Journal of nutrition & intermediary metabolism最新文献

{"title":"Impact of diurnal intermittent fasting during Ramadan on inflammatory and oxidative stress markers in healthy people: Systematic review and meta-analysis","authors":"Mo'ez Al-Islam E. Faris ,&nbsp;Haitham A. Jahrami ,&nbsp;Asma A. Obaideen ,&nbsp;Mohamed I. Madkour","doi":"10.1016/j.jnim.2018.11.005","DOIUrl":"10.1016/j.jnim.2018.11.005","url":null,"abstract":"<div><p>Studies on the impact of diurnal intermittent fasting during Ramadan on inflammatory and oxidative stress markers have been limited and yielded contradictory results. Therefore, we performed a systematic review and meta-analysis to comprehensively examine changes in inflammatory and oxidative stress markers in healthy people before and after Ramadan. Databases searched were: PubMed/MEDLINE, ProQuest Medical, Web of Science, Scopus, EBSCOhost, Science Direct, CINAHL, Cochrane, and Google Scholar. The reference lists of identified papers were also screened. There was no date restriction for papers. The studied inflammatory markers were: interleukin (IL)-1, IL-6, tumor necrosis factor-α (TNF-α), and C-reactive protein (CRP)/high sensitivity CRP (<em>hs</em>-CRP). The studied oxidative stress marker was malondialdehyde (MDA). We identified 12 studies (involving 311 participants) conducted in eight countries: Iran (K = 3), Turkey (K = 2), the Kingdom of Saudi Arabia (K = 2), Jordan (K = 1), the United Arab Emirates (K = 1), Denmark (K = 1), the Netherlands (K = 1), and Indonesia (K = 1). Diurnal fasting during Ramadan resulted in very small reductions in IL-1 (Hedge's g = 0.016), CRP/<em>hs</em>-CRP (Hedge's g = 0.119), and MDA (Hedge's g = 0.219), and small reductions in TNF-α (Hedge's g = 0.371) and IL-6 (Hedge's g = 0.407). These results suggest diurnal intermittent fasting during Ramadan provides some protection against elevated inflammatory and oxidative stress markers. Therefore, it may offer an opportunity to reduce low-grade systemic inflammation and oxidative stress, and subsequent adverse health effects in healthy people.</p></div>","PeriodicalId":91757,"journal":{"name":"Journal of nutrition & intermediary metabolism","volume":"15 ","pages":"Pages 18-26"},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jnim.2018.11.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44979464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Considerations for development of lactose-free food","authors":"Sheenam Suri ,&nbsp;Vikas Kumar ,&nbsp;Rasane Prasad ,&nbsp;Beenu Tanwar ,&nbsp;Ankit Goyal ,&nbsp;Sawinder Kaur ,&nbsp;Yogesh Gat ,&nbsp;Ashwani Kumar ,&nbsp;Jaspreet Kaur ,&nbsp;Digvijay Singh","doi":"10.1016/j.jnim.2018.11.003","DOIUrl":"10.1016/j.jnim.2018.11.003","url":null,"abstract":"<div><p>Lactose intolerance is a pathophysiological situation that occurs due to insufficiency of the “lactase” enzyme present in the jejunum. Ingestion of lactose containing products leads to alteration in intestinal digestion and colonic fermentation, leading to diarrhoea and other clinical discomforts. The articles reviewed were selected based on the following key descriptors such as lactose, lactose intolerance, lactose-free diet, non-dairy products, cost, nutritional composition and sensory attributes. Some lactose-free products made from the lactose hydrolysed milk or from the alternate milk sources possessing low nutritional and sensory quality are available in the market. These alternatives are high-priced comparative to the foods containing lactose. So, there is a strong urge to develop lactose-free products that are nutritionally adequate, economical and well accepted by the consumers with main focus on special considerations viz., finding an alternate non-lactose source, ensuring sensory and nutritional attributes, compliance with the concerned regulatory guidelines and economics. This unique comprehensive review will help the manufacturers in developing lactose-free products.</p></div>","PeriodicalId":91757,"journal":{"name":"Journal of nutrition & intermediary metabolism","volume":"15 ","pages":"Pages 27-34"},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jnim.2018.11.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45531198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors affecting microbial metabolism in a human fecal fermentation model to evaluate prebiotics","authors":"Shanthi G. Parkar ,&nbsp;Patricia Davis ,&nbsp;Tania M. Trower ,&nbsp;Duncan I. Hedderley ,&nbsp;Kevin H. Sutton ,&nbsp;John R. Ingram","doi":"10.1016/j.jnim.2018.12.003","DOIUrl":"10.1016/j.jnim.2018.12.003","url":null,"abstract":"<div><p><em>In vitro</em> fermentations using human fecal bacteria are an often used high through put strategy to evaluate the prebiotic potential of food ingredients. We investigated the influence of the substrate presented to fecal microbiota by monitoring the microbial short chain fatty acid production. We also examined the impact of cryopreserved glycerol stocks of feces on the performance of multiple batches of fermentations to examine the feasibility of using standardized inocula for multiple batches. Both composition and concentrations of bioactives (dietary fibre, polyphenols) were found to influence the metabolic capacity of human fecal microbiota. We also found that feces preserved at −80 °C provided a consistent and stable inoculum for performing batch fermentations for a duration of up to 3 years.