International journal of diabetology & vascular disease research最新文献

{"title":"Inchoate Disaster of Covid-19: A Systematic Review on Risk Factors Triggering Morbidity and Fatality Progression","authors":"Sumit Oberoi","doi":"10.19070/2328-353x-2100051","DOIUrl":"https://doi.org/10.19070/2328-353x-2100051","url":null,"abstract":"","PeriodicalId":90543,"journal":{"name":"International journal of diabetology & vascular disease research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48322278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use Of Sodium - Glucose Co - Transporter - 2 Inhibitors In Hospitalized Patients With Acute Heart Failure","authors":"Nasser Mikhai","doi":"10.19070/2328-353x-2100050","DOIUrl":"https://doi.org/10.19070/2328-353x-2100050","url":null,"abstract":"","PeriodicalId":90543,"journal":{"name":"International journal of diabetology & vascular disease research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44199748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Glycemic Control between Intensive Insulin Regimen and Continuous Subcutaneous Insulin infusion: A Meta-Analysis Report of Type-1 Diabetics from Randomized Controlled Trials","authors":"K. Aziz, A. Othman","doi":"10.1101/2020.06.01.20119693","DOIUrl":"https://doi.org/10.1101/2020.06.01.20119693","url":null,"abstract":"Achieving glycemic control and targets are challenging in type-1 diabetes management. To achieve this, intensive insulin therapy or multiple daily injections (MDI) and continuous subcutaneous insulin infusion (CSII) or pump therapy have been used in various health care settings. However, there has been a debate on their superiority. Some of researchers have recommended MDI, while others SCII. We compared MDI with CSII by a literature search. We have conducted mata-analysis for MDI and CSII on ten randomized controlled trials on 809 type-1 diabetics 809, MDI (N=394) or CSII (N=415). Heterogeneity between trials was quantified by conventional Q-statistic (Cochran heterogeneity statistic) and Higgins I2 statistic with 0-40% representing negligible heterogeneity, 30-60% moderate heterogeneity, 50-90% substantial heterogeneity and 75-100% considerable heterogeneity. tau-squared ({tau}2) was used to observe between-study random-effects variance. Meta Analyst software was used to analyze the data and to conduct meta-analysis. SPSS was used to analyze HbA1c student t-test for MDI and CSII. A random-effect analysis (( DerSimonian-Laird method) performed on ten studies found that the percentage of HbA1c was lower in patients receiving CSII compared with those receiving MDI; standardized mean difference (SMD) was 0.441 , 95% confidence interval 0.267 to 0.616, p < 0.001; equivalent to a difference of 0.39%, favoring CSII. I2 statistic was 20.9 ; {tau}2= 0.016; Q=11.378 with df = 9, indicating that heterogeneity was not significant (heterogeneity p-value = 0.251). Patients on CSII demonstrated significantly lower values (8.2 SD 0.72 versus 7.73 SD 0.72 ; p-value <0.001 respectively). This statistical and meta-analysis favors the usage of insulin pump therapy. We concluded that patient centered approach should be used while selecting the patients for insulin pump (CSII) or MDI.","PeriodicalId":90543,"journal":{"name":"International journal of diabetology & vascular disease research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48087416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TRACK Implementation among Bangladeshi Population","authors":"Mohiuddin Ak","doi":"10.19070/2328-353x-1900048","DOIUrl":"https://doi.org/10.19070/2328-353x-1900048","url":null,"abstract":"million people with undetected diabetes in Bangladesh and this number will be double by 2025 [10]. Das et al. [11] reported prevalence of dyslipidemia was over 70% to both male and female subjects, which indicates the urgency of lifestyle intervention strategies to prevent and manage this important health problem and risk factor. Among 8400 stroke patients from different hospitals in Bangladesh over Abstract With the increasing burden of non-communicable diseases in low-income and middle-income countries (LMICs), biological risk factors, such as hyperglycemia, are a major public health concern in Bangladesh. Optimization of diabetes management by positive lifestyle changes is urgently required for prevention of comorbidities and complications, which in turn will reduce the cost. Diabetes had 2 times more days of inpatient treatment, 1.3 times more outpatient visits, and nearly 10 times more medications than non- diabetes patients, as reported by British Medical Journal. And surprisingly, 80% of people with this so called “Rich Man’s Disease” live in low- and middle-income countries. According to a recent study of American Medical Association, China and India collectively are home of nearly 110 million diabetic patients. The prevalence of diabetes in this region is projected to increase by 71% by 2035. Bangladesh was ranked