Proceedings ... International Conference on MEMS, NANO, and Smart Systems. International Conference on MEMS, NANO, and Smart Systems最新文献

{"title":"Development of miniature visual monitoring cameras at OIP","authors":"L. D. Vos, N. V. Vooren","doi":"10.1109/ICMENS.2005.41","DOIUrl":"https://doi.org/10.1109/ICMENS.2005.41","url":null,"abstract":"This paper describes small modular cameras for space applications, which have been developed by OIP Sensor Systems. These cameras are based on CMOS Active Pixel Sensors (APS) developed by FillFactory. The \"Visual Monitoring Cameras\" (VMC) are mostly developed under ESA contracts and are used for observing the deployment of mechanisms such as solar panels and antennas on board satellites. The VMC cameras are also suitable for monitoring the separation phases of satellites and landers from their spacecraft, by means of a sequence of snap shot images. Numerous VMC cameras have been successfully launched on the XMM satellite, CLUSTER II, PROBA, ARIANE V and the MARS-EXPRESS mission. In this paper the design of the VMC cameras, that have been developed, are described, and possible future developments are discussed.","PeriodicalId":90041,"journal":{"name":"Proceedings ... International Conference on MEMS, NANO, and Smart Systems. International Conference on MEMS, NANO, and Smart Systems","volume":"1 1","pages":"135-136"},"PeriodicalIF":0.0,"publicationDate":"2005-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83263411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A High-Voltage Integrated Circuit Engine for a Dielectrophoresis-based Programmable Micro-Fluidic Processor.","authors":"K Wayne Current, Kelvin Yuk, Charles McConaghy, Peter R C Gascoyne, Jon A Schwartz, Jody V Vykoukal, Craig Andrews","doi":"10.1109/ICMENS.2005.15","DOIUrl":"10.1109/ICMENS.2005.15","url":null,"abstract":"<p><p>A high-voltage (HV) integrated circuit has been demonstrated to transport droplets on programmable paths across its coated surface. This chip is the engine for a dielectrophoresis (DEP)-based micro-fluidic lab-on-a-chip system. This chip creates DEP forces that move and help inject droplets. Electrode excitation voltage and frequency are variable. With the electrodes driven with a 100V peak-to-peak periodic waveform, the maximum high-voltage electrode waveform frequency is about 200Hz. Data communication rate is variable up to 250kHz. This demonstration chip has a 32×32 array of nominally 100V electrode drivers. It is fabricated in a 130V SOI CMOS fabrication technology, dissipates a maximum of 1.87W, and is about 10.4 mm × 8.2 mm.</p>","PeriodicalId":90041,"journal":{"name":"Proceedings ... International Conference on MEMS, NANO, and Smart Systems. International Conference on MEMS, NANO, and Smart Systems","volume":" ","pages":"153-158"},"PeriodicalIF":0.0,"publicationDate":"2005-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3754896/pdf/nihms106079.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31693733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tailored Nanomaterials Systems Based on Artificial Design and Fabrication: An Overview of the Synthetic Nanofunction Materials Project","authors":"H. Yokoyama","doi":"10.1109/ICMENS.2004.139","DOIUrl":"https://doi.org/10.1109/ICMENS.2004.139","url":null,"abstract":"One of the most attractive and challenging features of materials research on the nanometer scale is the possibility to rationally design and fabricate novel functionalities, largely away from the ever demanding trial-and-error approach. Ministry of Economy, Trade and Industry (METI) and New Energy and Industrial Technology Development Organization (NEDO), Japan, launched in the year 2001 the Synthetic Nanofunction Materials (SYNAF) project under the initiative of METI?s Nanotechnology Program. The objective of this 5-year SYNAF project is to lay a precursory route to the \"nanomaterial design\" by focusing on the single molecular and spintronic materials and devices. By combining the first principle quantum mechanical calculations of molecular wires and spin-dependent band structures of magnetic semiconductors with the state-of-the-art nanofabrication techniques including the probe oxidation nanolithography, we have been successful to demonstrate the (at least partial) feasibility of the design-driven approach to nanomaterials and devices. The present talk will give a summary of our activities and our future prospect.","PeriodicalId":90041,"journal":{"name":"Proceedings ... International Conference on MEMS, NANO, and Smart Systems. International Conference on MEMS, NANO, and Smart Systems","volume":"45 1","pages":"286"},"PeriodicalIF":0.0,"publicationDate":"2004-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72581855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nano-Engineered