Clujul medical (1957)最新文献

筛选
英文 中文
Psychological stress and breast cancer incidence: a systematic review. 心理压力与乳腺癌发病率:一项系统综述。
Clujul medical (1957) Pub Date : 2018-01-01 Epub Date: 2018-01-15 DOI: 10.15386/cjmed-924
Valentina-Fineta Chiriac, Adriana Baban, Dan L Dumitrascu
{"title":"Psychological stress and breast cancer incidence: a systematic review.","authors":"Valentina-Fineta Chiriac,&nbsp;Adriana Baban,&nbsp;Dan L Dumitrascu","doi":"10.15386/cjmed-924","DOIUrl":"https://doi.org/10.15386/cjmed-924","url":null,"abstract":"<p><strong>Objective: </strong>Breast cancer is the world's leading cause of cancer mortality in women. Stress is an imminent risk factor with a documented negative impact on neuro-endocrine and immune system. Numerous epidemiological studies have investigated the link between stress and cancer, reporting contradictory results from no association to a close causal link. The impact of the topic and the lack of conclusion compelled this systematic review.</p><p><strong>Methods: </strong>A systematic review was carried out, including all literature studies from 1966 to 2016, investigating the relationship between stress and the occurrence of breast cancer. Of the 1813 articles identified in the PubMed/Medline database, 52 were eligible and included in the analysis.</p><p><strong>Results: </strong>A number of 17 retrospective, 20 limited prospective and 15 prospective studies were analyzed. The number of patients exceeded 29,000, for a total number of more than 700.000 women recruited from hospital, screening cohorts or population registers. We identified 26 positive articles linking personal traits, stressful events and breast cancer, 18 negative articles that did not confirm their hypothesis and 8 articles that could not be classified. Facing heterogeneity, all possible misguiding factors such as: study design, information gathering, stress type, moment of exposure, individual susceptibility and personality, were discussed independently.</p><p><strong>Conclusions: </strong>Qualitative analysis of articles has revealed a possible association between stress and cancer, especially regarding stressful life events. In the absence of a meta-analysis and taking into account the methodological heterogeneity of the studies, the results are difficult to interpret and the role of chance is difficult to exclude.</p>","PeriodicalId":91233,"journal":{"name":"Clujul medical (1957)","volume":"91 1","pages":"18-26"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.15386/cjmed-924","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35828703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 63
Cancer risk associated with living at high altitude in Ecuadorian population from 2005 to 2014. 2005年至2014年厄瓜多尔人生活在高海拔地区的癌症风险
Clujul medical (1957) Pub Date : 2018-01-01 Epub Date: 2018-04-25 DOI: 10.15386/cjmed-932
David Israel Garrido, Santiago Moises Garrido
{"title":"Cancer risk associated with living at high altitude in Ecuadorian population from 2005 to 2014.","authors":"David Israel Garrido,&nbsp;Santiago Moises Garrido","doi":"10.15386/cjmed-932","DOIUrl":"https://doi.org/10.15386/cjmed-932","url":null,"abstract":"<p><strong>Background and aims: </strong>Cancer is a leading cause of death in Ecuador with high social and economic impact. This study aims to determinate the influence of living at a high altitude on the risk of developing or dying from cancer among the Ecuadorian population.</p><p><strong>Methods: </strong>This is an ecological and epidemiological analysis of cancer mortality and prevalence rates, based on national data from the Ecuadorian National Statistics and Census Institute, corresponding to the period between 2005 and 2014. This study includes the analysis of various types of cancer: gastric, colorectal, hepatic/bile duct, breast, uterine/cervix, and lymphatic/hematopoietic, using rates of mortality and prevalence. Additionally, the association between the risk of getting or dying from cancer and living at high altitude was investigated. This comparison was made between the population living in Highlands, over 2000 meters above sea level, and low-lying regions.</p><p><strong>Results: </strong>Living at high altitude was associated with a higher prevalence of cancer and also with a high mortality rate due to cancer. Risk of getting cancer was related to living at a higher altitude, as well as an increased risk of death by cancer: gastric (OR:1.204; p<0.001), colorectal (OR:1.421; p<0.001), hepatic/bile duct (OR:1.184; p<0.001), breast (OR:1.067; p=0.030), or lymphatic/hematopoietic neoplasms (OR:1.135; p<0.001).