Hong Kong journal of ophthalmology : the official publication of the College of Ophthalmologists of Hong Kong = Xianggang yan ke xue kan : Xianggang yan ke yi xue yuan最新文献
Jennifer W H Shum, Bonnie N. K. Choy, J. Chan, W. L. Ho, Stephanie Cheri Woo, J. Lai
{"title":"EX-PRESS shunt implantation in Chinese glaucoma patients: 1-year results","authors":"Jennifer W H Shum, Bonnie N. K. Choy, J. Chan, W. L. Ho, Stephanie Cheri Woo, J. Lai","doi":"10.12809/HKJO-V23N1-231","DOIUrl":"https://doi.org/10.12809/HKJO-V23N1-231","url":null,"abstract":"Aim: To report the safety and efficacy of EX-PRESS glaucoma filtration device implantation in Chinese glaucoma patients.Methods: Records of 38 eyes from 38 Chinese glaucoma patients who underwent EX-PRESS shunt implantation between August 2012 and June 2014 with at least 1 year of follow-up were retrospectively reviewed. Main outcome measures included intraocular pressure (IOP), visual acuity, success rate, number of topical antiglaucoma medications applied, and postoperative complications.Results: The mean IOP reduced significantly from 25.8±12.4 mmHg before surgery to 15.1±6.3 mmHg at 1 year after surgery (p<0.005). Repeated measures ANOVA showed that IOP at all time points after surgery was significantly lower than IOP before surgery. 73.7% of patients achieved complete or qualified success.Conclusions: EX-PRESS shunt implantation is safe and effective in Chinese patients.","PeriodicalId":90844,"journal":{"name":"Hong Kong journal of ophthalmology : the official publication of the College of Ophthalmologists of Hong Kong = Xianggang yan ke xue kan : Xianggang yan ke yi xue yuan","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42617466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Supraorbital nerve schwannoma in a young Chinese man: a case report and review of the literature","authors":"A. Chan, Marcus M. Marcet, Tiffany Wing See Lau","doi":"10.12809/HKJO-V23N1-233","DOIUrl":"https://doi.org/10.12809/HKJO-V23N1-233","url":null,"abstract":"Schwannomas of peripheral branches of the trigeminal nerve are rare. We report a 23-year-old Chinese man who underwent anterior orbitotomy through an upper eyelid crease incision approach for resection of a supraorbital nerve schwannoma. Clinical features, imaging findings, and management considerations are discussed, and the literature reviewed.","PeriodicalId":90844,"journal":{"name":"Hong Kong journal of ophthalmology : the official publication of the College of Ophthalmologists of Hong Kong = Xianggang yan ke xue kan : Xianggang yan ke yi xue yuan","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42017281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Wong, Danny Ng, Nicholas S. K. Fung, Yvonne Y Y Chan, D. C. Chung, M. Ho, C. K. Ko, Joy Leung, Shaheeda Mohammed, Helena P. Y. Sin, Heather H. Y. Tang, R. Wong, T. Lai
{"title":"Treat-and-extend regimen for management of neovascular age-related macular degeneration: recommendations from the Hong Kong Retina Expert Panel","authors":"I. Wong, Danny Ng, Nicholas S. K. Fung, Yvonne Y Y Chan, D. C. Chung, M. Ho, C. K. Ko, Joy Leung, Shaheeda Mohammed, Helena P. Y. Sin, Heather H. Y. Tang, R. Wong, T. Lai","doi":"10.12809/HKJO-V23N1-TE","DOIUrl":"https://doi.org/10.12809/HKJO-V23N1-TE","url":null,"abstract":"Antivascular endothelial growth factor (anti-VEGF) agents are a safe and effective treatment option for neovascular age-related macular degeneration (nAMD). However, undertreatment related to the costs and route of administration of anti-VEGF agents remains a common problem for nAMD patients. The treat-and-extend (T&E) regimen for nAMD has proven to balance clinical effectivity with reduced numbers of injections. However, implementation of the T&E regimen depends on the capacity and resources of clinics and patient compliance. To determine the optimal T&E regimen for Hong Kong, a panel of retina specialists was initiated by MediPaper Medical Communications Limited to discuss the benefits and hurdles in adopting the T&E regimen and to develop recommendations for patient selection based on clinical needs, dosing criteria, and dosing regimen. Key recommendations included selecting patients with only-eye or recurrence for the T&E regimen, pre-booking clinic appointments to reduce patient visits, communicating the T&E regimen with non-vitreoretinal physicians and trainees, extending the maximum dose interval to 16 weeks, and actively engaging patients in decision making.","PeriodicalId":90844,"journal":{"name":"Hong Kong journal of ophthalmology : the official publication of the College of Ophthalmologists of Hong Kong = Xianggang yan ke xue kan : Xianggang yan ke yi xue