{"title":"A review of Ramadan fasting and diabetes mellitus: Controversies regarding the effects of Ramadan fasting on diabetic patients","authors":"Z. Shadman, Mahdieh Akhoundan, M. K. Nikoo","doi":"10.22038/JFH.2014.3514","DOIUrl":"https://doi.org/10.22038/JFH.2014.3514","url":null,"abstract":"Although several studies have investigated the effects of Ramadan fasting on diabetic patients, the exact impacts on diabetes control have not been well elucidated yet. There are neither precise quantitative criteria nor clear guidelines regarding Ramadan fasting for diabetic patients. This review aimed to discuss the results of previous studies. The neglected points in performed studies should be considered in the design and interpretation of future research related to Ramadan fasting in diabetic patients. A thorough research was carried out on the internet, using the following keywords: “Ramadan”, “Ramadan fasting”, “Islamic fasting”, “fasting in Ramadan”, and “fasting”, in combination with words such as “diabetes mellitus”, “hyperglycemia”, “hypoglycemia”, and “diabetic ketoacidosis”. Databases including PubMed, Google Scholar, and some regional databases were searched in order to find related articles (cross-sectional, descriptive-analytical, cohort, clinical trial, and review studies), published during 1957-2013. The obtained data showed that Ramadan fasting could be non-risky for partially controlled diabetic patients. However, the safety of Ramadan fasting for diabetic patients with different blood glucose levels and complications is not yet determined. Many deficiencies and limitations are observed in the related studies such as the heterogeneity of participants including differences in lifestyle and circadian rhythm changes. Therefore, well controlled studies need to be performed to evaluate factors affecting blood glucose level during Ramadan fasting.","PeriodicalId":90593,"journal":{"name":"Journal of fasting and health","volume":"2 1","pages":"119-130"},"PeriodicalIF":0.0,"publicationDate":"2014-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68363871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fasting and warfarin","authors":"Y. Lai, H-L Ng","doi":"10.22038/JFH.2014.3311","DOIUrl":"https://doi.org/10.22038/JFH.2014.3311","url":null,"abstract":"Recently, we reported the findings of a study on the effects of Ramadan fasting on a group of 32 Muslim patients taking warfarin.13 Weekly INR (international normalized ratio) readings were taken from subjects with previously stable INRs over a three-month period spanning pre-Ramadan to post-Ramadan. We found a statistically significant increase in the mean INR by 0.23 (p=0.006) during Ramadan from the pre-Ramadan month and decreased by 0.28 (p<0.001) after Ramadan. There was no significant difference (p=1.000) in mean INR between the non-Ramadan months. Importantly, there was a decline in the time within therapeutic range (TTR) during Ramadan with a corresponding increase in TTR above the therapeutic target range. %TTR declined from 80.99% before Ramadan to 69.56% during Ramadan (p=0.453). The first out-of-range INR was seen around 12.1 days (95% CI 9.0-15.1) after the start of fasting and returned within range about 10.8 days (95% CI 7.9-13.7) after Ramadan. Time above range increased from 10.80% pre-Ramadan to 29.87% during Ramadan (p=0.027), while time below range increased from 0.57% during Ramadan to 15.49% post-Ramadan (p=0.006). This observation is directly attributable to the effects of fasting.","PeriodicalId":90593,"journal":{"name":"Journal of fasting and health","volume":"2 1","pages":"104-105"},"PeriodicalIF":0.0,"publicationDate":"2014-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68363909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"EFFECT OF FASTING ON RENAL PHYSIOLOGY","authors":"A. Hendawy","doi":"10.22038/JFH.2014.3509","DOIUrl":"https://doi.org/10.22038/JFH.2014.3509","url":null,"abstract":"A B S T R A C T Article type: Review article Total abstention from food and water from sunrise to sunset during the month of Ramadan, is practiced by hundreds of millions of Muslims throughout the world. This pattern of fasting during Ramadan is different from the usual fasting as people are allowed to eat and drink between sunset and dawn but not after dawn. The amount and type of food (rich in protein, fat and sugar) eaten during the night may also be significantly different to that usually consumed during the rest of the year, while in other countries factors such as poverty ensure that the Ramadan fast results in a reduction in energy intake and a loss of body fat. Also, climate and duration of fasting differs from region to another. According to Islam, sick people are exempted from Fasting, but still a significant number of patients with various chronic diseases including chronic kidney diseases (CKD) insist on fasting in Ramadan due to their personal beliefs and physicians are facing this problem every year: What to advice their patients as there are no guidelines or protocols about who can and who cannot fast. In general no detrimental effects on health have been directly attributed to fasting during Ramadan. However caution is advised for moderate to severe CKD patients and the physicians should monitor their patients carefully during Ramadan in order to avoid any deleterious effects.","PeriodicalId":90593,"journal":{"name":"Journal of fasting and health","volume":"2 1","pages":"110-112"},"PeriodicalIF":0.0,"publicationDate":"2014-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68364069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Participant Compliance