Cancer treatment communications最新文献_第10页

A patient with neuroendocrine carcinoma of the urinary bladder and paraneoplastic degenerative parencephalitis: A case report and review of the literature 膀胱神经内分泌癌合并副肿瘤退行性脑炎1例报告及文献复习

Cancer treatment communications Pub Date : 2014-01-01 DOI: 10.1016/j.ctrc.2013.12.001

George Fotopoulos , George Pentheroudakis , Elli Ioachim , Nicholas Pavlidis

引用次数: 4

Myoepithelial carcinoma of the head and neck: A report of 23 cases and literature review 头颈部肌上皮癌23例报告并文献复习

Cancer treatment communications Pub Date : 2014-01-01 DOI: 10.1016/j.ctrc.2014.08.002

Tao Xu , Zhiwei Liao , Jun Tang , Li Guo , Huizhi Qiu , Yuanhong Gao , Weihan Hu

{"title":"Myoepithelial carcinoma of the head and neck: A report of 23 cases and literature review","authors":"Tao Xu , Zhiwei Liao , Jun Tang , Li Guo , Huizhi Qiu , Yuanhong Gao , Weihan Hu","doi":"10.1016/j.ctrc.2014.08.002","DOIUrl":"10.1016/j.ctrc.2014.08.002","url":null,"abstract":"<div><h3>Objective</h3><p>Myoepithelial carcinoma (MC) of head and neck is extremely rare. The relevant literature consists only of case reports, and consequently many of its clinical characteristics and optimal treatment strategies remain unknown.</p></div><div><h3>Methods</h3><p>We retrospectively analyzed 23 patients diagnosed with MC of the head and neck between 1991 and 2005. Most patients were treated with surgery and postoperative radiotherapy or adjuvant chemotherapy. The recurrence, survival and local control rates were evaluated.</p></div><div><h3>Results</h3><p>Thirteen (56.5%) patients were male and 10 were female with a median age of 52 years (range: 15–77 years). The parotid was the most frequently involved site (39.1%). Eighteen patients underwent surgery as their initial treatment and nine of these received postoperative radiotherapy. The 3-year and 5-year overall survival rates were 59% and 31.8%, respectively. The local relapse rate was 30.4% (6/23); eight patients had a distal metastasis, and the lung was the most common site. There was no difference in the local control and survival rates between patients who received surgery alone and those with additional postoperative radiotherapy (<em>p</em>=0.059). Two patients had partial response after chemotherapy with dacarbazine.</p></div><div><h3>Conclusions</h3><p>The detailed clinical data presented here reveal several new characteristics of MC of the head and neck. Postoperative radiotherapy did not improve the prognosis. Chemotherapeutic regimens that include dacarbazine might be useful.</p></div>","PeriodicalId":90461,"journal":{"name":"Cancer treatment communications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ctrc.2014.08.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54049787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 26

Fungating malignant phyllodes tumor 恶性叶状瘤

Cancer treatment communications Pub Date : 2014-01-01 DOI: 10.1016/j.ctrc.2014.08.001

Matthew Schultzel , Ranjeet Kalsi , Faith Goldman

引用次数: 0

Progressive brain metastases in an EGFR mutated adenocarcinoma of the lung: Response to gefitinib after progression on erlotinib EGFR突变的肺腺癌的进展性脑转移:厄洛替尼进展后对吉非替尼的反应

Cancer treatment communications Pub Date : 2014-01-01 DOI: 10.1016/j.ctrc.2014.03.001

C. Leitner , R. von Moos , M. Mark , M. Früh , R. Cathomas

引用次数: 2

Combined small cell lung cancer originated from small pure ground-glass nodule—Long-term observation after computed tomography screening 单纯小磨玻璃结节合并小细胞肺癌- ct筛查后的长期观察

Cancer treatment communications Pub Date : 2014-01-01 DOI: 10.1016/j.ctrc.2014.07.001

Kentaro Miura , Ryoichi Kondo , Makoto Kurai , Junichi Hotta , Toshiro Suzuki , Nobuki Sakaguchi , Muneharu Hayasaka , Keiko Ishii

