{"title":"DONALD M. BRUNETTE, PHD, Professor Emeritus, Department of Oral Biological & Medical Sciences, Faculty of Dentistry, University of British Columbia, Vancouver, Canada","authors":"Donald M. Brunette PHD","doi":"10.1111/etp.12102","DOIUrl":"10.1111/etp.12102","url":null,"abstract":"","PeriodicalId":89760,"journal":{"name":"Endodontic topics","volume":"34 1","pages":"90"},"PeriodicalIF":0.0,"publicationDate":"2016-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/etp.12102","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63239671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Farewell to Endodontic Topics","authors":"Markus Haapasalo","doi":"10.1111/etp.12101","DOIUrl":"10.1111/etp.12101","url":null,"abstract":"<p>Dear Reader:</p><p>You are viewing the last volume of <i>Endodontic Topics</i>! After repeated but unsuccessful efforts by the publisher to list <i>Endodontic Topics</i> in Medline (PubMed), continuing the journal became too challenging. Writing review articles is demanding and takes an enormous amount of time—thus the authors must get their reward. Typically, the reward would be that the article is part of the Medline database, which guarantees citations and thereby academic merit to the authors. Being outside Medline does not give the same added bonus to the number of citations and h-index, both of which are important measures of success in academic activity. Recruiting “volunteer” authors therefore was an ever-increasing challenge. Last year, after 10 years as Editor-in-Chief, I informed the publisher that my term was coming to an end, and the publisher was unable to find a new EIC to continue to carry the journal further.</p><p><i>Endodontic Topics</i> was initiated in 2002 under the leadership of Prof. Martin Trope, together with some of the most prominent names in endodontics. In 2006, the “founders” wanted to step aside and I was invited to continue to lead our journal. I am writing “our journal” because <i>Endodontic Topics</i>, despite not being included in Medline, has been enormously popular among endodontists and graduate endodontic students throughout its public life. The number of downloaded articles has been extremely high, all over the world. The top 25 most downloaded articles since 2010 appear here. There is no doubt in my mind that <i>Endodontic Topics</i> has contributed greatly to the advancement of our profession, both with regard to clinical skills and especially in deepening our understanding of endodontic theory. The journal has been the “best friend” of many program directors in their important role in educating new generations of endodontists.</p><p>I have had the great pleasure of working together with a talented group of associate editors: Leif Bakland, Anil Kishen, Dag Ørstavik, Ove Peters, Ya Shen, and Fabricio Teixeira. Their constant contribution and commitment to the journal have been crucial to the high quality and popularity of <i>Endodontic Topics</i>. Mrs. Ingrid Ellis has been the copy editor of <i>Endodontic Topics</i> throughout my editorship period; her dedication and high standards have been extremely valuable to the journal. While I will greatly miss the journal, I will miss equally as much the communication around publishing <i>Endodontic Topics</i> with my colleagues and my friends.</p><p>Numerous authors in endodontics have contributed to <i>Endodontic Topics</i>. From the beginning, it has been regarded as a special honor to be invited to write for the journal. Author biographies at the end of each volume have emphasized this and also spread knowledge about leaders in the field of endodontics to our colleagues around the world. I cannot thank enough all who have contributed to <i>Endodontic Topic","PeriodicalId":89760,"journal":{"name":"Endodontic topics","volume":"34 1","pages":"7"},"PeriodicalIF":0.0,"publicationDate":"2016-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/etp.12101","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63239606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"MARKUS HAAPASALO, DDS, DR ODONT, FRCDC, Professor and Chair, Division of Endodontics, Department of Oral Biological & Medical Sciences, Faculty of Dentistry, University of British Columbia, Vancouver, Canada","authors":"Markus Haapasalo DDS, DR ODONT, FRCDC","doi":"10.1111/etp.1_12102","DOIUrl":"https://doi.org/10.1111/etp.1_12102","url":null,"abstract":"","PeriodicalId":89760,"journal":{"name":"Endodontic topics","volume":"34 1","pages":"91"},"PeriodicalIF":0.0,"publicationDate":"2016-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/etp.1_12102","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137539843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Epidemiology of post-treatment disease","authors":"Michael Hülsmann","doi":"10.1111/etp.12096","DOIUrl":"10.1111/etp.12096","url":null,"abstract":"<p>Endodontic treatment aims to eliminate or prevent diseases of the pulp and the apical periodontium. Although several strategies have been developed to combat pulpal and periapical inflammation and infection, success rates in endodontics still seem to range considerably below 100%. A critical review of epidemiological studies demonstrates that post-treatment endodontic disease needs to be acknowledged as a common outcome of endodontic treatment. The following review presents the data of available epidemiological studies from different continents and countries. The overall prevalence of post-endodontic apical lesions ranges clearly higher than the failure rates obtained from well-designed clinical studies demonstrating severe deficits in endodontic treatment in daily general dental practice.