as the 8th highest diabetic populous country in the time period of 2010-2011. In Bangladesh, the estimated prevalence of diabetes among adults was 9.7% in 2011 and the number is projected to be 13.7 million by 2045. The cost of diabetes care is considerably high in Bangladesh, and it is primarily driven by the medicine and hospitalization costs. According to Bangladesh Bureau of Statistics, in 2017 the annual average cost per T2DM was $864.7, which is 52% of per capita GDP of Bangladesh and 9.8 times higher than the general health care cost. Medicine is the highest source of direct cost (around 85%) for patients without hospitalization. The private and public financing of diabetes treatment will be severely constrained in near future, representing a health threat for the Bangladeshi population.","PeriodicalId":90543,"journal":{"name":"International journal of diabetology & vascular disease research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45003291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between High Sensitive-C Reactive Protein and Lipid Cardiovascular Risk Factors in Apparently Healthy Nigerian Young Adults","authors":"Sonuga Oo, Sonuga Aa","doi":"10.19070/2328-353x-1900047","DOIUrl":"https://doi.org/10.19070/2328-353x-1900047","url":null,"abstract":"It’s a known fact that 50% of all myocardial infarctions occur among individuals without overt hyperlipidaemia, inspite of the strong association of lipid concentrations with coronary heart disease risk (CHD) [2]. It has been shown that about 20% of all coronary events occurred in the absence of any of the traditional risk factors, such as hypertension, diabetes mellitus, hyperlipidaemia and smoking [3]. These findings raise the query if these conventional risk factors are sufficient to recognize individuals at increased risk of CHD. Therefore various non-lipid atherogenic markers have been suggested in an effort to better determine individuals at risk of CHD, these include markers of inflammation (high sensitivity C-reactive protein, interleukins, adhesion molecules, heat shock proteins); markers of fibrinolytic and haemostatic function (D-dimers, fibrinogen, thrombinantithrombin III complex); homocysteine to mention but few. Of all these non-lipid risk markers available, high sensitivity C-reactive protein (hs-CRP) is considered to be the most robust tool with test uniqueness desirable and favorable for clinical use as novel marker for CHD risk [4].","PeriodicalId":90543,"journal":{"name":"International journal of diabetology & vascular disease research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41416485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Total Adiponectin and Risk of Symptomatic Lower Extremity Peripheral Vascular Disease in Type 2 Diabetes Mellitus","authors":"S. Kumar","doi":"10.19070/2328-353X-1900046","DOIUrl":"https://doi.org/10.19070/2328-353X-1900046","url":null,"abstract":"","PeriodicalId":90543,"journal":{"name":"International journal of diabetology & vascular disease research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44461639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Knowledge and Patient Counseling to the Patient with Diabetes on Diabetic Foot Care in Tertiary Care Hospital","authors":"A. UdayaBhaskar, M. MadhanMohanRao","doi":"10.19070/2328-353x-1900045","DOIUrl":"https://doi.org/10.19070/2328-353x-1900045","url":null,"abstract":"1 Annamacharya College of Pharmacy, Rajampet, A.P, India. JNTU, Ananthapur, A.P, India. 2 Associate Professor, Department of General Medicine, Rajiv Gandhi Institute of Medical Sciences, Kadapa, A.P, India.Dr. NTR University of Health Sciences. Vijayawada, A.P, India. 3 Associate Professor, Department of Pharmacology, Annamacharya College of Pharmacy, Rajampet, A.P, India. JNTU, Ananthapur, A.P, India.","PeriodicalId":90543,"journal":{"name":"International journal of diabetology & vascular disease research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49104829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Antidiabetic Drug Metformin and Male Fertility: An Update","authors":"C. João, F. Pedro","doi":"10.19070/2328-353X-1900014E","DOIUrl":"https://doi.org/10.19070/2328-353X-1900014E","url":null,"abstract":"Diabetes mellitus is a chronic disease with pandemic proportions. It has been estimated that 451 million people were diabetic in 2017 and recent statistics suggest that a worrisome 693 million people will suffer from diabetes in 2045 [1]. This metabolic disease is defined by impaired plasma glucose levels [2], which is due to insufficient insulin secretion or/and insulin resistance [3]. Thus, diminished insulin bioactivity causes a dysregulation on glucose metabolism in multiple tissues and, if not properly treated, hyperglycaemia and low insulin levels can evolve to other conditions and co-morbidities of distinct nature [4].","PeriodicalId":90543,"journal":{"name":"International journal of diabetology & vascular disease research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41830311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Walking Economy is Impaired in Older Men and Women with Type 2 Diabetes.","authors":"A W Gardner, P S Montgomery","doi":"10.19070/2328-353X-SI03002","DOIUrl":"10.19070/2328-353X-SI03002","url":null,"abstract":"<p><strong>Objective: </strong>We compared the walking economy in older participants with and without type 2 diabetes.