Borneo Journal of Pharmacy最新文献_第10页

Anti-Inflammatory and Analgesic Activity of Musa balbisiana Peels In Vivo 麝香果皮的体内抗炎镇痛作用

Borneo Journal of Pharmacy Pub Date : 2022-05-31 DOI: 10.33084/bjop.v5i2.3169

N. M. D. Sandhiutami, S. Khairani, R. S. Dewi, Zainur Rahman Hakim, Anita Rahmi Pradani

{"title":"Anti-Inflammatory and Analgesic Activity of Musa balbisiana Peels In Vivo","authors":"N. M. D. Sandhiutami, S. Khairani, R. S. Dewi, Zainur Rahman Hakim, Anita Rahmi Pradani","doi":"10.33084/bjop.v5i2.3169","DOIUrl":"https://doi.org/10.33084/bjop.v5i2.3169","url":null,"abstract":"Musa balbisiana Peels (MBP) contains high levels of flavonoids, alkaloids, tannins, saponins, and triterpenoids. Flavonoids function to slow down the inflammatory process by inhibiting the arachidonic acid, forming prostaglandins, and releasing histamine. This study aimed to examine the anti-inflammatory and analgesic effects of MBP decoction. This study used the Winter method for anti-inflammatory assay by induction of carrageenan on the soles of rat's feet and Sigmund's method for analgesic assay with intraperitoneal induction of acetic acid in mice. Group I as a negative control, group II as a positive control with diclofenac sodium, group III as a low dose (200 mg/kg BW of MBP), group IV as a medium dose (400 mg/kg BW of MBP), and group V as a high dose (800 mg/kg BW of MBP decoction). The percentage of inhibition in the anti-inflammatory test in rats for groups II, III, IV, and V was 34.43%, 17.68%, 25.53%, and 25.4%, and the percentage of effectiveness for the anti-inflammatory test, respectively, was 51.35%, 74.15%, and 74.01%. The results of the percentage inhibition of the analgesic test in mice for groups II, III, IV, and V were 55.25%, 38.52%, 44.53%, and 49.31%, and the percentage of effectiveness for the analgesic test, respectively, followed by 69.71%, 80.59%, and 89.24%. Based on the results, it can be concluded that the decoction of the MBP has an anti-inflammatory and analgesic effect.","PeriodicalId":9118,"journal":{"name":"Borneo Journal of Pharmacy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89396441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Effect of Drug Information Service on Clinical Outcome of Patients with Type 2 Diabetes Mellitus in Padang, Indonesia 药物信息服务对印尼巴东地区2型糖尿病患者临床预后的影响

Borneo Journal of Pharmacy Pub Date : 2022-05-31 DOI: 10.33084/bjop.v5i2.3301

L. Lailaturrahmi, Fuji Araswati, A. Armenia, Rahmi Yosmar

{"title":"Effect of Drug Information Service on Clinical Outcome of Patients with Type 2 Diabetes Mellitus in Padang, Indonesia","authors":"L. Lailaturrahmi, Fuji Araswati, A. Armenia, Rahmi Yosmar","doi":"10.33084/bjop.v5i2.3301","DOIUrl":"https://doi.org/10.33084/bjop.v5i2.3301","url":null,"abstract":"Type 2 diabetes mellitus (T2DM) has been a health burden worldwide, including Indonesia. However, T2DM therapy needs a long and complex process, which patients often do not favor, thus making them does not take medications as instructed and negatively affecting clinical outcomes. This study aimed to understand the effect of Drug Information Service provision on the clinical outcome of T2DM patients. This quasi-experimental study was conducted using one group pre-post-test design. As the clinical outcome, the fasting blood glucose levels were measured before and after the intervention. A drug information service was provided through direct explanation to the patients. Sociodemographic data were analyzed descriptively. The difference in fasting blood glucose before and after the intervention was assessed using Wilcoxon signed-rank test. Forty patients participated in this study. Most participants are female (N=34; 85%) and receive two-drugs combination therapy of metformin and sulfonylureas (N=32; 77.5%). Although there is a decrease in mean fasting blood glucose level after intervention (174.92±59.561 vs. 184.20±49.768), there is no significant difference between fasting blood glucose levels pre-intervention and post-intervention (p>0.05). It is concluded that despite the noticeable decline of blood glucose level after drug information service, its effect on blood glucose control is not significant.","PeriodicalId":9118,"journal":{"name":"Borneo Journal of Pharmacy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77269462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Optimization of Quercetin Gel Formulation using Factorial Design Method and Antibacterial Test against Propionibacterium acnes 用因子设计法优化槲皮素凝胶配方及对痤疮丙酸杆菌的抑菌试验