</p><p><strong>Conclusions: </strong>Through an epidemiologic analysis, the association between developing or dying from cancer and living at high altitude was obtained. However, further researche is needed to clarify these findings, something that could have a substantial impact on cancer prevention.</p>","PeriodicalId":91233,"journal":{"name":"Clujul medical (1957)","volume":"91 2","pages":"188-196"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/34/20/cm-91-188.PMC5958984.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36118315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 22
Observational study of the bisphosphonate-related osteonecrosis of jaws. 双膦酸盐相关颌骨骨坏死的观察研究。
Clujul medical (1957) Pub Date : 2018-01-01 Epub Date: 2018-04-25 DOI: 10.15386/cjmed-838
Andreea Elena Lungu, Madalina Anca Lazar, Andrada Tonea, Horatiu Rotaru, Rares Calin Roman, Mindra Eugenia Badea
{"title":"Observational study of the bisphosphonate-related osteonecrosis of jaws.","authors":"Andreea Elena Lungu,&nbsp;Madalina Anca Lazar,&nbsp;Andrada Tonea,&nbsp;Horatiu Rotaru,&nbsp;Rares Calin Roman,&nbsp;Mindra Eugenia Badea","doi":"10.15386/cjmed-838","DOIUrl":"https://doi.org/10.15386/cjmed-838","url":null,"abstract":"<p><strong>Introduction: </strong>The bisphosphonate-related osteonecrosis of the jaw was first referred to in 2003. Bisphosphonates action is focused on the osteoclasts. The drastic inhibition of the osteoclastic function is harmful for the jaws which are the only bones of the human skeleton in relative contact with the external environment. The adverse effects of the bisphosphonate-related therapy include the pathology for which they are prescribed, the atypical fractures in pathological bone.</p><p><strong>Method: </strong>The aim of this research was to analyze the risk factors and the treatment methods in case of osteonecrosis of the jaws. To achieve these goals, the author analyzed the observation sheets of the patients admitted to the Oral and Maxillofacial Surgery Clinic during the period 2010-2015. The inclusion criteria were as follows: treatment with bisphosphonates, current or previous; the lesions of the mucous gingiva of the maxillaries followed by exposed necrotic bone, older than 8 weeks, with no tendency of healing; specific radiological image showing extended osteolysis with diffuse outline or radiopacity surrounded by radio-transparence, representing the necrotic bone sequestered; no metastasis in the necrotic maxillary bone; patient with no medical background of cervical-facial radiations. The patients who met these criteria were admitted in the study after signing the informed consent. Afterwards, the information found in the notes of the observational sheet (anamnesis, general examination and the imagistic investigation, treatment, postoperative recovery, prescription, postoperative recommendations) were gathered and submitted for statistic analysis.</p><p><strong>Results: </strong>Of the 20 patients in total, 13 were women and 7 men, of ages ranging from 43 to 83. The most numerous cases were registered in the seventh age decade. All patients included in the study had lesions of the gingival maxillary mucosal areas with exposure of the subjacent necrotic bone. 60% of them were under intravenous treatment with zoledronic acid (Zometa®). A single patient was under oral treatment with bisphosphonates. 19 of these 20 patients developed osteonecrosis following a dental extraction while one case was due to the instability of the mandibular mobile prosthesis. 61% of the patients included in the study developed a necrotic process in the mandibular bone, 80% of the localizations were in the posterior area. As first intention, the choice of treatment was represented by local lavages with antiseptic solutions, general antibiotics and sequestrectomy. Of these patients, a third had relapsed and needed radical surgery treatment.</p><p><strong>Conclusions: </strong>Prevention of the bisphosphonate-related osteonecrosis of the jaw represents the best method of treatment. The development of bone sequesters damages the volume of the maxillary bone as such, reducing the chances for prosthetic functional rehabilitation of the dento-maxillary s","PeriodicalId":91233,"journal":{"name":"Clujul medical (1957)","volume":"91 2","pages":"209-215"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.15386/cjmed-838","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36118318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