</p><p><strong>Methods: </strong>Walking economy was determined in 115 older participants with type 2 diabetes and 130 older control participants without diabetes by continuously measuring oxygen uptake during a treadmill test in which the work rate was at a constant speed of 2 mph and a grade of 0% for a duration of 10 minutes. Participants also completed a Balke treadmill protocol for the determination of peak oxygen uptake, defined as the highest oxygen uptake value attained during the final work stage attained. Fractional utilization was then calculated as the walking economy oxygen uptake divided by peak oxygen uptake, expressed as a percentage.</p><p><strong>Results: </strong>Compared to those without diabetes, participants with type 2 diabetes were older (p=0.042), had higher prevalence of men (p=0.034), obesity (p=0.010), chronic kidney disease (p=0.020), peripheral artery disease (p=0.024), and had a higher body mass index (p=0.025), and waist/hip ratio (p=0.006). After adjusting for these variables, the participants with diabetes had higher walking economy (p<0.001), fractional utilization (p<0.001), and lower peak oxygen uptake (p<0.001) than those without diabetes (p<0.001).</p><p><strong>Conclusions: </strong>Older men and women with type 2 diabetes are less economical when they ambulate at a given speed than compared to control participants without diabetes, independent of their greater co-morbid burden. The impaired walking economy in the diabetic participants is further magnified by their lower aerobic fitness, thereby leading to a higher fractional utilization of oxygen consumed during a given walking task.</p>","PeriodicalId":90543,"journal":{"name":"International journal of diabetology & vascular disease research","volume":"2016 Suppl 3","pages":"7-12"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376089/pdf/nihms-811957.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34882249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prediabetes: The Variation between HbA1c and Fasting Plasma Glucose.","authors":"K A M White,&nbsp;S Daneshvari,&nbsp;J Lilyquist,&nbsp;L Luo,&nbsp;L E Steffen,&nbsp;A Bivin,&nbsp;N Gurule,&nbsp;G M Ducasa,&nbsp;S M Torres,&nbsp;R Lindeman,&nbsp;S Sankarappan,&nbsp;M Berwick","doi":"10.19070/2328-353X-SI02001","DOIUrl":"https://doi.org/10.19070/2328-353X-SI02001","url":null,"abstract":"<p><strong>Purpose: </strong>The prevalence of Diabetes Type 2 is on the rise internationally. Currently, Fasting Plasma Glucose (FPG) and HbA1c are both used to determine if an individual is diabetic or prediabetic. We aimed to describe the prevalence of diabetes, prediabetes, and glycemic control in a population-based sample of elderly Hispanic and non-Hispanic White participants in New Mexico.</p><p><strong>Methods: </strong>To do this, we compared HbA1c with FPG using Chi-Square analysis across gender and ethnicity to provide information for future health care policy. We also performed non-parametric regression using a locally weighted smoothing technique to investigate the relationship between FPG and HbA1c levels.</p><p><strong>Results: </strong>Our analysis identifies a large variation between the sensitivity of HbA1c and FPG in the identification of both prediabetes and diabetes. Interestingly, 95% of diabetics defined by FPG are also defined by HbA1c, representing overlap between the two measures. When comparing the prevalence of prediabetes between the two measures, the overlap of FPG with HbA1c was only 30% and HbA1c identifies more individuals as prediabetic than FPG. Prevalence of diabetes was also higher when defined by HbA1c compared to FPG and the overall agreement between HbA1c and FPG appears to be poor particularly by sex and ethnicity (K=0.22-0.34). Glycemic control was poor overall with Hispanics displaying a larger amount of uncontrolled diabetes.</p><p><strong>Conclusion: </strong>We compared HbA1c and FPG by gender and ethnicity and showed both measures of diabetes differ in their sensitivity across ethnic groups. Our results suggest that using HbA1c, rather than FPG, results in higher rates of prediabetes and diabetes, a finding with numerous implications for health care practice.</p>","PeriodicalId":90543,"journal":{"name":"International journal of diabetology & vascular disease research","volume":"Suppl 2 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.19070/2328-353X-SI02001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35073704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}