International journal of experimental and computational biomechanics最新文献_第2页

Non-Newtonian blood flow and coupled blood-wall oxygen mass transport in a 180° curved artery 180°弯曲动脉的非牛顿血流和耦合血壁氧质量运输

International journal of experimental and computational biomechanics Pub Date : 2018-06-14 DOI: 10.1504/IJECB.2018.10013555

M. Raoufi, H. Niazmand, M. Pourramezan

引用次数: 0

Particle dispersion in morphologically-inspired computational models of alveolar capillary networks 肺泡毛细血管网络形态学启发计算模型中的粒子分散

International journal of experimental and computational biomechanics Pub Date : 2016-02-17 DOI: 10.1504/ijecb.2015.074733

H. Stauber, Rami Fishler, Philipp Hofemeier, D. Waisman, J. Sznitman

{"title":"Particle dispersion in morphologically-inspired computational models of alveolar capillary networks","authors":"H. Stauber, Rami Fishler, Philipp Hofemeier, D. Waisman, J. Sznitman","doi":"10.1504/ijecb.2015.074733","DOIUrl":"https://doi.org/10.1504/ijecb.2015.074733","url":null,"abstract":"With growing evidence of the ability of inhaled nanoparticles (NP) to translocate from the lungs into the pulmonary circulation, increased concerns regarding the fate of such particles reaching body organs have risen. Until present, there is still a limited understanding on the transport dynamics of NPs following translocation into the pulmonary microcirculation. To gain initial insight into such processes, simulations of the transport and dispersion of various particle sizes are conducted in anatomically-inspired alveolar capillary networks (ACN). Our models, based on the seminal 'sheet flow' model, investigate quantitatively the influence of network porosity on particle dynamics. For fixed flow conditions, we find that the effective dispersion coefficient is sensibly enhanced with decreasing porosity levels and decreasing particle sizes. Furthermore, particle size significantly influences the characteristics of particle spreading and tortuosity. Overall, our findings represent a tangible first step in further understanding inhaled NP transport in networks representative of the alveolar capillaries.","PeriodicalId":90184,"journal":{"name":"International journal of experimental and computational biomechanics","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1504/ijecb.2015.074733","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66745454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Characterisation of the nonlinear elastic behaviour of guinea pig tympanic membrane using micro-fringe projection 用微条纹投影法表征豚鼠鼓膜的非线性弹性行为

International journal of experimental and computational biomechanics Pub Date : 2016-02-17 DOI: 10.1504/ijecb.2015.074740

Junfeng Liang, B. Fu, Huiyang Luo, Don U. Nakmali, R. Gan, Hongbing Lu

{"title":"Characterisation of the nonlinear elastic behaviour of guinea pig tympanic membrane using micro-fringe projection","authors":"Junfeng Liang, B. Fu, Huiyang Luo, Don U. Nakmali, R. Gan, Hongbing Lu","doi":"10.1504/ijecb.2015.074740","DOIUrl":"https://doi.org/10.1504/ijecb.2015.074740","url":null,"abstract":"Mechanical properties of tympanic membrane (TM) are crucial inputs for modelling acoustic transmission through the ear. In this paper a combined experimental and numerical approach was used to determine the mechanical properties of guinea pig TM under quasi-static condition based on the response of the TM to static pressure. A guinea pig bulla was prepared and the intact TM was subjected to both positive and negative pressures while its topography was measured using the micro-fringe projection technique. Images of the deformed TM were acquired and processed with a phase-shift method to reconstruct the surface profile and determine the volume deformation of the TM under pressures. Finite element method with the implementation of a hyperelastic model was established. The simulated TM deformations under applied pressures demonstrated a good agreement with the measured curves of the pressure-volume displacement relationship. The Young's modulus of guinea pig TM from seven bullas was determined as 15.2-28.3 MP...","PeriodicalId":90184,"journal":{"name":"International journal of experimental and computational biomechanics","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1504/ijecb.2015.074740","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66745473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Modelling and impact analysis of football player head with helmet toward mitigating brain concussion 橄榄球运动员头部戴头盔对减轻脑震荡的建模与冲击分析

International journal of experimental and computational biomechanics Pub Date : 2016-02-17 DOI: 10.1504/ijecb.2015.074732

Peyman Honarmandi, A. Sadegh, P. Cavallaro

{"title":"Modelling and impact analysis of football player head with helmet toward mitigating brain concussion","authors":"Peyman Honarmandi, A. Sadegh, P. Cavallaro","doi":"10.1504/ijecb.2015.074732","DOIUrl":"https://doi.org/10.1504/ijecb.2015.074732","url":null,"abstract":"In recent years, increasing concussions among American football players have drawn attention and concerns regarding safety of today's football helmets. This study investigates the effects of concussive impact forces on the brain of football players and the shock absorbing performance of actual football helmets. Initially, the mechanical properties of typical helmet materials were obtained through compression tests and hysteresis loop experiments. Next, a lumped-mass model was developed to physically describe both the head and helmet together against an impact load, and the brain response was obtained from the semi-analytical analysis. To extract more information such as strains and wave propagations within the brain, a detailed continuum model was constructed and the response of the brain was analysed by using the finite element method. A realistic impact load was obtained from a case study of actual football play. Our experimental data along with biomechanical data of the head and brain from the available literature were incorporated into our modelling and analyses. The results indicated that the accelerations and strains in the brain were both above the concussion thresholds and that current football helmet designs may not protect players against concussion.","PeriodicalId":90184,"journal":{"name":"International journal of experimental and computational biomechanics","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1504/ijecb.2015.074732","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66745405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Numerical modelling and analytical analysis of Shore OO hardness tests on soft materials 软质材料邵氏OO硬度试验的数值模拟与分析

