International journal of medicine最新文献_第2页

Homocystinuria presents with generalized tonic-clonic seizure and Broca's aphasia 同型半胱氨酸尿表现为全身性强直阵挛性发作和布洛卡失语

International journal of medicine Pub Date : 2022-08-27 DOI: 10.14419/ijm.v10i1.32096

Dr. Vivek R. Chaudhari, Dr. Jigar Mankad, Dr. Janki Lavingia, Dr. Manisha Panchal

{"title":"Homocystinuria presents with generalized tonic-clonic seizure and Broca's aphasia","authors":"Dr. Vivek R. Chaudhari, Dr. Jigar Mankad, Dr. Janki Lavingia, Dr. Manisha Panchal","doi":"10.14419/ijm.v10i1.32096","DOIUrl":"https://doi.org/10.14419/ijm.v10i1.32096","url":null,"abstract":"Homocystinuria follows an autosomal recessive pattern and transpires due to Cystathionine beta-synthase enzyme deficiency. This condition is associated with thrombotic and thromboembolic complications due to an increase in homocysteine and methionine levels in the plasma and urine. We present a case of an Indian adolescent boy who presented to us with generalized tonic clinic seizure and Broca's aphasia he was diagnosed as having homocystinuria type 1, and he responded well to treatment.Background: Stroke and seizure disorders in young adults have increased substantially and are a relatively common disorder that presents in the emergency department in all age groups. Secondary seizures are more common and manifest as a result of another underlying pathology. This case demonstrates the importance of considering rarer causes of thrombosis such as arterial thrombosis, even in younger patients, with no obvious risk factors or comorbidities. A detailed medical history and thorough investigations need to be taken to identify a potentially treatable underlying cause.Objective: To increase awareness about this rare etiology and help clinicians to have a higher level of suspicion to diagnose this condition and prevent future life-threatening complications in younger patients with thrombotic and thromboembolic events.Â Â Â","PeriodicalId":91290,"journal":{"name":"International journal of medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48959850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Coronavirus disease 2019 in an elderly patient who became severely ill despite antibody cocktail therapy but improved with lung-protective management: A case report 一名老年患者的2019冠状病毒病，尽管接受了抗体鸡尾酒治疗，但病情严重，但通过肺部保护管理得到了改善:一份病例报告

International journal of medicine Pub Date : 2022-06-07 DOI: 10.14419/ijm.v10i1.32070

Eriko Mitsutome, K. Une, Ryuichi Nakanuno

引用次数: 0

Knowledge, attitude and practices of mothers regarding immunization 母亲关于免疫接种的知识、态度和做法

International journal of medicine Pub Date : 2022-06-07 DOI: 10.14419/ijm.v10i1.32032

Shoaib Ali, Mubina Ifat, Javeria Amin, S. Jamil, Sahira Aaraj, Hamza Naeem, S. Javed, Shahida Nazir Siddiqui, Hamza Saeed Khokhar, Sarmad Zahoor

{"title":"Knowledge, attitude and practices of mothers regarding immunization","authors":"Shoaib Ali, Mubina Ifat, Javeria Amin, S. Jamil, Sahira Aaraj, Hamza Naeem, S. Javed, Shahida Nazir Siddiqui, Hamza Saeed Khokhar, Sarmad Zahoor","doi":"10.14419/ijm.v10i1.32032","DOIUrl":"https://doi.org/10.14419/ijm.v10i1.32032","url":null,"abstract":"Introduction: Immunization strengthens the defense mechanism of the body and offers protection against potential diseases. The rate of immunization is one of the best measures of public health management and quality. To increase the rate of immunization, parental decisions about vaccinations are very necessary. Parents' knowledge and attitude towards immunization influence the prevalence of infectious diseases. Moreover, vaccination is considered one of the most cost-effective public health tools to prevent infectious diseases.Objective: The objective of this study is to assess the frequency of adequate knowledge, positive attitude and good practices of mothers regarding immunization.Materials and Methods: It was a cross-sectional study which was conducted in The Children's Hospital & Child Health Institute, Lahore. A total of 125 children who met the selection criteria were enrolled. Parents were then questioned and validated by vaccination card status regarding various Expanded Immunization Policy (EPI) vaccinations and complete previous records. The awareness and attitude of mothers regarding vaccination was also considered that either they were aware of the vaccination status or not. All the data was collected and reported in the form of a questionnaire.Results: In this study93 mothers had a good understanding, 77 mothers had a good practice, and 66 mothers had a positive attitude towards immunization. Childsâ€™ gender, mothersâ€™ educational status, socio-economic status, good practice, and positive attitude had no significant impact on adequate knowledge about vaccination.Conclusion: It was concluded from this study that mothersâ€™ knowledge about immunization was adequate, however good practice and positive attitude were not up to the mark.Â Â ","PeriodicalId":91290,"journal":{"name":"International journal of medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45975607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thyrotoxic periodic paralysis mimicking hypokalemic periodic paralysis 类似低钾性周期性麻痹的甲状腺毒性周期性麻痹