Polymeric Micelles for Drug Delivery to Resistant Tumor","authors":"A. Lavasanifar","doi":"10.1109/ICMENS.2004.1508903","DOIUrl":"https://doi.org/10.1109/ICMENS.2004.1508903","url":null,"abstract":"Amphiphilic macromolecules self-assemble to nanoscopic core/shell structures in an aqueous environment, namely polymeric micelles that can encapsulate water insoluble drugs, proteins and DNA, and target therapeutics to their site of action in a passive or active way. Polymeric micelles share many structural and functional features with natural transport system, e.g., virus and lipoproteins. The versatility of the synthetic chemistry in polymeric micelles is a bonus providing opportunities to design appropriate nano-carriers for individual delivery requirements. Development of nano-engineered polymeric micellar formulations that can address the problem of drug resistance in cancer is the focus of our current studies. In this context, the effect of chemical manipulations on the encapsulation, release, bio-distribution and cellular interaction of the polymeric nanocarrier is assessed to select appropriate chemistries for optimized delivery of P-glycoprotein substrates to resistant tumors. Early results will be discussed in this presentation.","PeriodicalId":90041,"journal":{"name":"Proceedings ... International Conference on MEMS, NANO, and Smart Systems. International Conference on MEMS, NANO, and Smart Systems","volume":"18 1","pages":"9-11"},"PeriodicalIF":0.0,"publicationDate":"2004-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76596376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Power-Law Scaling Behavior in Barkhausen Avalanches of 2D Ferromagnetic Films","authors":"Sung-chul Shin","doi":"10.1109/ICMENS.2004.124","DOIUrl":"https://doi.org/10.1109/ICMENS.2004.124","url":null,"abstract":"It is recognized that the magnetization reverses with a sequence of discrete and jerky jumps, known as the Barkhausen effect. Recently, interest in the Barkhausen effect has grown as it is a good example of dynamical critical scaling behavior, evidenced by experimental observation of a power law distribution of the Barkhausen jump size. So far, most experimental studies have been carried out on bulk samples using a classical inductive technique, which is difficult to apply to thin film samples mainly due to the low signal intensity. For this reason, very few experiments have been done on two-dimensional ferromagnetic thin films. In this talk, I will report direct domain observations of Barkhausen avalanches at criticality in Co and MnAs nanothin films investigated by means of a magnetooptical microscope magnetometer, capable of time-resolved domain observation in real time. Through a statistical analysis of the fluctuating size of Barkhausen jump from numerous repetitive experiments for each sample, the distribution of Barkhausen jump size is found to exhibit a power-law scaling behavior with the critical exponent τ ∼ 1.33 for all samples having different thickness from 5 to 50 nm. The most striking feature is the fact that the τ values are in the same universality class for all samples within the measurement error despite of the difference in the film thickness. This result implies an invariance of the critical exponent τ irrespective of the number of defects in the thin films. Our experimental results directly verify the CZDS model, where the model describes 180°-type flexible domain wall deformed by localized defects with consideration of long-range dipolar interaction.","PeriodicalId":90041,"journal":{"name":"Proceedings ... International Conference on MEMS, NANO, and Smart Systems. International Conference on MEMS, NANO, and Smart Systems","volume":"65 1","pages":"100-103"},"PeriodicalIF":0.0,"publicationDate":"2004-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86276968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Highly Efficient Spin Filtering of Ballistic Electrons in Hybrid Spin Valve/Semiconductor Structures","authors":"S. J. Steinmuller, T. Trypiniotis, A. Hirohata, W. Cho, W. Lew, C. Vaz, J. Bland","doi":"10.1109/ICMENS.2004.77","DOIUrl":"https://doi.org/10.1109/ICMENS.2004.77","url":null,"abstract":"Efficient spin detection of photoexcited electrons at room temperature in single ferromagnetic (FM) layer/semiconductor (SC) Schottky barrier structures has recently been demonstrated in our group [1,2]. We find that the photocurrent is dependent on the relative alignment of the light helicity with the FM layer magnetisation and attribute this effect to the spin filtering of electrons at the SC/FM interface. In this lecture I first review our recent studies of photoexcited spin dependent transport and then discuss in detail the results of a recent