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Amlodipine and Landmark Trials: A Review 氨氯地平和标志性试验综述
Journal of cardiology and cardiovascular sciences Pub Date : 2021-07-30 DOI: 10.29245/2578-3025/2021/3.1215
M. Yunus Khan, Sadanand R Shetty, A. Oomman, P. Jain, K. Gaurav
{"title":"Amlodipine and Landmark Trials: A Review","authors":"M. Yunus Khan, Sadanand R Shetty, A. Oomman, P. Jain, K. Gaurav","doi":"10.29245/2578-3025/2021/3.1215","DOIUrl":"https://doi.org/10.29245/2578-3025/2021/3.1215","url":null,"abstract":"High blood pressure is considered one of the major risk factors for heart disease. In addition to evidence of low heart disease and death with adequate control of blood pressure, antihypertensive treatment is still less effective in clinical practice. It is well documented that there is a decrease in cardiovascular events, such as stroke and MI, with potent therapies to combat high blood pressure. This, however, is generally believed to be the result of a phase. This review paper includes and focuses on evidence from clinical trials in support of amlodipine as a first-line anti-hypertensive agent, showing how its unique properties can provide better cardiovascular protection compared to other antihypertensive agents to prevent stroke and cardiovascular disease. Evidence from the many randomized controlled trials presented below shows that amlodipine has excellent efficacy and safety, as a first-rate anti-hypertensive agent not only to control BP but also to safely improve patient outcomes. Patients treated with this drug have benefited as they have fewer hospitals and lower rates of recovery. Its unique mechanism of action leads to a reduction in the development of atherosclerosis. In addition, amlodipine with effective BP control for 24 hours may also be helpful as an adjunct to the treatment of patients with renal impairment by reducing the progression of end-stage renal disease.","PeriodicalId":93019,"journal":{"name":"Journal of cardiology and cardiovascular sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42933245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Hemodynamics in the Aorta and Pulmonary Arteries of Congenital Heart Disease Patients: A Mini Review 先天性心脏病患者主动脉和肺动脉的血流动力学:一个小综述
Journal of cardiology and cardiovascular sciences Pub Date : 2021-06-30 DOI: 10.29245/2578-3025/2021/2.1213
L. Johnston, M. Boumpouli, A. Kazakidi
{"title":"Hemodynamics in the Aorta and Pulmonary Arteries of Congenital Heart Disease Patients: A Mini Review","authors":"L. Johnston, M. Boumpouli, A. Kazakidi","doi":"10.29245/2578-3025/2021/2.1213","DOIUrl":"https://doi.org/10.29245/2578-3025/2021/2.1213","url":null,"abstract":"Congenital heart disease, which affects more than one million newborns globally each year, contributes to an increased risk of cardiovascular disease and ultimately reduced life expectancy. Computational fluid dynamics (CFD) enables detailed, non-invasive characterization of complex physiological pressure and flow fields, thus improving our understanding of congenital heart disease hemodynamics. In recent years, this has driven clinical decision-making, surgical planning, and the evaluation of innovative surgical techniques. In this mini review, CFD methods applied to the study of congenital abnormalities, with a focus on the aorta and pulmonary bifurcation, are discussed. The clinical relevance and future directions of CFD modelling are also reviewed.","PeriodicalId":93019,"journal":{"name":"Journal of cardiology and cardiovascular sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43295955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Commentary: Description of the Position and Performance of an Echocardiogram by Subcostal View During the Prone Position in A Patient with Severe Pneumonia Caused by COVID-19 解说词：一例新冠肺炎引起的重症肺炎患者俯卧位超声心动图的位置和表现描述
Journal of cardiology and cardiovascular sciences Pub Date : 2021-01-19 DOI: 10.29245/2578-3025/2021/1.1210
César Del Castillo Gordillo, Mario Alfaro Diaz
