International journal of cancer research最新文献

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Expression of Vascular Endothelial Growth Factor Protein in Both Serum Samples and Excised Tumor Tissues of Breast Carcinoma Patients 血管内皮生长因子蛋白在乳腺癌患者血清及切除肿瘤组织中的表达
International journal of cancer research Pub Date : 2016-03-01 DOI: 10.3923/IJCR.2016.152.161
H. Ragab, H. Shaaban, N. A. Maksoud, S. Radwan, Wafaa Abd Elaziz, N. Hafez
{"title":"Expression of Vascular Endothelial Growth Factor Protein in Both Serum Samples and Excised Tumor Tissues of Breast Carcinoma Patients","authors":"H. Ragab, H. Shaaban, N. A. Maksoud, S. Radwan, Wafaa Abd Elaziz, N. Hafez","doi":"10.3923/IJCR.2016.152.161","DOIUrl":"https://doi.org/10.3923/IJCR.2016.152.161","url":null,"abstract":"","PeriodicalId":90856,"journal":{"name":"International journal of cancer research","volume":"12 1","pages":"152-161"},"PeriodicalIF":0.0,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77728327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Spermiographic, 2 and 3-dimensional Quantitative Analysis of Testicular Tissues of Rat Submitted to Citrus paradisi Waste Extract and Cisplatin-induced Cytotoxicity 天竺葵废提取物对大鼠睾丸组织的精子造影、二维和三维定量分析及顺铂诱导的细胞毒性
International journal of cancer research Pub Date : 2016-03-01 DOI: 10.3923/IJCR.2016.176.187
G. Akunna, E. Obikili, G. Anyanwu, E. Esom
{"title":"Spermiographic, 2 and 3-dimensional Quantitative Analysis of Testicular Tissues of Rat Submitted to Citrus paradisi Waste Extract and Cisplatin-induced Cytotoxicity","authors":"G. Akunna, E. Obikili, G. Anyanwu, E. Esom","doi":"10.3923/IJCR.2016.176.187","DOIUrl":"https://doi.org/10.3923/IJCR.2016.176.187","url":null,"abstract":"","PeriodicalId":90856,"journal":{"name":"International journal of cancer research","volume":"32 1","pages":"176-187"},"PeriodicalIF":0.0,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74436257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Prevalence of Oral and Pharyngeal Cancers in Kermanshah Province, Iran: A Ten-year Period 伊朗克尔曼沙阿省口腔癌和咽喉癌的患病率:十年期间
International journal of cancer research Pub Date : 2016-03-01 DOI: 10.3923/IJCR.2016.169.175
H. Mozaffari, B. Izadi, M. Sadeghi, F. Rezaei, R. Sharifi, F. Jalilian
{"title":"Prevalence of Oral and Pharyngeal Cancers in Kermanshah Province, Iran: A Ten-year Period","authors":"H. Mozaffari, B. Izadi, M. Sadeghi, F. Rezaei, R. Sharifi, F. Jalilian","doi":"10.3923/IJCR.2016.169.175","DOIUrl":"https://doi.org/10.3923/IJCR.2016.169.175","url":null,"abstract":"","PeriodicalId":90856,"journal":{"name":"International journal of cancer research","volume":"42 1","pages":"169-175"},"PeriodicalIF":0.0,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78227235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 19
Modifying Effects of Pistachio Nuts on Antioxidant Enzymes in Azoxymethane (AOM)-induced Formation of Aberrant Crypt Foci 开心果对偶氮氧甲烷(AOM)诱导的异常隐窝灶形成过程中抗氧化酶的调节作用
International journal of cancer research Pub Date : 2016-03-01 DOI: 10.3923/IJCR.2016.140.151
J. Boateng, R. L. Miller-Ceb, L. Shackelfor, M. Verghese
{"title":"Modifying Effects of Pistachio Nuts on Antioxidant Enzymes in Azoxymethane (AOM)-induced Formation of Aberrant Crypt Foci","authors":"J. Boateng, R. L. Miller-Ceb, L. Shackelfor, M. Verghese","doi":"10.3923/IJCR.2016.140.151","DOIUrl":"https://doi.org/10.3923/IJCR.2016.140.151","url":null,"abstract":"","PeriodicalId":90856,"journal":{"name":"International journal of cancer research","volume":"68 1","pages":"140-151"},"PeriodicalIF":0.0,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75648744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Nuclear and Cytoplasmic Expression of Survivin in Breast Carcinoma: Correlation with Clinicopathological Parameters Survivin在乳腺癌中的核和细胞质表达:与临床病理参数的相关性
International journal of cancer research Pub Date : 2016-03-01 DOI: 10.3923/IJCR.2016.128.139
