Journal of gastroenterology, pancreatology & liver disorders最新文献_第2页

Hepatobiliary Alterations in Ulcerative Colitis: A Report from a Tertiary Care Centre in Odisha 溃疡性结肠炎的肝胆改变:来自奥里萨邦三级保健中心的报告

Journal of gastroenterology, pancreatology & liver disorders Pub Date : 2016-07-01 DOI: 10.1016/J.JCEH.2016.06.140

P. Padhi, Jimmy Narayan, P. Nath, P. Parida, K. R. Dash, S. Behera, S. Parida, G. Pati, C. Panda, S. Singh

引用次数: 0

Viral Hepatitis: Other Viral Hepatides 病毒性肝炎:其他病毒性肝炎

Journal of gastroenterology, pancreatology & liver disorders Pub Date : 2016-02-16 DOI: 10.1007/978-3-319-30103-7_12

A. Said, A. Ghufran

引用次数: 0

Measurement of Fractional Exhaled Nitric Oxide as a Marker of Disease Activity in Inflammatory Bowel Disease. 测量呼出一氧化氮分数作为炎症性肠病疾病活动性的标志物。

Journal of gastroenterology, pancreatology & liver disorders Pub Date : 2016-01-01 Epub Date: 2016-01-27 DOI: 10.15226/2374-815X/3/1/00146

Erkanda Ikonomi, Robin D Rothstein, Adam C Ehrlich, Frank K Friedenberg

{"title":"Measurement of Fractional Exhaled Nitric Oxide as a Marker of Disease Activity in Inflammatory Bowel Disease.","authors":"Erkanda Ikonomi, Robin D Rothstein, Adam C Ehrlich, Frank K Friedenberg","doi":"10.15226/2374-815X/3/1/00146","DOIUrl":"https://doi.org/10.15226/2374-815X/3/1/00146","url":null,"abstract":"Background and aims: Definitive diagnosis of IBD requires endoscopic and pathologic confirmation. These tools are also used to classify disease activity. Our aim was to determine if the fractional exhaled nitric oxide (FeNO) could be utilized to screen for IBD and assess for disease activity.Methods: We matched weighted IBD cases and controls from the 2009-2010 NHANES dataset. All subjects underwent measurement of FeNO using standardized techniques. We assessed for potential confounders for FeNO measurement including age, height, and asthma. For IBD subjects, we used the presence of diarrhea, fatigue, and weight loss as a proxy for IBD activity. Laboratory parameters examined to estimate disease activity included anemia (≤ 10 g/dl), iron deficiency (ferritin ≤ 20 ng/ml), hypoalbuminemia (≤ 3.2 g/dl), and CRP (≥ 1.1 mg/dl).Results: The weighted sample represented 199,414,901 subjects. The weighted prevalence of IBD was 2,084,895 (1.0%). IBD subjects had nearly the same FeNO level as those without IBD (17.0 ± 16.2 vs. 16.7 ± 14.5 ppb). The odds of a FeNO > 25 ppb was half (OR=0.501; 95% CI 0.497-0.504) for subjects with IBD compared to those without IBD after controlling for confounders. The AUROC curve for FeNO was 0.47 (0.35-0.59). FeNO levels were not higher in patients with laboratory values suggestive of active disease. FeNO levels were higher in IBD patients with diarrhea, rectal urgency, and fatigue but were lower in those with unintentional weight loss.Conclusion: Measurement of FeNO does not appear to be useful to screen for IBD or assess disease activity.","PeriodicalId":90898,"journal":{"name":"Journal of gastroenterology, pancreatology & liver disorders","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936489/pdf/nihms797248.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34655457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Synergy of Transforming Growth Factor Beta 1 and All Trans Retinoic Acid in the Treatment of Inflammatory Bowel Disease: Role of Regulatory T cells. 转化生长因子β 1和全反式维甲酸在炎症性肠病治疗中的协同作用:调节性T细胞的作用

Journal of gastroenterology, pancreatology & liver disorders Pub Date : 2016-01-01 Epub Date: 2016-08-11 DOI: 10.15226/2374-815X/3/4/00166

Dominick L Auci, Nejat K Egilmez

引用次数: 6

Evaluation of Patients' Knowledge Regarding Smoking and Chronic Pancreatitis: A Pilot Study. 评估患者对吸烟和慢性胰腺炎的认识：一项试点研究。