{"title":"Commentary: Description of the Position and Performance of an Echocardiogram by Subcostal View During the Prone Position in A Patient with Severe Pneumonia Caused by COVID-19","authors":"César Del Castillo Gordillo, Mario Alfaro Diaz","doi":"10.29245/2578-3025/2021/1.1210","DOIUrl":"https://doi.org/10.29245/2578-3025/2021/1.1210","url":null,"abstract":"","PeriodicalId":93019,"journal":{"name":"Journal of cardiology and cardiovascular sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48541606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
https://www.cardiologyresearchjournal.com/articles/what-are-adults-illness-representations-mood-and-quality-of-life-after-myocardial-infarction.html https://www.cardiologyresearchjournal.com/articles/what-are-adults-illness-representations-mood-and-quality-of-life-after-myocardial-infarction.html
Journal of cardiology and cardiovascular sciences Pub Date : 2020-10-01 DOI: 10.29245/2578-3025/2020/4.1205
Elizabeth P. Tolmie, G. Lindsay, P. Belcher
{"title":"https://www.cardiologyresearchjournal.com/articles/what-are-adults-illness-representations-mood-and-quality-of-life-after-myocardial-infarction.html","authors":"Elizabeth P. Tolmie, G. Lindsay, P. Belcher","doi":"10.29245/2578-3025/2020/4.1205","DOIUrl":"https://doi.org/10.29245/2578-3025/2020/4.1205","url":null,"abstract":"","PeriodicalId":93019,"journal":{"name":"Journal of cardiology and cardiovascular sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45995242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Shockwave Coronary Lithoplasty for the Treatment of Under-Expanded Stent 冲击波冠状动脉成形术治疗支架扩张不足
Journal of cardiology and cardiovascular sciences Pub Date : 2020-07-01 DOI: 10.29245/2578-3025/2020/3.1202
E. J. Tassone, C. Tripolino, G. Morabito, Placido Grillo, B. Missiroli
{"title":"Shockwave Coronary Lithoplasty for the Treatment of Under-Expanded Stent","authors":"E. J. Tassone, C. Tripolino, G. Morabito, Placido Grillo, B. Missiroli","doi":"10.29245/2578-3025/2020/3.1202","DOIUrl":"https://doi.org/10.29245/2578-3025/2020/3.1202","url":null,"abstract":"The presence of coronary calcification is a hard challenge for the interventional cardiologist, as it is associated with incomplete stent expansion and frequently stent failure. In recent years, innovative techniques has been developed to treat coronary calcific lesions such as rotational atherectomy. However, many of them are burdened with an increased procedural risk. Recently, a new technique called “Shockwave Coronary Lithoplasty System” has been introduced in order to treat calcific coronary lesions with greater safety. Shockwave procedure allows treating the most calcific coronary lesions with simplicity and safety. This system employs the sound waves, similar to that used for treating kidney stone, in order to crush the calcific lesions. In this minireview we explain the characteristics of the method and we provide a description of the technique in detail on the basis of the preliminary experience of the first cases. In particular, we will demonstrate that this technique is more effective and safer than traditional techniques employing atherectomy, also providing for the first time a therapeutic chance for the treatment of under-expanded stents in many clinical contexts. *Correspondence to: Eliezer Joseph Tassone, Department of Cardiac Surgery, Cardiology Unit, Sant ’Anna Hospital, Catanzaro, Italy, E-mail: eliezerjoseph.tassone@gmail.com","PeriodicalId":93019,"journal":{"name":"Journal of cardiology and cardiovascular sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43173995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Left Atrial Appendage Occlusion in Patients with Non-Valvular Atrial Fibrillation and History of Intracranial Hemorrhage: A Review 非瓣膜性心房颤动患者左心耳闭塞与颅内出血史的回顾
Journal of cardiology and cardiovascular sciences Pub Date : 2020-05-01 DOI: 10.29245/2578-3025/2020/2.1197
S. Hosseini, Cristina Pecci, M. Ajmal