</p></div>","PeriodicalId":91757,"journal":{"name":"Journal of nutrition & intermediary metabolism","volume":"15 ","pages":"Pages 55-57"},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jnim.2018.12.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46059798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anti-inflammatory and antioxidant feeding and supplementation may serve as adjuvants in women with fibromyalgia","authors":"Ismael San Mauro Martin ,&nbsp;Sara López Oliva ,&nbsp;Luis Collado Yurrita ,&nbsp;Sara Sanz Rojo ,&nbsp;Elena Garicano Vilar","doi":"10.1016/j.jnim.2018.11.002","DOIUrl":"10.1016/j.jnim.2018.11.002","url":null,"abstract":"<div><h3>Objectives</h3><p>Fibromyalgia syndrome is a chronic pain disorder of unknown causation associated with debilitating fatigue, unrefreshing sleep, cognitive and affective symptoms. There are no markers to monitor fibromyalgia progression and no cure. We aimed to analyze the effects of a turmeric-based supplement and a gluten-free, fermentable oligosaccharides, disaccharides, monosaccharides, and polyols and low histamine diet (<em>IGUBAC Diet</em>^®), with antioxidant and anti-inflammatory characteristics, in women with fibromyalgia.</p></div><div><h3>Methods</h3><p>a randomized, controlled, clinical trial, with 13 women (51.46 ± 8.04 years) diagnosed with fibromyalgia were assessed using the Chronic Pain Grade Scale, the Pain Catastrophizing Scale, the Fatigue Severity and Impact Scale and the Pittsburgh Sleep Quality Index. Anthropometric parameters, antioxidant and anti-inflammatory analysis and symptoms progression were measured before and after one month of treatment with turmeric supplement and <em>IGUBAC Diet</em>^®.</p></div><div><h3>Results</h3><p>No significant improvement was observed after one month of treatment as shown by Chronic Pain Grade-, Pain Catastrophizing-, Fatigue Severity- and Fatigue Impact Scales and Pittsburgh Sleep Quality Index, except for pain disturbances in work activities. Significant variations (p &lt; 0.05) were observed in the intensity of symptoms, except for nausea and vomiting.</p></div><div><h3>Conclusion</h3><p>Additional research is necessary to further elucidate the effects of a turmeric-based supplement with <em>IGUBAC Diet</em>^® in women with fibromyalgia. A multidisciplinary approach should be the goal of treatment for fibromyalgia.</p></div>","PeriodicalId":91757,"journal":{"name":"Journal of nutrition & intermediary metabolism","volume":"15 ","pages":"Pages 3-9"},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jnim.2018.11.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48096854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nutritional supplements for the prevention of diabetes mellitus and its complications","authors":"Sharon Yeung PharmD Candidate,&nbsp;Jane Soliternik PharmD Candidate,&nbsp;Nissa Mazzola PharmD, CDE","doi":"10.1016/j.jnim.2018.07.003","DOIUrl":"10.1016/j.jnim.2018.07.003","url":null,"abstract":"<div><p>Many patients commonly use nutritional supplements as an alternative or as an addition to their current medication regimen to prevent or treat diseases. One of these diseases, a leading cause of death in the United States, is diabetes mellitus and its complications [<span>1</span>]. For both type 1 and type 2 diabetes mellitus, studies have been conducted to test not only prescription medications, but also nutritional supplements that may a role in prevention of the progression of this disease and its associated complications. In this article, we will review the efficacy of nutritional supplements that have been used for the prevention of type 1 and type 2 diabetes mellitus and their main complications, including diabetic neuropathy, cardiovascular disease, and retinopathy.</p></div>","PeriodicalId":91757,"journal":{"name":"Journal of nutrition & intermediary metabolism","volume":"14 ","pages":"Pages 16-21"},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jnim.2018.07.