International journal of medicine Pub Date : 2022-05-15 DOI: 10.14419/ijm.v10i1.32035

Dr. Vivek Chaudhari, Dr. Harshvardhansinh Chauhan, Dr. Manisha Panchal

{"title":"Thyrotoxic periodic paralysis mimicking hypokalemic periodic paralysis","authors":"Dr. Vivek Chaudhari, Dr. Harshvardhansinh Chauhan, Dr. Manisha Panchal","doi":"10.14419/ijm.v10i1.32035","DOIUrl":"https://doi.org/10.14419/ijm.v10i1.32035","url":null,"abstract":"Thyrotoxic periodic paralysis is a unique disorder that causes episodic proximal lower extremity muscle weakness in a patient who already has a hyperthyroid state and is not treated for the underlying disease state. The affected population mostly includes Asian in origin specifically the male gender (vs most thyroid disorder affects the women gender). Precipitating factors include in addition to a hyperthyroid state are strenuous exertion, a high-carbohydrate meal, and drugs like diuretics, insulin, high dose of steroids, antiretrovirals, and interferon therapy. Other genetic causes include the decreased activity of Kir2.6 mutation increased activity of Na+/K+ ATPase causing an intracellular shift of potassium that leads to hypokalaemia. The other challenging part for the physician is to differentiate it from Familial periodic paralysis an autosomal disorder seen in Caucasians and Western countries because both the disorders present similarly and differentiate between them by the presence of hyperthyroid state with hypokalaemia in Thyrotoxic periodic paralysis. The mortality is associated with respiratory paralysis hence the acute intervention includes giving nonselective beta-blockers followed by anti-thyroid medications. We present a case of an Indian adolescent who presented to us with lower muscle weakness with an underlying thyrotoxicosis state. This help physician with early diagnosis and appropriate treatment.Â Â Â ","PeriodicalId":91290,"journal":{"name":"International journal of medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42729479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ethylene glycol poisoning treated using combination of ethanol and haemodialysis therapy instead of fomepizole: a case report 乙醇与血液透析联合治疗乙二醇中毒1例

International journal of medicine Pub Date : 2021-09-08 DOI: 10.14419/IJM.V9I2.31706

K. Une, Y. Kishi, Yuichiro Hidaka, T. Esaki

引用次数: 0

Role of bilateral internal iliac artery ligation in controlling refractory post partum hemorrhage 双侧髂内动脉结扎术在控制难治性产后出血中的作用

International journal of medicine Pub Date : 2021-09-08 DOI: 10.14419/ijm.v9i2.31693

S. Jamil, Sara Munir, Javeria Amin, Shazia Nourin, Alia ., Zill E huma, Hamza Saeed Khokhar, Sultan Ul Moazzam, Muhammad Sohail Afzal

{"title":"Role of bilateral internal iliac artery ligation in controlling refractory post partum hemorrhage","authors":"S. Jamil, Sara Munir, Javeria Amin, Shazia Nourin, Alia ., Zill E huma, Hamza Saeed Khokhar, Sultan Ul Moazzam, Muhammad Sohail Afzal","doi":"10.14419/ijm.v9i2.31693","DOIUrl":"https://doi.org/10.14419/ijm.v9i2.31693","url":null,"abstract":"Background: Post Partum Hemorrhage (PPH) is a life threatening emergency that needs to be managed timely. Refractory PPH is treated surgically. Bilateral internal iliac artery ligation is one of the surgical procedures performed to control bleeding.Objective: We analyzed the effectiveness of Bilateral IIAL in controlling bleeding in PPHMethodology: It was a retrograde cross-sectional study conducted at Lady Aitchison hospital, Lahore from data during January 2018 to December 2020. After applying inclusion and exclusion criteria, data of patient including demographics, history, examination, ultrasound, procedure details and post-operative complications were recorded. All the data was analyzed using SPSS version 23.0.Results: All the patients (44) survived and success rate was 100 %. Uterine atony was present in 29 (65.9%) patients as a cause of PPH, placental abnormality, uterine rupture and coagulopathy in 7(15, 9), 4 (9.1%) and 4 (9.1%) patients respectively. 17 patients did not develop any complication. Most common Post-operative complication was wound infection (22.75%) followed by pneumonia (20.5%), paralytic ileus (9.1%) and DIC with renal failure (9.1%).Conclusion: Bilateral IIAL was found to be an effective and preferred life saving procedure, preserving fertility. ","PeriodicalId":91290,"journal":{"name":"International journal of medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49431761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Patient autonomy 病人自主权

International journal of medicine Pub Date : 2021-06-11 DOI: 10.14419/ijm.v9i1.31526

