Shazia Jehan, Evan Auguste, Ferdinand Zizi, Seithikurippu R Pandi-Perumal, Ravi Gupta, Hrayr Attarian, Giradin Jean-Louis, Samy I McFarlane
{"title":"Obstructive Sleep Apnea: Women's Perspective.","authors":"Shazia Jehan, Evan Auguste, Ferdinand Zizi, Seithikurippu R Pandi-Perumal, Ravi Gupta, Hrayr Attarian, Giradin Jean-Louis, Samy I McFarlane","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The main characteristics of sleep-disordered breathing (SDB) are airflow limitation, chronic intermittent hypoxia, or apnea; which may lead to tissue hypoperfusion and recurrent arousal from sleep. These episodes of hypoxia or apnea can lead to tissue inflammation, and are causal factors of disturbed sleep in both men and women. Several lines of evidence suggest that sleep patterns differ along the lifespan in both male and female subjects, and this may result from the influence of female gonadotropic hormones on sleep. Compared to men, women have more sleep complaints, as women's sleep is not only influenced by gonadotropins, but also by conditions related to these hormones, such as pregnancy. It is therefore not surprising that sleep disturbances are seen during menopause, too. Factors that may play a role in this type of SDB in women include vasomotor symptoms, changing reproductive hormone levels, circadian rhythm abnormalities, mood disorders, coexistent medical conditions, and lifestyle factors.</p>","PeriodicalId":90623,"journal":{"name":"Journal of sleep medicine and disorders","volume":"3 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323064/pdf/nihms834692.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34766301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shazia Jehan, Evan Auguste, Mahjabeen Hussain, Seithikurippu R Pandi-Perumal, Amon Brzezinski, Ravi Gupta, Hrayr Attarian, Giradin Jean-Louis, Samy I McFarlane
{"title":"Sleep and Premenstrual Syndrome.","authors":"Shazia Jehan, Evan Auguste, Mahjabeen Hussain, Seithikurippu R Pandi-Perumal, Amon Brzezinski, Ravi Gupta, Hrayr Attarian, Giradin Jean-Louis, Samy I McFarlane","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The etiology of premenstrual syndrome (PMS) is unknown; it may be due to the normal effect of hormones during the menstrual cycle as it occurs in the late luteal phase of the menstrual cycle.PMS affects women of childbearing age and remits with the onset of menstruation. The menstrual phase is known to influence stage 2 and REM sleep in women, irrespective of premenstrual dysphoric disorder (PMDD). Women with PMDD showed a decreased response to melatonin in their luteal phase as compared to the follicular phase of the menstrual cycle. However, melatonin duration or timing of offset in the morning has not been reported to correlate with the mood. Rather, improvement in mood-related symptoms of PMDD has been found to be influenced by sleep deprivation, be it sleep restrictions in early or late night. Sleep disturbance and decreased melatonin secretions due to hormonal fluctuations during the luteal phase of the menstrual cycle could explain the sleep complaints of PMDD.</p>","PeriodicalId":90623,"journal":{"name":"Journal of sleep medicine and disorders","volume":"3 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323065/pdf/nihms834696.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34766300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vivek Pillai, Jason R Anderson, Philip Cheng, Luisa Bazan, Sophie Bostock, Colin A Espie, Thomas Roth, Christopher L Drake
{"title":"The Anxiolytic Effects of Cognitive Behavior Therapy for Insomnia: Preliminary Results from a Web-delivered Protocol.","authors":"Vivek Pillai, Jason R Anderson, Philip Cheng, Luisa Bazan, Sophie Bostock, Colin A Espie, Thomas Roth, Christopher L Drake","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Though the efficacy of cognitive behavior therapy for insomnia (CBTI) is well-established, the paucity of credentialed providers hinders widespread access. Further, the impact of alternatives such as web-delivered CBTI has not been adequately tested on common insomnia comorbidities such as anxiety. Therefore, we assessed the impact of an empirically validated web-delivered CBTI intervention on insomnia and comorbid anxiety symptoms. A sample of 22 adults (49.8±13.5 yo; 62.5% female) with DSM-5 based insomnia were randomized to either an active CBTI treatment group (n = 13) or an information-control (IC) group (n = 9). Participants in the CBTI group underwent a standard CBTI program delivered online by a 'virtual' therapist, whereas the IC group received weekly 'sleep tips' and general sleep hygiene education via electronic mail. All participants self-reported sleep parameters, including sleep onset latency (SOL), insomnia symptoms per the Insomnia Severity Index (ISI), and anxiety symptoms per the Beck Anxiety Inventory (BAI) at both baseline as well as follow- up assessment one week post-treatment. There were no significant differences between the CBTI and IC groups on baseline measures. The CBTI group showed significantly larger reductions in BAI scores (t = 2.6; p < .05; Cohen's d = .8) and ISI scores (t = 2.1; p < .05; Cohen's d = .9) at follow-up than did the IC group. Further, changes in SOL from baseline (62.3±44.0 minutes) to follow-up (22.3±14.4 minutes) in the CBTI group were also significantly greater (t = 2.3; p < .05; Cohen's d = .9) than in the IC group (baseline: 55.0±44.2 minutes; follow-up: 50.±60.2 minutes). This study offers preliminary evidence that a web-delivered CBTI protocol with minimal patient contact can improve comorbid anxiety symptoms among individuals with insomnia.</p>","PeriodicalId":90623,"journal":{"name":"Journal of sleep medicine and disorders","volume":"2 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081886/pdf/nihms-1562442.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37756962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alexandria M Reynold, Emily R Bowles, Arpit Saxena, Raja Fayad, Shawn D Youngstedt