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129237051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute metabolic responses to high fructose corn syrup ingestion in adolescents with overweight/obesity and diabetes","authors":"Mary E. Patterson ,&nbsp;Jennifer K. Yee,&nbsp;Paulin Wahjudi ,&nbsp;Catherine S. Mao,&nbsp;Wai-Nang P. Lee","doi":"10.1016/j.jnim.2018.08.004","DOIUrl":"10.1016/j.jnim.2018.08.004","url":null,"abstract":"<div><h3>Introduction</h3><p>Childhood obesity remains high in prevalence. Sugar-sweetened beverages containing high fructose corn syrup (HFCS) are a common source of excess calories among children and adolescents. Fructose metabolism differs from glucose metabolism, which may also differ from fructose + glucose metabolism in HFCS consumption. The purpose of this study was to determine the acute metabolic effects of HFCS ingestion after soft drink consumption in adolescents who are lean, have overweight/obesity, or have type 2 diabetes (T2DM).</p></div><div><h3>Methods</h3><p>Adolescents age 13–19 years were recruited into three groups: lean controls (n = 10), overweight/obese without diabetes (n = 10), or uncomplicated T2DM on metformin monotherapy (n = 5). After an overnight fast, subjects drank 12 ounces of soda containing HFCS. Blood samples were collected at time zero and every 15 min for 120 min to be analyzed for fructose, glucose, and insulin levels.</p></div><div><h3>Results</h3><p>Glucose and fructose concentrations rose quickly in the first 15 min. Fructose, which was very low at baseline, rose to 100–200 μM and remained higher than fasting concentrations even at 120 min in all groups. Glucose increased after soft drink consumption, with the highest concentrations among subjects with T2DM, but returned to baseline fasting levels at 120 min. Insulin levels increased 15 min after soft drink consumption and were the highest in the obese group. Lactate rose non-significantly in all subjects, with no differences between groups.</p></div><div><h3>Conclusion</h3><p>Among adolescents who are lean, overweight/obese, or have T2DM, drinking an HFCS-containing soft drink exposes the liver to fructose. Glucose excursions in T2DM may be impacted by exaggerated glucose cycling, or fructose metabolism to glucose. The context of fructose consumption with or without other carbohydrates is an important consideration in studies of fructose metabolism.</p></div>","PeriodicalId":91757,"journal":{"name":"Journal of nutrition & intermediary metabolism","volume":"14 ","pages":"Pages 1-7"},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jnim.2018.08.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37212812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nutritional supplements for diabetes","authors":"Melinda T. Coughlan","doi":"10.1016/j.jnim.2018.07.004","DOIUrl":"10.1016/j.jnim.2018.07.004","url":null,"abstract":"","PeriodicalId":91757,"journal":{"name":"Journal of nutrition & intermediary metabolism","volume":"14 ","pages":"Page 15"},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jnim.2018.07.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45935905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of omega-3 polyunsaturated fatty acid supplementation in the management of type 2 diabetes mellitus: A narrative review","authors":"C. Itsiopoulos ,&nbsp;W. Marx ,&nbsp;H.L. Mayr ,&nbsp;O.A. Tatucu-Babet ,&nbsp;S.R. Dash ,&nbsp;E.S. George ,&nbsp;G.L. Trakman ,&nbsp;J.T. Kelly ,&nbsp;C.J. Thomas ,&nbsp;L. Brazionis","doi":"10.1016/j.jnim.2018.02.002","DOIUrl":"10.1016/j.jnim.2018.02.002","url":null,"abstract":"<div><h3>Background</h3><p>Type 2 Diabetes Mellitus (T2DM) poses a significant health and financial burden to individuals and healthcare systems. Omega-3 polyunsaturated fatty acids (PUFA) possess numerous properties (e.g. anti-inflammatory, anti-thrombotic, anti-lipidemic) that may be beneficial in the management of T2DM and its complications.</p></div><div><h3>Methods</h3><p>In this narrative review, we discuss the potential mechanisms, clinical evidence-base, and practical considerations regarding the use of omega-3 PUFA supplementation for the management of glycaemic control and common comorbid conditions, including diabetic nephropathy and retinopathy, liver disease, cognition and mental health, and cardiometabolic disease.</p></div><div><h3>Results/conclusion</h3><p>Omega-3 PUFA supplementation is generally well-tolerated and does not appear to be contraindicated for patients on anticoagulant therapy; however, uncertainty persists regarding the purity and stability of commercial omega-3 PUFA products. Despite promising animal studies, the current clinical evidence for the use of omega-3 supplementation for the management of T2DM and associated conditions is both limited and conflicting. Results from existing clinical trials do not support the use of omega-3 PUFA for glycaemic control and there are limited studies in T2DM populations to support the use of omega-3 PUFAs for associated complications of diabetes. Possible contributors to the conflicting evidence base are study design issues, such as inadequate intervention period, sample size, omega 3 supplement dose, variations in the EPA to DHA ratio and clinical heterogeneity among diabetic populations.