Muneerah Lbugami, Usamah El Alem

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Hepatitis E viral infection in pregnant ladies, a challenge for obstetricians and physicians 孕妇戊型肝炎病毒感染，对产科医生和内科医生的挑战

International journal of medicine Pub Date : 2021-05-01 DOI: 10.14419/ijm.v9i1.31468

S. Jamil, Hafiz Muhammad Sajid Jehangir, H. Naeem, Mahliqa Maqsud, Mehwish Ayyaz, Tayyaba Kanwal, Sarmad Zahoor, Muhammad Umer Mukhtar, Malik Muhammad Atif, Raza Manzoor Haideri

{"title":"Hepatitis E viral infection in pregnant ladies, a challenge for obstetricians and physicians","authors":"S. Jamil, Hafiz Muhammad Sajid Jehangir, H. Naeem, Mahliqa Maqsud, Mehwish Ayyaz, Tayyaba Kanwal, Sarmad Zahoor, Muhammad Umer Mukhtar, Malik Muhammad Atif, Raza Manzoor Haideri","doi":"10.14419/ijm.v9i1.31468","DOIUrl":"https://doi.org/10.14419/ijm.v9i1.31468","url":null,"abstract":"Background: Hepatitis E Virus (HEV) is the major cause of morbidity and mortality in pregnancy. The virus was detected about three decades ago. The incidence and severity during pregnancy vary widely around the world.Material & Methods: This observational retrospective study was conducted from March 2019 to February 2020 in Obstetrics & Gynecology Department of Lady Aitchison Hospital, Lahore. 70 pregnant women with hepatitis E were subjected to detailed history taking. The diagnosis was based on positive Hepatitis E IgM (Anti HEV IgM) antibody on laboratory test in current pregnancy in antenatal period up to 42 days post partum were included.Results: Out of 70 pregnant women with Hep E IgM+ve, 3 (4.3%) women had Obstetrical hysterectomy as complications, with mean age of 26.0 ± 4.69 years. The mean gestational age when infection occurred was 31.12 ± 5.18 weeks. Among all females 9 (13%) patients expired due to fulminant hepatic failure, 12 (17.14%) females gave birth via spontaneous vaginal delivery (SVD),17(24.2%) females gave birth via C-Section. 30 (42.8%) females were manage conservatively.Conclusion: Hepatitis E viral infection in pregnant females is a life threatening condition. The study showed that pregnant women with jaundice and hepatitis E virus infection had a high mortality rate during third trimester. Early diagnosis and management will help in the control of the disease and prevents its complications. ","PeriodicalId":91290,"journal":{"name":"International journal of medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46246352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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A Case of Abdominal Cocoon Syndrome: A Rare Cause of Small Bowel Obstruction At Aber Hospital in Northern Uganda 一例腹茧综合征：乌干达北部阿伯医院罕见的小肠梗阻原因

International journal of medicine Pub Date : 2021-05-01 DOI: 10.14419/ijm.v9i1.31508

Kizito Omona, Yasin Ssewanyana, Badru Ssekitooleko, Daniel Ongaro

{"title":"A Case of Abdominal Cocoon Syndrome: A Rare Cause of Small Bowel Obstruction At Aber Hospital in Northern Uganda","authors":"Kizito Omona, Yasin Ssewanyana, Badru Ssekitooleko, Daniel Ongaro","doi":"10.14419/ijm.v9i1.31508","DOIUrl":"https://doi.org/10.14419/ijm.v9i1.31508","url":null,"abstract":"Abdominal cocoon syndrome (ACS) is a rare cause of small bowel obstruction characterized by partial or complete encasement of small bowel loops in a thick fibro-collagenous sac. It poses diagnostic difficulties due to the non-specific nature of its presentation and thus in most cases, diagnosed incidentally at laparotomy.The researchers present a case of a 27-year old female Ugandan who presented to a rural hospital in Northern Uganda with complaints of central abdominal pain, failure to pass stool and bilious vomiting for three days. She also had feelings of a peri-umbilical mass. She had several episodes of related obstructive symptoms that would be self-limiting for a year. She had unremarkable past surgical, past medical and past gynecological history. Laboratory investigations were unremarkable.Preoperative diagnosis of small bowel intussusception was made basing on examination and ultrasonography report and the patient was managed operatively. At laparotomy, almost all the small bowel loops were found encased in a thick, whitish, fibrous membrane. There was also marked inter-loop adhesions. The membranous sac was incised and completely removed using both sharp and blunt dissection. Inter-loop adhesions were released solely by blunt dissection.The patient recovered postoperatively and was discharged on the seventh postoperative day. ","PeriodicalId":91290,"journal":{"name":"International journal of medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46048516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Loneliness and Cardiovascular Disease 孤独与心血管疾病

International journal of medicine Pub Date : 2021-04-21 DOI: 10.14419/ijm.v9i1.31462

S. Agarwal

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