yuan","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46270974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Use of temporary safety sutures during intrascleral fixation of intraocular lens","authors":"T. C. Chan, Alex L. K. Ng, A. Cheng","doi":"10.12809/hkjo-v22n1p24-6","DOIUrl":"https://doi.org/10.12809/hkjo-v22n1p24-6","url":null,"abstract":"Sutureless intrascleral intraocular lens (IOL) implantation is an advanced scleral fixation technique to eliminate the suture-related complications of erosion and exposure after conventional methods.1 Nonetheless, it is technically challenging. Crushing and pulling of the haptic of a threepiece IOL may cause deformation or breakage and hence tilting or dropping of the IOL. We introduce an additional step to enhance safety of the procedure.","PeriodicalId":90844,"journal":{"name":"Hong Kong journal of ophthalmology : the official publication of the College of Ophthalmologists of Hong Kong = Xianggang yan ke xue kan : Xianggang yan ke yi xue yuan","volume":"22 1","pages":"24-26"},"PeriodicalIF":0.0,"publicationDate":"2018-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42404886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Idiopathic intracranial hypertension: adult versus pediatric patients","authors":"P. K. Leung, Jonathan J C Ho, S. T. Ko","doi":"10.12809/hkjo-v22n1p9-17","DOIUrl":"https://doi.org/10.12809/hkjo-v22n1p9-17","url":null,"abstract":"Idiopathic intracranial hypertension (IIH), also known as benign intracranial hypertension or pseudotumor cerebri, is characterized by increased intracranial pressure secondary to unknown causes. IIH affects both adults and children but predominately young obese females of child-bearing age. IIH gives rise to headache, visual disturbances, and symptoms of raised intracranial pressure. The pathophysiology of IIH remains elusive; postulations include obesity-related hormonal changes, obstruction of the central venous sinus, and hereditary causes. Diagnosing IIH is based on modified Dandy criteria. Diagnosis in children is challenging as symptoms and presentations vary; atypical and delayed presentations are not uncommon. Treatment for IIH includes oral acetazolamide or lumbar puncture; surgical treatment with shunts and optic nerve sheath fenestration is reserved for complicated and recurring cases. Treatment options for children are limited and associated with considerable risks and side effects. Vision loss is debilitating and occurs in 10% of IIH patients. A thorough and collaborative approach in managing IIH is needed. This study reviews the epidemiology, clinical presentation, diagnosis, and management of IIH in adults and pediatric patients.","PeriodicalId":90844,"journal":{"name":"Hong Kong journal of ophthalmology : the official publication of the College of Ophthalmologists of Hong Kong = Xianggang yan ke xue kan : Xianggang yan ke yi xue yuan","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47374076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevalence of eyelid diseases among adults in Hong Kong","authors":"S. Mak, J. Kwok, H. Yuen","doi":"10.12809/hkjo-v22n1p18-21","DOIUrl":"https://doi.org/10.12809/hkjo-v22n1p18-21","url":null,"abstract":"Introduction: Eyelid diseases affect visual function and quality of life. This is the first study to investigate the prevalence of eyelid diseases among the general population in Hong Kong. Methods: On 22 October 2017, The College of Ophthalmologists of Hong Kong and The Hong Kong Ophthalmological Society jointly organized a Public Education Day. A total of 165 participants were re- cruited for eyelid disease screening. Eyelid examination was performed by ophthalmology residents under the supervision of a specialist subspecializing in oculoplas- tics to identify any eyelid diseases (dermatochalasis, ptosis, entropion, ectropion, lash misdirection, presence of eyelid masses, and blepharitis). The prevalence of these eyelid diseases and their association with age and sex were determined. Results: The 165 participants (122 females and 43 males) were all Chinese and were aged 24 to 92 (mean, 68) years; 23.6% were 80 years old. The most common eyelid disease was dermatochalasis, with a prevalence of 61.8%, followed by blepharitis (32.1%), ptosis (7.3%), and eyelid mass (6.7%). Lash misdirec- tion, entropion, and ectropion were uncommon, with a prevalence of 2.4%, 0.6%, and 0%, respectively. Dermatochalasis was more common with increasing age. Other eyelid diseases did not correlate with age. Conclusion: Eyelid diseases are not uncommon among the general population in Hong Kong, particularly dermatochalasis, ptosis, and blepharitis. Eyelid diseases may negatively impact patients functionally and psy- chosocially. Clinicians and the