H. Shaaban, N. Hafez, H. Ragab, Areeg Ibrahim El Abadi
{"title":"Nuclear and Cytoplasmic Expression of Survivin in Breast Carcinoma: Correlation with Clinicopathological Parameters","authors":"H. Shaaban, N. Hafez, H. Ragab, Areeg Ibrahim El Abadi","doi":"10.3923/IJCR.2016.128.139","DOIUrl":"https://doi.org/10.3923/IJCR.2016.128.139","url":null,"abstract":"","PeriodicalId":90856,"journal":{"name":"International journal of cancer research","volume":"39 1","pages":"128-139"},"PeriodicalIF":0.0,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88905946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
N-myc Downstream Regulated Gene1 (NDRG1) in Cancer Metastasis and Therapeutics N-myc下游调控基因1 (NDRG1)在癌症转移和治疗中的作用
International journal of cancer research Pub Date : 2016-02-01 DOI: 10.3923/IJCR.2016.122.127
Bekesho Geleta, E. Makonnen, S. Abay
{"title":"N-myc Downstream Regulated Gene1 (NDRG1) in Cancer Metastasis and Therapeutics","authors":"Bekesho Geleta, E. Makonnen, S. Abay","doi":"10.3923/IJCR.2016.122.127","DOIUrl":"https://doi.org/10.3923/IJCR.2016.122.127","url":null,"abstract":"","PeriodicalId":90856,"journal":{"name":"International journal of cancer research","volume":"7 1","pages":"122-127"},"PeriodicalIF":0.0,"publicationDate":"2016-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90410489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cyclic Dependent Kinases (CDKs) in Cancer Pathogenesis and Therapeutics 环依赖性激酶(CDKs)在癌症发病机制和治疗中的作用
International journal of cancer research Pub Date : 2016-02-01 DOI: 10.3923/IJCR.2016.109.121
Bekesho Geleta, E. Makonnen, S. Abay
{"title":"Cyclic Dependent Kinases (CDKs) in Cancer Pathogenesis and Therapeutics","authors":"Bekesho Geleta, E. Makonnen, S. Abay","doi":"10.3923/IJCR.2016.109.121","DOIUrl":"https://doi.org/10.3923/IJCR.2016.109.121","url":null,"abstract":"","PeriodicalId":90856,"journal":{"name":"International journal of cancer research","volume":"63 1","pages":"109-121"},"PeriodicalIF":0.0,"publicationDate":"2016-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83105249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
HSPD1, HSPB1 and VDAC1 are Over-expressed in Invasive Ductal Carcinoma of the Breast HSPD1、HSPB1和VDAC1在乳腺浸润性导管癌中过表达
International journal of cancer research Pub Date : 2016-02-01 DOI: 10.3923/IJCR.2016.82.91
M. Alabi, O. Adebawo, O. Daini, S. Somiari, R. Somiari
{"title":"HSPD1, HSPB1 and VDAC1 are Over-expressed in Invasive Ductal Carcinoma of the Breast","authors":"M. Alabi, O. Adebawo, O. Daini, S. Somiari, R. Somiari","doi":"10.3923/IJCR.2016.82.91","DOIUrl":"https://doi.org/10.3923/IJCR.2016.82.91","url":null,"abstract":"","PeriodicalId":90856,"journal":{"name":"International journal of cancer research","volume":"3 1","pages":"82-91"},"PeriodicalIF":0.0,"publicationDate":"2016-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79771363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Antioxidant Potential of Coconut Flour in Caco-2 Colon Cancer Cells 椰子粉对Caco-2结肠癌细胞的抗氧化潜力
International journal of cancer research Pub Date : 2016-01-01 DOI: 10.3923/IJCR.2016.29.39
L. Smith, J. Patterson, L. Walker, M. Verghese
{"title":"Antioxidant Potential of Coconut Flour in Caco-2 Colon Cancer Cells","authors":"L. Smith, J. Patterson, L. Walker, M. Verghese","doi":"10.3923/IJCR.2016.29.39","DOIUrl":"https://doi.org/10.3923/IJCR.2016.29.39","url":null,"abstract":"Coconut Flour (CF) (Cocos nucifera L.) is a sweet by-product of coconut milk that has multifarious utility. The objective of this study was to investigate the chemopreventive potential of coconut flour extracts (defatted and whole) through determination of phytochemical content, antioxidative potential and cytotoxic effects on Caco-2 cells. Phytochemical (total phenolic, total flavonoid) content, Trolox Equivalent Antioxidant Capacity (TEAC), free radical-scavenging