发布求助
文献互助 智能选刊 最新文献

Asia-Pacific biotech news最新文献

筛选
英文 中文
Urine Metabolomics Reveals Overlapping Metabolic Associations Between Preeclampsia and Gestational Diabetes. 尿液代谢组学揭示先兆子痫与妊娠糖尿病之间重叠的代谢关系
Asia-Pacific biotech news Pub Date : 2024-07-01 Epub Date: 2022-12-06 DOI: 10.1007/s12291-022-01103-2
Nupur Rani Agarwal, Garima Kachhawa, Bolaji Fatai Oyeyemi, Neel Sarovar Bhavesh
{"title":"Urine Metabolomics Reveals Overlapping Metabolic Associations Between Preeclampsia and Gestational Diabetes.","authors":"Nupur Rani Agarwal, Garima Kachhawa, Bolaji Fatai Oyeyemi, Neel Sarovar Bhavesh","doi":"10.1007/s12291-022-01103-2","DOIUrl":"10.1007/s12291-022-01103-2","url":null,"abstract":"<p><p>Pregnancy is associated with numerous metabolic adaptations to meet the demands of the growing foetus. These adaptations could be perturbed during pregnancy due to preeclampsia (PE) and gestational diabetes (GDM). As these two obstetric aliments show some overlapping pathophysiology and similar biochemical dysregulation, the present study was undertaken to compare urine metabolome of PE and GDM with normal pregnancy (NT) in all trimesters of gestation using nuclear magnetic resonance spectroscopy-based metabolomics analysis to ascertain and compare metabolome in the study groups. We observed overlapping metabolic perturbations in PE and GDM. Though a study with a small sample size, this is the first report which confirms significantly differential metabolites in urine of both PE and GDM. Dimethylglycine and oxoglutaric acid were decreased while benzoic acid was increased in both the cases in all trimesters. Alanine, aspartate and glutamate metabolism, aminoacyl-tRNA biosynthesis, citrate and butanoate metabolism were the most perturbed pathways in both PE and GDM across pregnancy. These pathways have an association with energy metabolism, glucose homeostasis, insulin sensitivity and oxidative stress which play an important role in the development and progression of PE and GDM. In conclusion, our study showed that urine metabolome could reflect metabolic associations between PE and GDM and also in the identification of biomolecules that could be used as potential biomarker(s) for early detection of the metabolic diseases in pregnancy.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s12291-022-01103-2.</p>","PeriodicalId":89742,"journal":{"name":"Asia-Pacific biotech news","volume":"10 1","pages":"356-364"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11239642/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86395513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pixel Perfect – Imaging Technologies in Biomedical Research (Vol. 27, Nos. 03n04, Full Issue) 像素完美-生物医学研究中的成像技术(第27卷，第03n04号，全期)
Asia-Pacific biotech news Pub Date : 2023-09-26 DOI: 10.1142/s0219030323000034
{"title":"Pixel Perfect – Imaging Technologies in Biomedical Research (Vol. 27, Nos. 03n04, Full Issue)","authors":"","doi":"10.1142/s0219030323000034","DOIUrl":"https://doi.org/10.1142/s0219030323000034","url":null,"abstract":"In this issue, we have two highlights that will look at how far imaging technologies have come since the X-ray. First, Keefe Chee from BD Life Sciences, Singapore, discusses how real-time imaging spectral flow cytometry (RTI-SFC) allows scientists to identify previously unclassifiable cells in real time, bridging a long-standing gap in biomedical research. And then we have Torrey Smith, CEO of Endiatx, to share with us about PillBot™, the world's first motorised pill camera that will allow a doctor to view the entire stomach and assess for any lesions, making stomach cancer diagnosis more accessible and palatable. Finally, some research highlights we have this issue include a novel diagnostic tool that will improve the clinical diagnosis of neurodegenerative disorders, a textile that can convert body movement into electricity, and a uterine tissue-specific hydrogel that could aid in infertility.","PeriodicalId":89742,"journal":{"name":"Asia-Pacific biotech news","volume":"2012 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134957906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transforming Healthcare With Technology (Vol. 27, No. 02, Full Issue) 科技变革医疗(27卷02期，全期)
Asia-Pacific biotech news Pub Date : 2023-06-01 DOI: 10.1142/s0219030323000022
{"title":"Transforming Healthcare With Technology (Vol. 27, No. 02, Full Issue)","authors":"","doi":"10.1142/s0219030323000022","DOIUrl":"https://doi.org/10.1142/s0219030323000022","url":null,"abstract":"In this issue, APBN looks at the technology that have improved our understanding of the human body and paved the way for future treatments and therapies. First off, we learn about pneumococcal vaccination and how it offers protection against bacterial pneumonia with Dr Chew Huck Chin, respiratory physician and intensivist at Mount Elizabeth Novena Hospital. Then, we hear from Yutaka Shimokawa, Founder and CEO of KINS, about how gut microbes can improve women's hormonal health. In Spotlights, we bring you the highlights from the recent Asia Summit on Global Health as well as an interview with Dr Tan Hong Chang, Senior Consultant at the Singapore General Hospital, and Associate Professor Liu Yu-Chi, Clinician Scientist at the Singapore National Eye Centre, on how a cholesterol drug was repurposed as a new treatment for diabetic corneal neuropathy. In Columns, Dr Jane Leong, Vice President, Medical Affairs Asia Pacific for Moderna, shares how recent developments in mRNA technology could change the way we approach cancer other diseases.","PeriodicalId":89742,"journal":{"name":"Asia-Pacific biotech news","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45181964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Future of Cancer Medicine is Precision (Vol. 27, No. 01, Full Issue) 癌症医学的未来是精确的（第27卷第01期，全文）