general public should be aware of these eyelid diseases.","PeriodicalId":90844,"journal":{"name":"Hong Kong journal of ophthalmology : the official publication of the College of Ophthalmologists of Hong Kong = Xianggang yan ke xue kan : Xianggang yan ke yi xue yuan","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49348032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Antithrombotic treatment in ophthalmic surgery","authors":"T. Chan, A. Tam, Victoria W. Y. Wong, Ben N M Lam","doi":"10.12809/hkjo-v22n1p5-8","DOIUrl":"https://doi.org/10.12809/hkjo-v22n1p5-8","url":null,"abstract":"Ophthalmic surgery is generally performed in elderly people, many of whom are on systemic medications such as antiplatelet and anticoagulant therapies. These drugs are routinely discontinued preoperatively to prevent severe intraand post-operative bleeding. Nonetheless, premature discontinuation of antiplatelet therapy or interruption of anticoagulation increases the risk of thromboembolic complications including death. It is important to balance the risk of thrombotic complications and the benefit of avoiding intraand post-operative bleeding.","PeriodicalId":90844,"journal":{"name":"Hong Kong journal of ophthalmology : the official publication of the College of Ophthalmologists of Hong Kong = Xianggang yan ke xue kan : Xianggang yan ke yi xue yuan","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46375201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Intraosseous hemangioma at the left lateral canthus: a case report","authors":"J. Y. Chan, H. Yuen","doi":"10.12809/hkjo-v22n1p22-3","DOIUrl":"https://doi.org/10.12809/hkjo-v22n1p22-3","url":null,"abstract":"A 56-year-old Chinese woman presented with a 7-year history of a progressive, painless swelling at the left lateral canthus. Contrast-enhanced computed tomography (CT) of the orbit revealed a hypodense lesion of 1.4 cm at the anterior aspect of the left zygomatic arch. A radiological diagnosis of fibrous dysplasia was made. Debulking of the left lateral wall was performed. Intraoperatively, a diamond burr was used to smooth the surface and resulted in moderate bleeding, which was uncommon for fibrous dysplasia. Hemostasis was achieved with bone wax and direct compression. The pathological diagnosis was an intraosseous hemangioma.","PeriodicalId":90844,"journal":{"name":"Hong Kong journal of ophthalmology : the official publication of the College of Ophthalmologists of Hong Kong = Xianggang yan ke xue kan : Xianggang yan ke yi xue yuan","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45016769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrew Tsin, Nathan Mata, Elia Villazana, Eileen Vidro
{"title":"New developments in the visual cycle: functional role of 11-<i>cis</i> retinyl esters in the retinal pigment epithelium.","authors":"Andrew Tsin, Nathan Mata, Elia Villazana, Eileen Vidro","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Although both 11-cis and all-tmns retinyl esters exist in the retinal pigment epithelium, the relative importance of each in the visual cycle has been unclear. Recent data indicate that there are 2 biochemical pathways leading to the formation of 11-cis retinoids from the retinal pigment epithelium pool of retinyl esters. One well-established pathway is located in the endoplasmic reticulum where all-trans retinyl esters are hydrolyzed, isomerized, and then oxidized to form 11-cis retinal (endoplasmic reticulum pathway). A more recently identified pathway resides within the plasma membrane where 11-cis retinyl esters are hydrolyzed directly to 11-<i>cis</i> retinol (plasma membrane pathway). Either or both pathways may provide 11-<i>cis</i> retinoids for regeneration of rod and cone visual pigments. Recent reports have suggested that the regeneration of rod and cone pigments are carried out by different mechanisms, and that 11-<i>cis</i> retinyl esters (plasma membrane pathway) in the retinal pigment epithelium may be specific to cone pigment regeneration. In this paper we review both visual pathways and consider data in support of the hypothesis that 1 of these 2 pathways' (the plasma membrane pathway) functions to provide visual pigment chromophores selectively for cone photoreceptors.</p>","PeriodicalId":90844,"journal":{"name":"Hong Kong journal of ophthalmology : the official publication of the College of Ophthalmologists of Hong Kong = Xianggang yan ke xue kan : Xianggang yan ke yi xue yuan","volume":"5 1","pages":"25-29"},"PeriodicalIF":0.0,"publicationDate":"2001-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348694/pdf/nihms-588245.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33113111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}