Muhammed Bilaal Mirza, Jaspreet Virdee, Sonita Koshal
{"title":"Metastatic melanoma posing as periapical pathology: key features and learning points","authors":"Muhammed Bilaal Mirza, Jaspreet Virdee, Sonita Koshal","doi":"10.1038/s41415-025-8722-3","DOIUrl":"10.1038/s41415-025-8722-3","url":null,"abstract":"Malignant melanoma is a significant and rising health concern in the United Kingdom. Uncontrolled division of melanocytes caused by mutation underlies progression of the condition, which is associated with high mortality rates. General dental practitioners may serve as the sole regular point of contact with a healthcare professional for some patients and thus are uniquely positioned to identify and urgently refer patients presenting with suspicious symptoms or pathology. We present a case of metastatic malignant melanoma posing as odontogenic pathology, referred to the Oral Surgery Department at the Eastman Dental Hospital. We consider key diagnostic clues and red flags for melanoma indicating the need for urgent referral and management.","PeriodicalId":9229,"journal":{"name":"British Dental Journal","volume":"239 2","pages":"109-114"},"PeriodicalIF":2.0,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144695985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rajpal Tattar, Bruna Dias Cazvalho da Costa, Vitor C. M. Neves
{"title":"The interrelationship between periodontal disease and systemic health","authors":"Rajpal Tattar, Bruna Dias Cazvalho da Costa, Vitor C. M. Neves","doi":"10.1038/s41415-025-8642-2","DOIUrl":"10.1038/s41415-025-8642-2","url":null,"abstract":"Background Periodontal disease is a chronic inflammatory disease and has been linked to various systemic conditions. The chronic inflammation associated with periodontal disease could affect systemic health, while systemic conditions may also impact periodontal disease progression and severity. Aims This narrative review aims to examine the associations between periodontal disease and systemic diseases, with a focus on understanding the underlying mechanisms for each bodily system. Methods A comprehensive literature review was conducted to evaluate studies investigating periodontal disease as a potential factor influencing systemic health. Key topics included mechanisms of microbial translocation, inflammation and immune dysregulation across various systems. Results Periodontal disease has been associated with systemic inflammation and immune responses that may contribute to the development or exacerbation of systemic conditions. Specific pathways may involve bacterial translocation, cytokine production and immune hyperresponsiveness, all of which may affect systemic health. Discussion Managing periodontal health may reduce inflammatory markers associated with systemic diseases; although, evidence remains inconclusive for most conditions due to study heterogeneity. Conclusion Understanding the interactions between periodontal disease and systemic conditions could guide integrated healthcare strategies, emphasising periodontal care to improve systemic health outcomes. Further research is needed to clarify causal relationships and therapeutic benefits.","PeriodicalId":9229,"journal":{"name":"British Dental Journal","volume":"239 2","pages":"103-108"},"PeriodicalIF":2.0,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41415-025-8642-2.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144695965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"What to call those we care for","authors":"Philip Preshaw","doi":"10.1038/s41415-025-8993-8","DOIUrl":"10.1038/s41415-025-8993-8","url":null,"abstract":"","PeriodicalId":9229,"journal":{"name":"British Dental Journal","volume":"239 2","pages":"81-81"},"PeriodicalIF":2.0,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41415-025-8993-8.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144695943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
James W. Edwards, Birke Bogale, Jennifer E. Gallagher
{"title":"Correction to: Tackling geographic barriers to primary dental care (dental deserts): a systematic review","authors":"James W. Edwards, Birke Bogale, Jennifer E. Gallagher","doi":"10.1038/s41415-025-9001-z","DOIUrl":"10.1038/s41415-025-9001-z","url":null,"abstract":"","PeriodicalId":9229,"journal":{"name":"British Dental Journal","volume":"239 2","pages":"108-108"},"PeriodicalIF":2.0,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41415-025-9001-z.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144695958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Online toolkit to help parents of autistic children improve dental health","authors":"","doi":"10.1038/s41415-025-9026-3","DOIUrl":"10.1038/s41415-025-9026-3","url":null,"abstract":"","PeriodicalId":9229,"journal":{"name":"British Dental Journal","volume":"239 2","pages":"91-91"},"PeriodicalIF":2.0,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41415-025-9026-3.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144695951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Outstanding bond strength for a variety of applications","authors":"","doi":"10.1038/s41415-025-9038-z","DOIUrl":"10.1038/s41415-025-9038-z","url":null,"abstract":"","PeriodicalId":9229,"journal":{"name":"British Dental Journal","volume":"239 2","pages":"138-138"},"PeriodicalIF":2.0,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41415-025-9038-z.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144695952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}