{"title":"Negative Effects of Time in Bed Extension: A Pilot Study.","authors":"Alexandria M Reynold, Emily R Bowles, Arpit Saxena, Raja Fayad, Shawn D Youngstedt","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Epidemiologic studies have consistently shown an association of long sleep (≥8 hr) with mortality and multiple morbidities. However, there has been little experimental investigation of the effects of sleep extension. The aim of this study was to examine the effects of time in bed (TIB) extension, on depression, anxiety, sleepiness, and systemic inflammation. Following baseline, 14 healthy sleepers (31.79±10.94 years) were randomized to one of two one-week treatments: (1) a TIB extension treatment involving a fixed sleep schedule in which TIB was increased by 3 hours/night compared with the participants' median baseline TIB; (2) a control treatment involving a fixed schedule in which TIB was the same as the participants' median baseline TIB. Actigraphic recording of sleep was assessed throughout both weeks. Self-reported depression, state anxiety, sleepiness, and sleep quality, as well as blood pressure, and inflammation were assessed at baseline and following the treatment week. Compared with baseline, TIB increased by 127.12±3.92 min and total sleep time increased by 119.88±18.52 min during TIB extension, but decreased slightly in the control treatment. Depression was elevated more following TIB extension (effect size (<i>ES</i>)=-0.86) vs. control (<i>ES</i>=-0.50). Interleukin-6 levels increased by 2-fold following TIB extension (<i>ES</i>=-0.65), but did not change following the control treatment. Sleepiness increased after TIB extension, but decreased after the control treatment. The results revealed negative effects of TIB extension on mood and inflammation. Larger-scale studies involving more prolonged, but less profound sleep extension, are warranted.</p>","PeriodicalId":90623,"journal":{"name":"Journal of sleep medicine and disorders","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2014-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217706/pdf/nihms631948.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32797016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Azizi Seixas, Alberto R Ramos, Georgiana M Gordon-Strachan, Vilma Aparecida da Silva Fonseca, Ferdinand Zizi, Girardin Jean-Louis
{"title":"Relationship between Visual Impairment, Insomnia, Anxiety/Depressive Symptoms among Russian Immigrants.","authors":"Azizi Seixas, Alberto R Ramos, Georgiana M Gordon-Strachan, Vilma Aparecida da Silva Fonseca, Ferdinand Zizi, Girardin Jean-Louis","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Little is known about the association between visual impairment and insomnia symptoms in elderly populations. The purpose of this study was to ascertain associations between self-reported visual impairments and insomnia symptoms in a community-based sample of Russian immigrants.</p><p><strong>Method: </strong>Sample consisted of 307 community-residing Russians (ages: 25-95 years, mean=72.64 ± 9.62; women=54% and men=46%). Semi-structured interviews assessed health-care needs and physical health characteristics. Collected demographic and health-related data were analyzed using SPSS 19.0.</p><p><strong>Results: </strong>Overall, 93% reported at least one of several major health problems: visual impairment (48.4%), hypertension (53%), diabetes (25.7%), arthritis (52.8%), cancer (10.5%), weight problems (34.1%), and anxiety/depressive symptoms (43%), 62% had an insomnia diagnosis. Unadjusted logistic regression analysis showed that individuals with visual impairment were nearly three times as likely as those without to report insomnia symptoms [OR = 2.73, p < 0.01; 95% CI = 1.68-4.48]. Adjusting for the presence of socio demographic variables reduced the odds to 2.68; further adjustment for social isolation and anxiety and depressed symptoms reduced the odds to 2.20.Anxiety/depression mediated the relationship between visual impairment and insomnia.</p><p><strong>Conclusion: </strong>Individuals with visual impairment have twice the odds of reporting insomnia independent of anxiety/depression and social isolation, two common problems affecting quality of life in that population.</p>","PeriodicalId":90623,"journal":{"name":"Journal of sleep medicine and disorders","volume":"1 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442088/pdf/nihms689629.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33338864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}