Biometrics & biostatistics international journal最新文献_第10页

Stress causes and outcomes statistical analysis 应激原因及结果的统计分析

Biometrics & biostatistics international journal Pub Date : 2018-08-15 DOI: 10.15406/bbij.2018.07.00229

S. Kadry, Maryam Kbaysi, Suhad Al-Safadi, Dareen Al-Bakri

引用次数: 1

The molecular evolution of amylase duplicates genes in D. melanogaster group 黑腹龙类群淀粉酶重复基因的分子进化

Biometrics & biostatistics international journal Pub Date : 2018-08-11 DOI: 10.15406/BBIJ.2018.07.00236

Sammer M Marzouk

{"title":"The molecular evolution of amylase duplicates genes in D. melanogaster group","authors":"Sammer M Marzouk","doi":"10.15406/BBIJ.2018.07.00236","DOIUrl":"https://doi.org/10.15406/BBIJ.2018.07.00236","url":null,"abstract":"Drosophila melanogaster is a species of fly in the family Drosophilidae. The alpha–amylase system of Drosophila is one of the most intensively examined systems of genes in the field of evolutionary research. Alpha–amylase (EC 3.2.1.1, alpha–1,4– glucan–4–glucanohydrolase) is a digestive enzyme. Its role in the digestive process is to break down starch into glucose and maltose to produce energy. There are six major and minor isozymes of amylase that have been recorded in natural populations of D. melanogaster (Inomata & Yamazaki T).1 Amylase activity is repressed by its produce, glucose, and maltose. It is induced by the substrate starch. Population genetic surveys provide information about the molecular characterization of fitness–related genes upon which natural selection acts. Differences in activity levels and the inducibility has been recorded within and between species. This variation is caused because of a mRNA abundance. However, the difference in the catalytic efficiency of an individual izozymer contributes to the recorded differences in activity between and within species. In addition to the differences in inducibility, differences in developmental and organ– specific expression have been recorded Popadić et al.2","PeriodicalId":90455,"journal":{"name":"Biometrics & biostatistics international journal","volume":"59 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87750466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Some combinatorial structures in experimental design: overview, statistical models and applications 实验设计中的一些组合结构:综述、统计模型及其应用

Biometrics & biostatistics international journal Pub Date : 2018-08-10 DOI: 10.15406/BBIJ.2018.07.00228

P. Valcheva, T. Oliveira

引用次数: 0

Effects of the PNPLA3–SNP rs738409 on Serum Transaminase levels are modified by body mass index and alcohol consumption PNPLA3-SNP rs738409对血清转氨酶水平的影响受体重指数和饮酒的影响

Biometrics & biostatistics international journal Pub Date : 2018-08-08 DOI: 10.15406/bbij.2018.07.00227

P. Meffert, J. Kühn, Baumeister Se, M. Lerch, J. Mayerle, H. Völzke

{"title":"Effects of the PNPLA3–SNP rs738409 on Serum Transaminase levels are modified by body mass index and alcohol consumption","authors":"P. Meffert, J. Kühn, Baumeister Se, M. Lerch, J. Mayerle, H. Völzke","doi":"10.15406/bbij.2018.07.00227","DOIUrl":"https://doi.org/10.15406/bbij.2018.07.00227","url":null,"abstract":"For the common rs738409 C>G SNP, which is located in the patatin-like phospholipase domain-containing protein 3 (PNPLA3), a strong association between non-alcoholic fatty liver disease (NAFLD) has been detected [1], approved [2-8] and expanded to an association with liver-fat content in general [8-13] and serum transaminase levels [14]. Also an association to a higher risk of progression to cirrhosis in NAFLD patients has been shown [15]. Transaminase levels, particularly of alanine transaminase (ALT) and aspartate transaminase (AST), are strong indicators of hepatic steatosis [16] as well as of cardio-metabolic risks [17] and are associated with mortality even within their reference ranges [18]. Yet, a small number of studies reported gene-environment interactions for rs738409. Recently it has been shown that the G allele of rs738409 is associated with lower serum triglyceride and cholesterol levels and higher ALT levels in overweight individuals only [19]. Children with the minor G allele had more liver fat per unit omega-fat intake than major homozygous children [20]. In another study, sugar and carbohydrate intake in Hispanic children was positively related to hepatic fat fraction in GG carriers but not in CG and CC carriers [21].","PeriodicalId":90455,"journal":{"name":"Biometrics & biostatistics international journal","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72788730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hemoglobin levels in pregnant women and its outcomes 孕妇血红蛋白水平及其结果

Biometrics & biostatistics international journal Pub Date : 2018-08-06 DOI: 10.15406/bbij.2018.07.00226

S. Kadry, Carla Sleem, R. A. Samad

引用次数: 9

The investigation of Pneumocystis jirovecii colonization in adult individuals of Turkish population 土耳其成年人群吉氏肺囊虫定殖情况调查