investigation of a hybrid Au/Co/Cu/NiFe/n-GaAs spin valve Schottky barrier structures, where the two FM layers can be switched independently. Circularly polarised light of various wavelengths, modulated with a photoelastic modulator, was used to excite spin polarised electrons in the GaAs at room temperature, and the helicity dependent photocurrent across the spin valve/SC structure was measured using a lock-in amplifier. A 2400% increase in helicity dependent photocurrent was observed when the spin valve was switched from parallel to antiparallel alignment, clearly ruling out a simple superposition of spin filtering at the SC/FM interface and conventional GMR. Furthermore the spin valve/SC structure enabled us to separate the photocurrent across the SC/FM interface from the net measured photocurrent, allowing for the observed spin filtering effect to be quantified. In the antiparallel configuration the current spin polarisation P was found to be 5.9% for h=1.96eV. This shows that high energy electrons are spin filtered with a high degree of efficiency, taking into account the spin polarisation of the electrons photoexcited in the GaAs (10% [3,4]). Moreover the finding that only a small fraction of the photoexcited electrons (about 2.6%) propagates into the spin valve at zero bias proves that the spin filtering observed in previous studies [1,2] is artificially reduced due to electrons passing into the SC. The relative change in helicity dependent photocurrent between parallel and antiparallel spin valve alignment decreases rapidly with decreasing photon energy, suggesting that electrons passing over the Schottky barrier are involved in the spin filtering process. Our combined data provides clear evidence for highly efficient spin filtering of ballistic electrons propagating through the potential energy ��landscape�� of the spin valve structure. The finding that that a spin valve has the capability of detecting a small spin imbalance of the current flowing from the SC into the FM makes it a promising candidate for future spintronic devices.","PeriodicalId":90041,"journal":{"name":"Proceedings ... International Conference on MEMS, NANO, and Smart Systems. International Conference on MEMS, NANO, and Smart Systems","volume":"58 1","pages":"98"},"PeriodicalIF":0.0,"publicationDate":"2004-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83558251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"\"Super Catalytic Antibodies\" Cleaving Targeted Molecules of Viruses and Bacterium","authors":"E. Hifumi, Naoki Johira, T. Uda","doi":"10.1109/ICMENS.2004.1","DOIUrl":"https://doi.org/10.1109/ICMENS.2004.1","url":null,"abstract":"It has been a long time-dream for many scientists to obtain a functional protein which can specifically recognize and futhermore enzymatically decompose the targeted antigens such as viral coat proteins or tumor assosiated proteins. At last, we have succeeded to produce such a novel functional protein refered as \"Super catalytic antibody\". 1. \"Super catalytic antibody\" destroying envelope gp41 molecule of HIV-1 The monoclonal antibody (41S-2 mAb) was raised against the sequence, which is highly conserved in env protein of many HIV-1 strains. The light chain (41S-2-L) degraded the gp41 derived-peptide (TPRGPDRPEGIEEEGGERDRD) into amino acids with high catalytic activity (kcat/Km=2.8 x 105M-1min-1).","PeriodicalId":90041,"journal":{"name":"Proceedings ... International Conference on MEMS, NANO, and Smart Systems. International Conference on MEMS, NANO, and Smart Systems","volume":"75 1","pages":"616"},"PeriodicalIF":0.0,"publicationDate":"2004-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86284789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nanocrystalline Silver and Its Impact on Wound Healing","authors":"R. Burrell","doi":"10.1109/ICMENS.2004.106","DOIUrl":"https://doi.org/10.1109/ICMENS.2004.106","url":null,"abstract":"Silver was one of the first metals discovered and used by man. It was also one of the first medications used to treat or prevent a specific condition. Crede used a 1% silver nitrate solution to prevent and treat opthalmia neonatorum in 1884, just seven years after Pasteur had published his Germ Theory of Disease. In the early 20th century, hammered silver foils and colloidal silver were used to treat indolent wounds. Caregivers reported seeing a decrease in rubor in wounds treated with silver, but with the discovery of antibiotics, research that might have shown why this occurred was never undertaken. In the 1960s, silver was reintroduced to wound care in order to control infections in burn units, first as silver nitrate and then as silver sulfadiazine.","PeriodicalId":90041,"journal":{"name":"Proceedings ... International Conference on MEMS, NANO, and Smart