Archives of orthopedics and rheumatology最新文献_第4页

Deep Vein Thrombosis (DVT) in an Operated Sub Trochanteric Fracture Femur 深静脉血栓形成(DVT)在股骨粗隆下骨折手术

Archives of orthopedics and rheumatology Pub Date : 2018-01-01 DOI: 10.22259/2639-3654.0101006

N. Dhaniwala, Malhar Jadhav, Venkatesh Dasari, Vrushabh U. Kumbhare

引用次数: 0

Lower Limb Bone Shortened by 10 Cm and Replantation Extension in Children 儿童下肢骨缩短10cm及再植延长

Archives of orthopedics and rheumatology Pub Date : 2018-01-01 DOI: 10.22259/2639-3654.0101005

Changliang Ou, Xincheng Tang, Yonggen Zou, Xuchao Luo

引用次数: 1

Acute Febrile Polyarthritis Revealing very Late-Onset Behcet's Disease 显示迟发性白塞病的急性发热性多关节炎

Archives of orthopedics and rheumatology Pub Date : 2018-01-01 DOI: 10.22259/2639-3654.0102001

S. Bouomrani, M. Nefoussi

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Drug Development in Unani System of Medicine: Reverse Pharmacological Approach Unani医学系统中的药物开发:反向药理学方法

Archives of orthopedics and rheumatology Pub Date : 2018-01-01 DOI: 10.22259/2639-3654.0102002

Imtiyaz Ahmad Mir, G. Sofi, S. Mehfooz, Khadija Abdul Hafeez, Ghousia islam

引用次数: 0

Minimally Invasive Spine Osteosynthesis (MISO) Technique Versus Traditional and Paraspinal Posterior Open Approaches for Treatment of Thoracolumbar Spine Fractures 微创脊柱植骨术与传统椎旁后路开放入路治疗胸腰椎骨折的比较

Archives of orthopedics and rheumatology Pub Date : 2018-01-01 DOI: 10.22259/2639-3654.0102003

Bahaa Ali kornah Hesham, Mohamed safwat Mohamed, Abdelaziz Mohamed, Ibrahim abuelesoud Tharwat, A. Ghany, Nagy Saleem, Mohamed Abdel-AAl

引用次数: 0

Assesment of Common Exon 10 MEFV Gene Mutations in Patients with Refractory Rheumatoid Arthritis 难治性类风湿关节炎患者常见外显子10 MEFV基因突变的评估

Archives of orthopedics and rheumatology Pub Date : 2018-01-01 DOI: 10.22259/2639-3654.0101001

A. Mirzaei, S. Kolahi, Fatima Pashaei-Asl, S. Esmaeili

{"title":"Assesment of Common Exon 10 MEFV Gene Mutations in Patients with Refractory Rheumatoid Arthritis","authors":"A. Mirzaei, S. Kolahi, Fatima Pashaei-Asl, S. Esmaeili","doi":"10.22259/2639-3654.0101001","DOIUrl":"https://doi.org/10.22259/2639-3654.0101001","url":null,"abstract":"Objective: Rheumatoid arthritis (RA) is a common chronic inflammatory arthritis with many flare ups in some patients. New studies showed the importance of Mediterranean fever gene mutations in certain inflammatory conditions. We investigated molecular mutation in exon 10 of MEFV gene in patients with refractory RA and healthy individuals as a control group in North-West of Iran. Methods: We conducted thirty four patients with refractory RA and fifty healthy controls in this study. Their DNA samples were analyzed with specific primers, standard PCR and Sequencing techniques. We studied the most common exon 10 variations on MEFV gene which include; M680I, M694V, M694I and V726A. Results: The mean ages of patients with refractory RA were 43.8 ± 7.7 years and disease duration was 49.8 ± 7.36 months. The mean of DAS 28 (Disease Activity score) of patients with refractory RA was about 4.2 ± 0.51. The mean ages of healthy control cases were 45.4 ± 8.27 years. The result of DNA sequencing showed no mutations in common exon 10 variations of MEFV gene in both groups. Conclusion: According to the result, we found no association between severity of RA and common exon 10 MEFV gene mutations.","PeriodicalId":93165,"journal":{"name":"Archives of orthopedics and rheumatology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68287725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0