Biometrics & biostatistics international journal Pub Date : 2018-07-31 DOI: 10.15406/BBIJ.2018.07.00223

I. Qoraan, Y. Oz, M. Metintaş, G. Durmaz

{"title":"The investigation of Pneumocystis jirovecii colonization in adult individuals of Turkish population","authors":"I. Qoraan, Y. Oz, M. Metintaş, G. Durmaz","doi":"10.15406/BBIJ.2018.07.00223","DOIUrl":"https://doi.org/10.15406/BBIJ.2018.07.00223","url":null,"abstract":"Pneumocystis jirovecii previously known Pneumocystis carinii is the cause of opportunistic infections in the lower respiratory tract of immunocompromised hosts mainly among patients with HIV infected, hematologic malignancies, congenital immunodeficiency, organ transplant recipients, and patients receiving immunosuppressive drugs.1 The organism was considered as one of the most leading causes of morbidity and mortality among HIV patients before the introduction of antiretroviral therapy. However, Pneumocystis pneumonia (PCP) is associated with significant mortality and morbidity rates among non-HIV patients.2 The mechanism of Pneumocystis transmission was debating. Although previously it was thought that PCP infection is a reactivation of latent infection acquired during childhood, recently it has been recognized to be de novo exposure from either environment or individuals with PCP or colonized with Pneumocystis.3 Pneumocystis colonization has been defined as the presence of P. jirovecii in respiratory specimens of persons without signs or symptoms of acute pneumonia3 Pneumocystis jirovecii can colonize in lower respiratory tract without causing signs and symptoms and PCP may develop in these colonized individuals. Thus, Pneumocystis colonized individuals could also be a problem for public health since they could play a role as a major reservoir of Pneumocystis jirovecii and a source of infection for susceptible subjects.4 Furthermore, patients at risk for PCP who receive long term anti-pneumocystis prophylactic treatments may be colonized with drug mutated pneumocystis species. In addition, colonization may stimulate a host inflammatory response leading to lung damage and progression of lung disease such as chronic obstructive pulmonary disease (COPD).1,3 Therefore, we planned a prospective study and aimed to investigate the colonization prevalence and related risk factors among adult population in our region.","PeriodicalId":90455,"journal":{"name":"Biometrics & biostatistics international journal","volume":"46 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87015447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

A Bayesian single-arm design using predictive probability monitoring 基于预测概率监测的贝叶斯单臂设计

Biometrics & biostatistics international journal Pub Date : 2018-07-26 DOI: 10.15406/bbij.2018.07.00222

Patrick D Mitchell

引用次数: 1

On circular systematic sampling in the presence of linear trend 线性趋势下的循环系统抽样

Biometrics & biostatistics international journal Pub Date : 2018-07-20 DOI: 10.15406/bbij.2018.07.00220

S. J.

引用次数: 1

Determination of parametric average code length of inaccuracy measure 误差测量参数平均码长的确定

Biometrics & biostatistics international journal Pub Date : 2018-07-19 DOI: 10.15406/BBIJ.2018.07.00219

Arif Habib

{"title":"Determination of parametric average code length of inaccuracy measure","authors":"Arif Habib","doi":"10.15406/BBIJ.2018.07.00219","DOIUrl":"https://doi.org/10.15406/BBIJ.2018.07.00219","url":null,"abstract":"From past three decades, entropy which is branch of statistical sciences has been used to determine the degree of variability, describes how uncertainty should be quantified in a skillful manner for representation. Statistical entropy has some conflicting explanations so that sometimes it measures two complementary conceptions like information and lack of information. Claude Shannon through two outstanding contributions in 1948 and 1949 relates it with positive information. These were followed by a flood of research papers hypothesize upon the possible applications in almost every field such as pure mathematics, semantics, physics, management, thermodynamics, botany, econometrics, operations research, psychology, epidemiological studies, disease management and related disciplines. Information theory has also had an important role in shaping theories of perception, cognition, and neural computation. When the message is readily measurable, we can say that the information is the reduction of uncertainty. But we usually encountered lossy information i.e a part of the transmitted information reaches the destination in a distorted form. In statistical theory of information, certain specialized terms which need to be translated into a measurable form. A source is similar to the space of a random experiment. A finite sequence of characters is called a word in the same way that the sequence of a number of outcomes associated with the repetition of an experiment may be designated as an event. An interesting observation can be made about the entropy of a binary source. Binary coding offers an interesting practical opportunity for encoding.","PeriodicalId":90455,"journal":{"name":"Biometrics & biostatistics international journal","volume":"57 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84762434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Item response theory-based validation of Taiwanese patient safety culture measurement instrument 基于项目反应理论的台湾患者安全文化测量仪验证

Biometrics & biostatistics international journal Pub Date : 2018-07-16 DOI: 10.15406/BBIJ.2018.07.00218

Wui-Chiang Lee, Heon-Jae Jeong, H. Liao, Cheng-Fan Wen, Pa-Chun Wang

引用次数: 2