Audiology and neurotology. Extra最新文献

Dietary Supplement Comprised of β-Carotene, Vitamin C, Vitamin E, and Magnesium: Failure to Prevent Music-Induced Temporary Threshold Shift 由β-胡萝卜素、维生素C、维生素E和镁组成的膳食补充剂:无法防止音乐引起的暂时阈值转移

Audiology and neurotology. Extra Pub Date : 2016-05-01 DOI: 10.1159/000446600

C. L. Le Prell, Angela N Fulbright, C. Spankovich, S. Griffiths, E. Lobarinas, K. Campbell, P. Antonelli, G. E. Green, K. Guire, Josef M. Miller

引用次数: 23

The Expression of TNFα, IL-6, IL-2 and IL-8 in the Serum of Patients with Idiopathic Sudden Sensorineural Hearing Loss: Possible Prognostic Factors of Response to Corticosteroid Treatment 特发性突发性感音神经性听力损失患者血清中TNFα、IL-6、IL-2和IL-8的表达:对皮质类固醇治疗反应的可能预后因素

Audiology and neurotology. Extra Pub Date : 2016-04-05 DOI: 10.1159/000442016

Z. Tsinaslanidou, M. Tsaligopoulos, N. Angouridakis, V. Vital, G. Kekes, J. Constantinidis

{"title":"The Expression of TNFα, IL-6, IL-2 and IL-8 in the Serum of Patients with Idiopathic Sudden Sensorineural Hearing Loss: Possible Prognostic Factors of Response to Corticosteroid Treatment","authors":"Z. Tsinaslanidou, M. Tsaligopoulos, N. Angouridakis, V. Vital, G. Kekes, J. Constantinidis","doi":"10.1159/000442016","DOIUrl":"https://doi.org/10.1159/000442016","url":null,"abstract":"Introduction: Idiopathic sudden sensorineural hearing loss (ISSNHL) remains one of the major unsolved otologic emergencies. A viral infection, a systemic inflammatory disorder, as well as physical, mental and metabolic stress can trigger an innate immune response in the inner ear resulting in ISSNHL. Proinflammatory cytokines play a central role in this cochlear immunological cascade. Objective: To examine the expression of proinflammatory cytokines in the serum of patients with ISSNHL in correlation with the therapeutic outcome of intravenous administration of corticosteroids. Method: Forty-three patients primarily diagnosed with ISSNHL underwent intravenous corticosteroid treatment for 8 days. The expression of tumor necrosis factor-α (TNFα), interleukin-6 (IL-6), interleukin-2 (IL-2) and interleukin-8 (IL-8) was detected with the use of enzyme-linked immunosorbent assay in serum specimens on the 1st and 8th day of treatment and it was correlated with the treatment outcome. Results: TNFα reduction and IL-6 increase strongly correlate with a good therapeutic result [χ2(2) = 13.12, p = 0.001 and χ2(2) = 16.78, p = 0.0001]. IL-8 increase reflects negatively on the outcome, however, not in a statistically significant way. No association was established between IL-2 variations and the therapeutic outcome. Conclusions: TNFα and IL-6 can be used as prognostic factors for the treatment outcome, whereas the prognostic value of IL-8 requires further statistical confirmation.","PeriodicalId":90109,"journal":{"name":"Audiology and neurotology. Extra","volume":"6 1","pages":"9 - 19"},"PeriodicalIF":0.0,"publicationDate":"2016-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000442016","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64962563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13

Effects of Round Window Opening Size and Moisturized Electrodes on Intracochlear Pressure Related to the Insertion of a Cochlear Implant Electrode 圆窗开口大小和湿润电极对植入人工耳蜗电极后耳蜗内压力的影响

Audiology and neurotology. Extra Pub Date : 2016-02-23 DOI: 10.1159/000442515

I. Todt, A. Ernst, P. Mittmann

引用次数: 19

Validation of the U-STARR with the AB-York Crescent of Sound, a New Instrument to Evaluate Speech Intelligibility in Noise and Spatial Hearing Skills 基于AB-York新月声的U-STARR的验证——一种评估噪声和空间听力技能语音可理解性的新仪器

Audiology and neurotology. Extra Pub Date : 2015-02-10 DOI: 10.1159/000370300

Y. Smulders, A. B. Rinia, V. Pourier, A. van Zon, G. A. van Zanten, I. Stegeman, Fanny Scherf, A. Smit, V. Topsakal, R. Tange, W. Grolman