Borneo Journal of Pharmacy Pub Date : 2022-05-31 DOI: 10.33084/bjop.v5i2.3321

M. Chandra, I. Kuncahyo, A. Indrayati

{"title":"Optimization of Quercetin Gel Formulation using Factorial Design Method and Antibacterial Test against Propionibacterium acnes","authors":"M. Chandra, I. Kuncahyo, A. Indrayati","doi":"10.33084/bjop.v5i2.3321","DOIUrl":"https://doi.org/10.33084/bjop.v5i2.3321","url":null,"abstract":"Quercetin is a flavonoid from a group of polyphenolic flavonoid compounds. Quercetin can be used as an alternative to acne treatment, predominantly triggered by Propionibacterium acnes. This study aimed to determine the effect and proportion of carbopol 940, propylene glycol, and glycerin on the physical quality of quercetin gel, the ability of the optimum formula in an antibacterial test, and its diffusion using Franz diffusion. This study uses the factorial design method for formula optimization. Optimization was carried out with the parameters of the physical quality of the gel tested, including viscosity, dispersibility, antibacterial, and Franz diffusion. The combination of carbopol 940, glycerin, and propylene glycol affected the physical quality test of quercetin gel, carbopol and glycerin significantly affected viscosity. In contrast, glycerin and propylene glycol significantly affected Franz's dispersion, antibacterial, and diffusion properties. The optimum proportion of the combination of carbopol 940, glycerin, and propylene glycol in the manufacture of quercetin gel using the factorial design method obtained a concentration of carbopol 940 of 0.5%, glycerin of 15%, and propylene glycol of 10%. The optimum formula ability in the antibacterial test was 22.20 mm, and the cumulative percent of quercetin penetrated was 97.91%.","PeriodicalId":9118,"journal":{"name":"Borneo Journal of Pharmacy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79241289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Trends of Influenza’s Symptoms Drug Search Terms in Indonesian-Language using Google Trends in the Covid-19 Pandemic Covid-19大流行期间使用谷歌趋势的流感症状趋势药物搜索词(印尼语

Borneo Journal of Pharmacy Pub Date : 2022-05-31 DOI: 10.33084/bjop.v5i2.2997

N. Syifa, Nurul Purborini

引用次数: 0

Cover, Content, and Editorial Note from Borneo J Pharm Vol. 5 No. 2 May 2022 封面、内容和编辑注释来自Borneo J Pharm第5卷第2期，2022年5月