Where are Romanian biomedical journals now and what does the future hold for them? A scientometric analysis. 罗马尼亚的生物医学期刊现在在哪里?它们的未来会怎样?科学计量分析。
Clujul medical (1957) Pub Date : 2018-01-01 Epub Date: 2018-01-15 DOI: 10.15386/cjmed-961
Dan L Dumitrascu
{"title":"Where are Romanian biomedical journals now and what does the future hold for them? A scientometric analysis.","authors":"Dan L Dumitrascu","doi":"10.15386/cjmed-961","DOIUrl":"https://doi.org/10.15386/cjmed-961","url":null,"abstract":"<p><strong>Background and aim: </strong>There is a competition between scientific journals in order to achieve leadership in their scientific field. There are several Romanian biomedical journals which are published in English and a smaller number in Romanian. We need a periodical analysis of their visibility and ranking according to scientometric measures.</p><p><strong>Methods: </strong>We searched all biomedical journals indexed on international data bases: Web of Science, PubMed, Scopus, Embase, Google Scholar. We analyzed their evaluation factors.</p><p><strong>Results: </strong>Several journals from Romania in the biomedical field are indexed in international databases. Their scientometric indexes are not high. The best journal was acquired by an international publisher and is no longer listed for Romania.</p><p><strong>Conclusions: </strong>There are several Romanian biomedical journals indexed in international databases that deserve periodical analysis. There is a need to improve their ranking.</p>","PeriodicalId":91233,"journal":{"name":"Clujul medical (1957)","volume":"91 1","pages":"75-78"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e1/98/cm-91-75.PMC5808272.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35828116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute pancreatitis during GLP-1 receptor agonist treatment. A case report. GLP-1受体激动剂治疗期间急性胰腺炎。一份病例报告。
Clujul medical (1957) Pub Date : 2018-01-01 Epub Date: 2018-01-15 DOI: 10.15386/cjmed-804
Bogdan Augustin Chis, Daniela Fodor
{"title":"Acute pancreatitis during GLP-1 receptor agonist treatment. A case report.","authors":"Bogdan Augustin Chis,&nbsp;Daniela Fodor","doi":"10.15386/cjmed-804","DOIUrl":"https://doi.org/10.15386/cjmed-804","url":null,"abstract":"<p><p>Glucagon-like peptide 1 receptor agonists (GLP-1RA) are the newest treatment for diabetes mellitus (DM). These drugs can down-regulate fasting glucose more than oral drugs and lead to more constant glucose levels compared to regular insulin. Acute pancreatitis is a serious condition that may have a fatal outcome. It has been shown that long term and high doses of GLP-1RA can cause pancreatic changes in animals, but no connection has been proven in humans. We present the case of a 67 years old man with DM treated with oral drugs for 10 years until 3 months before, when GLP-1RA was added. He presented progressive abdominal pain, vomiting, and increased level of serum lipase and amylase were found. Ultrasonography and computed tomography found pancreatic and peripancreatic fatty tissue inflammation (inflammation score 2, necrosis score 0). All the etiologies of acute pancreatitis (lithiasis, alcohol, autoimmune, or trauma) were excluded. After GLP-1RA cessation and supportive treatment the evolution was self-limited with full recovery within 5 days. We concluded that acute pancreatitis can be considered a side effect of the GLP-1 treatment.</p>","PeriodicalId":91233,"journal":{"name":"Clujul medical (1957)","volume":"91 1","pages":"117-119"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2d/07/cm-91-117.PMC5808258.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35828613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 15
Assessment of the quality of life and performance status in patients with oral submucous fibrosis in central India. 印度中部口腔黏膜下纤维化患者的生活质量和表现状况评估。
Clujul medical (1957) Pub Date : 2018-01-01 Epub Date: 2018-04-25 DOI: 10.15386/cjmed-806
Revant H Chole, Ranjitkumar Patil