{"title":"Left Atrial Appendage Occlusion in Patients with Non-Valvular Atrial Fibrillation and History of Intracranial Hemorrhage: A Review","authors":"S. Hosseini, Cristina Pecci, M. Ajmal","doi":"10.29245/2578-3025/2020/2.1197","DOIUrl":"https://doi.org/10.29245/2578-3025/2020/2.1197","url":null,"abstract":"Atrial Fibrillation (AF) is associated with an increased risk of thromboembolism due to formation of intracardiac thrombus mostly in left atrial appendage. Anticoagulant agents are used to reduce the risk of thromboembolism but have concerning bleeding side effect, making their use very challenging particularly in patients with high HAS-BLED risk score. WATCHMAN device (Boston Scientific, St. Paul, Minnesota) is a Left Atrial Appendage Occlusion (LAAO) device, which was tested in two major randomized trials. PROTECT AF (Percutaneous Left Atrial Appendage Closure for Stroke Prophylaxis in Patients with Atrial Fibrillation) trial, and PREVAIL (Prospective Randomized Evaluation of the WATCHMAN Left Atrial Appendage Closure Device in Patients with Atrial Fibrillation versus Long Term warfarin Therapy) trial, both evaluated WATCHMAN device’s safety and efficacy compared to warfarin. These trials showed WATCHMAN device to be noninferior to warfarin. However, patients with history of intracranial hemorrhage were excluded from these trials due to concern of increased recurrent bleeding in presence of perioperative use of anticoagulation. Purpose of this review is to evaluate existing evidence and share our experience of LAAO in this high-risk population.","PeriodicalId":93019,"journal":{"name":"Journal of cardiology and cardiovascular sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42262196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Cardiac Sarcoidosis: Role of Multimodality Imaging for Diagnosis and Treatment 心脏结节病：多模态成像在诊断和治疗中的作用
Journal of cardiology and cardiovascular sciences Pub Date : 2020-04-01 DOI: 10.29245/2578-3025/2020/2.1194
D. Bhandare, A. Kottam
{"title":"Cardiac Sarcoidosis: Role of Multimodality Imaging for Diagnosis and Treatment","authors":"D. Bhandare, A. Kottam","doi":"10.29245/2578-3025/2020/2.1194","DOIUrl":"https://doi.org/10.29245/2578-3025/2020/2.1194","url":null,"abstract":"The clinical presentation of cardiac sarcoidosis (CS) ranges from an incidentally discovered condition to heart failure and sudden death. The diagnosis of CS is tough, and as a result, CS is often under-recognized in clinical practice. CS is mostly noted in the setting of systemic sarcoidosis, though isolated CS can occur. Frequently clinical criteria require the diagnosis of extracardiac disease in order to establish the diagnosis of CS in the absence of having a positive endomyocardial biopsy. While endomyocardial biopsy provides a high specificity for diagnosing CS, this invasive test has a limited sensitivity. There is incomplete knowledge of disease development and a deficient consensus on the ideal methods for disease recognition. We discuss CS in general, the clinical disease, diagnostic algorithms, latest guidelines and management.","PeriodicalId":93019,"journal":{"name":"Journal of cardiology and cardiovascular sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41421512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Digital Health: New Approaches in Hypertension Management 数字健康:高血压管理的新方法
Journal of cardiology and cardiovascular sciences Pub Date : 2020-02-01 DOI: 10.29245/2578-3025/2020/1.1186
J. Kitt, R. Fox, K. Tucker
{"title":"Digital Health: New Approaches in Hypertension Management","authors":"J. Kitt, R. Fox, K. Tucker","doi":"10.29245/2578-3025/2020/1.1186","DOIUrl":"https://doi.org/10.29245/2578-3025/2020/1.1186","url":null,"abstract":"Hypertension is a key risk factor for cardiovascular disease. Globally, approximately a third of people with hypertension remain undiagnosed, and of those diagnosed, about half are not taking antihypertensive medication. The World Health Organization has estimated that globally hypertension directly or indirectly causes the deaths of at least nine million people every year. There is a trend towards self-monitoring of blood pressure (BP), where patients are empowered to