to a Six-Month Traditional and Modified Daniel Fast","authors":"R. Bloomer, Alexandra H Toline","doi":"10.22038/JFH.2014.3293","DOIUrl":"https://doi.org/10.22038/JFH.2014.3293","url":null,"abstract":"Background: We have previously reported multiple health benefits in individuals following the Christian-based fasting protocol known as the Daniel Fast (DF). However, our prior work has involved only short-term (21-day) assessments. For dietary modification to have a profound impact on health, compliance to the dietary plan must be established for the long-term. Materials and Methods We determined the 6-month compliance to a traditional (vegan) DF (n=12), as well as a modified DF (n=9; allowing for the inclusion of small amounts of meat and milk) in healthy individuals. Participants completed diet records during the study period and also rated their overall compliance to the assigned dietary plan. Results Compliance to both dietary plans proved to be satisfactory (approximately 80 in the 6th month; 85 in the 3rd month and 95 during the 3rd week). It is noteworthy that it did not show any major differences between groups. Body weight, from baseline toward month 6, saw a decline in participants assigned to both the traditional DF (79.6±5.3 to 75.5±5.5 kg) and the modified DF (80.4±8.0 to 74.3±6.5 kg). Conclusion These data indicated that both the traditional and modified DF, which involve ad libitum (Latin for “at liberty”) feeding, are realistic for individuals to comply with over a period of several months. Such compliance is associated with a weight loss of approximately 5-8 of the body mass and considering the multi-faceted health benefits of this particular dietary approach, it may result in worthy improvements in overall health. Additional studies of the long-term health implications of this fasting method are also required.","PeriodicalId":90593,"journal":{"name":"Journal of fasting and health","volume":"2 1","pages":"90-95"},"PeriodicalIF":0.0,"publicationDate":"2014-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68363854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The effect of fasting on the important molecular mechanisms related to cancer treatment","authors":"Vahideh Keyvani, M. Kerachian","doi":"10.22038/JFH.2014.3510","DOIUrl":"https://doi.org/10.22038/JFH.2014.3510","url":null,"abstract":"A B S T R A C T Article type: Original article Fasting does have remarkable benefits in the treatment of cancer and another diseases such as metabolic syndrome, diabetes, and a multitude of other chronic diseases. It has been determined that fasting could play an important role during cancer treatment and progression via the regulation of insulin-like growth factor-1 (IGF-1) as well as other growth factors. Also, it has been shown that fasting would enhance the chemotherapy effect in cancer patients, selectively protects normal cells and organisms from chemotherapy toxicity, while simultaneously sensitizing tumors. In this article, we discuss the benefits of fasting in the treatment of cancer through several different molecular pathways.","PeriodicalId":90593,"journal":{"name":"Journal of fasting and health","volume":"2 1","pages":"113-118"},"PeriodicalIF":0.0,"publicationDate":"2014-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68363768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Preoperative fasting guidelines and their importance for children’s health","authors":"M. Seyedhejazi","doi":"10.22038/JFH.2014.3364","DOIUrl":"https://doi.org/10.22038/JFH.2014.3364","url":null,"abstract":"Article type: Letter to Editor Children, similar to adults, are required to fast before general anesthesia in order to reduce the volume and acidity of stomach contents. It is thought that NPO regulations reduce the risk of regurgitation and aspiration of gastric contents during surgery. Recent developments have encouraged a shift from the standard 'nil by mouth from midnight' fasting policy to more relaxed regimens. Preoperative NPO status for each patient must be regulated according to his/her age and timing of the surgery, the night before the operation (2 hours for clear fluids and 4-6 hours for solid foods and milk before the surgery, considering his/her age). Article History: Received: 29 Aug 2014 Accepted: 9 Sep 2014 Published: 20 Sep 2014","PeriodicalId":90593,"journal":{"name":"Journal of fasting and health","volume":"2 1","pages":"106-108"},"PeriodicalIF":0.0,"publicationDate":"2014-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68363916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Issues pertaining to PET imaging of liver cancer","authors":"Z. Lee, G. Luo","doi":"10.22038/JFH.2014.3092","DOIUrl":"https://doi.org/10.22038/JFH.2014.3092","url":null,"abstract":"Positron emission tomography (PET) imaging using 2-deoxy-2-[F-18]fluoro-D-glucose (FDG) has proven valuable in the diagnosis, staging and restaging for many cancers. However, its application for liver cancer has remained limited owing in part to the relatively high background uptake of the tracer in the liver plus the significant variability of the tumor specific uptake in liver cancer among patients. Thus, for primarily liver cancer, in particular, hepatocellular carcinoma (HCC), radio-tracers with better tumor-enhancing uptake/retention are still sought in order to harness the great power of PET imaging. Here, we reviewed some recent investigations with lipid-based small molecule PET radio-tracers with relevance to fasting, and discuss their potential in the diagnosis and staging of HCCs.","PeriodicalId":90593,"journal":{"name":"Journal of fasting and health","volume":"2 