</p></div>","PeriodicalId":91757,"journal":{"name":"Journal of nutrition & intermediary metabolism","volume":"14 ","pages":"Pages 42-51"},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jnim.2018.02.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47136433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utility of curcumin for the treatment of diabetes mellitus: Evidence from preclinical and clinical studies","authors":"Susana Rivera-Mancía ,&nbsp;Joyce Trujillo ,&nbsp;José Pedraza Chaverri","doi":"10.1016/j.jnim.2018.05.001","DOIUrl":"10.1016/j.jnim.2018.05.001","url":null,"abstract":"<div><p>Turmeric or <em>Curcuma longa</em> is a natural product, whose medicinal properties have been extensively studied and a wide variety of therapeutic effects on several diseases such as neurodegenerative, hepatic and renal damage, cancer, and diabetes have been mainly attributed to its curcuminoid content. In the last decades, diabetes mellitus has become an alarming worldwide health issue, because of the increasing number of people suffering from the disease, as well as the devastating consequences for them. In this paper, we review the current basic and clinical evidence about the potential of curcumin/curcuminoids for the treatment of diabetes mellitus, mainly by its hypoglycemic, antioxidant, and anti-inflammatory properties. The activity of curcumin (or curcuminoids) as a hypoglycemic agent or just as an adjuvant to improve the metabolic profile and to ameliorate the associated complications of diabetes mellitus, such as diabetic nephropathy and cardiopathy is discussed. The interactions between curcumin and conventional antidiabetic drugs might be explored for the therapeutic management of diabetes mellitus.</p></div>","PeriodicalId":91757,"journal":{"name":"Journal of nutrition & intermediary metabolism","volume":"14 ","pages":"Pages 29-41"},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jnim.2018.05.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46221350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing the impact of oral iodine supplementation on whole body iodine store, thyroid autoimmunity and serum biochemistry profile in women of childbearing age","authors":"Saeideh Daei ,&nbsp;Sarmad Nourooz-Zadeh ,&nbsp;Farid Javandoust Gharehbagh ,&nbsp;Fatemeh Soltani ,&nbsp;Jaffar Nourooz-Zadeh","doi":"10.1016/j.jnim.2018.09.001","DOIUrl":"10.1016/j.jnim.2018.09.001","url":null,"abstract":"<div><h3>Background and aims</h3><p>Iodine supplementation is advised for women with compromised iodine intake in the preconception period. The purpose of this study was to evaluate the benefits and harms of a supplementary dose of iodine (150 μg/day) for 90 days in women of childbearing age.</p></div><div><h3>Materials and methods</h3><p>Non-pregnant females (n = 38; mean age: 24.1 ± 2.6 years; Range: 20–30) receiving a hall diet were enrolled. Measurements of urinary iodine excretion (UIC), thyroid autoimmunity biomarkers, serum clinical biochemistry profile and serum thyroglobulin were performed at baseline- and after iodine supplementation at 45- and 90 days, respectively.</p></div><div><h3>Results</h3><p>Median UICs (μg/L) at baseline and after iodine intervention were 110, 304 and 310, respectively. This coincided with reductions in thyroglobulin, triacylglycerol, HDL-C, LDL-C, LDH, ALP and CPK levels as well as the prevalence of participants with UIC &lt;150 μg/L. One new case of Tg-AB (+), a marked increase the titer of Tg-AB in one participant with TPO-AB (+)/Tg-AB (+) and two cases of increased thyroglobulin were observed after the iodine treatment.</p></div><div><h3>Conclusions</h3><p>This investigation indicates that in iodine sufficient regions, it might be difficult to maintain maternal iodine adequacy without iodine supplementation. The iodine supplementation was associated with improvement of atherogenic serum index, diminished levels of markers of cellular injury and a 42.1% drop in the prevalence of participants with maternal iodine deficiency. In instances, which screening of thyroid autoimmunity titers and thyroglobulin are not an option, we recommend the administration of iodine in lower dosages to prevent adverse and exaggerated autoimmune reactions.</p></div>","PeriodicalId":91757,"journal":{"name":"Journal of nutrition & intermediary metabolism","volume":"14 ","pages":"Pages 8-14"},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jnim.2018.09.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48881771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}