Journal of biomedical technology and research最新文献

Opportunities for Fluorochlorozirconate and Other Glass-Ceramic Detectors in Medical Imaging Devices. 氟氯锆酸盐和其他玻璃陶瓷探测器在医疗成像设备中的机会。

Journal of biomedical technology and research Pub Date : 2015-01-01 Epub Date: 2015-06-25 DOI: 10.19104/jbtr.2015.102

Jacqueline A Johnson, Russell L Leonard, A R Lubinsky, Stefan Schweizer

引用次数: 3

Archimedean Spiral Pairs with no Electrical Connections as a Passive Wireless Implantable Sensor 无电连接的阿基米德螺旋对作为无源无线植入式传感器

Journal of biomedical technology and research Pub Date : 2014-08-18 DOI: 10.19104/JBTR.2014.110

John F. Drazan, A. Gunko, Matthew K. Dion, Omar T. Abdoun, N. Cady, K. Connor, E. Ledet

{"title":"Archimedean Spiral Pairs with no Electrical Connections as a Passive Wireless Implantable Sensor","authors":"John F. Drazan, A. Gunko, Matthew K. Dion, Omar T. Abdoun, N. Cady, K. Connor, E. Ledet","doi":"10.19104/JBTR.2014.110","DOIUrl":"https://doi.org/10.19104/JBTR.2014.110","url":null,"abstract":"We have developed, modeled, fabricated, and tested a passive wireless sensor system that exhibits a linear frequency-displacement relationship. The displacement sensor is comprised of two anti-aligned Archimedean coils separated by an insulating dielectric layer. There are no electrical connections between the two coils and there are no onboard electronics. The two coils are inductively and capacitively coupled due to their close proximity. The sensor system is interrogated wirelessly by monitoring the return loss parameter from a vector network analyzer. The resonant frequency of the sensor is dependent on the displacement between the two coils. Due to changes in the inductive and capacitive coupling between the coils at different distances, the resonant frequency is modulated by coil separation. In a specified range, the frequency shift can be linearized with respect to coil separation. Batch fabrication techniques were used to fabricate copper coils for experimental testing with air as the dielectric. Through testing, we validated the performance of sensors as predicted within acceptable errors. Because of its simplicity, this displacement sensor has potential applications for in vivo sensing.","PeriodicalId":91529,"journal":{"name":"Journal of biomedical technology and research","volume":"48 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2014-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76197666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

Archimedean Spiral Pairs with no Electrical Connections as a Passive Wireless Implantable Sensor. 无电连接的阿基米德螺旋对作为无源无线植入式传感器。

Journal of biomedical technology and research Pub Date : 2014-01-01 Epub Date: 2014-08-18

John F Drazan, Aleksandra Gunko, Matthew Dion, Omar Abdoun, Nathaniel C Cady, Kenneth A Connor, Eric H Ledet

{"title":"Archimedean Spiral Pairs with no Electrical Connections as a Passive Wireless Implantable Sensor.","authors":"John F Drazan, Aleksandra Gunko, Matthew Dion, Omar Abdoun, Nathaniel C Cady, Kenneth A Connor, Eric H Ledet","doi":"","DOIUrl":"","url":null,"abstract":"We have developed, modeled, fabricated, and tested a passive wireless sensor system that exhibits a linear frequency-displacement relationship. The displacement sensor is comprised of two anti-aligned Archimedean coils separated by an insulating dielectric layer. There are no electrical connections between the two coils and there are no onboard electronics. The two coils are inductively and capacitively coupled due to their close proximity. The sensor system is interrogated wirelessly by monitoring the return loss parameter from a vector network analyzer. The resonant frequency of the sensor is dependent on the displacement between the two coils. Due to changes in the inductive and capacitive coupling between the coils at different distances, the resonant frequency is modulated by coil separation. In a specified range, the frequency shift can be linearized with respect to coil separation. Batch fabrication techniques were used to fabricate copper coils for experimental testing with air as the dielectric. Through testing, we validated the performance of sensors as predicted within acceptable errors. Because of its simplicity, this displacement sensor has potential applications for in vivo sensing.","PeriodicalId":91529,"journal":{"name":"Journal of biomedical technology and research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945132/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34679556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effects of Metal Ions on Heparin/Heparin Sulfate-Protein Interactions. 金属离子对肝素/硫酸肝素-蛋白相互作用的影响。