1","pages":"62 - 64"},"PeriodicalIF":0.0,"publicationDate":"2014-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68363140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of the number of Ramadan fasting days on maternal and neonatal outcomes","authors":"H. Boskabadi, A. Mehdizadeh, Zeynab Alboumiri","doi":"10.22038/JFH.2014.3270","DOIUrl":"https://doi.org/10.22038/JFH.2014.3270","url":null,"abstract":"Introduction: Gynecologists and perinatologists are left with many unanswered questions and concerns regarding fasting during pregnancy and its effects on maternal and neonatal health. The current study was conducted to investigate the correlation between the number of Ramadan fasting days and pregnancy outcomes. Materials & Methods: In this descriptive, analytical study, 641 newborns, whose mothers had fasting experience during pregnancy, were enrolled and allocated to three groups, based on the number of maternal fasting days during pregnancy (group A: ≤10 days, group B: 11-20 days, and group C: 21-30 days). Demographic and anthropometric data of neonates and mothers were recorded. Descriptive statistics, Chi-square, and non-parametric tests were performed for data analysis. Results: No statistically significant difference was found in maternal weight (during the last month of pregnancy), neonatal height, incidence of pre-term labor, or neonatal congenital abnormality in the three groups. Increased number of fasting days was not correlated with decreased neonatal head circumference or weight, while 1- and 5-minute Apgar scores significantly improved (P<0.05). Conclusion: As the current findings indicated, with increasing number of fasting days, neonatal birth weight or maternal weight did not decrease. In addition, incidence of pre-term labor and low birth weight did not increase, while significant improvements were detected in 1- and 5-minute Apgar scores. Since pregnancy is a delicate state for women, further research on larger populations is recommended to evaluate other parameters and obtain more convincing results about the effects of Ramadan fasting on pregnant women.","PeriodicalId":90593,"journal":{"name":"Journal of fasting and health","volume":"2 1","pages":"84-89"},"PeriodicalIF":0.0,"publicationDate":"2014-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68363794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Z. Mishmast, Reza Rahimzadeh Oskuee, Amir Aryan, K. Ghafarzadegan, K. Ghazvini
{"title":"Impact of Short‐term, Repeated Water Fasting on the Weight of Mice","authors":"Z. Mishmast, Reza Rahimzadeh Oskuee, Amir Aryan, K. Ghafarzadegan, K. Ghazvini","doi":"10.22038/JFH.2014.3257","DOIUrl":"https://doi.org/10.22038/JFH.2014.3257","url":null,"abstract":"Introduction: Caloric restriction is a strategy applied for weight loss. Water fasting is a popular way for obesity treatment. However, little is known about the impact of water fasting on weight. Therefore, this study was conducted to investigate the effect of short-term, repeated water fasting on the weight of mice. Methods: In this study, the physiological effect of short-term, repeated water fasting on the weight of female mice was evaluated. At 6 weeks of age, mice were randomly assigned to either repeated-fasting or control group (fed ad libitum). Each group consisted of twenty mice. As the fasting period started, the repeated-fasting group had access to only water; animals had free access to food and water on non-fasting days. Body weight of each group before, during, and after the fasting period was recorded. Results: Body weight of the fasting group significantly decreased, unlike the control group. However, the fasting group gained weight rapidly after being re-fed and became significantly heavier than mice in the control group (P<0.01). Interestingly, the average body weight of the fasting group increased, compared to that of the control group; in fact, the fasting mice weighed approximately 10% heavier than the control ones. Conclusion: Repeated water fasting was not only ineffective for weight loss but also increased the body weight of fasting mice.","PeriodicalId":90593,"journal":{"name":"Journal of fasting and health","volume":"2 1","pages":"76-79"},"PeriodicalIF":0.0,"publicationDate":"2014-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68363453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Philosophy of Fasting in Quran and Islamic Narratives and Its Relationship with Human Health, Based on Scientific Notions","authors":"M. Mousavi","doi":"10.22038/JFH.2014.3177","DOIUrl":"https://doi.org/10.22038/JFH.2014.3177","url":null,"abstract":"Abstinence from eating and drinking on long hot summer days is no easy task. In fact, it is considered the greatest “Jihad” in Islamic tradition. Here, the main question is concerned with the importance of fasting, its purposes, and advantages for individuals. We need to determine if fasting plays a role in overcoming human problems. This article, by using an analytical approach, states Quranic verses and Hadiths and reviews the philosophy of fasting in response to two questions: 1) What is the philosophy of fasting in Quran and Hadiths?, and 2) What role does it play in maintaining human health? Therefore, Islamic verses and narratives, concerning the importance of fasting in maintaining health, are reviewed, using the opinions of some scientists.","PeriodicalId":90593,"journal":{"name":"Journal of fasting and health","volume":"14 1","pages":"71-75"},"PeriodicalIF":0.0,"publicationDate":"2014-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68363200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}