Journal of gastroenterology, pancreatology & liver disorders Pub Date : 2015-07-15

Josna Haritha, C Mel Wilcox

{"title":"Evaluation of Patients' Knowledge Regarding Smoking and Chronic Pancreatitis: A Pilot Study.","authors":"Josna Haritha, C Mel Wilcox","doi":"","DOIUrl":"","url":null,"abstract":"Objective: Over the last decade, a strong association has been found between smoking and chronic pancreatitis. Some studies suggest that smoking may be a more important cause of chronic pancreatitis than alcohol and the two are additive. The primary purpose of our study was to test the use of a questionnaire to assess patient's knowledge regarding the association of smoking with pancreatic disease.Methods: The questionnaire was administered prospectively during a 9 month period in 2013 to patients referred to a pancreas clinic at the University of Alabama Birmingham. The primary purpose of the questionnaire was to investigate patient awareness regarding the association of smoking with pancreatic disease; however, it was also designed for assessing doctor-patient communication regarding smoking in general and pancreatic disease specifically and the patient's stage of change for quitting smoking.Results: Eighteen patients (mean age 52 years; 85% male) were used for the analysis. The data analysis showed that 56% of patients were aware of the relationship between smoking and chronic pancreatitis and 72% were aware about alcohol and pancreatitis. Patients related that physicians were an important reference source for their knowledge regarding the causes of chronic pancreatitis, but only 39% stated that their physician had specifically mention the effect of smoking on the pancreas.Conclusion: Elaborate studies involving greater number of study population, are necessary to better define measuring tools and to further assess patient's knowledge regarding the relationship between smoking and chronic pancreatitis. Additionally, efforts should be directed towards enhancing physician's knowledge on this established relationship and the importance of patient education as well.","PeriodicalId":90898,"journal":{"name":"Journal of gastroenterology, pancreatology & liver disorders","volume":"1 2","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2015-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323167/pdf/nihms-649651.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33058167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Patients' Knowledge Regarding Smoking and Chronic Pancreatitis: A Pilot Study. 评估患者对吸烟和慢性胰腺炎的认知:一项初步研究。

Journal of gastroenterology, pancreatology & liver disorders Pub Date : 2014-07-15 DOI: 10.15226/2374-815X/1/2/00107

J. Haritha, C. Wilcox

{"title":"Evaluation of Patients' Knowledge Regarding Smoking and Chronic Pancreatitis: A Pilot Study.","authors":"J. Haritha, C. Wilcox","doi":"10.15226/2374-815X/1/2/00107","DOIUrl":"https://doi.org/10.15226/2374-815X/1/2/00107","url":null,"abstract":"OBJECTIVE\u0000Over the last decade, a strong association has been found between smoking and chronic pancreatitis. Some studies suggest that smoking may be a more important cause of chronic pancreatitis than alcohol and the two are additive. The primary purpose of our study was to test the use of a questionnaire to assess patient's knowledge regarding the association of smoking with pancreatic disease.\u0000\u0000\u0000METHODS\u0000The questionnaire was administered prospectively during a 9 month period in 2013 to patients referred to a pancreas clinic at the University of Alabama Birmingham. The primary purpose of the questionnaire was to investigate patient awareness regarding the association of smoking with pancreatic disease; however, it was also designed for assessing doctor-patient communication regarding smoking in general and pancreatic disease specifically and the patient's stage of change for quitting smoking.\u0000\u0000\u0000RESULTS\u0000Eighteen patients (mean age 52 years; 85% male) were used for the analysis. The data analysis showed that 56% of patients were aware of the relationship between smoking and chronic pancreatitis and 72% were aware about alcohol and pancreatitis. Patients related that physicians were an important reference source for their knowledge regarding the causes of chronic pancreatitis, but only 39% stated that their physician had specifically mention the effect of smoking on the pancreas.\u0000\u0000\u0000CONCLUSION\u0000Elaborate studies involving greater number of study population, are necessary to better define measuring tools and to further assess patient's knowledge regarding the relationship between smoking and chronic pancreatitis. Additionally, efforts should be directed towards enhancing physician's knowledge on this established relationship and the importance of patient education as well.","PeriodicalId":90898,"journal":{"name":"Journal of gastroenterology, pancreatology & liver disorders","volume":"54 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2014-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80187180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8