ISRN stroke Pub Date : 2014-01-01 DOI: 10.1155/2014/309106

Jane Nakibuuka, Martha Sajatovic, Elly Katabira, Edward Ddumba, Jayne Byakika-Tusiime, Anthony J Furlan

{"title":"Knowledge and Perception of Stroke: A Population-Based Survey in Uganda.","authors":"Jane Nakibuuka, Martha Sajatovic, Elly Katabira, Edward Ddumba, Jayne Byakika-Tusiime, Anthony J Furlan","doi":"10.1155/2014/309106","DOIUrl":"https://doi.org/10.1155/2014/309106","url":null,"abstract":"Purpose: This study, designed to complement a large population survey on prevalence of stroke risk factors, assessed knowledge and perception of stroke and associated factors.Methods: A population survey was conducted in urban Nansana and rural Busukuma, Wakiso district, central Uganda. Adult participants selected by multistage stratified sampling were interviewed about selected aspects of stroke knowledge and perception in a pretested structured questionnaire.Results: There were 1616 participants (71.8% urban; 68.4% female; mean age: 39.6 years ± 15.3). Nearly 3/4 did not know any stroke risk factors and warning signs or recognize the brain as the organ affected. Going to hospital (85.2%) was their most preferred response to a stroke event. Visiting herbalists/traditional healers was preferred by less than 1%. At multivariable logistic regression, good knowledge of stroke warning signs and risk factors was associated with tertiary level of education (OR 4.29, 95% CI 2.13-8.62 and OR 5.96, 95% CI 2.94-12.06), resp.) and self-reported diabetes (OR 1.97, 95% CI 1.18-3.32 and OR 1.84, 95% CI 1.04-3.25), resp.).Conclusion: Knowledge about stroke in Uganda is poor although the planned response to a stroke event was adequate. Educational strategies to increase stroke knowledge are urgently needed as a prelude to developing preventive programmes.","PeriodicalId":89959,"journal":{"name":"ISRN stroke","volume":"2014 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/309106","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32652013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 47

24-Hour ICH Score Is a Better Predictor of Outcome than Admission ICH Score 24小时ICH评分比入院ICH评分更能预测预后

ISRN stroke Pub Date : 2013-10-22 DOI: 10.1155/2013/605286

A. Aysenne, K. Albright, Tiffany L Mathias, Tiffany Chang, A. Boehme, T. Beasley, S. Martin-Schild

{"title":"24-Hour ICH Score Is a Better Predictor of Outcome than Admission ICH Score","authors":"A. Aysenne, K. Albright, Tiffany L Mathias, Tiffany Chang, A. Boehme, T. Beasley, S. Martin-Schild","doi":"10.1155/2013/605286","DOIUrl":"https://doi.org/10.1155/2013/605286","url":null,"abstract":"Background The ICH score is a validated tool for predicting 30-day morbidity and mortality in patients with intracerebral hemorrhage. Aims and/or Hypothesis The aim of this study is to determine if the ICH score calculated 24 hours after admission is a better predictor of mortality than the ICH score calculated on admission. Methods Patients presenting to our center with ICH from 7/08-12/10 were retrospectively identified from our prospective stroke registry. ICH scores were calculated based on initial Glasgow coma scale (GCS) and emergent head computed tomography (CT) on initial presentation and were recalculated after 24 hours. Results A total of 91 patients out of 121 had complete data for admission and 24-hour ICH score. The ICH score changed in 38% from baseline to 24 hours. After adjusting for age, NIHSS on admission, and glucose, ICH score at 24 hours was a significant, independent predictor of mortality (OR = 2.71, 95% CI 1–19–6.20, and P = 0.018), but ICH score on admission was not (OR = 2.14, 95% CI 0.88-5.24, and P = 0.095). Conclusion Early determination of the ICH score may incorrectly estimate the severity and expected outcome after ICH. Calculations of the ICH score 24 hours after admission will better predict early outcomes.","PeriodicalId":89959,"journal":{"name":"ISRN stroke","volume":"2013 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2013-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/605286","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64174040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12

Hospital-Acquired Infection Underlies Poor Functional Outcome in Patients with Prolonged Length of Stay. 医院获得性感染是住院时间较长的患者功能预后不良的原因。

ISRN stroke Pub Date : 2013-08-14 DOI: 10.1155/2013/312348

Alexander J George, Amelia K Boehme, James E Siegler, Dominique Monlezun, Bethena D Fowler, Amir Shaban, Karen C Albright, T Mark Beasley, Sheryl Martin-Schild

{"title":"Hospital-Acquired Infection Underlies Poor Functional Outcome in Patients with Prolonged Length of Stay.","authors":"Alexander J George, Amelia K Boehme, James E Siegler, Dominique Monlezun, Bethena D Fowler, Amir Shaban, Karen C Albright, T Mark Beasley, Sheryl Martin-Schild","doi":"10.1155/2013/312348","DOIUrl":"https://doi.org/10.1155/2013/312348","url":null,"abstract":"Introduction: Prolonged length of stay (pLOS) following ischemic stroke inflates cost, increases risk for hospital-acquired complications, and has been associated with worse prognosis.Methods: Acute ischemic stroke patients admitted between July 2008 and December 2010 were retrospectively analyzed for pLOS, defined as a patient stable for discharge hospitalized for an additional ≥24 hours.Results: Of 274 patients included, 106 (38.7%) had pLOS (median age 65 years, 60.6% female, 69.0% black). Patients with pLOS had higher admission NIHSS than patients without pLOS (9 versus 5, P = 0.0010). A larger proportion of patients with pLOS developed an infection (P < 0.0001), and after adjusting for covariates, these patients had greater odds of poor short-term functional outcome (OR = 2.25, 95% CI 1.17-4.32, P = 0.0148). Adjusting for infection, the odds of patients with pLOS having poor short-term functional outcome were no longer significant (OR = 1.68, 95% CI 0.83-3.35, P = 0.1443).Conclusions: The contraction of a hospital-acquired infection was a significant predictor of pLOS and a contributor of poor short-term outcome following an ischemic stroke. Whether the cause or the consequence of pLOS, hospital-acquired infections are largely preventable and a target for reducing length of stay.","PeriodicalId":89959,"journal":{"name":"ISRN stroke","volume":"2013 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2013-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/312348","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31988817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 22

