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Archives of autoimmune diseases最新文献

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Positive-DAT and autoimmune manifestations in patients with JAK2V617F mutation JAK2V617F突变患者的DAT阳性和自身免疫表现
Archives of autoimmune diseases Pub Date : 2023-11-10 DOI: 10.46439/autoimmune.4.015
R. Akoum, Rita Chidiac, Joseph Yammine, M. Saade, E. Brihi
{"title":"Positive-DAT and autoimmune manifestations in patients with JAK2V617F mutation","authors":"R. Akoum, Rita Chidiac, Joseph Yammine, M. Saade, E. Brihi","doi":"10.46439/autoimmune.4.015","DOIUrl":"https://doi.org/10.46439/autoimmune.4.015","url":null,"abstract":"Objective: Myeloproliferative neoplasms (MPN) are occasionally associated with autoimmune manifestations. The prevalence of positive direct antiglobulin test (DAT) in patients with JAK2V617F mutation is not yet known. Methods: We conducted a cohort study of all consecutive patients with JAK2V617F mutation who underwent DAT at presentation from 2010 to 2022. We also looked for the prevalence of autoimmune diseases (AIDs) and relation to thrombosis. Results: Fifty nine patients formed the cohort, 22 females and 37 males, with a mean age of 65 years. The median follow-up time was 90 months. A positive-DAT was found in 6 to 7% of essential thrombocythemia (ET) and polycythemia vera (PV) patients, 60% of primary myelofibrosis (PMF) patients and 50% of myelodysplasia/myeloproliferation (MDS/MPN) patients with or without anemia. Autoimmune manifestations were present in 13% of patients with PV and 50% of those with MDS/MPN features. Overall, 25% of patients had autoimmune phenomena including the 15% with positive-DAT. Conclusion: In patients with JAK2V617F mutation, those with PMF and MDS/MPN subtypes are most likely to display a positive-DAT results and autoimmune manifestations (≥ 50%). Patients with PV and ET are less likely to exhibit autoimmune manifestations (≤ 10%). No correlation with the occurrence of thrombosis was seen.","PeriodicalId":93164,"journal":{"name":"Archives of autoimmune diseases","volume":"61 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139280754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
COVID-19 and the liver: Uncovering the hidden culprit behind liver injury COVID-19和肝脏:揭露肝损伤背后的隐藏罪魁祸首
Archives of autoimmune diseases Pub Date : 2023-08-23 DOI: 10.46439/autoimmune.4.014
Zeppieri Marco, Grando Martina
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引用次数: 0
Stromal cells set the myeloma bone marrow on fire 基质细胞使骨髓瘤骨髓燃烧起来
Archives of autoimmune diseases Pub Date : 2022-12-01 DOI: 10.46439/autoimmune.3.013
{"title":"Stromal cells set the myeloma bone marrow on fire","authors":"","doi":"10.46439/autoimmune.3.013","DOIUrl":"https://doi.org/10.46439/autoimmune.3.013","url":null,"abstract":"","PeriodicalId":93164,"journal":{"name":"Archives of autoimmune diseases","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89136112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A unified viral theory of autoimmunity 自身免疫的统一病毒理论
Archives of autoimmune diseases Pub Date : 2021-12-31 DOI: 10.46439/autoimmune.2.011
{"title":"A unified viral theory of autoimmunity","authors":"","doi":"10.46439/autoimmune.2.011","DOIUrl":"https://doi.org/10.46439/autoimmune.2.011","url":null,"abstract":"","PeriodicalId":93164,"journal":{"name":"Archives of autoimmune diseases","volume":"88 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83063873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rheumatic fever: A classical model of a postinfection autoimmune disease and vaccine perspectives 风湿热:感染后自身免疫性疾病的经典模型和疫苗观点
Archives of autoimmune diseases Pub Date : 2021-12-31 DOI: 10.46439/autoimmune.2.012