ability of 2, 2-diphenyl-1-picrylhydrazyl (DPPH) and Ferric Reducing Antioxidant Potential (FRAP) were determined according to standard protocols. Lactate dehydrogenase (LDH) release (cytotoxicity assay) was used to measure in vitro cell damage of Caco-2 colon cancer cells. Activity of antioxidant enzymes was determined with selected concentrations of extracts (25, 50 and 100 μg mLG). Apoptotic activity was assessed through the activity of caspase-3 and DNA fragmentation Enzyme-Linked Immunosorbant Assay (ELISA). Anti-inflammatory activity was assessed through measuring cycloxygenase-2 (Cox-2). Total phenolic and flavonoid content was 55.46±1.70 mg GAE/100 g and 17.84±2.33 mg CE/100 g. The TEAC was 0.65±0.05 μmol TE/100 g. The DPPH was IC50-74 mg mLG . The FRAP was 0.31±0.21 mmol/Fe gG and ORAC was 2387.78±88.68 μM TE gG 14.13±1.25 mmol/Fe gG. The LDH (%) release for 12 and 24 h was 45.8% at 50 μg mLG and 63.5% at 25 μg mLG. Caspase-3 was 15.46±0.639, Cox-2 was 0.30 U mLG and DNA fragmentation ELISA was 0.39 EF at 50 μg mLG. The results for the antioxidant and detoxification enzymes yielded: Glutathione-S-Transferase (GST) 2.12±0.32 nmol minG mLG, catalase (CAT) 24.65±0.40 U mgG, Glutathione Peroxidase (GPx) 30.4±0 nmol minG mLG, superoxide dismutase (SOD) 305.90±3.89 U mLG and glutathione (GSH) 24.4±0 nmol mLG. Results of this study revealed high phenolic and flavonoid content and suggested cytotoxic and antioxidative potential of coconut flour extracts.","PeriodicalId":90856,"journal":{"name":"International journal of cancer research","volume":"139 1","pages":"29-39"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77227177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Chemopreventive Effect of Acanthus ilicifolius Extract on Modulating Antioxidants, Lipid Peroxidation and Membrane Bound Enzymes in Diethyl Nitrosamine Induced Liver Carcinogenesis 刺槐提取物对二乙基亚硝胺诱导肝癌的抗氧化剂、脂质过氧化和膜结合酶的化学预防作用
International journal of cancer research Pub Date : 2016-01-01 DOI: 10.3923/IJCR.2016.1.16
E. Rajamanick, S. Gurudeeban, K. Satyavani, T. Ramanathan
{"title":"Chemopreventive Effect of Acanthus ilicifolius Extract on Modulating Antioxidants, Lipid Peroxidation and Membrane Bound Enzymes in Diethyl Nitrosamine Induced Liver Carcinogenesis","authors":"E. Rajamanick, S. Gurudeeban, K. Satyavani, T. Ramanathan","doi":"10.3923/IJCR.2016.1.16","DOIUrl":"https://doi.org/10.3923/IJCR.2016.1.16","url":null,"abstract":"Acanthus ilicifolius (Acanthaceae) has received considerable attention due to its wide range of traditional usage in Indian system of medicine. The chemopreventive effect of ethanol extracts of Acanthus ilicifolius (AIEE) on N-nitrosodiethylamine (DEN, 200 mg kgG)-induced experimental liver tumour was investigated in male Wistar rats. Experimental rats were orally treated with AIEE (400 mg kgG b.wt.) for 1 week before the injection of diethyl nitrosamine and continued to be 14 weeks. The changes of lipid peroxidation, antioxidants and membrane bound enzymes were studied in AIEE treated experimental and control rats. The result indicates AIEE treatment effectively suppressed liver tumour induced with DEN as revealed by decrease in the levels of extend of alanine transaminase, aspartate transaminase, alkaline phosphatase, lipid peroxidase, glutathione peroxidase and glutathione-S-transferase with a concomitant increase in enzymatic antioxidant (superoxide dismutase and catalase) levels when compared to those in liver tumour bearing rats. The result of the study concludes significant chemopreventive effect of AIEE against DEN induced liver tumour.","PeriodicalId":90856,"journal":{"name":"International journal of cancer research","volume":"4 1","pages":"1-16"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82952920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
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