The Impact of Left Ventricular Hypertrophy and Diastolic Dysfunction on Outcome in Intracerebral Hemorrhage Patients. 脑出血患者左室肥厚和舒张功能不全对预后的影响。

ISRN stroke Pub Date : 2013-01-01 DOI: 10.1155/2013/898163

Karen C Albright, Joshua M Burak, Tiffany R Chang, Aimee Aysenne, James E Siegler, Laurie Schluter, Sharyl R Martini, Amelia K Boehme, Sheryl Martin-Schild

{"title":"The Impact of Left Ventricular Hypertrophy and Diastolic Dysfunction on Outcome in Intracerebral Hemorrhage Patients.","authors":"Karen C Albright, Joshua M Burak, Tiffany R Chang, Aimee Aysenne, James E Siegler, Laurie Schluter, Sharyl R Martini, Amelia K Boehme, Sheryl Martin-Schild","doi":"10.1155/2013/898163","DOIUrl":"https://doi.org/10.1155/2013/898163","url":null,"abstract":"Background: The objective of this study was to determine the prevalence of LVH and DD in patients presenting with supratentorial deep ICH and to determine if the presence of LVH or DD was an independent predictor of initial ICH volume, hematoma expansion, or poor outcome.Methods: A cross-sectional study was performed on ICH patients who presented from 7/2008 to 12/2010. Cases were excluded if ICH was traumatic, lobar, infratentorial, secondary to elevated international normalized ratio, suspicious for underlying structural malformation, or where surgical evacuation was performed. Logistic and linear regressions were used to assess the ability of LVH to predict ICH imaging characteristics and patient outcomes.Results: After adjusting for use of hemostatic agents, LVH was not a significant independent predictor of initial ICH volume (P = 0.344) or 33% volume expansion (P = 0.378). After adjusting for age, infectious complications, and use of hemostatic agents, LVH was not a significant independent predictor of poor functional outcome (P = 0.778). Similar results were seen for DD.Conclusion: In our sample, patients with deep ICH and LVH were more likely to develop IVH, but LVH was not a significant independent predictor of initial ICH volume, hematoma expansion, or poor short-term outcome.","PeriodicalId":89959,"journal":{"name":"ISRN stroke","volume":"2013 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886815/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32022319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Hemorrhagic Transformation (HT) and Symptomatic Intracerebral Hemorrhage (sICH) Risk Prediction Models for Postthrombolytic Hemorrhage in the Stroke Belt. 脑卒中带溶栓后出血的出血转化(HT)和症状性脑出血(siich)风险预测模型

ISRN stroke Pub Date : 2013-01-01 DOI: 10.1155/2013/681673

James E Siegler, Muhammad Alvi, Amelia K Boehme, Michael J Lyerly, Karen C Albright, Reza Bavarsad Shahripour, Pawan V Rawal, Niren Kapoor, April Sisson, J Thomas Houston, Anne W Alexandrov, Sheryl Martin-Schild, Andrei V Alexandrov

{"title":"Hemorrhagic Transformation (HT) and Symptomatic Intracerebral Hemorrhage (sICH) Risk Prediction Models for Postthrombolytic Hemorrhage in the Stroke Belt.","authors":"James E Siegler, Muhammad Alvi, Amelia K Boehme, Michael J Lyerly, Karen C Albright, Reza Bavarsad Shahripour, Pawan V Rawal, Niren Kapoor, April Sisson, J Thomas Houston, Anne W Alexandrov, Sheryl Martin-Schild, Andrei V Alexandrov","doi":"10.1155/2013/681673","DOIUrl":"https://doi.org/10.1155/2013/681673","url":null,"abstract":"Background: Symptomatic intracerebral hemorrhage (sICH) remains the most feared complication of intravenous tissue plasminogen activator (IV tPA) treatment. We aimed to investigate how previously validated scoring methodologies would perform in treated patients in two US Stroke Belt states.Methods and results: We retrospectively reviewed consecutive patients from two centers in two Stroke Belt states who received IV tPA (2008-2011). We assessed the ability of three models to predict sICH. sICH was defined as a type 2 parenchymal hemorrhage with deterioration in National Institutes of Health Stroke Scale (NIHSS) score of ≥4 points or death. Among 457 IV tPA-treated patients, 19 (4.2%) had sICH (mean age 68, 26.3% Black, 63.2% female). The Cucchiara model was most predictive of sICH in the entire cohort (AUC: 0.6528) and most predictive of sICH among Blacks (OR = 6.03, 95% CI 1.07-34.1, P = 0.0422) when patients were dichotomized by score.Conclusions: In our small sample from the racially heterogeneous US Stroke Belt, the Cucchiara model outperformed the other models at predicting sICH. While predictive models should not be used to justify nontreatment with thrombolytics, those interested in understanding contributors to sICH may choose to use the Cucchiara model until a Stroke Belt model is developed for this region.","PeriodicalId":89959,"journal":{"name":"ISRN stroke","volume":"2013 ","pages":"681673"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/681673","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32096287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

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