Journal of biomedical technology and research Pub Date : 2014-01-01 Epub Date: 2014-05-19 DOI: 10.19104/jbtr.2014.101

Fuming Zhang, Xinle Liang, Julie M Beaudet, Yujin Lee, Robert J Linhardt

{"title":"The Effects of Metal Ions on Heparin/Heparin Sulfate-Protein Interactions.","authors":"Fuming Zhang, Xinle Liang, Julie M Beaudet, Yujin Lee, Robert J Linhardt","doi":"10.19104/jbtr.2014.101","DOIUrl":"https://doi.org/10.19104/jbtr.2014.101","url":null,"abstract":"Heparin/heparin sulfate (HS) interacts with a number of proteins thereby playing an essential role in the regulation of many physiological processes. The understanding of heparin/HS-protein interactions at the molecular level is of fundamental importance to biology and will aid in the development of highly specific glycan-based therapeutic agents. The heparin-binding proteins (HBPs) interact with sulfated domains of heparin/HS chains primarily through ionic attraction between negatively charged groups in HS/heparin chains and basic amino acid residues within the protein. Reports in literature have been shown that heparin molecules have a high affinity for a wide range of metal ions. In the present study, we used surface plasmon resonance (SPR) to study the effects of metal ions (under physiological and non-physiological concentrations) on heparin/HS-protein interactions. The results showed that under non-physiological of metal ion concentration, different metal ions showed different effects on heparin binding to fibroblast growth factor-1 (FGF1) and interleakin-7 (IL7). While the effects of individual metal ion at physiological concentrations had little impact on protein binding, the mixed metal ions reduced the FGF1/heparin or IL7/heparin binding affinity, changing its binding profile.","PeriodicalId":91529,"journal":{"name":"Journal of biomedical technology and research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589159/pdf/nihms898956.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35393204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13

Mesenchymal Stem Cell Paracrine Factors in Vascular Repair and Regeneration. 血管修复与再生中的间充质干细胞旁分泌因子。

Journal of biomedical technology and research Pub Date : 2014-01-01 Epub Date: 2014-08-28 DOI: 10.19104/jbtr.2014.107

Divya Pankajakshan, Devendra K Agrawal

{"title":"Mesenchymal Stem Cell Paracrine Factors in Vascular Repair and Regeneration.","authors":"Divya Pankajakshan, Devendra K Agrawal","doi":"10.19104/jbtr.2014.107","DOIUrl":"https://doi.org/10.19104/jbtr.2014.107","url":null,"abstract":"Mesenchymal stem cell therapy show great optimism in the treatment of several diseases. MSCs are attractive candidates for cell therapy because of easy isolation, high expansion potential giving unlimited pool of transplantable cells, low immunogenicity, amenability to ex vivo genetic modification, and multipotency. The stem cells orchestrate the repair process by various mechanisms such as transdifferentiation, cell fusion, microvesicles or exosomes and most importantly by secreting paracrine factors. The MSCs release several angiogenic, mitogenic, anti-apoptotic, anti-inflammatory and anti-oxidative factors that play fundamental role in regulating tissue repair in various vascular and cardiac diseases. The therapeutic release of these factors by the cells can be enhanced by several strategies like genetic modification, physiological and pharmacological preconditioning, improved cell culture and selection methods, and biomaterial based approaches. The current review describes the impact of paracrine factors released by MSCs on vascular repair and regeneration in myocardial infarction, restenosis and peripheral artery disease, and the various strategies adopted to enhance the release of these paracrine factors to enhance organ function.","PeriodicalId":91529,"journal":{"name":"Journal of biomedical technology and research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589200/pdf/nihms898750.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35393207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 66