{"title":"Assessment of the quality of life and performance status in patients with oral submucous fibrosis in central India.","authors":"Revant H Chole,&nbsp;Ranjitkumar Patil","doi":"10.15386/cjmed-806","DOIUrl":"https://doi.org/10.15386/cjmed-806","url":null,"abstract":"Background and aims Measuring quality of life in patients with oral submucous fibrosis is of utmost importance in assessing treatment outcomes. This study examined the impact of oral submucous fibrosis and its treatment on the quality of life and performance status of persons with oral submucous fibrosis. Methods Quality of life was measured in patients with oral submucous fibrosis using the European Organization for Research and Treatment of Cancer Quality of Life head and neck 35 Questionnaire (EORTC QLQ-C35); performance status was measured by Performance Status Scale for Head and Neck Cancer Patients (PSS-HN), at four points in time: baseline, one month, two months and three months after start of treatment. Results At the end of third month Group A and Group B showed 78% and 85% increase in mouth opening respectively. While the burning sensation of oral mucosa was decreased by 72% and 88% in group A and group B respectively (Z>1.96, P<0.05), there were significant differences in patients’ quality of life and functioning at three points in time (P < 0.05). Conclusion The European Organization for Research and Treatment of Cancer Quality of Life head and neck 35 Questionnaire and Performance Status Scale for Head and Neck Cancer Patients can be used successfully in potentially malignant disorders like oral submucous fibrosis. The results in this study will surely be a good guide forother studies on oral submucous fibrosis.","PeriodicalId":91233,"journal":{"name":"Clujul medical (1957)","volume":"91 2","pages":"203-208"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.15386/cjmed-806","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36118317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
The prevalence of long-term oral anticoagulation therapy in a cardiology center in Bucharest, Romania. 罗马尼亚布加勒斯特某心脏病中心长期口服抗凝治疗的流行情况。
Clujul medical (1957) Pub Date : 2018-01-01 Epub Date: 2018-01-15 DOI: 10.15386/cjmed-837
Adelina-Mihaela Sorescu, Tudor Enache, Suzana Guberna
{"title":"The prevalence of long-term oral anticoagulation therapy in a cardiology center in Bucharest, Romania.","authors":"Adelina-Mihaela Sorescu,&nbsp;Tudor Enache,&nbsp;Suzana Guberna","doi":"10.15386/cjmed-837","DOIUrl":"https://doi.org/10.15386/cjmed-837","url":null,"abstract":"<p><strong>Background and aims: </strong>Few studies discuss the prevalence of oral anticoagulation therapy (OAT) in clinical practice, despite their increasing use worldwide. In America, studies established that 20% to 80% of the patients with indication benefit from OAT. In Romania, there is no data regarding the utilization of oral anticoagulants. Thus, this study aims to determine the trends of OAT.</p><p><strong>Methods: </strong>We designed a cross-sectional study of the patients admitted to the Cardiology Department of the \"Bagdasar-Arseni\" Clinical Emergency Hospital, Bucharest, from the 1st of November 2016 until the 31st of January 2017. We considered OAT indications to be: atrial fibrillation/flutter (AF), pulmonary embolisms (PE), deep vein thrombosis (DVT), intramural or intracavitary thrombi and left ventricle aneurysms. Statistical analysis was performed with EpiInfo.</p><p><strong>Results: </strong>There were 783 patients admitted, 253 of these having an OAT indication (mean age 73.25 years, 53.75% female). Only 162 patients (64.03%) received it, either Vitamin K Antagonists (VKA) (78 patients, 48.14%), or Novel Oral Anticoagulants (NOAC) (84 patients, 51.85%). Reasons for not indicating such therapy included the hemorrhage risk (43.27%), the lack of adherence to the treatment (18.56%), the impossibility of INR monitoring (21.84%), the economic status (10.21%) and others (6.12%). 221 patients had AF (87.35%), 141 (63.8%) receiving OAT, VKA (67 patients, 47.51%), or NOAC (74 patients, 52.48%). 17 patients (6.71%) had a PE and/or DVT. 15 (88.23%) received OAT, AVK (11 patients, 73.33%), or NOAC (4 patients, 26.67%). 15 patients (5.92%) had other OAT indications (excepting AF or PE/DVT), 11 receiving OAT (73.33%), AVK (8 patients, 72.72%), or NOAC (3 patients, 27.27%).</p><p><strong>Conclusions: </strong>Our study determined that 64.03% of those with indication received OAT. Similar data is reported in the USA, suggesting an underuse of anticoagulants. The risk of hemorrhage, lack of adherence, the impossibility of INR monitoring or the economic status were some of the reasons for not recommending OAT.</p>","PeriodicalId":91233,"journal":{"name":"Clujul medical (1957)","volume":"91 1","pages":"37-41"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.15386/cjmed-837","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35828111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Detection of coronary artery disease by reduced features and extreme learning machine. 用简化特征和极限学习机检测冠状动脉疾病。
