SepsisPub Date : 2001-05-01DOI: 10.1023/A:1011402820464
M. Leone, F. Antonini, Claude D Martin
{"title":"Maintenance of Blood Pressure is Essential","authors":"M. Leone, F. Antonini, Claude D Martin","doi":"10.1023/A:1011402820464","DOIUrl":"https://doi.org/10.1023/A:1011402820464","url":null,"abstract":"","PeriodicalId":92956,"journal":{"name":"Sepsis","volume":"4 1","pages":"125-134"},"PeriodicalIF":0.0,"publicationDate":"2001-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/A:1011402820464","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57122872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
SepsisPub Date : 2001-05-01DOI: 10.1023/A:1011498619555
J. Preiser
{"title":"Role of Nitric Oxide in Cardiovascular Alterations","authors":"J. Preiser","doi":"10.1023/A:1011498619555","DOIUrl":"https://doi.org/10.1023/A:1011498619555","url":null,"abstract":"","PeriodicalId":92956,"journal":{"name":"Sepsis","volume":"4 1","pages":"99-109"},"PeriodicalIF":0.0,"publicationDate":"2001-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/A:1011498619555","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57130008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
SepsisPub Date : 2001-05-01DOI: 10.1023/A:1011406921372
M. Pinsky
{"title":"Both Perfusion Pressure and Flow Are Essential for Adequate Resuscitation","authors":"M. Pinsky","doi":"10.1023/A:1011406921372","DOIUrl":"https://doi.org/10.1023/A:1011406921372","url":null,"abstract":"","PeriodicalId":92956,"journal":{"name":"Sepsis","volume":"4 1","pages":"143-146"},"PeriodicalIF":0.0,"publicationDate":"2001-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/A:1011406921372","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57123276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
SepsisPub Date : 2001-05-01DOI: 10.1023/A:1011458922281
D. De Backer, J. Creteur, J. Vincent
{"title":"How Vasoactive Agents May Influence Regional Blood Flow","authors":"D. De Backer, J. Creteur, J. Vincent","doi":"10.1023/A:1011458922281","DOIUrl":"https://doi.org/10.1023/A:1011458922281","url":null,"abstract":"","PeriodicalId":92956,"journal":{"name":"Sepsis","volume":"4 1","pages":"147-158"},"PeriodicalIF":0.0,"publicationDate":"2001-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/A:1011458922281","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57127060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
SepsisPub Date : 2001-05-01DOI: 10.1023/A:1011454804534
D. Payen, A. C. Lucaszewicz
{"title":"Maintenance of Blood Flow Is Essential","authors":"D. Payen, A. C. Lucaszewicz","doi":"10.1023/A:1011454804534","DOIUrl":"https://doi.org/10.1023/A:1011454804534","url":null,"abstract":"","PeriodicalId":92956,"journal":{"name":"Sepsis","volume":"4 1","pages":"135-142"},"PeriodicalIF":0.0,"publicationDate":"2001-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/A:1011454804534","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57127153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
SepsisPub Date : 2001-05-01DOI: 10.1023/A:1011415123190
C. L. Holmes, J. Russell, K. Walley
{"title":"Sepsis: Is There Room for Vasopressin?","authors":"C. L. Holmes, J. Russell, K. Walley","doi":"10.1023/A:1011415123190","DOIUrl":"https://doi.org/10.1023/A:1011415123190","url":null,"abstract":"","PeriodicalId":92956,"journal":{"name":"Sepsis","volume":"4 1","pages":"169-175"},"PeriodicalIF":0.0,"publicationDate":"2001-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/A:1011415123190","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57123877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
SepsisPub Date : 2001-05-01DOI: 10.1023/A:1011446602717
J. Dhainaut, A. Cariou, I. Laurent
{"title":"Myocardial Dysfunction in Sepsis","authors":"J. Dhainaut, A. Cariou, I. Laurent","doi":"10.1023/A:1011446602717","DOIUrl":"https://doi.org/10.1023/A:1011446602717","url":null,"abstract":"","PeriodicalId":92956,"journal":{"name":"Sepsis","volume":"48 1","pages":"89-97"},"PeriodicalIF":0.0,"publicationDate":"2001-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/A:1011446602717","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57126260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
SepsisPub Date : 2001-01-01DOI: 10.1023/A:1013222407924
Jean-Daniel Chiche, Shidasp Siami, Jean-FrançDois Dhainaut, Jean-Paul Mira
{"title":"Cytokine Polymorphisms and Susceptibility to Severe Infectious Diseases.","authors":"Jean-Daniel Chiche, Shidasp Siami, Jean-FrançDois Dhainaut, Jean-Paul Mira","doi":"10.1023/A:1013222407924","DOIUrl":"https://doi.org/10.1023/A:1013222407924","url":null,"abstract":"<p><p>Cytokines are key regulators of the host response to infection, controlling the inflammatory reaction which is an essential component of the defense mechanisms. The major importance of these proteins in the pathogenesis and outcome of infectious diseases has been clearly demonstrated. In humans, there is increasing evidence that the host's cytokine response is genetically determined and that the genetic variability of cytokines underlies the complexity of interindividual differences in the immune response to micro organism invasions. We review the influence of host cytokine gene on the susceptibility to and the severity of parasitic, bacterial and viral infections. Proinflammatory cytokine polymorphisms are discussed in detail because of their importance in the course of severe infections such as meningococcal disease, cerebral malaria and septic shock. Genetic variants of the IL-10 gene, an antiinflammatory cytokine appear to be responsible for an uncontrolled and intense CARS and may have also dramatic consequences as an overwhelming inflammatory response. Our greater understanding of the genetic factors that influence mortality and morbidity of infectious diseases will permit identification of genomic markers which may be required for risk stratification of patients targeted for novel immunomodulatory treatments helping clinicians to select the most appropriate treatment options for their patients.</p>","PeriodicalId":92956,"journal":{"name":"Sepsis","volume":"4 3","pages":"209-215"},"PeriodicalIF":0.0,"publicationDate":"2001-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/A:1013222407924","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37832116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
SepsisPub Date : 2001-01-01DOI: 10.1023/A:1011450703625
M. Grocott, M. Mythen
{"title":"Fluid Administration in Septic Shock","authors":"M. Grocott, M. Mythen","doi":"10.1023/A:1011450703625","DOIUrl":"https://doi.org/10.1023/A:1011450703625","url":null,"abstract":"","PeriodicalId":92956,"journal":{"name":"Sepsis","volume":"4 1","pages":"111-124"},"PeriodicalIF":0.0,"publicationDate":"2001-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/A:1011450703625","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57126867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
SepsisPub Date : 2001-01-01DOI: 10.1023/A:1011463006351
T. van der Poll
{"title":"Effects of Catecholamines on the Inflammatory Response","authors":"T. van der Poll","doi":"10.1023/A:1011463006351","DOIUrl":"https://doi.org/10.1023/A:1011463006351","url":null,"abstract":"","PeriodicalId":92956,"journal":{"name":"Sepsis","volume":"69 1","pages":"159-167"},"PeriodicalIF":0.0,"publicationDate":"2001-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/A:1011463006351","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57127652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}