International journal of experimental and computational biomechanics Pub Date : 2016-01-01 DOI: 10.1504/IJECB.2016.10002676

Hongyi Zhao, Shudong Li, Lisa Li, G. Rothwell, James Ren

引用次数: 1

Role of helmets in blast mitigation: insights from experiments on PMHS surrogate 头盔在减缓爆炸中的作用:来自PMHS替代物实验的见解

International journal of experimental and computational biomechanics Pub Date : 2016-01-01 DOI: 10.1504/IJECB.2016.10002680

S. Ganpule, R. Salzar, B. Perry, N. Chandra

{"title":"Role of helmets in blast mitigation: insights from experiments on PMHS surrogate","authors":"S. Ganpule, R. Salzar, B. Perry, N. Chandra","doi":"10.1504/IJECB.2016.10002680","DOIUrl":"https://doi.org/10.1504/IJECB.2016.10002680","url":null,"abstract":"Blast induced traumatic brain injury (bTBI) has emerged as the most significant injury to war fighters in recent conflicts. Interaction of the blast wave with the head and helmet are not well understood. In this work, the effects of blast were investigated on the post-mortem human subject (PMHS) head using a compression driven shock tube. The results suggest that the evolution of intracranial pressure profiles is strongly governed by the wave propagation through skin-skull-brain parenchyma. It is also observed that the sinus cavities naturally attenuate the blast overpressure. Performance of two helmet configurations (padded and suspension) in mitigating the blast is also evaluated. The results suggest that the amount of mitigation offered by each helmet varies with the helmet configuration. For helmets with the suspension system, the blast wave is intensified beneath the helmet. Further, the degree of blast wave mitigation is affected by the morphology of the PMHS itself. Overall, these results suggest that the blast wave interacts with the head and the helmet in a complex manner and these interaction effects must be taken into account while designing strategies for protection of the head against the blast.","PeriodicalId":90184,"journal":{"name":"International journal of experimental and computational biomechanics","volume":"4 1","pages":"13"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66745530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

How does the material variation of dynamic hip screw affect the cut-out risk in the treatment of intertrochanteric femoral fractures? 动力髋螺钉的材质变化如何影响股骨粗隆间骨折的切开风险?

International journal of experimental and computational biomechanics Pub Date : 2016-01-01 DOI: 10.1504/IJECB.2016.10002682

Talip Çelik, İ. Mutlu, A. Özkan, Y. Kişioğlu

引用次数: 0

The effect of shock waves on brain blood pressure; experimental and computational studies 冲击波对脑血压的影响;实验与计算研究

International journal of experimental and computational biomechanics Pub Date : 2016-01-01 DOI: 10.1504/IJECB.2016.10002687

S. Hashemi, Douglas Jahnke, A. Sadegh, Y. Andreopoulos

引用次数: 0

Predicting pressure distribution between transfemoral prosthetic socket and residual limb using finite element analysis 利用有限元分析预测经股义肢窝与残肢之间的压力分布

International journal of experimental and computational biomechanics Pub Date : 2016-01-01 DOI: 10.1504/IJECB.2016.10002681

Rajesh Surapureddy, A. Schonning, S. Stagon, A. Kassab

引用次数: 12

Finite element simulation of intra-carpal tunnel pressure: the effects of individual finger flexion and histological changes 腕管内压力的有限元模拟:个体手指屈曲和组织学变化的影响

International journal of experimental and computational biomechanics Pub Date : 2015-12-31 DOI: 10.1504/ijecb.2015.073929

Kyrin Liong, A. Lahiri, Shujin Lee, D. Chia, A. Biswas, H. Lee

{"title":"Finite element simulation of intra-carpal tunnel pressure: the effects of individual finger flexion and histological changes","authors":"Kyrin Liong, A. Lahiri, Shujin Lee, D. Chia, A. Biswas, H. Lee","doi":"10.1504/ijecb.2015.073929","DOIUrl":"https://doi.org/10.1504/ijecb.2015.073929","url":null,"abstract":"Carpal tunnel syndrome (CTS) is a common neuropathy, yet its etiology is unknown. While repetitive finger flexion and interstitial subsynovial connective tissue (SSCT) thickening are commonly associated with idiopathic CTS development, the stress that the nerve experiences remain unexamined. In this study, a patient-specific computational model of the carpal tunnel was developed. Tendon displacements corresponding to thumb, index finger (IF) and middle finger (MF) flexion were prescribed. To replicate a CTS candidate, the most common physiological finding - fibrosis of the SSCT - was modelled. Heightened nerve coefficients were also prescribed to simulate nerve stiffening. This revealed that volarly-moving tendons, as in IF and thumb flexion, elicit greater nerve stresses than those dorsally-moving tendons, as in MF flexion. The stress encountered in CTS candidates significantly exceeded those in normal candidates, demonstrating that tendon path, and the in-vivo conditions of an individual's SSCT and median nerve stiffness predominantly affect nerve stress.","PeriodicalId":90184,"journal":{"name":"International journal of experimental and computational biomechanics","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2015-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1504/ijecb.2015.073929","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66745338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1