Journal of clinical cardiology and cardiovascular therapy最新文献_第8页

Role of 123-Iobenguane Myocardial Scintigraphy in Predicting Short Term Left Ventricular Functional Recovery and Indication to ICD Implantation after Coronary Revascularization: A Work Hypothesis 123-Iobenguane心肌显像在预测冠状动脉血运重建术后短期左心室功能恢复和ICD植入指征中的作用:一个工作假设

Journal of clinical cardiology and cardiovascular therapy Pub Date : 2015-08-10 DOI: 10.17554/j.issn.2309-6861.2015.02.80

Testa Marzia, Chauvie Stephane, Biggi Alberto, Terulla Alessandra, F. Mauro

{"title":"Role of 123-Iobenguane Myocardial Scintigraphy in Predicting Short Term Left Ventricular Functional Recovery and Indication to ICD Implantation after Coronary Revascularization: A Work Hypothesis","authors":"Testa Marzia, Chauvie Stephane, Biggi Alberto, Terulla Alessandra, F. Mauro","doi":"10.17554/j.issn.2309-6861.2015.02.80","DOIUrl":"https://doi.org/10.17554/j.issn.2309-6861.2015.02.80","url":null,"abstract":"AIM: 123I-Iobenguane myocardial scintigraphy (MIBG), which identifies sympathetic nervous system dysfunction, has been shown to be an effective predictor of sudden cardiac mortality in patient with congestive heart failure (CHF) and could be a useful instrument to early identify adverse clinical events. Methods: patients with CHF, a New York Heart Association classification (NYHA) of II or III and a left ventricular ejection fraction (LVEF) ≤ 35% were eligible for cardiac defibrillator (ICD) placement under current LVEF-based criteria in the guidelines. All patients listed for ICD underwent a MIBG before the implantation, in order to assess the prognostic value of an early cardiac MIBG to predict appropriate ICD indication. Results: 11 patients (100% males; age 65.1±8.9 years) with mean LVEF 29.1±4.9% entered the study. All patients had a coronary artery disease (CAD) treated by coronary artery bypass graft (CABG) in six cases, by a percutaneous coronary angioplasty (PTCA) in seven and both procedures in two patients. In all subjects the heart/mediastinum (H/M) ratio was calculated 35%. An ICD was implanted in six patients (54.5%). The sensitivity, specificity, postive and negative predictive value of an H/M ratio ≤ 1.25 at MIBG was calculated in 75%, 75%; 85,7%, 60%. Conclusion: MIBG might be a promising method for excluding a 3-month left ventricular functional recovery.","PeriodicalId":92802,"journal":{"name":"Journal of clinical cardiology and cardiovascular therapy","volume":"3 1","pages":"371-376"},"PeriodicalIF":0.0,"publicationDate":"2015-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75462097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Interplay of Aging, Aortic Stiffness and Blood Viscosity in Atherogenesis 衰老、主动脉硬度和血液粘度在动脉粥样硬化中的相互作用

Journal of clinical cardiology and cardiovascular therapy Pub Date : 2015-08-10 DOI: 10.17554/J.ISSN.2309-6861.2015.02.77

G. Sloop, J. Weidman, L. Shecterle, J. Cyr

引用次数: 11

Clinical Evaluation of Different Revascularization Strategies: Unlabelled Use 不同血运重建策略的临床评价:未标示使用

Journal of clinical cardiology and cardiovascular therapy Pub Date : 2015-08-10 DOI: 10.17554/j.issn.2309-6861.2015.02.82

M. Quezada-Feijoó, A. Mangas, Carmen Rodríguez, E. Segura, Carmen Toro-Fernandez, C. Gamero, David Gómez-Villarejo, R. Toro

