555654

G. Yohannes

{"title":"Hematological and Physiological Effects of Ketamine with and without Xylazine in Dogs","authors":"G. Yohannes","doi":"10.19080/IJCSMB.2018.05.555654","DOIUrl":"https://doi.org/10.19080/IJCSMB.2018.05.555654","url":null,"abstract":"Ketamine hydrochloride is a dissociative anesthetic of the cyclohexylamine group used for chemical restraint and for the induction and maintenance of anesthesia in a number of species. Unlike many anesthetics, ketamine usually stimulates cardiovascular function in normal animals, causing increase in heart rate (HR) and mean arterial pressure (MAP). The use of ketamine as a sole anesthetic has been limited by muscle hypertonicity and myoclonus, violent recovery and occasional occurrence of convulsions [1]. Ketamine is combined with an alpha-2-agonist (e.g. xylazine), a benzodiazepine (e.g. diazepam) or a phenothiazine tranquillizer (e.g. acepromazine) to enhance muscle relaxation, analgesia, to prevent seizures/convulsions and prolong the duration of anesthetic effect. It is associated with a rapid onset, good to excellent sedation of one to two hours duration, excellent analgesia and smooth recovery. The analgesia and sedation are due to central nervous system depression and the muscle relaxation is due to the central inhibition of intraneural transmission [2]. Ketamine is poor in visceral analgesia. However, it can be used in combination with xylazine or diazepam to provide good visceral analgesia in case of abdominal surgery (including ovariohysterectomy) and thoracic surgery. Pain is an unpleasant sensory or emotional experience most commonly associated with potential tissue damage. The sensation of pain is a consequence of the activation of specialized receptors and neurological pathways after such pain stimuli [3,4]. Xylazine, an alpha-2 agonist used in animal experiments, stimulates alpha-2 adrenergic receptor in cerebral presynaptic nerve ends, inhibits release of catecholamines and dopamine resulting in analgesic and sedative eff ects, and hinders nerve conduction in the central nervous system leading to relaxation of striated muscles. Xylazine is usually used in combination with ketamine during anesthetic applications [5].","PeriodicalId":93190,"journal":{"name":"International journal of cell science & molecular biology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45884268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Identification and Analysis of Salt Responsive Candidate Gene Based on SSRs from Tomato (Solanum lycopersicum L.) 基于番茄SSRs的盐响应候选基因的鉴定与分析

International journal of cell science & molecular biology Pub Date : 2018-08-30 DOI: 10.19080/IJCSMB.2018.05.555653

Ja'afar Umar

引用次数: 0

Protein Expression Profile of Oral Premalignant Lesions (OPLs) 口腔癌前病变(opl)蛋白表达谱

International journal of cell science & molecular biology Pub Date : 2018-08-17 DOI: 10.19080/IJCSMB.2018.05.555652

Kamal Uddin Zaidi

{"title":"Protein Expression Profile of Oral Premalignant Lesions (OPLs)","authors":"Kamal Uddin Zaidi","doi":"10.19080/IJCSMB.2018.05.555652","DOIUrl":"https://doi.org/10.19080/IJCSMB.2018.05.555652","url":null,"abstract":"Oral cancer is a subgroup of head and neck cancer which affects various regions within oral cavity i.e., lips, tongue, salivary glands, and gums. It is the sixth most common cancer, approximately 3% of the total cancer burden and results in 128,000 annual deaths globally [1,2]. The most common type of oral cancer is oral squamous cell carcinoma (OSCC), which accounts 90% of all oral cancer cases. Patients with OSCC are often diagnosed at a late stage, thus high recurrence rate occurs after treatment, especially in those with neck lymph node metastasis [3]. Despite clinical and treatment advances, the overall 5-year survival rates for oral cancer remains low and stagnant during past few decades [4,5]. Although OSCC is commonly diagnosed through oral examination followed by histopathology and computed tomography/positron emission tomography scanning, there has been continuous interest in developing serum protein biomarkers to aid the diagnosis. Tumor antigens are promising diagnostic biomarkers for human cancers showing the clinical utility of tumor antigens, such as carcinoembryonic antigen (CEA), CA-50, CA19-9 and squamous cell carcinoma antigen (SCCA) for OSCC detection [6-9].","PeriodicalId":93190,"journal":{"name":"International journal of cell science & molecular biology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47081064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Probiotic Spore Formers Enhances Host Health 益生菌孢子形成促进宿主健康

International journal of cell science & molecular biology Pub Date : 2018-08-14 DOI: 10.19080/IJCSMB.2018.05.555651

Keerthi Tr

{"title":"Probiotic Spore Formers Enhances Host Health","authors":"Keerthi Tr","doi":"10.19080/IJCSMB.2018.05.555651","DOIUrl":"https://doi.org/10.19080/IJCSMB.2018.05.555651","url":null,"abstract":"The concept of probiotics has a long history of health claims. For example, in a Persian version of the Old Testament (Genesis 18:8), it states “Abraham owed his longevity to the consumption of sour milk. Replacing in-feed antibiotics with non-antibiotic alternatives is, therefore, an ever-increasing necessity. However, the withdrawal of all growth promoting factors is not a simple matter since this will not only affect feed efficiency but will also increase the mortality and morbidity of animals [1]. Sporeformers are capable of growth and metabolic activity only when in the vegetative state, and resort to sporulation when conditions of inadequate nutrition or other challenge to survival is experienced [2]. Currently, there is no universalclass of probiotic bacterium although the most common types available are lactic acid bacteria (e.g., Lactobacillus spp.). These bacteria are found normally in the gastrointestinal tract (GIT) of humans and animals and there is the vague notion that the use of indigenous or commensal microorganisms is somehow restoring the natural microflora to the gut. A second class comprises those that are not normally found in the GIT. For example, Saccharomyces boulardii has been shown to be effective in preventing the recurrence of Clostridium difficile-induced pseudo membranous colitis [3] as well as the antagonistic action of Escherichia coli [4]. S. boulardii products are currently being marketed for human use. Within this group of allochthonous probiotic microbes are the sporeforming bacteria, normally members of the genus Bacillus. Here, the product is used in the spore form and thus can be stored indefinitely on the shelf. The use of spore-based products raises a number of questions though. Since the bacterial species being used are not considered resident members of the gastrointestinal microflora how do they exert a beneficial effect? Because the natural life cycle of Initial efforts to document a physiological impact of probiotic bacteria often focus on the following three criteria:","PeriodicalId":93190,"journal":{"name":"International journal of cell science & molecular biology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47401930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pathogenecity of Pseudomonas anguilliseptica Infection in Goldfish (Cyprinus Carpio) 金鱼（Cyprinus Carpio）感染鳗毒假单胞菌的病原学研究

International journal of cell science & molecular biology Pub Date : 2018-07-19 DOI: 10.19080/IJCSMB.2018.04.555650

Ajeng Aekanurmaningdyah

引用次数: 1