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Infectious Disease Modeling 传染病建模
Systems medicine (New Rochelle, N.Y.) Pub Date : 2021-01-01 DOI: 10.1016/b978-0-12-801238-3.11471-0
Zhilan Feng, John W. Glasser
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引用次数: 0
Modeling Lymphocytes 建模的淋巴细胞
Systems medicine (New Rochelle, N.Y.) Pub Date : 2021-01-01 DOI: 10.1016/b978-0-12-801238-3.11608-3
J. Wittmann
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引用次数: 0
Overview: Data Generation Techniques: From Omics to Personalized Approaches and Clinical Care 概述:数据生成技术:从组学到个性化方法和临床护理
Systems medicine (New Rochelle, N.Y.) Pub Date : 2020-08-28 DOI: 10.1016/B978-0-12-801238-3.11708-8
D. Rozman
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引用次数: 1
Complex Networks in Health and Disease 健康和疾病中的复杂网络
Systems medicine (New Rochelle, N.Y.) Pub Date : 2020-08-28 DOI: 10.1016/B978-0-12-801238-3.11640-X
Loan Vulliard, Jörg Menche
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引用次数: 3
Recent Advances in Systems and Network Medicine: Meeting Report from the First International Conference in Systems and Network Medicine. 系统和网络医学的最新进展:第一届系统和网络医学国际会议会议报告。
Systems medicine (New Rochelle, N.Y.) Pub Date : 2020-02-26 eCollection Date: 2020-01-01 DOI: 10.1089/sysm.2020.0001
Emma Kurnat-Thoma, Ancha Baranova, Pat Baird, Elia Brodsky, Atul J Butte, Amrita K Cheema, Feixiong Cheng, Shuchismita Dutta, Christina Grant, James Giordano, Anke H Maitland-van der Zee, Douglas B Fridsma, Robert Jarrin, Maricel G Kann, Jonathon Keeney, Joseph Loscalzo, Guru Madhavan, Bradley A Maron, Dennis K McBride, Maeve McKean, Seong K Mun, James C Palmer, Bakul Patel, Kapil Parakh, Anne R Pariser, Christian Pristipino, Timothy R D J Radstake, Harsha K Rajasimha, William B Rouse, Damjana Rozman, Alif Saleh, Harald H H W Schmidt, Nikolaus Schultz, Tavpritesh Sethi, Edwin K Silverman, Jessica Skopac, Igor Svab, Sylvia Trujillo, James E Valentine, Dinesh Verma, Bruce J West, Sona Vasudevan
{"title":"Recent Advances in Systems and Network Medicine: Meeting Report from the First International Conference in Systems and Network Medicine.","authors":"Emma Kurnat-Thoma,&nbsp;Ancha Baranova,&nbsp;Pat Baird,&nbsp;Elia Brodsky,&nbsp;Atul J Butte,&nbsp;Amrita K Cheema,&nbsp;Feixiong Cheng,&nbsp;Shuchismita Dutta,&nbsp;Christina Grant,&nbsp;James Giordano,&nbsp;Anke H Maitland-van der Zee,&nbsp;Douglas B Fridsma,&nbsp;Robert Jarrin,&nbsp;Maricel G Kann,&nbsp;Jonathon Keeney,&nbsp;Joseph Loscalzo,&nbsp;Guru Madhavan,&nbsp;Bradley A Maron,&nbsp;Dennis K McBride,&nbsp;Maeve McKean,&nbsp;Seong K Mun,&nbsp;James C Palmer,&nbsp;Bakul Patel,&nbsp;Kapil Parakh,&nbsp;Anne R Pariser,&nbsp;Christian Pristipino,&nbsp;Timothy R D J Radstake,&nbsp;Harsha K Rajasimha,&nbsp;William B Rouse,&nbsp;Damjana Rozman,&nbsp;Alif Saleh,&nbsp;Harald H H W Schmidt,&nbsp;Nikolaus Schultz,&nbsp;Tavpritesh Sethi,&nbsp;Edwin K Silverman,&nbsp;Jessica Skopac,&nbsp;Igor Svab,&nbsp;Sylvia Trujillo,&nbsp;James E Valentine,&nbsp;Dinesh Verma,&nbsp;Bruce J West,&nbsp;Sona Vasudevan","doi":"10.1089/sysm.2020.0001","DOIUrl":"https://doi.org/10.1089/sysm.2020.0001","url":null,"abstract":"<p><p>The <i>First International Conference in Systems and Network Medicine</i> gathered together 200 global thought leaders, scientists, clinicians, academicians, industry and government experts, medical and graduate students, postdoctoral scholars and policymakers. Held at Georgetown University Conference Center in Washington D.C. on September 11-13, 2019, the event featured a day of pre-conference lectures and hands-on bioinformatic computational workshops followed by two days of deep and diverse scientific talks, panel discussions with eminent thought leaders, and scientific poster presentations. Topics ranged from: Systems and Network Medicine in Clinical Practice; the role of -omics technologies in Health Care; the role of Education and Ethics in Clinical Practice, Systems Thinking, and Rare Diseases; and the role of Artificial Intelligence in Medicine. The conference served as a unique nexus for interdisciplinary discovery and dialogue and fostered formation of new insights and possibilities for health care systems advances.</p>","PeriodicalId":92727,"journal":{"name":"Systems medicine (New Rochelle, N.Y.)","volume":"3 1","pages":"22-35"},"PeriodicalIF":0.0,"publicationDate":"2020-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/sysm.2020.0001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37783631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
PurifyR: An R Package for Highly Automated, Reproducible Variable Extraction and Standardization PurifyR:一个用于高度自动化，可重复的变量提取和标准化的R包
Systems medicine (New Rochelle, N.Y.) Pub Date : 2020-01-01 DOI: 10.1089/sysm.2019.0007
Wienand A. Omta, R. V. Heesbeen, I. Shen, A. Feelders, Matthieu J. S. Brinkhuis, D. Egan, M. Spruit
