{"title":"Intensive insulin therapy to maintain normoglycemia after cardiac surgery.","authors":"G Van den Berghe","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Drugs used in the perioperative period could have an effect on survival as recently pointed out by an international consensus conference on the reduction in mortality in cardiac anesthesia and intensive care. Insulin infusion to achieve a strict glycemic control is the best example of how an ancillary (i.e. non-surgical) drug/technique/strategy might influence survival rates in patients undergoing cardiac surgery. The author of this \"expert opinion\" presents her insights into the use of insulin in this setting and suggest that based on available evidence based medicine, insulin infusion, titrated to \"normoglycemia\" is a complex intervention, that not only requires the simple administration of a \"drug\", the hormone insulin, but also needs tools and skills to accurately measure and control blood glucose to achieve normoglycemia while avoiding hypoglycemia and large glucose fluctuations.</p>","PeriodicalId":89769,"journal":{"name":"HSR proceedings in intensive care & cardiovascular anesthesia","volume":"3 2","pages":"97-101"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a5/7f/hsrp-03-097.PMC3484624.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31355392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E M Delmo Walter, O Miera, B Nasseri, M Huebler, V Alexi-Meskishvili, F Berger, R Hetzer
{"title":"Onset of pulmonary stenosis after arterial switch operation for transposition of great arteries with intact ventricular septum.","authors":"E M Delmo Walter, O Miera, B Nasseri, M Huebler, V Alexi-Meskishvili, F Berger, R Hetzer","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Pulmonary stenosis remains the most frequent complication and cause of reintervention after the arterial switch operation for transposition of the great arteries We investigated the onset, incidence, and outcome of pulmonary stenosis after arterial switch operation in neonates with transposition of the great arteries and intact ventricular septum.</p><p><strong>Methods: </strong>Arterial switch operation using Lecompte maneuver was performed in 222 neonates with transposition of great arteries and intact ventricular septum. Complete medical records with serial echocardiograms were available for 174 (73%) patients and were reviewed for incidence of postoperative pulmonary stenosis defined as a thickened and doming pulmonary valve and/or a pressure gradient of >25 mmHg.</p><p><strong>Results: </strong>During a mean follow-up of 14.4 ± 0.54 years, 31 children developed pulmonary stenosis. Onset of significant stenosis occurred as early as 30 days and as late as 10 years after arterial switch operation. Uncomplicated interventional balloon/stent angioplasty was performed in 11 patients with supravalvular stenosis (mean pressure gradients of 65 mmHg). Severe restenosis occurred in these patients post-angioplasty (range 2-7 years). In other 10 patientseither patch enlargement of the area involved or angioplasty were performed. Freedom from intervention was 68.6±8.7% at 1 year and 42.8.1±9.5% at 15 years and onwards.</p><p><strong>Conclusion: </strong>Over time, pulmonary stenosis developed after arterial switch operation. Balloon angioplasty for supravalvular pulmonary stenosis could be the initial treatment of choice owing to the high success rate. Surgical intervention is offered to those with pulmonary valve stenosis having pressure gradients of >50 mmHg, and for re-stenosis after intervention/stent implantation.</p>","PeriodicalId":89769,"journal":{"name":"HSR proceedings in intensive care & cardiovascular anesthesia","volume":"3 3","pages":"177-87"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c3/8e/hsrp-03-177.PMC3484630.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31355880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Intracranial placement of a nasogastric tube in a non-trauma patient","authors":"F. Araimo, R. Caramia, E. Meschesi","doi":"10.21767/2471-8505.100108","DOIUrl":"https://doi.org/10.21767/2471-8505.100108","url":null,"abstract":"Source of Support Nil. Conflict of interest None declared. Cite as: Araimo F, Caramia R, Meschesi E. Intracranial placement of a nasogastric tube in a non-trauma patient. HSR Proceedings in Intensive Care and Cardiovascular Anesthesia 2011; 3(1): 71","PeriodicalId":89769,"journal":{"name":"HSR proceedings in intensive care & cardiovascular anesthesia","volume":"3 1","pages":"71 - 71"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.21767/2471-8505.100108","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68138617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Use of recombinant activated factor VII for bleeding following resection of mediastinal angiosarcoma.","authors":"D Arora, Y Mehta, N Trehan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Sarcomatous lesions of the mediastinum usually present as aggressive and multicentre masses often attached to adjoining structures including heart and lungs. A forty one year male diagnosed with sarcomatous lesion in mediastinum presented for biopsy through midsternotomy later confirmed as angiosarcoma on histopathology. Patient bled excessively after surgery and required reopening of the chest. However, bleeding could not be controlled with reopening, blood products and packing of the mediastinal cavity. Bleeding could only be controlled by using recombinant activated factor VII as rescue therapy without any adverse effects.</p>","PeriodicalId":89769,"journal":{"name":"HSR proceedings in intensive care & cardiovascular anesthesia","volume":"3 3","pages":"197-201"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b8/3e/hsrp-03-197.PMC3484629.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31264038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A Grimaldi, E Ammirati, D Piraino, A C Vermi, I Arendar, F Sacco, G La Canna, O Alfieri