Borneo Journal of Pharmacy Pub Date : 2022-05-31 DOI: 10.33084/bjop.v5i2.3762

C. E. O. Borneo J Pharm

{"title":"Cover, Content, and Editorial Note from Borneo J Pharm Vol. 5 No. 2 May 2022","authors":"C. E. O. Borneo J Pharm","doi":"10.33084/bjop.v5i2.3762","DOIUrl":"https://doi.org/10.33084/bjop.v5i2.3762","url":null,"abstract":"Assalamu’alaikum Wr. Wb. \u0000Alhamdulillahirabbil ‘alamin. The next edition of the Borneo Journal of Pharmacy (Borneo J Pharm) has been published in May 2022. This edition contains ten articles consisting of Pharmacology-Toxicology, Pharmacognosy-Phytochemistry, Pharmaceutical, Microbiology Pharmacy, Natural Product Development, and Clinical-Community Pharmacy. This edition includes writings from four countries, including India, Indonesia, Nigeria, and Sri Lanka. The authors come from several institutions, including Universitas Pancasila, University of Jaffna, Universitas Muhammadiyah Prof. Dr. HAMKA, Universitas Setia Budi, Federal University Birnin Kebbi, Kano State Polytechnic, Universitas Muhammadiyah Palangkaraya, Prathima Institute of Medical Sciences, Bhaskar Pharmacy College, Ganapathy Degree College, Universitas Muhammadiyah Malang, Universitas Muhammadiyah Magelang, and Universitas Andalas. \u0000Editorial boards are fully aware that there is still room for improvement in this edition, hence with all humility, willing to accept constructive suggestions and feedback for improvements to the publication for the next editions. The editorial board would like to thank all editors and reviewers, and contributors of the scientific articles who have provided the repertoire in this issue. We hope that all parties, especially the contributors, could re-participate for publication in the next edition in August 2022. \u0000Wassalamu’alaikum Wr. Wb.","PeriodicalId":9118,"journal":{"name":"Borneo Journal of Pharmacy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79854542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Formulation of Anti Acne Loose Powder of Bawang Dayak (Eleutherine bulbosa (Mill.) Urb.) Ethanol Extract 霸王大雅抗痘散粉的配方研究市区)。乙醇提取

Borneo Journal of Pharmacy Pub Date : 2022-05-31 DOI: 10.33084/bjop.v5i2.3153

Susi Novaryatiin, Nursheilla Rizky Amalia, S. Ardhany

{"title":"Formulation of Anti Acne Loose Powder of Bawang Dayak (Eleutherine bulbosa (Mill.) Urb.) Ethanol Extract","authors":"Susi Novaryatiin, Nursheilla Rizky Amalia, S. Ardhany","doi":"10.33084/bjop.v5i2.3153","DOIUrl":"https://doi.org/10.33084/bjop.v5i2.3153","url":null,"abstract":"Bawang dayak (Eleutherine bulbosa (Mill.) Urb is one of the notable Iridaceae family, originating from Central Kalimantan, Indonesia. Previous studies have reported that E. bulbosa ethanol extract and its cream preparation have antibacterial properties that can inhibit the growth of acne-causing bacteria and cause no significant skin adverse reaction. This study aimed to make a loose powder preparation from E. bulbosa ethanol extract and determine its physical evaluation and antibacterial activity. Loose powder formulation was made with various concentrations of E. bulbosa ethanol extract, F0 (0%), F1 (5%), F2 (10%), and F3 (15%). Loose powder evaluates for organoleptic, homogeneity, and antibacterial activity by the disc diffusion method. The results show that E. bulbosa ethanol extract can produce a loose powder formulation. The color of the formula is rather yellow (F0), brown-ash (F1), and light brown (F2 and F3), which has a typical mint odor, smooth texture, and homogeneous. All formulations inhibited the growth of Propionibacterium acnes, Staphylococcus epidermidis, and Staphylococcus aureus. This present study showed the potential of Formula 3 (F3) as an anti-acne loose powder due to its organoleptic properties, homogeneity, and antibacterial activity, which has the largest inhibition zone diameter of 17.6 ± 3.1 mm.","PeriodicalId":9118,"journal":{"name":"Borneo Journal of Pharmacy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81466705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Campylobacter Species, Microbiological Source Tracking and Risk Assessment of Bacterial pathogens 弯曲杆菌种类、微生物来源追踪及细菌性病原体风险评估