引用次数: 0

Patient, physician and contextual factors are influential in the treatment decision making of older adults newly diagnosed with symptomatic myeloma 患者、医生和环境因素对新诊断为症状性骨髓瘤的老年人的治疗决策有影响

Cancer treatment communications Pub Date : 2014-01-01 DOI: 10.1016/j.ctrc.2014.08.003

Joseph D. Tariman , Ardith Doorenbos , Karen G. Schepp , Pamela S. Becker , Donna L. Berry

{"title":"Patient, physician and contextual factors are influential in the treatment decision making of older adults newly diagnosed with symptomatic myeloma","authors":"Joseph D. Tariman , Ardith Doorenbos , Karen G. Schepp , Pamela S. Becker , Donna L. Berry","doi":"10.1016/j.ctrc.2014.08.003","DOIUrl":"10.1016/j.ctrc.2014.08.003","url":null,"abstract":"<div><h3>Aims</h3><p>To examine patient perspectives on their personal and contextual factors relevant to TDM. The second aim was to describe physician perspectives on the TDM in older adults (≥60 y.o.) diagnosed with symptomatic MM.</p></div><div><h3>Study design</h3><p>Descriptive, cross-sectional.</p></div><div><h3>Methodology</h3><p>A semi-structured interview schedule was administered. Directed content analysis procedures were used to develop major themes from the patient and physician participant interviews.</p></div><div><h3>Results</h3><p>Themes related to treatment decision making among patient participants include various decisional role preferences; several sources of information related to myeloma; contextual and patient-specific factors influence treatment decisions; negative perceptions related to the treatment decision-making process exist; strong desire to be in remission and to live a longer life; For physician participants, top themes related to decision making were: QOL or survival considerations or simultaneously considerations of treatment effectiveness, QOL and survival; screening patients for eligibility for autologous HSCT; time is a barrier to effective TDM; Various methods were used to assess patient decisional role preferences.</p></div><div><h3>Conclusions</h3><p>Treatment decision making in older adults newly diagnosed with symptomatic myeloma is influenced by personal, social and contextual factors. Patients must be given the opportunity to choose the best possible treatment within the limits of the patient’s personal, social and medical contexts.</p></div>","PeriodicalId":90461,"journal":{"name":"Cancer treatment communications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ctrc.2014.08.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32945027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 33

Acrometastasis from an epidermal-growth-factor-receptor (EGFR) mutation-positive lung adenocarcinoma 表皮生长因子受体(EGFR)突变阳性肺腺癌的肢端转移

Cancer treatment communications Pub Date : 2014-01-01 DOI: 10.1016/j.ctrc.2014.08.004

Mau-Ern Poh, Chong-Kin Liam, Jiunn-Liang Tan, Yong-Kek Pang, Chee-Kuan Wong, Ken-Siong Kow

{"title":"Acrometastasis from an epidermal-growth-factor-receptor (EGFR) mutation-positive lung adenocarcinoma","authors":"Mau-Ern Poh, Chong-Kin Liam, Jiunn-Liang Tan, Yong-Kek Pang, Chee-Kuan Wong, Ken-Siong Kow","doi":"10.1016/j.ctrc.2014.08.004","DOIUrl":"10.1016/j.ctrc.2014.08.004","url":null,"abstract":"<div><p>We report the first case of epidermal-growth-factor-receptor (EGFR) mutation-positive lung adenocarcinoma with acrometastasis in a 51-year-old woman who presented with a swelling on her right hand. Magnetic resonance imaging revealed an expansile lesion at the base of the 5th metacarpal bone of her right hand with cortical erosion and patchy enhancement suggestive of a malignant transformation of a giant-cell tumor. A core needle biopsy of this lesion showed a metastatic adenocarcinoma on histopathological examination which was immunoreactive to cytokeratin (CK) 7 and thyroid transcription factor (TTF)-1 but not to CK20 suggesting a lung primary. A chest radiograph and computed tomography (CT) scan revealed a right upper lobe lung mass. Fluoro-deoxyglucose hypermetabolism was noted in the lung mass and the right 5th metacarpal bone lesion but not elsewhere on positron-emission-tomography/CT scan. Needle biopsy of the lung mass showed adenocarcinoma with histopathological and immunohistochemical features similar to that of the right 5th metacarpal bone lesion. Both the primary lung adenocarcinoma and the acrometastatic lesion were tested positive for EGFR mutation in exon 21 (L858R substitution). She underwent R0 resection of her right upper and middle lobes with systematic mediastinal lymph nodes resection and wide excision of the metacarpal metastasis followed by cytotoxic chemotherapy. A curative approach with complete resection of the primary tumor and oligometastastic site in Stage IV non-small cell lung carcinoma (NSCLC) followed by additive cytotoxic chemotherapy has not been reported to date and as such there is still no data on disease-free survival with this approach.</p></div>","PeriodicalId":90461,"journal":{"name":"Cancer treatment communications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ctrc.2014.08.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54049801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Malignant mixed Mullerian tumor of the cervix – case report 宫颈恶性混合性苗勒氏瘤1例报告