Clujul medical (1957) Pub Date : 2018-01-01 Epub Date: 2018-04-25 DOI: 10.15386/cjmed-882
Ram Sewak Singh, Barjinder Singh Saini, Ramesh Kumar Sunkaria
{"title":"Detection of coronary artery disease by reduced features and extreme learning machine.","authors":"Ram Sewak Singh,&nbsp;Barjinder Singh Saini,&nbsp;Ramesh Kumar Sunkaria","doi":"10.15386/cjmed-882","DOIUrl":"https://doi.org/10.15386/cjmed-882","url":null,"abstract":"<p><strong>Objective: </strong>Cardiovascular diseases generate the highest mortality in the globe population, mainly due to coronary artery disease (CAD) like arrhythmia, myocardial infarction and heart failure. Therefore, an early identification of CAD and diagnosis is essential. For this, we have proposed a new approach to detect the CAD patients using heart rate variability (HRV) signals. This approach is based on subspaces decomposition of HRV signals using multiscale wavelet packet (MSWP) transform and entropy features extracted from decomposed HRV signals. The detection performance was analyzed using Fisher ranking method, generalized discriminant analysis (GDA) and binary classifier as extreme learning machine (ELM). The ranking strategies designate rank to the available features extracted by entropy methods from decomposed heart rate variability (HRV) signals and organize them according to their clinical importance. The GDA diminishes the dimension of ranked features. In addition, it can enhance the classification accuracy by picking the best discerning of ranked features. The main advantage of ELM is that the hidden layer does not require tuning and it also has a fast rate of detection.</p><p><strong>Methodology: </strong>For the detection of CAD patients, the HRV data of healthy normal sinus rhythm (NSR) and CAD patients were obtained from a standard database. Self recorded data as normal sinus rhythm (Self_NSR) of healthy subjects were also used in this work. Initially, the HRV time-series was decomposed to 4 levels using MSWP transform. Sixty two features were extracted from decomposed HRV signals by non-linear methods for HRV analysis, fuzzy entropy (FZE) and Kraskov nearest neighbour entropy (K-NNE). Out of sixty-two features, 31 entropy features were extracted by FZE and 31 entropy features were extracted by K-NNE method. These features were selected since every feature has a different physical premise and in this manner concentrates and uses HRV signals information in an assorted technique. Out of 62 features, top ten features were selected, ranked by a ranking method called as Fisher score. The top ten features were applied to the proposed model, GDA with Gaussian or RBF kernal + ELM having hidden node as sigmoid or multiquadric. The GDA method transforms top ten features to only one feature and ELM has been used for classification.</p><p><strong>Results: </strong>Numerical experimentations were performed on the combination of datasets as NSR-CAD and Self_NSR- CAD subjects. The proposed approach has shown better performance using top ten ranked entropy features. The GDA with RBF kernel + ELM having hidden node as multiquadric method and GDA with Gaussian kernel + ELM having hidden node as sigmoid or multiquadric method achieved an approximate detection accuracy of 100% compared to ELM and linear discriminant analysis (LDA)+ELM for both datasets. The subspaces level-4 and level-3 decomposition of HRV signals by MSWP transform can","PeriodicalId":91233,"journal":{"name":"Clujul medical (1957)","volume":"91 2","pages":"166-175"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.15386/cjmed-882","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36118377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 31
Acral-acroma malignant melanoma. A clinical case report and review of literature. 肢端-肩峰恶性黑色素瘤。临床病例报告及文献复习。
Clujul medical (1957) Pub Date : 2018-01-01 Epub Date: 2018-01-15 DOI: 10.15386/cjmed-801
Corina-Maria Botici, Lăcrimioara Covaci, Claudia Judea-Pusta, Andrei Paşcalău