{"title":"Validation of the U-STARR with the AB-York Crescent of Sound, a New Instrument to Evaluate Speech Intelligibility in Noise and Spatial Hearing Skills","authors":"Y. Smulders, A. B. Rinia, V. Pourier, A. van Zon, G. A. van Zanten, I. Stegeman, Fanny Scherf, A. Smit, V. Topsakal, R. Tange, W. Grolman","doi":"10.1159/000370300","DOIUrl":"https://doi.org/10.1159/000370300","url":null,"abstract":"The Advanced Bionics® (AB)-York crescent of sound is a new test setup that comprises speech intelligibility in noise and localization tests that represent everyday listening situations. One of its tests is the Sentence Test with Adaptive Randomized Roving levels (STARR) with sentences and noise both presented from straight ahead. For the Dutch population, we adopted the AB-York setup and replaced the English sentences with a validated set of Dutch sentences. The Dutch version of the STARR is called the Utrecht-STARR (U-STARR). This study primarily assesses the validity and reliability of the U-STARR compared to the Plomp test, which is the current Dutch gold standard for speech-in-noise testing. The outcome of both tests is a speech reception threshold in noise (SRTn). Secondary outcomes are the SRTn measured with sounds from spatially separated sources (SISSS) as well as sound localization capability. We tested 29 normal-hearing adults and 18 postlingually deafened adult patients with unilateral cochlear implants (CI). This study shows that the U-STARR is adequate and reliable and seems better suited for severely hearing-impaired persons than the conventional Plomp test. Further, CI patients have poor spatial listening skills, as demonstrated with the AB-York test.","PeriodicalId":90109,"journal":{"name":"Audiology and neurotology. Extra","volume":"5 1","pages":"1 - 10"},"PeriodicalIF":0.0,"publicationDate":"2015-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000370300","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64762081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Evaluation of Bone Tissue Formation in a Flat Surface Attachment of a Bone Conduction Implant: A Pilot Study in a Sheep Model 评价骨传导植入物在平面附着中的骨组织形成:绵羊模型的初步研究

Audiology and neurotology. Extra Pub Date : 2014-12-01 DOI: 10.1159/000369918

Måns Eeg-Olofsson, A. Lith, B. Håkansson, Sabine Reinfeldt, H. Taghavi, Karl-Johan Fredén Jansson, C. Johansson

{"title":"Evaluation of Bone Tissue Formation in a Flat Surface Attachment of a Bone Conduction Implant: A Pilot Study in a Sheep Model","authors":"Måns Eeg-Olofsson, A. Lith, B. Håkansson, Sabine Reinfeldt, H. Taghavi, Karl-Johan Fredén Jansson, C. Johansson","doi":"10.1159/000369918","DOIUrl":"https://doi.org/10.1159/000369918","url":null,"abstract":"The bone conduction implant (BCI) is a new bone conduction hearing device implanted under intact skin. The transducer has a flat direct contact with the mastoid part of the temporal bone, and no screws are used. The sound signal is transmitted from the external audio processor to the implant by means of magnetic induction. In this study, osseointegration of a flat passive BCI transducer dummy in sheep skulls was assessed using quantitative and qualitative histology as well as cone beam computed tomography (CBCT) and computed tomography (CT). The histology results were also related to the mechanical properties of the bone-to-implant interface. Eight months after the surgical implantation, histology sections of the bone close to the implant showed bone remodeling, compact bone and osseointegration. The histological findings corresponded well to the mechanical measurements indicating stiffer bone close to the implant and unaffected skull vibration transmission. Neither CBCT nor CT had enough resolution to visualize the bone-to-implant interface in detail. In this study, using an animal model, it is shown that a flat implant in contact with bone can be a feasible method for efficient vibration transmission to the skull bone.","PeriodicalId":90109,"journal":{"name":"Audiology and neurotology. Extra","volume":"4 1","pages":"62 - 76"},"PeriodicalIF":0.0,"publicationDate":"2014-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000369918","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64759001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Electromagnetic Compatibility of Cochlear Implant with an Aircraft Cockpit 人工耳蜗与飞机座舱的电磁兼容性

Audiology and neurotology. Extra Pub Date : 2014-08-16 DOI: 10.1159/000365835

Juliana Maria Araujo Caldeira, F. D. de Almeida, Marcos Antônio Ribeiro, Jana D'Arc Abdalla Alonso, Maria Valéria Schmidt Goffi-Gomez, R. Bento

引用次数: 1

Experiences and Results from Cochlear Implantation in Patients with Long Duration of Deafness 长期耳聋患者人工耳蜗植入术的经验与效果

Audiology and neurotology. Extra Pub Date : 2014-08-08 DOI: 10.1159/000365274

Karin Lundin, Fredrik Stillesjö, H. Rask-Andersen

引用次数: 13

Clinical and Microbiological Evaluation of an Extended-Wear Hearing Instrument 一种增戴式助听器的临床和微生物学评价

