Advances in planar lipid bilayers and liposomes最新文献

筛选
英文 中文
Phenomenology based multiscale models as tools to understand cell membrane and organelle morphologies. 基于现象学的多尺度模型是理解细胞膜和细胞器形态的工具。
Advances in planar lipid bilayers and liposomes Pub Date : 2015-01-01 DOI: 10.1016/bs.adplan.2015.06.004
N Ramakrishnan, Ravi Radhakrishnan
{"title":"Phenomenology based multiscale models as tools to understand cell membrane and organelle morphologies.","authors":"N Ramakrishnan,&nbsp;Ravi Radhakrishnan","doi":"10.1016/bs.adplan.2015.06.004","DOIUrl":"https://doi.org/10.1016/bs.adplan.2015.06.004","url":null,"abstract":"<p><p>An intriguing question in cell biology is \"how do cells regulate their shape?\" It is commonly believed that the observed cellular morphologies are a result of the complex interaction among the lipid molecules (constituting the cell membrane), and with a number of other macromolecules, such as proteins. It is also believed that the common biophysical processes essential for the functioning of a cell also play an important role in cellular morphogenesis. At the cellular scale-where typical dimensions are in the order of micrometers-the effects arising from the molecular scale can either be modeled as equilibrium or non-equilibrium processes. In this chapter, we discuss the dynamically triangulated Monte Carlo technique to model and simulate membrane morphologies at the cellular scale, which in turn can be used to investigate several questions related to shape regulation in cells. In particular, we focus on two specific problems within the framework of isotropic and anisotropic elasticity theories: namely, (i) the origin of complex, physiologically relevant, membrane shapes due to the interaction of the membrane with curvature remodeling proteins, and (ii) the genesis of steady state cellular shapes due to the action of non-equilibrium forces that are generated by the fission and fusion of transport vesicles and by the binding and unbinding of proteins from the parent membrane.</p>","PeriodicalId":91442,"journal":{"name":"Advances in planar lipid bilayers and liposomes","volume":"22 ","pages":"129-175"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/bs.adplan.2015.06.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34411780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Liposomes: Methods and Protocols 脂质体:方法和方案
Advances in planar lipid bilayers and liposomes Pub Date : 2010-12-01 DOI: 10.1007/978-1-0716-2954-3
N. B. Chacra
{"title":"Liposomes: Methods and Protocols","authors":"N. B. Chacra","doi":"10.1007/978-1-0716-2954-3","DOIUrl":"https://doi.org/10.1007/978-1-0716-2954-3","url":null,"abstract":"","PeriodicalId":91442,"journal":{"name":"Advances in planar lipid bilayers and liposomes","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2010-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81612104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 25
The Cubic "Faces" of Biomembranes. 生物膜的立方“面”
Advances in planar lipid bilayers and liposomes Pub Date : 2010-01-01 Epub Date: 2010-10-21 DOI: 10.1016/B978-0-12-381266-7.00004-3
Zakaria A Almsherqi, Felix Margadant, Yuru Deng
{"title":"The Cubic \"Faces\" of Biomembranes.","authors":"Zakaria A Almsherqi,&nbsp;Felix Margadant,&nbsp;Yuru Deng","doi":"10.1016/B978-0-12-381266-7.00004-3","DOIUrl":"https://doi.org/10.1016/B978-0-12-381266-7.00004-3","url":null,"abstract":"<p><p>Biomembranes are traditionally viewed as flat phospholipid-bilayer sheets delineating the cell boundaries and dividing the cell into multiple subcellular organelles with specialized functions. However, biological membranes may also fold up into three-dimensional nanoperiodic arrangements, termed cubic membranes. This type of geometry is mathematically well described and extensively studied in lipidic cubic phase systems. This chapter will (1) summarize similarities and dissimilarities between cubic membranes and cubic phases; (2) provide an update on the experimental data describing the role of lipids, proteins and electrostatic charges on the biogenesis of cubic membranes; and (3) discuss their potential function in intracellular macromolecular transport and as optical filters, as well as potential practical applications such as gene delivery vehicles.</p>","PeriodicalId":91442,"journal":{"name":"Advances in planar lipid bilayers and liposomes","volume":"12 ","pages":"79-99"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/B978-0-12-381266-7.00004-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37842054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信