Frontiers of oral and maxillofacial medicine最新文献

{"title":"Complex techniques of eyelid reconstruction following extensive basal cell carcinoma resection","authors":"A. Rokohl, A. Kopecký, P. A. W. Matos, Yongwei Guo, V. Kakkassery, L. Heindl","doi":"10.21037/FOMM-21-11","DOIUrl":"https://doi.org/10.21037/FOMM-21-11","url":null,"abstract":"Basal cell carcinoma (BCC) is one of the most common malignant tumors overall and even the most common malignant tumors in ophthalmology. In most cases, surgical resection followed by an ophthalmoplastic reconstruction is the current gold standard for the treatment of periocular BCC. Histopathologic analysis can be performed both as a frozen section examination, Mohs micrographic surgery, or as a rapid embedding analysis, depending on the surgeon’s preference or the in-house standard. A histopathologic workup is essential not only for confirming the diagnosis and determining resection status but especially for identifying infiltrating growing subtypes, as this also influences postoperative follow-up and prognosis. A wide range of various reconstruction methods allow individualized defect coverage with mostly good cosmetically and functionally results. The basic principle is to restore the anatomy with an anterior and posterior eyelid lamella. The selection of the appropriate technique depends not only on the vertical and horizontal defect size, defect localization, or potential eyelid edge involvement but also significantly on the patient’s age, available tissue (e.g., skin), the patient’s preference, and especially the surgeon’s experience. For smaller, partial, or penetrating defects, direct wound closure can be performed. However, for greater defects more complex reconstruction techniques including Tenzel’s rotational plasty, Hughes flap, CutlerBeard plastic, Mustardé lid Switch flap, tarsomarginal grafts according to Huebner, or V-Y glabella flap are necessary, dependently on the size and the location of the defect. However, in advanced findings with infiltration of the orbit, orbital exenteration is unavoidable in some cases. Postoperative regular follow-up is essential to identify potential complications in an early stage.","PeriodicalId":93098,"journal":{"name":"Frontiers of oral and maxillofacial medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45415879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term skeletal stability following orthognathic surgery with counter-clockwise and clockwise rotation of the maxillo-mandibular complex: report of three cases","authors":"Rafael Correia Cavalcante, Otávio Giambarresi Delorenzi, L. Klüppel","doi":"10.21037/FOMM-20-32","DOIUrl":"https://doi.org/10.21037/FOMM-20-32","url":null,"abstract":": The aim of the present study is to evaluate the long-term postoperative skeletal stability after orthognathic surgery with counter-clockwise rotation (CCWR) or with clockwise rotation (CWR) of the maxillo-mandibular complex. Three patients were submitted to orthognathic surgery associated with CCWR and CWR. Lateral cephalometric radiographs were obtained in centric relation for each patient, one day before surgery (T1), 1 week after surgery (T2) and 1 year after surgery (T3). Cephalometric angles analysed were: SN-OP, SN-A, SN-B, SN-Pg, and SN-Ar. Angular changes on occlusal plane (OP), condylar position, maxilar, mandibular, and pogonium prognathism were analysed. Maxilar, mandibular, and pogonium prognathism linear changes were also recorded in millimeters. Patients had no signs and symptoms of temporo-mandibular joints pathology. Patients 1 and 2 were submitted to orthognathic surgery with CCWR. Patient 1 presented an OP decrease on T2, from 6.37° to 4.01°. On T3, however, a 2.17° relapse was observed. Patient 2 presented an OP decrease on T2, from 8.14° to 3.45°. On T3, however, a 0.54° relapse was observed. Patient 3 was submitted to orthognathic surgery with CWR. It was observed an increase in OP angulation on T2, from 6.16° to 16.13°. On T3, however, it was observed a 7.57° relapse. Regarding OP stability following orthognathic surgery with CCWR and CWR, results of the present article are consistent with of some previous published studies. More cases should be followed and more research in this area are necessary to validate these approaches to avoid unsuccessful cases or to anticipate unwanted results. vertical maxillary hypoplasia; anteroposterior mandibular hypoplasia; high mandibular plane angulation; and Class I, Class II (most common), or Class III malocclusion with or without an anterior bite. HOP individuals may benefit from a MMC counterclockwise rotation (CCWR). LOP facial