</p>","PeriodicalId":89760,"journal":{"name":"Endodontic topics","volume":"34 1","pages":"42-63"},"PeriodicalIF":0.0,"publicationDate":"2016-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/etp.12096","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63239801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Non-surgical retreatment of teeth with persisting apical periodontitis following apicoectomy: decision making, treatment strategies and problems, and case reports","authors":"Michael Hülsmann, Gabriel Tulus","doi":"10.1111/etp.12098","DOIUrl":"10.1111/etp.12098","url":null,"abstract":"<p>In the endodontic literature, only a few studies and case reports can be found demonstrating and further discussing non-surgical treatment of failed apicoectomies. As a second apicoectomy has a limited success rate, non-surgical retreatment should be discussed as an additional treatment option before extraction is considered. Depending on the reason for treatment failure or for persistence or development of apical periodontitis, and depending on the presence or absence and the type of retrofilling, treatment strategies need to be adapted to the specific clinical scenario. It is the aim of this review to describe a strategy for non-surgical orthograde retreatment of previously apicected teeth with persisting apical periodontitis, to review the literature that may be helpful to discuss such cases, to develop an individual treatment plan, to discuss several specific aspects of treatment, and to present different clinical cases.</p>","PeriodicalId":89760,"journal":{"name":"Endodontic topics","volume":"34 1","pages":"64-89"},"PeriodicalIF":0.0,"publicationDate":"2016-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/etp.12098","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63239868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Level of evidence in endodontics: what does it mean?","authors":"Markus Haapasalo","doi":"10.1111/etp.12099","DOIUrl":"10.1111/etp.12099","url":null,"abstract":"<p>This review is a short summary of how the level of evidence in endodontics and endodontic research in particular is defined. The goal of this review is to help dentists and endodontists to become familiar with the evidence pyramid and thereby better evaluate the reliability of evidence on daily practices and choices in patient care. All medical treatment, including endodontic treatment, should be based on the best available evidence. In this review, the definition of evidence is presented and the different levels in the evidence pyramid are discussed with a special focus on endodontics. Much of the presently published endodontic research is done <i>in vitro</i>, which is regarded as the lowest level of evidence. However, it is important to understand that a low level of evidence does not mean that the research in itself is of poor quality or somehow unreliable. Instead, it means that one cannot draw conclusions from <i>in vitro</i> studies to clinical events with a high probability of accuracy. The <i>in vitro</i> results may be true, and often are, but more evidence from different types of studies such as case-control and cohort studies and even randomized controlled trials is needed to increase the probability that the results obtained in research do in fact correctly reflect the real events, e.g. level of probability of healing after a specific type of treatment for a specific disease. This review also discusses why the highest level of evidence may be difficult to obtain for a variety of practical and ethical reasons, and why not all endodontic treatment needs to be based on information from randomized controlled trials and systematic reviews.</p>","PeriodicalId":89760,"journal":{"name":"Endodontic topics","volume":"34 1","pages":"30-41"},"PeriodicalIF":0.0,"publicationDate":"2016-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/etp.12099","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63239913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Statistics and level of evidence in endodontic research Epidemiology and treatment of post-treatment endodontic disease","authors":"Markus Haapasalo","doi":"10.1111/etp.12100","DOIUrl":"10.1111/etp.12100","url":null,"abstract":"","PeriodicalId":89760,"journal":{"name":"Endodontic topics","volume":"34 1","pages":"5-6"},"PeriodicalIF":0.0,"publicationDate":"2016-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/etp.12100","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63239566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"MICHAEL HÜLSMANN, DDS, PHD, Professor, Department of Preventive Dentistry, Periodontology & Cariology, University of Göttingen, Göttingen, Germany","authors":"Michael Hülsmann DDS, PHD","doi":"10.1111/etp.2_12102","DOIUrl":"https://doi.org/10.1111/etp.2_12102","url":null,"abstract":"","PeriodicalId":89760,"journal":{"name":"Endodontic topics","volume":"34 1","pages":"92"},"PeriodicalIF":0.0,"publicationDate":"2016-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/etp.2_12102","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137703756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Statistical and other methodological issues in the production of reliable experimental endodontic research and why they matter","authors":"Donald M. Brunette","doi":"10.1111/etp.12097","DOIUrl":"10.1111/etp.12097","url":null,"abstract":"<p>It has long been assumed that science is self-correcting and that lack of reproducibility or even fraud will be uncovered in subsequent attempts to replicate observations or experiments. Recent studies have cast doubt on that assumption, which is a central tenet of scientific method, even for research that is published in high-impact journals and uses state-of-the-art methodology. Ironically, endodontic research, like most biomedical research, is moving toward highly sophisticated procedures such as gene arrays and proteomics, which are often plagued by false positives and false negatives. This “reproducibility crisis” is thought to arise from many sources including poorly described methodology, inappropriate statistical analysis, the positive bias for article acceptance by journals, the lack of incentives to repeat experiments, and the hypercompetitive research environment that pressures investigators to publish quickly in impact journals. This article outlines the scope of the reproducibility crisis and some of the steps that may be used to ameliorate it. Attention is focused on common statistical errors and pitfalls, the use of confidence intervals in place of the standard Null Hypothesis Statistical Testing (NHST), and the promise of Bayesian statistics in endodontic research.</p>","PeriodicalId":89760,"journal":{"name":"Endodontic topics","volume":"34 1","pages":"8-29"},"PeriodicalIF":0.0,"publicationDate":"2016-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/etp.12097","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63239856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}