{"title":"Acral-acroma malignant melanoma. A clinical case report and review of literature.","authors":"Corina-Maria Botici,&nbsp;Lăcrimioara Covaci,&nbsp;Claudia Judea-Pusta,&nbsp;Andrei Paşcalău","doi":"10.15386/cjmed-801","DOIUrl":"https://doi.org/10.15386/cjmed-801","url":null,"abstract":"<p><strong>Objective: </strong>The main objective of this paper is to emphasize the importance of the early diagnosis of certainty in the cases of acral-acroma malignant melanoma in order to increase the survival rate.</p><p><strong>Method: </strong>The paper is a review of specialty literature and presents a clinical case of acral-acroma malignant melanoma. Clinical case: acral-acroma malignant melanoma with confirmed lymph node metastases and possibly secondary remote dissemination to the skin in a male patient aged 16 years. We conducted histo-pathological and immunohistochemical examinations of the collected tissue-fragments.</p><p><strong>Results: </strong>The results obtained from the histochemical and immunohisto-chemical examinations are presented, as well as the problems of differential diagnosis.</p><p><strong>Conclusion: </strong>The early diagnosis of certainty significantly increases the survival rate. Knowledge and awareness of the population on the use of preventive measures regarding the occurence of the acral-acroma malignant melanoma is therefore required.</p>","PeriodicalId":91233,"journal":{"name":"Clujul medical (1957)","volume":"91 1","pages":"112-116"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5f/2c/cm-91-112.PMC5808257.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35828611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Heritage of Stanisław Ostrowski - the only one medical doctor who became state Polish President - Patriae Semper Fidelis. 斯坦尼斯瓦夫-奥斯特洛夫斯基(Stanisław Ostrowski)的遗产--唯一一位成为波兰国家总统的医学博士--Patriae Semper Fidelis。
Clujul medical (1957) Pub Date : 2018-01-01 Epub Date: 2018-01-15 DOI: 10.15386/cjmed-883
Martyna Woltanowska, Piotr Woltanowski, Andrzej Wincewicz, Magdalena Woltanowska
{"title":"Heritage of Stanisław Ostrowski - the only one medical doctor who became state Polish President - Patriae Semper Fidelis.","authors":"Martyna Woltanowska, Piotr Woltanowski, Andrzej Wincewicz, Magdalena Woltanowska","doi":"10.15386/cjmed-883","DOIUrl":"10.15386/cjmed-883","url":null,"abstract":"<p><strong>Aim: </strong>Our purpose was to write a biography of Stanisław Ostrowski that would address in the first place the medical aspect of his professional life, with a comprehensive approach of others fields of his activity.</p><p><strong>Methods: </strong>We essentially grounded the paper on primary resources that were papers authored by Ostrowski including his scientific publications, memories, speeches as well as contemporaneous official documents that referred to Ostrowski. Second resources were also used to double check some data from primary resources and to place the biography of Stanisław Ostrowski in a proper background with special care to social, professional and political context. In this study, second resources comprised papers, that were prepared after the death of Stanisław Ostrowski.</p><p><strong>Results: </strong>Stanisław Ostrowski, MD was a meticulous military medical doctor with an academic engagement at the King John Casimir University of Lvov. In addition, he was an excellent organizer, who soon got involved in politics to serve the local community with essential projects in public health particularly anti-tuberculosis campaigns in Lvov district. His quiet and proficient nature made him an ideal statesman with incredible skills to reconcile social, national and political enemies. Ostrowski was elected a member of parliament three times. He also held the position of President of the city of Lvov until World War Two. During the war, he was imprisoned and deported to Siberia, Soviet Union, in years 1939-1941. Subsequently he fought against Nazi Germans in the Polish II Corps. Ostrowski survived the war providing medical service in the various military units. Afterwards, he ran his medical practice in the UK. Stanisław Ostrowski was the only dermatologist who became a state president. He held an office of state president of the Polish Republic on exile in London.</p><p><strong>Discussion and conclusion: </strong>His life is not a simple story, but a great lesson that provides clear guidelines how to find a stable ground for lifetime being a medical doctor in the turbulent times of the 20th century even during wartime.</p>","PeriodicalId":91233,"journal":{"name":"Clujul medical (1957)","volume":"91 1","pages":"129-142"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/07/f6/cm-91-129.PMC5808261.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35828614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信