{"title":"Sudden hypotensive syndrome mimicking acute pulmonary embolism after major abdominal surgery.","authors":"A Grimaldi, E Ammirati, D Piraino, A C Vermi, I Arendar, F Sacco, G La Canna, O Alfieri","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":89769,"journal":{"name":"HSR proceedings in intensive care & cardiovascular anesthesia","volume":"3 1","pages":"73-4"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9f/d4/hsrp-03-073.PMC3484605.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31265234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"I really think you should publish this paper: the cover letter to the editor.","authors":"M John","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":89769,"journal":{"name":"HSR proceedings in intensive care & cardiovascular anesthesia","volume":"3 2","pages":"137-9"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/43/f4/hsrp-03-137.PMC3484622.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31264563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Severe mitral regurgitation treated by ventricular septal myectomy.","authors":"F S Silva, A L Nobre","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":89769,"journal":{"name":"HSR proceedings in intensive care & cardiovascular anesthesia","volume":"3 2","pages":"131-3"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b3/20/hsrp-03-131.PMC3484620.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31264561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Meta-analyses of diagnostic tests in infectious diseases: how helpful are they in the intensive care setting?","authors":"M Cruciani","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In acute-care settings timely and accurate diagnostic tools are critical for patient treatment decisions and outcomes. This review provides an up-to-date look at the meta-analyses of diagnostic test for infections in the ICU setting. There have been 3 meta-analyses investigating the value of procalcitonin as diagnostic marker of sepsis: overall, the performance of procalcitonin test was found moderate-good. Two meta-analyses evaluated methods for diagnosing intravascular device-related bloodstream infections. In general, quantitative catheter segment culture and paired quantitative blood culture showed reliable diagnostic yield, though significant heterogeneity was observed among studies. Criteria of diagnosing VAP in the intensive care unit has been evaluated in 3 systematic reviews. Overall, the cumulative results cast doubts about the usefulness of bacteriological data and quantitative cultures in the diagnosis of VAP; moreover, 2 of these meta-analyses concluded that invasive strategies for VAP diagnosis do not affect mortality.</p>","PeriodicalId":89769,"journal":{"name":"HSR proceedings in intensive care & cardiovascular anesthesia","volume":"3 2","pages":"103-8"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/54/4f/hsrp-03-103.PMC3484627.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31263864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Analgesia for thoracic surgery: the role of paravertebral block.","authors":"E Piraccini, E A Pretto, R M Corso, G Gambale","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>An appropriate post operative analgesia after thoracotomies is mandatory to improve the patient's outcome, reduce complications rate, morbidity, hospital cost and length of stay. In this paper we review the evidences regarding the use of paravertebral block for thoracic surgery. In particular we examine the effect of paravertebral block compared to the other technique in four major issues: analgesia, complications rate, postoperative pulmonary function and transition from acute to chronic pain. We conclude that paravertebral block is superior to intravenous analgesia in providing pain control and preserving postoperative pulmonary function while it is equal to thoracic epidural analgesia regarding this two issues. Paravertebral block has a better safety profile when compared to intravenous and thoracic epidural analgesia. Its effect on chronic pain incidence still needs further studies.</p>","PeriodicalId":89769,"journal":{"name":"HSR proceedings in intensive care & cardiovascular anesthesia","volume":"3 3","pages":"157-60"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b8/da/hsrp-03-157.PMC3484628.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31264093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G Biondi-Zoccai, M Lotrionte, G Landoni, M G Modena
{"title":"The rough guide to systematic reviews and meta-analyses.","authors":"G Biondi-Zoccai, M Lotrionte, G Landoni, M G Modena","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The hierarchy of evidence based medicine postulates that systematic reviews of homogenous randomized trials represent one of the uppermost levels of clinical evidence. Indeed, the current overwhelming role of systematic reviews, meta-analyses and meta-regression analyses in evidence based heath care calls for a thorough knowledge of the pros and cons of these study designs, even for the busy clinician. Despite this sore need, few succinct but thorough resources are available to guide users or would-be authors of systematic reviews. This article provides a rough guide to reading and, summarily, designing and conducting systematic reviews and meta-analyses.</p>","PeriodicalId":89769,"journal":{"name":"HSR proceedings in intensive care & cardiovascular anesthesia","volume":"3 3","pages":"161-73"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/30/5a/hsrp-03-161.PMC3484632.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31355890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}