Ravi Nahata, Michael J Mancino, Jeff Thostenson, Alison H Oliveto
{"title":"Survey of Treatment Preferences for Opioid Use Disorder.","authors":"Ravi Nahata, Michael J Mancino, Jeff Thostenson, Alison H Oliveto","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objectives: </strong>This study gathered preliminary information on the initial feasibility of using injection Naltrexone (NTX) therapy in opioid users.</p><p><strong>Methods: </strong>One hundred opioid users (36% female, 8% minorities, mean age 34.5±11.4 yrs.) undergoing a health screen to determine initial eligibility for an ongoing study completed the survey.</p><p><strong>Results: </strong>Of the 100 respondents, 26, 16, 16, 1 and 0 reported prior treatment episodes of opioid detoxification, buprenorphine (BUP), methadone (MTD), oral NTX and injection NTX, respectively. Ninety and 71% were interested in participating in a study involving oral and/or injection NTX treatment, respectively. Reasons for not wanting to try injection NTX included fear of needles (n=13), side effects (n=7), lack of pain relief (n=12) and cost (n=3). A significantly higher percentage of those interested in injection NTX had episodes of prior opioid agonist maintenance treatment relative to those uninterested (32.4% vs 10.3%; Chi<sup>2</sup>=5.2, p<0.03). Those preferring injection NTX therapy showed a higher level of interest in this therapy (3.08±1.01 vs 1.62±1.35; Rank Sum p<0.0001) and a lower degree of interest in BUP treatment (2.96±0.93 vs 3.38±0.90; Rank Sum p< 0.03) than those not preferring injection NTX.</p><p><strong>Conclusions: </strong>These preliminary results suggest that those with prior, failed experience with opioid agonist maintenance treatment are more likely to consider injection NTX therapy, suggesting it may be optimal as a second-line treatment for OUD.</p>","PeriodicalId":92660,"journal":{"name":"Jacobs journal of addiction and therapy","volume":"5 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530927/pdf/nihms-1012988.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37000453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}