{"title":"PurifyR: An R Package for Highly Automated, Reproducible Variable Extraction and Standardization","authors":"Wienand A. Omta, R. V. Heesbeen, I. Shen, A. Feelders, Matthieu J. S. Brinkhuis, D. Egan, M. Spruit","doi":"10.1089/sysm.2019.0007","DOIUrl":"https://doi.org/10.1089/sysm.2019.0007","url":null,"abstract":"Life science experiments that employ automated technologies, such as high-content screens, frequently produce large datasets that require substantial amounts of preprocessing before analysis can be...","PeriodicalId":92727,"journal":{"name":"Systems medicine (New Rochelle, N.Y.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/sysm.2019.0007","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46371774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
De Novo and Supervised Endophenotyping Using Network-Guided Ensemble Learning 使用网络引导的集成学习从头开始和监督内表型
Systems medicine (New Rochelle, N.Y.) Pub Date : 2020-01-01 DOI: 10.1089/sysm.2019.0008
S. Larsen, Harald H. H. W. Schmidt, J. Baumbach
{"title":"De Novo and Supervised Endophenotyping Using Network-Guided Ensemble Learning","authors":"S. Larsen, Harald H. H. W. Schmidt, J. Baumbach","doi":"10.1089/sysm.2019.0008","DOIUrl":"https://doi.org/10.1089/sysm.2019.0008","url":null,"abstract":"Introduction: Precision medicine requires the accurate identification of genes and pathways that mechanistically define a disease phenotype. Modern omics may deliver this, but has until now yielded...","PeriodicalId":92727,"journal":{"name":"Systems medicine (New Rochelle, N.Y.)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/sysm.2019.0008","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41585318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
First International Conference in Systems and Network Medicine: Applications of Systems Science and Thinking to Biomedicine Georgetown University Medical Center Washington DC, USA September 11–13, 2019 第一届系统与网络医学国际会议：系统科学与思维在生物医学中的应用美国华盛顿乔治城大学医学中心2019年9月11日至13日
Systems medicine (New Rochelle, N.Y.) Pub Date : 2019-11-01 DOI: 10.1089/sysm.2019.29006.abstracts
{"title":"First International Conference in Systems and Network Medicine: Applications of Systems Science and Thinking to Biomedicine Georgetown University Medical Center Washington DC, USA September 11–13, 2019","authors":"","doi":"10.1089/sysm.2019.29006.abstracts","DOIUrl":"https://doi.org/10.1089/sysm.2019.29006.abstracts","url":null,"abstract":"","PeriodicalId":92727,"journal":{"name":"Systems medicine (New Rochelle, N.Y.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/sysm.2019.29006.abstracts","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46215653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epistasis Detection in Genome-Wide Screening for Complex Human Diseases in Structured Populations 结构人群中复杂人类疾病全基因组筛查中的鼻塞检测
Systems medicine (New Rochelle, N.Y.) Pub Date : 2019-09-27 DOI: 10.1089/sysm.2019.0003
Fentaw Abegaz, F. V. Lishout, J. M. John, Kridsadakorn Chiachoompu, Archana Bhardwaj, Elena S. Gusareva, Zhi Wei, H. Hakonarson, K. Steen
{"title":"Epistasis Detection in Genome-Wide Screening for Complex Human Diseases in Structured Populations","authors":"Fentaw Abegaz, F. V. Lishout, J. M. John, Kridsadakorn Chiachoompu, Archana Bhardwaj, Elena S. Gusareva, Zhi Wei, H. Hakonarson, K. Steen","doi":"10.1089/sysm.2019.0003","DOIUrl":"https://doi.org/10.1089/sysm.2019.0003","url":null,"abstract":"Abstract Over the years, a more prominent role has been given to gene–gene interaction (epistasis) detection, in view of precision medicine and the hunt for novel drug targets and biomarkers for co...","PeriodicalId":92727,"journal":{"name":"Systems medicine (New Rochelle, N.Y.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/sysm.2019.0003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42737840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
In Silico Clinical Studies on the Efficacy of Blue Light for Treating Psoriasis in Virtual Patients 蓝光治疗虚拟银屑病的临床研究
Systems medicine (New Rochelle, N.Y.) Pub Date : 2019-06-20 DOI: 10.1089/SYSM.2018.0007
Z. C. Felix Garza, J. Liebmann, M. Born, Paj Peter Hilbers, Nathan A. Riel
{"title":"In Silico Clinical Studies on the Efficacy of Blue Light for Treating Psoriasis in Virtual Patients","authors":"Z. C. Felix Garza, J. Liebmann, M. Born, Paj Peter Hilbers, Nathan A. Riel","doi":"10.1089/SYSM.2018.0007","DOIUrl":"https://doi.org/10.1089/SYSM.2018.0007","url":null,"abstract":"Abstract Background: Treatment of psoriasis with blue light reduces the symptoms of this skin condition. Despite the therapeutic effects of blue light, no clear guidelines have been established reg...","PeriodicalId":92727,"journal":{"name":"Systems medicine (New Rochelle, N.Y.)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/SYSM.2018.0007","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42123537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
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