type presents some features: decreased OP angle (<4°); low mandibular plane angle; prominent mandibular gonial angles; strong chin relative to mandibular dental alveolus; and Class I, Class II, or occasionally Class III relationships. Individuals with LOP facial types may benefit from a MMC clockwise rotation (CWR). Maxillo-mandibular complex is routinely expressed by a triangle, which can be rotated in or counter-clockwise","PeriodicalId":93098,"journal":{"name":"Frontiers of oral and maxillofacial medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45514172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Edentulism (missing teeth) and brain central nervous system (CNS) deafferentation: a narrative review","authors":"Dani Stanbouly, Qingcong Zeng, Y. Jou, S. Chuang","doi":"10.21037/fomm-21-117","DOIUrl":"https://doi.org/10.21037/fomm-21-117","url":null,"abstract":"","PeriodicalId":93098,"journal":{"name":"Frontiers of oral and maxillofacial medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49135046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Different responses of heterogeneous graft presentations in bone reconstructions during sinus lift elevation surgery: an immunolabeling and histomorphometric study performed in rabbits","authors":"N. Siqueira, Ana Cláudia Ervolino da Silva, R. Pereira, E. Hochuli-Vieira, P. N. Lisboa-Filho, Ciro Borges Duailibe de Deus, R. Okamoto","doi":"10.21037/fomm-21-45","DOIUrl":"https://doi.org/10.21037/fomm-21-45","url":null,"abstract":"","PeriodicalId":93098,"journal":{"name":"Frontiers of oral and maxillofacial medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42490130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral rehabilitation through the application of a xenogenous bone graft prior to placement of a dental implant: a case report with 9 years of follow-up","authors":"Paulo Martins Ferreira, William Phillip Pereira da Silva, Felipe R. Ferreira, Gabriel Ramalho Ferreira, Paulo Fukasji Yamaguti, L. A. Delanora, A. Consolaro, L. Faverani","doi":"10.21037/fomm-21-46","DOIUrl":"https://doi.org/10.21037/fomm-21-46","url":null,"abstract":"","PeriodicalId":93098,"journal":{"name":"Frontiers of oral and maxillofacial medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48120340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lessons learned from the multidisciplinary UK National Flap Registry initiative and plans for the future","authors":"Michael Ho, A. Schache, M. Nugent, A. Hazari","doi":"10.21037/fomm-21-2","DOIUrl":"https://doi.org/10.21037/fomm-21-2","url":null,"abstract":"","PeriodicalId":93098,"journal":{"name":"Frontiers of oral and maxillofacial medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48134011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The job to be done with biofilm and titanium implants","authors":"O. Jensen, E. Weiss, D. Grainger","doi":"10.21037/FOMM-21-54","DOIUrl":"https://doi.org/10.21037/FOMM-21-54","url":null,"abstract":"© Frontiers of Oral and Maxillofacial Medicine. All rights reserved. Front Oral Maxillofac Med 2021;3:21 | http://dx.doi.org/10.21037/fomm-21-54 Once, Clayton Christensen was asked about the prospect of starting a new dental implant company when there were already hundreds of implant companies around the world. “If you proceed,” he advised, “you have to ask one question: What is the job to be done?” Interestingly, the job to be done remains one that the dental profession has wrestled with from the beginning: to inhibit or arrest the development of microbial biofilms on titanium surfaces of an intraoral implant. The peculiarity of the oral cavity is that endogenous b a c t e r i a a n d f u n g u s — c o m m e n s a l , p a t h o g e n i c , opportunistic—all evolved a highly stable self-regulating, and often symbiotic, environment for the dentate niche, termed biofilm that supplements their planktonic growth strategy. A biofilm is a community of aggregated microbial cells organized as micro-communities, colonizing solid oral surfaces in contact with liquids and air. And this unique biofilm strategy is several orders of magnitude more resistant to natural sheer forces from deglutition, mastication and salivary flow that otherwise readily clear nonadherent pathogens from the mouth. The biofilm matrix comprises an aqueous network of mixed nucleic acids, polysaccharides, proteins and lipids, all of microbial origin. The interacting extracellular polymeric substances (EPS) are non-covalently associated into a robust matrix to embed and protect aggregated bacterial and fungal cells within the biofilm. Microbe-microbe, microbe-EPS, microbe-liquid/air, and