Cancer treatment communications Pub Date : 2014-01-01 DOI: 10.1016/j.ctrc.2014.02.001

Erik Kudela , Pavol Slavik , Jozef Visnovsky , Pavol Buocik , Jana Sivakova , Petra Sumichrastova , Lukas Plank , Jan Danko

引用次数: 4

Platypnea-orthodeoxia syndrome following left pneumonectomy for early stage non-small cell lung cancer 早期非小细胞肺癌左肺切除术后肺动脉-正氧综合征

Cancer treatment communications Pub Date : 2014-01-01 DOI: 10.1016/j.ctrc.2013.09.001

R. Califano , Julie K.S. Hsu , Y. Summers , R. Peck , L. Pemberton , P. Yeates , S. Ray , P. Taylor

{"title":"Platypnea-orthodeoxia syndrome following left pneumonectomy for early stage non-small cell lung cancer","authors":"R. Califano , Julie K.S. Hsu , Y. Summers , R. Peck , L. Pemberton , P. Yeates , S. Ray , P. Taylor","doi":"10.1016/j.ctrc.2013.09.001","DOIUrl":"10.1016/j.ctrc.2013.09.001","url":null,"abstract":"<div><h3>Introduction</h3><p>Lobectomy or pneumonectomy represents the treatment of choice for resectable early stage non-small cell lung cancer (NSCLC). The location of heart and great vessels, liver and spleen changes considerably following pneumonectomy as a consequence of mediastinal shift and elevation of the hemidiaphragm.</p></div><div><h3>Presentation of case</h3><p>A 70 years old gentleman developed acute shortness of breath two months after undergoing a left pneumonectomy for a pT2pN1M0 NSCLC, squamous cell carcinoma. His dyspnea and oxygen saturation worsened when sitting upright and immediately improved when he assumed the supine position, consistent with platypnea-orthodeoxia syndrome, and suggesting a potential inter-atrial right-to-left shunt. The presence of a patent foramen ovale (PFO) was documented by transoesophageal echocardiography. The patient underwent percutaneous closure of the PFO which markedly reduced the shunt, and led to resolution of symptoms.</p></div><div><h3>Discussion</h3><p>PFO is a common anomaly, found in approximately 25% of adults. Its presence is associated with increased risk of stroke from paradoxical emboli. Inter-atrial shunting after major thoracic surgery is a rare but clinically significant event. The case here reported was diagnosed following left pneumonectomy and to our knowledge, only two other single cases of PFO after left pneumonectomy have been reported in the literature so far.</p></div><div><h3>Conclusion</h3><p>A PFO should always be considered in the differentials for patients presenting with platypnea-orthodeoxia syndrome after lung surgery. Given the high risk of embolic stroke and high success rate of transcatheter percutaneous closure, these patients should be promptly referred for cardiac investigations and appropriate management.</p></div>","PeriodicalId":90461,"journal":{"name":"Cancer treatment communications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ctrc.2013.09.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54049590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Non-Hodgkin's lymphoma presenting as an isolated chest wall tumour 非霍奇金淋巴瘤表现为孤立的胸壁肿瘤

Cancer treatment communications Pub Date : 2013-01-01 DOI: 10.1016/j.ctrc.2013.04.001

Nikhil Gupta , Niladhar S. Hadke , Nita Khurana

引用次数: 2