Audiology and neurotology. Extra Pub Date : 2014-06-11 DOI: 10.1159/000363213

J. Sim, You-Zhou Xie, E. Karamuk, Alexander von Kameke, J. T. Holder, R. Zbinden, C. Röösli, A. Huber

{"title":"Clinical and Microbiological Evaluation of an Extended-Wear Hearing Instrument","authors":"J. Sim, You-Zhou Xie, E. Karamuk, Alexander von Kameke, J. T. Holder, R. Zbinden, C. Röösli, A. Huber","doi":"10.1159/000363213","DOIUrl":"https://doi.org/10.1159/000363213","url":null,"abstract":"This study aimed to examine the integrity of the ear canal skin and its microbiological changes caused by an extended-wear hearing device. An extended-wear hearing device, Lyric2 (Phonak AG, Switzerland), which is the second generation of the Lyric device, was fitted to 52 ears of 27 subjects. A refit of the device was done for a selection of ears (n = 15) for which the initial fitting was interrupted (28 ears). A matching control group consisted of 10 ears of 10 subjects with no history of using any form of hearing aid for 3 months. The ear canal skin of ears fitted with the hearing device was inspected using an otoendoscope, and signs of problematic pathological conditions were graded. Microbiological examinations were performed at three different stages following fitting. Wearing the device was interrupted in 28 (53.8%) out of the 52 ears for the initial fitting, and 17 of the 28 interrupted cases (60.7%) were due to issues of the ear canal skin. In 3 of 15 ears (25%) following a refitting, wearing the device was interrupted yet again, and 1 of these 3 interruptions was caused by ear canal skin pathologies. Growth of bacteria was not enhanced or prompted by wearing the Lyric2, and Gram-negative bacteria could not be cultured while the device was in place. Based on aspects of ear canal skin pathology, continuous and nonproblematic uses of the Lyric2 device are presumed to be obtained if the fitting is done carefully. Wearing of the Lyric2 device can be considered safe from a microbiological perspective and does not promote growth of Gram-negative bacteria.","PeriodicalId":90109,"journal":{"name":"Audiology and neurotology. Extra","volume":"4 1","pages":"32 - 45"},"PeriodicalIF":0.0,"publicationDate":"2014-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000363213","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64722354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Factors Contributing to Postural Sway in Patients with Diabetes in an In-Hospital Education Program 在医院教育项目中影响糖尿病患者体位摇摆的因素

Audiology and neurotology. Extra Pub Date : 2014-05-21 DOI: 10.1159/000362753

Satofumi Sugimoto, Yukari Fukunaga, N. Katayama, Tadao Yoshida, M. Teranishi, Saiko Sugiura, Y. Uchida, H. Kamiya, Y. Oiso, T. Nakashima

{"title":"Factors Contributing to Postural Sway in Patients with Diabetes in an In-Hospital Education Program","authors":"Satofumi Sugimoto, Yukari Fukunaga, N. Katayama, Tadao Yoshida, M. Teranishi, Saiko Sugiura, Y. Uchida, H. Kamiya, Y. Oiso, T. Nakashima","doi":"10.1159/000362753","DOIUrl":"https://doi.org/10.1159/000362753","url":null,"abstract":"Objective: We investigated the effect of polyneuropathy, nephropathy, and retinopathy on postural sway in patients with poorly controlled diabetes mellitus (DM) who were hospitalized for DM education. We also investigated the relationship between postural sway and hearing disturbances. Methods: We included 50 subjects who were hospitalized for the purpose of DM education. Mean age was 57.2 years, mean HbA1c was 9.4%, and mean DM duration was 11.1 years. Renal function, retina condition, and nerve conduction were evaluated in relation to DM complications (nephropathy, retinopathy, and neuropathy). Static posturography was performed to assess DM-related postural sway. Nerve conduction studies were used to obtain information on the condition of peripheral nerves. Pure-tone audiometry was measured. Stepwise multiple linear regression was used to assess DM-related factors that affected postural sway. Results: Deterioration of median nerve compound muscle action potential (CMAP) amplitude, tibial nerve CMAP conduction velocity, and peroneal nerve CMAP latency were associated with deterioration of postural sway. Deterioration of hearing in the worse ear was also associated with postural sway. Conclusion: In patients with poorly controlled DM, postural sway was particularly associated with deterioration of motor nerve conduction study parameters represented by median nerve CMAP amplitude, tibial nerve CMAP conduction velocity, and peroneal nerve CMAP latency. A link between diabetic polyneuropathy, diabetes-related postural sway, and diabetes-related hearing loss was recognized.","PeriodicalId":90109,"journal":{"name":"Audiology and neurotology. Extra","volume":"4 1","pages":"23 - 31"},"PeriodicalIF":0.0,"publicationDate":"2014-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000362753","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64719255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Auditory Steady-State Response in the First Six Months of Life 生命前六个月的听觉稳态反应

Audiology and neurotology. Extra Pub Date : 2014-03-01 DOI: 10.1159/000356232

Luciana Cristina Oliveira, K. F. Alvarenga, E. Araújo, M. Salgado, Orozimbo Alves Costa Filho

引用次数: 0