microbe-substrate interactions all determine formation, properties and behaviors of biofilm. Polymicrobial biofilms are most common, representing complex dynamic communities of diverse, spatially aggregated organisms. One characteristic feature of biofilm is its physical barrier functions that provide microbial protection, particularly in the deeper layers. Biofilm protections are diverse, spanning microbial physical resistance to phagocyte engulfment and biofilm extraction, and reduced exposure to antimicrobials by limited biofilm permeation. Additionally, microbial density within EPS highly favors plasmid exchange, facilitating the transfer of resistance genes and virulence factors. Other genetic programming and regulation also occurs within biofilms, allowing populations of pathogens to undergo senescence to avoid susceptibility to metabolically targeted antimicrobials. Sleeper or persister cells re-awaken post-exposure to exert virulence. Furthermore, should the biofilm become mechanically or pharmacologically disrupted, they readily and rapidly reform in the oral cavity within several hours. Biofilm, therefore, is highly refractory to elimination from the oral niche. Importantly, commensal and probiotic endogenous oral biofilms are an essential component of oral health and therefore should not be ","PeriodicalId":93098,"journal":{"name":"Frontiers of oral and maxillofacial medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45579438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Solitary mucosal neuroma of the gingiva without multiple endocrine neoplasia type 2B: a rare case report and literature review","authors":"C. Qiu, Lizhen Wang, Huiwen Chen, Zhongchen Song","doi":"10.21037/fomm-20-80","DOIUrl":"https://doi.org/10.21037/fomm-20-80","url":null,"abstract":"Mucosal neuroma (MN) is a benign neural tumor of peripheral nerves histologically characterized by irregular tortuous bundles of nerve cells with prominent perineurium that lie scattered throughout the submucosa. The tumor is usually associated with the multiple endocrine neoplasia type 2B (MEN 2B) but rarely occurs without the other components of MEN 2B. A 29-year-old woman presented to our outpatient department with an upper anterior teeth gingiva painless mass for 2-year. Intraoral examination revealed a small, tough, basal wide, well-defined mass in the labial gingival papilla between maxillary central incisor. Excisional biopsy showed that it was characterized by nerve bundles in various sizes surrounded by normal connective tissue in the submucosa under HE staining; Immunohistochemically, the mass showed strongly positive staining of S-100 protein, NSE, NF and weakly positive of EMA. The Laboratory examination and ultrasonography showed no signs of MEN 2B. In the first and second 6 months of follow-up, there was no evidence of recurrence and other components of MEN 2B. The patient was asymptomatic and she is still being followed up every 6 months. Based on these features, the lesion was finally diagnosed as a solitary gingival MN. In summary, this study showed a rare solitary MN in the gingiva papilla without MEN 2B that has not been reported yet. The histopathological evaluation can be helpful in the differential diagnosis of MN. It is hoped that a greater understanding of solitary MN without MEN 2B in the oral cavity will avoid potential misdiagnosis, and contribute to determining the correct management, which appears to be complete surgical excision with close follow-up for recurrence and other components of MEN 2B surveillance.","PeriodicalId":93098,"journal":{"name":"Frontiers of oral and maxillofacial medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44455743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The implant-abutment connection and its impact on prevention of peri-implant diseases and crestal bone stability—an academic and clinical evaluation of the literature","authors":"G. Romanos","doi":"10.21037/fomm-21-73","DOIUrl":"https://doi.org/10.21037/fomm-21-73","url":null,"abstract":"","PeriodicalId":93098,"journal":{"name":"Frontiers of oral and maxillofacial medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42014833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Narrative review: craniofacial bone regeneration—where are we now?","authors":"Hadi Khazaal, J. Helman","doi":"10.21037/fomm-21-9","DOIUrl":"https://doi.org/10.21037/fomm-21-9","url":null,"abstract":"","PeriodicalId":93098,"journal":{"name":"Frontiers of oral and maxillofacial medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46648808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}