Systems. International Conference on MEMS, NANO, and Smart Systems","volume":"67 1","pages":"497"},"PeriodicalIF":0.0,"publicationDate":"2004-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79633517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Solid Phase Matrices: Cell-Free Micro-Platform for T Cell Recruitment and Stimulation","authors":"A. Kokaji, K. Kane","doi":"10.1109/ICMENS.2004.131","DOIUrl":"https://doi.org/10.1109/ICMENS.2004.131","url":null,"abstract":"Optimal stimulation of antigen specific T cells requires that peptide antigens bound by class I and class II major histocompatibility complex molecules (MHC) are displayed, in conjunction with a variety of costimulatory ligands, on a large surface approximating that of a cell. We have incorporated these principles in the design of cell-free artificial antigen presenting cell surfaces (solid phase matrices, SPMs) constructed on 5 micron latex beads for use in ex vivo T cell stimulation for adoptive immunotherapy and as platforms for T cell vaccines. We demonstrate that naturally expressed or recombinant peptide-MHC complexes and costimulator molecules can be immobilized and displayed simultaneously on the surface of SPMs. Eight or more distinct costimulatory molecules or ligands can be presented on SPMs at physiological densities and the relative density of each ligand can be varied in a precise and independent manner. This allows for control of the contribution of individual ligands relative to others, with the possibility of altering the type of resulting T cell response. The ligands that can be presented on the SPMs include among others: human or mouse class I and class II MHC peptide complexes (antigen specific T cell receptor ligands), B7-1 and 2 (CD28 ligands), 4-1BBL (TNF family costimulator), ICAM-1 (LFA-1 adhesion ligand), CD1d (NKT cell ligand), MICA and Rae-1 antigens (NKG2D costimulatory ligands). All of the immobilized ligands retain their native conformations, since recognition by conformation dependent antibodies is indicated by FACS analysis of the SPMs. Recently, it has been shown that IL-15 receptor alpha (α) can bind the IL-15 cytokine with high affinity and present IL-15 on antigen presenting cells in trans to T cells for stimulation. We are able to display IL-15Rα bound with IL-15 on the SPMs, in addition to peptide-MHC complexes and costimulator ligands to aid T cell responsiveness. We are presently examining the ligand requirements for optimal stimulation of na��ve and effector/memory T cell subsets. We have found that IL-15Rα bound and presented on the SPM has a rapid and profound effect on the recruitment and binding of T cells to the SPMs. Within 2-4 hours, T cells bind avidly to the SPMs bearing the IL-15Rα-IL-15 complex. The ability of the IL-15R-IL-15 complex to recruit T cells to the SPMs may provide improvement to the utility of SPMs as vaccine vehicles, allowing the attraction of T cells to the SPMs displaying T cell antigens and costimulators, despite the non-motile nature of SPMs.","PeriodicalId":90041,"journal":{"name":"Proceedings ... International Conference on MEMS, NANO, and Smart Systems. International Conference on MEMS, NANO, and Smart Systems","volume":"1903 1","pages":"563"},"PeriodicalIF":0.0,"publicationDate":"2004-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87711017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Liquid Nanostructures: Phase Transitions, Forces and Friction","authors":"C. Hemming, S. Overduin, G. Patey","doi":"10.1109/ICMENS.2004.89","DOIUrl":"https://doi.org/10.1109/ICMENS.2004.89","url":null,"abstract":"Grand canonical Monte Carlo calculations and molecular dynamics simulations are used to investigate binary mixtures confined between chemically patterned surfaces. For certain patterns and surface separations, a surfaceinduced phase consisting of liquid \"bridges\" joining like-patterned regions of the plates is observed. Furthermore, since these bridges involve liquid-liquid interfaces their shape and extent can be dramatically altered by simply adding an appropriate surfactant to the mixture. The nanoscale liquid structures associated with a bridge phase can strongly influence both the perpendicular and frictional forces acting on the plates at separations well beyond those where molecular \"ordering\" is dominant. The origin, nature and interesting physical implications of these forces will be discussed.","PeriodicalId":90041,"journal":{"name":"Proceedings ... International Conference on MEMS, NANO, and Smart Systems. International Conference on MEMS, NANO, and Smart Systems","volume":"17 1","pages":"77"},"PeriodicalIF":0.0,"publicationDate":"2004-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77116695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}