Borneo Journal of Pharmacy Pub Date : 2022-05-31 DOI: 10.33084/bjop.v5i2.3363

B. Gulumbe, A. Bazata, M. A. Bagwai

{"title":"Campylobacter Species, Microbiological Source Tracking and Risk Assessment of Bacterial pathogens","authors":"B. Gulumbe, A. Bazata, M. A. Bagwai","doi":"10.33084/bjop.v5i2.3363","DOIUrl":"https://doi.org/10.33084/bjop.v5i2.3363","url":null,"abstract":"Campylobacter species continue to remain critical pathogens of public health interest. They are responsible for approximately 500 million cases of gastroenteritis per year worldwide. Infection occurs through the consumption of contaminated food and water. Microbial risk assessment and source tracking are crucial epidemiological strategies to monitor the outbreak of campylobacteriosis effectively. Various methods have been proposed for microbial source tracking and risk assessment, most of which rely on conventional microbiological techniques such as detecting fecal indicator organisms and other novel microbial source tracking methods, including library-dependent microbial source tracking and library-independent source tracking approaches. However, both the traditional and novel methods have their setbacks. For example, while the conventional techniques are associated with a poor correlation between indicator organism and pathogen presence, on the other hand, it is impractical to interpret qPCR-generated markers to establish the exact human health risks even though it can give information regarding the potential source and relative human risk. Therefore, this article provides up-to-date information on campylobacteriosis, various approaches for source attribution, and risk assessment of bacterial pathogens, including next-generation sequencing approaches such as shotgun metagenomics, which effectively answer the questions of potential pathogens are there and in what quantities.","PeriodicalId":9118,"journal":{"name":"Borneo Journal of Pharmacy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76163315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Current Perspectives in Clinical Research: Computer-Assisted Drug Designing, Ethics, and Good Clinical Practice 临床研究的当前观点:计算机辅助药物设计、伦理和良好临床实践

Borneo Journal of Pharmacy Pub Date : 2022-05-31 DOI: 10.33084/bjop.v5i2.3013

V. Kandi, Anusha Vundecode, Tanmai Reddy Godalwar, Sindhusree Dasari, Sabitha Vadakedath, Vikram Godishala

引用次数: 1

Pengelolaan sedıaan metadon pada Program Terapı Rumatan Metadon (PTRM) dı satelıt pelayanan PTRM sed管理ı安美沙酮的项目TerapıRumatan美沙酮(PTRM) dı最新ıt PTRM服务

Borneo Journal of Pharmacy Pub Date : 2022-03-31 DOI: 10.57174/jborn.v2i1.17

Julaeha Julaeha, Nunung Priyatni, R. Rustamaji

{"title":"Pengelolaan sedıaan metadon pada Program Terapı Rumatan Metadon (PTRM) dı satelıt pelayanan PTRM","authors":"Julaeha Julaeha, Nunung Priyatni, R. Rustamaji","doi":"10.57174/jborn.v2i1.17","DOIUrl":"https://doi.org/10.57174/jborn.v2i1.17","url":null,"abstract":"Metadon merupakan jenis narkotika sintetik yang digunakan sebagai terapi substitusi pada Program Terapi Rumatan Metadon (PTRM). Oleh sebab itu, metadon harus diperlakukan sebagaimana narkotika pada umumnya. Tenaga kefarmasian dalam PTRM mempunyai tanggung jawab terhadap pengelolaan metadon. Penelitian ini bertujuan untuk mengevaluasi kesesuaian pengelolaan sediaan metadon di satelit pelayanan PTRM di provinsi Daerah Istimewa Yogyakarta (DIY) berdasarkan pedoman PTRM yang dikeluarkan oleh kemenkes yang meliputi permintaan, penyimpanan, dispensing, dan pelaporan penggunaan metadon. Penelitian ini merupakan penelitian mixed-methods (kualitatif dan kuantitatif) dengan pengambilan data secara prospektif. Instrumen pengukuran kuantitatif dalam penelitian berupa tabel checklist keseuaian pengelolaan metadon berdasarkan pedoman yang berlaku. Data kualitatif bersumber dari hasil wawancara dengan petugas PTRM. Hasil penelitian ini menunjukan bahwa permintaan, penyimpanan, dan pelaporan penggunaan metadon sudah sesuai dengan pedoman pelayanan PTRM. Namun untuk dispensing metadon di satelit pelayanan PTRM masih ada yang dilakukan oleh selain tenaga kefarmasian.","PeriodicalId":9118,"journal":{"name":"Borneo Journal of Pharmacy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73077586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Gambaran penggunaan antikoagulan pada pasien ST-Elevatıon Myocardıal Infarctıon (STEMI)

Borneo Journal of Pharmacy Pub Date : 2022-03-31 DOI: 10.57174/jborn.v2i1.15

Rizqa Aulia Rahmah, Irma Novrianti, Syuhada Syuhada

引用次数: 0