be involved in hypertension screening and diagnosis. Novel technology, including smartphones and Blue-tooth® enabled telemonitoring, are new tools that are likely to be increasingly important in hypertension management. Several studies have shown the benefit of self-monitoring of BP coupled with co-interventions (such as telemonitoring) in improving BP management. However, these new technologies must be properly assessed and clinically validated prior to widespread implementation in the general population, or within special groups. In this mini-review, we examine how technology might improve the detection and management of hypertension.","PeriodicalId":93019,"journal":{"name":"Journal of cardiology and cardiovascular sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43446229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Stented Porcine and Pericardial Bioprostheses - A historical review 猪支架和心包生物假体-历史回顾
Journal of cardiology and cardiovascular sciences Pub Date : 2019-10-01 DOI: 10.29245/2578-3025/2019/5.1179
A. Martino, G. Falcetta, A. Milano, U. Bortolotti
{"title":"Stented Porcine and Pericardial Bioprostheses - A historical review","authors":"A. Martino, G. Falcetta, A. Milano, U. Bortolotti","doi":"10.29245/2578-3025/2019/5.1179","DOIUrl":"https://doi.org/10.29245/2578-3025/2019/5.1179","url":null,"abstract":"Stented bioprostheses have been extensively used clinically to replace diseased cardiac valves with the clear advantage over mechanical prostheses of avoiding the use of chronic anticoagulation in most cases. During the past five decades, however, based on clinical and pathological experience, tissue calcification and cusp tears were identified as the main determinants of failure of porcine and pericardial bioprostheses, respectively. Tissue treatments to mitigate dystrophic calcification together with structural modifications in valve design have produced a current generation of bioprosthetic valves which show excellent overall performance and considerably increased durability when compared with old models. Further ongoing research aims to provide even more durable bioprostheses in order to allow reduction of the age threshold for implantation also in younger subjects, helping to contrast effectively the rapidly expanding role of catheter-based interventions.","PeriodicalId":93019,"journal":{"name":"Journal of cardiology and cardiovascular sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46713344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long Non-Coding RNAs: Crucial Players of Cardiomyocyte Apoptosis 长非编码RNA：心肌细胞凋亡的关键因素
Journal of cardiology and cardiovascular sciences Pub Date : 2019-10-01 DOI: 10.29245/2578-3025/2019/5.1178
Xiatian Chen, Ziqian Liu, Zhe Li, Jinning Gao, Zhongjie Yu, Peifeng Li, L. Aung
{"title":"Long Non-Coding RNAs: Crucial Players of Cardiomyocyte Apoptosis","authors":"Xiatian Chen, Ziqian Liu, Zhe Li, Jinning Gao, Zhongjie Yu, Peifeng Li, L. Aung","doi":"10.29245/2578-3025/2019/5.1178","DOIUrl":"https://doi.org/10.29245/2578-3025/2019/5.1178","url":null,"abstract":"Long non-coding RNAs (lncRNAs) have gained more attention in recent years as a potential new regulator of nearly all biological regulation. LncRNAs are over 200 nucleotides in length, and it can interact with other non-coding RNAs or specific proteins to influence the gene expression. Cardiomyocyte apoptosis is associated with cardiovascular diseases. Accumulating studies have uncovered novel lncRNAs-mediated regulation of cardiovascular diseases; however, the knowledge of the mechanisms by how to act is still limited. This review highlights the role of lncRNAs involved in cardiomyocyte apoptosis with a focus on the regulatory axis. These examples may provide helpful insights on how lncRNAs interfere with cardiomyocyte apoptosis.","PeriodicalId":93019,"journal":{"name":"Journal of cardiology and cardiovascular sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43576299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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