{"title":"Rheumatic fever: A classical model of a postinfection autoimmune disease and vaccine perspectives","authors":"","doi":"10.46439/autoimmune.2.012","DOIUrl":"https://doi.org/10.46439/autoimmune.2.012","url":null,"abstract":"","PeriodicalId":93164,"journal":{"name":"Archives of autoimmune diseases","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87307982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Occurrence of cervical spine arthritis highly responsive to adalimumab in a patient with psoriatic peripheral arthritis and longstanding remission while on etanercept therapy 银屑病周围性关节炎患者对阿达木单抗高度反应的颈椎关节炎的发生，在依那西普治疗期间长期缓解
Archives of autoimmune diseases Pub Date : 2021-07-27 DOI: 10.46439/autoimmune.1.009
{"title":"Occurrence of cervical spine arthritis highly responsive to adalimumab in a patient with psoriatic peripheral arthritis and longstanding remission while on etanercept therapy","authors":"","doi":"10.46439/autoimmune.1.009","DOIUrl":"https://doi.org/10.46439/autoimmune.1.009","url":null,"abstract":"","PeriodicalId":93164,"journal":{"name":"Archives of autoimmune diseases","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85737736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of estrogen in neuroimmunomodulation in the periphery and onset of autoimmune dysfunction 雌激素在外周神经免疫调节和自身免疫功能障碍发病中的作用
Archives of autoimmune diseases Pub Date : 2021-07-27 DOI: 10.46439/autoimmune.1.007
{"title":"Role of estrogen in neuroimmunomodulation in the periphery and onset of autoimmune dysfunction","authors":"","doi":"10.46439/autoimmune.1.007","DOIUrl":"https://doi.org/10.46439/autoimmune.1.007","url":null,"abstract":"","PeriodicalId":93164,"journal":{"name":"Archives of autoimmune diseases","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87888749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Opsoclonus myoclonus syndrome and hyper IgM syndrome in the pediatric patient: A nonimmunosuppressive approach 小儿虚阵肌阵挛综合征和高IgM综合征:一种非免疫抑制方法
Archives of autoimmune diseases Pub Date : 2021-07-27 DOI: 10.46439/autoimmune.1.010
{"title":"Opsoclonus myoclonus syndrome and hyper IgM syndrome in the pediatric patient: A nonimmunosuppressive approach","authors":"","doi":"10.46439/autoimmune.1.010","DOIUrl":"https://doi.org/10.46439/autoimmune.1.010","url":null,"abstract":"","PeriodicalId":93164,"journal":{"name":"Archives of autoimmune diseases","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82137470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
iBALT and nodular lymphoid hyperplasia in TNF-overexpressing mice tnf -过表达小鼠的iBALT与结节性淋巴样增生
Archives of autoimmune diseases Pub Date : 2021-07-27 DOI: 10.46439/autoimmune.1.006
{"title":"iBALT and nodular lymphoid hyperplasia in TNF-overexpressing mice","authors":"","doi":"10.46439/autoimmune.1.006","DOIUrl":"https://doi.org/10.46439/autoimmune.1.006","url":null,"abstract":"","PeriodicalId":93164,"journal":{"name":"Archives of autoimmune diseases","volume":"73 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86352884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Role Of IL-16 as a lymphocyte attractant appears to be conserved through phylogeny: preliminary evidence that recombinant human IL-16 preferentially attracts regulatory lymphocytes in the amphibian, Xenopus laevis IL-16作为淋巴细胞引诱剂的作用似乎在系统发育中是保守的:初步证据表明重组人IL-16在两栖动物非洲爪蟾中优先吸引调节性淋巴细胞
Archives of autoimmune diseases Pub Date : 2021-07-27 DOI: 10.46439/autoimmune.1.008
{"title":"The Role Of IL-16 as a lymphocyte attractant appears to be conserved through phylogeny: preliminary evidence that recombinant human IL-16 preferentially attracts regulatory lymphocytes in the amphibian, Xenopus laevis","authors":"","doi":"10.46439/autoimmune.1.008","DOIUrl":"https://doi.org/10.46439/autoimmune.1.008","url":null,"abstract":"","PeriodicalId":93164,"journal":{"name":"Archives of autoimmune diseases","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84512438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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