{"title":"Clinical Evaluation of Different Revascularization Strategies: Unlabelled Use","authors":"M. Quezada-Feijoó, A. Mangas, Carmen Rodríguez, E. Segura, Carmen Toro-Fernandez, C. Gamero, David Gómez-Villarejo, R. Toro","doi":"10.17554/j.issn.2309-6861.2015.02.82","DOIUrl":"https://doi.org/10.17554/j.issn.2309-6861.2015.02.82","url":null,"abstract":"AIMS: Coronary diseases are the main cause of mortality in the West. Several factors may affect successful percutaneous revascularization, such as the type of stent used or the cardiovascular risk factors associated with the patient. The systolic function of the left ventricle has usually been disregarded in restenosis scores. Our aim is to evaluate restenosis while taking into account the kind of stent used and the systolic function of the left ventricle. METHODS: A prospective, observational and population study. A total of 209 patients with percutaneous revascularization were recruited between March 2011 and January 2013 and monitored every six months. Their clinical data was collected and transthoracic echocardiograms were performed. RESULTS: The average age was 67±11 years old, 64.6% were men. Regarding cardiovascular risk factors, 55.6% were diabetics, 84.2% had hypertension and 81.3% were dyslipemic. A combined revascularization strategy was more often used among the general population than in the diabetic subgroup. The diabetic patient subgroup received a larger number of drug-coated stents. The systolic function was present among 84% of the general population compared to 80% of the diabetic patient subgroup. Both the general population as well as the diabetic patient subgroup presented a significant decreased sistolic function of the left ventricle when the restenosis rate was greater (p<0.001 respectively). Similarly, we observe that there is a significant connection between the ejection fraction and the emergence of a new symptoms. CONCLUSION: The non-combined strategy was used more frequently in the diabetic population with the use of a superior drug-eluting stent Furthermore, systolic function evaluation stratifies the restenosis risk, especially in patients with a depressed ventricular function.","PeriodicalId":92802,"journal":{"name":"Journal of clinical cardiology and cardiovascular therapy","volume":"17 1","pages":"377-382"},"PeriodicalIF":0.0,"publicationDate":"2015-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78502422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Role of Myocardial Strain Imaging in Chemotherapy Related Cardiotoxicity 心肌应变显像在化疗相关心脏毒性中的作用

Journal of clinical cardiology and cardiovascular therapy Pub Date : 2015-08-10 DOI: 10.17554/j.issn.2309-6861.2015.02.76

A. Ogunsua, Amartya Kundu, Amir Y. Shaikh

引用次数: 2

Impaired Phenotype of Circulating Endothelial-Derived Microparticles: Novel Marker of Cardiovascular Risk 循环内皮衍生微粒的表型受损:心血管风险的新标志物

Journal of clinical cardiology and cardiovascular therapy Pub Date : 2015-08-10 DOI: 10.17554/J.ISSN.2309-6861.2015.02.78

A. Berezin

引用次数: 35

Morphological Alterations of the Heart and Blood Vessels from Tobacco Smoke: the Steps of the Damage 烟草烟雾对心脏和血管的形态学改变:损害的步骤

Journal of clinical cardiology and cardiovascular therapy Pub Date : 2015-08-10 DOI: 10.17554/j.issn.2309-6861.2015.02.81

A. Leone

{"title":"Morphological Alterations of the Heart and Blood Vessels from Tobacco Smoke: the Steps of the Damage","authors":"A. Leone","doi":"10.17554/j.issn.2309-6861.2015.02.81","DOIUrl":"https://doi.org/10.17554/j.issn.2309-6861.2015.02.81","url":null,"abstract":"Two cardiovascular structures are usually involved in the harm caused by cigarette smoke: myocardium and endothelium, which are mainly affected by carbon monoxide and nicotine. The harmful effects of smoking induce functional responses that eventually lead to morphological damage. With regard to the myocardium, three main steps have been well documented: myocardial alterations related to the hypoxia caused by increased concentrations in carboxyhemoglobin, reversible degenerative alterations of the cardiac muscle and irreversible myocardial necrosis. A typical experimental pattern due to smoking effects is the smoke cardiomyopathy. Endothelial dysfunction triggers a large number of responses, mainly consisting of blood and inflammatory cell migration and adhesion at the site of altered arterial wall,rupture of the muscular and elastic cells of the arterial wall and lipid infiltrates, which lead to atherosclerosis plaque. In addition, arteriosclerosis is the result of smoking on the resistance arteries. Evidence indicates that morphological alterations of the heart and blood vessels from smoking follow a well-defined way that allow us to tell the story of the cardiovascular alterations.","PeriodicalId":92802,"journal":{"name":"Journal of clinical cardiology and cardiovascular therapy","volume":"4 1","pages":"355-359"},"PeriodicalIF":0.0,"publicationDate":"2015-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73100955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

The Concept of Functional Foods and Functional Farming (4 F) in the Prevention of Cardiovascular Diseases: A Review of Goals from 18th World Congress of Clinical Nutrition 功能食品的概念和功能农业在心血管疾病预防中的作用——第18届世界临床营养大会目标综述

Journal of clinical cardiology and cardiovascular therapy Pub Date : 2015-08-10 DOI: 10.17554/j.issn.2309-6861.2015.02.75

Rb Singh, Toru Takahashi, S. Shastun, G. Elkilany, K. Hristova, A. Shehab, E. Onsaard, W. Phomkong, H. Chaves, Mukta Singh, Ratan K Srivastava, Munushi Srivastav, Rg Singh

引用次数: 10

A Massive Intake of Dabigatran: Case-Report and Short Review 大量摄入达比加群:病例报告和简短回顾

Journal of clinical cardiology and cardiovascular therapy Pub Date : 2015-06-10 DOI: 10.17554/j.issn.2309-6861.2014.02.588

P. Moronval, Lorraine Legeleux, S. Thomann, J. Schved, J. Davy, F. Roubille

{"title":"A Massive Intake of Dabigatran: Case-Report and Short Review","authors":"P. Moronval, Lorraine Legeleux, S. Thomann, J. Schved, J. Davy, F. Roubille","doi":"10.17554/j.issn.2309-6861.2014.02.588","DOIUrl":"https://doi.org/10.17554/j.issn.2309-6861.2014.02.588","url":null,"abstract":"Objective: The toxicity profile of new oral anticoagulants is well established and with their increasing use the adverse events are frequently encountered in clinical practice. Here, we describe the haemostatic abnormalities after a massive ingestion of dabigatran. Case summary: A 69-year-old woman was admitted for suicidal attempt after ingestion of 9 grams of dabigatran (60 x 150mg pills), associated with 400 mg of nebivolol, 600 mg of diazepam and 1.5 grams of amitriptyline. The patient did not suffer from any bleeding events. Only few voluntary massive intakes are until now reported. Discussion: There are only few cases reporting such a massive voluntary intake of dabigatran leading to biological disorders contrasting with no clinically significant intake. This surprising absence of bleeding events in our case could be at least partly explained by the poor gastrointestinal intake of the drug, a functional gastroparesis, and a theoretically self-limiting biological effect. Conclusion: As no antidote is currently available in routine use for dabigatran, a systematic collection of cases of dabigatran toxicity provide an insight into the clinical manifestations and potential therapeutic implications.","PeriodicalId":92802,"journal":{"name":"Journal of clinical cardiology and cardiovascular therapy","volume":"81 1","pages":"338-340"},"PeriodicalIF":0.0,"publicationDate":"2015-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86668156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Giant Ascending Aortic Aneurysm Mimicking Acute Coronary Syndrome 模拟急性冠状动脉综合征的巨大升主动脉瘤

Journal of clinical cardiology and cardiovascular therapy Pub Date : 2015-06-10 DOI: 10.17554/j.issn.2309-6861.2014.02.585

Mariama Akodad, T. Gandet, Y. Lounes, Corentin Curinier, F. Roubille

引用次数: 0

Systemic Lupus Erythematosus Presenting as Cardiac Tamponade Successfully Treated With High-Dose Steroid: A Case Report 大剂量类固醇成功治疗以心脏填塞为表现的系统性红斑狼疮1例

Journal of clinical cardiology and cardiovascular therapy Pub Date : 2015-06-10 DOI: 10.17554/j.issn.2309-6861.2014.02.586

Mariama Akodad, M. Berous, B. Lattuca, Sébastien Jugant, F. Roubille

引用次数: 0