Asia-Pacific biotech news Pub Date : 2023-03-01 DOI: 10.1142/s0219030323000010
{"title":"The Future of Cancer Medicine is Precision (Vol. 27, No. 01, Full Issue)","authors":"","doi":"10.1142/s0219030323000010","DOIUrl":"https://doi.org/10.1142/s0219030323000010","url":null,"abstract":"In this issue, APBN looks into new developments happening within the field of oncology and considers how biotechnology is paving the way for more effective cancer treatments. Firstly, we have Dr Kim Strydom and Dr Edwin Gumafelix of IQVIA to share about CAR-T cell therapy and how we can optimise its clinical trial process to benefit a larger group of patients. Then, Vishal Doshi of AUM Biosciences looks into the potential of biotechnology in transforming cancer therapeutics and how precision medicine can bridge the gaps in cancer care. In Spotlights, we spoke to Dr Lim Hwee Yong, Specialist Medical Oncologist at the Novena Cancer Centre about lung cancer and how the drug Rybrevant presents a hope for patients with a rare type of lung cancer. Finally, in Columns, Dr Varun Sethi of DKSH Business Unit Healthcare describes some of the key trends in Asia-Pacific's healthcare ecosystem and what we can expect to see this year.","PeriodicalId":89742,"journal":{"name":"Asia-Pacific biotech news","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42435864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Worlds Within Worlds – Viruses, Humanity, and the Environment (Vol. 26, No. 11n12, Full Issue) 世界中的世界-病毒、人类和环境(第26卷，第11n12号，完整版)
Asia-Pacific biotech news Pub Date : 2022-11-01 DOI: 10.1142/s0219030322000076
{"title":"Worlds Within Worlds – Viruses, Humanity, and the Environment (Vol. 26, No. 11n12, Full Issue)","authors":"","doi":"10.1142/s0219030322000076","DOIUrl":"https://doi.org/10.1142/s0219030322000076","url":null,"abstract":"For the months of November and December 2022, APBN explores the theme of ''Virology'' and considers the role they play in our environment and how we can deal with them in the years to come. Firstly, we dive into the world of marine viruses with Vanessa Lunardi as she shares with us how these microscopic agents direct life in the ocean and how they could potentially contribute to climate change. Next, Dr Sunny Himansu, Associate Director of Infectious Diseases at Moderna, talks about the Nipah virus, its presence in Southeast Asia, and how Moderna is working to develop a Nipah virus mRNA vaccine. Closer to home, Junghun Justin Kim, Country Manager at Takeda Singapore, discusses the issue of dengue – a disease that has seen a three-fold increase in Singapore this year – and how we can best manage it. Other highlights in this issue include a column by Ivor Campbell, CEO of Snedden Campbell, on the various developments in diagnostics and medical technology as a result of the COVID-19 pandemic, and an interview with Erica Wu Yun, Nurse Clinician at Allium Care Suites on how we can best prepare for a transition from life to death.","PeriodicalId":89742,"journal":{"name":"Asia-Pacific biotech news","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45152401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Toxins and Medicines – Two Sides of the Same Coin (Vol. 26, No. 09n10, Full Issue) 毒素与药物-同一事物的正反两面(第二十六卷，第09n10号，全版)
Asia-Pacific biotech news Pub Date : 2022-09-01 DOI: 10.1142/s0219030322000064
{"title":"Toxins and Medicines – Two Sides of the Same Coin (Vol. 26, No. 09n10, Full Issue)","authors":"","doi":"10.1142/s0219030322000064","DOIUrl":"https://doi.org/10.1142/s0219030322000064","url":null,"abstract":"For the months of September and October 2022, APBN looks at toxins from the natural world and consider its benefits to humanity despite the negative connotation. First up, we have a contribution from Vanessa Lunardi on snake venoms in venom therapy. Then Tara Ng dives into plant secondary metabolites, its properties, and potential applications. While not wholly related to venom therapy, Chang Wei and Dr Mohd Redzwan Sabran from the University of Putra Malaysia, discuss a family of fungal toxins called aflatoxins, its toxic effects, and how probiotics might have aflatoxin-reducing properties. Other highlights in this issue include a column by Dr Chen Min Wei, Consultant Surgeon from the National Neuroscience Institute, and Samuel Choo, Co-Founder and Head of Product at Kyalio, on how immersive virtual reality is bridging the gap between studying and performing surgery, and an interview with Andreas Joergensen, Managing Director of the SEA Cluster at Organon, on women’s healthcare and reproductive health awareness in Asia.","PeriodicalId":89742,"journal":{"name":"Asia-Pacific biotech news","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45138916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Revolutionising the Reproductive World (Vol. 26, No. 03n04, Full Issue) 《生殖世界的革命》（第26卷，第03n04期，全期）
Asia-Pacific biotech news Pub Date : 2022-03-01 DOI: 10.1142/s0219030322000039
{"title":"Revolutionising the Reproductive World (Vol. 26, No. 03n04, Full Issue)","authors":"","doi":"10.1142/s0219030322000039","DOIUrl":"https://doi.org/10.1142/s0219030322000039","url":null,"abstract":"For the months of March and April 2022, APBN looks at how we can improve and support women's reproductive health. In Features, we have Dr Samuel Prien and Dr Linsay Penrose from Texas Tech University Health Sciences on how we may select the best embryos that will provide the best chances for pregnancy; Dr Alok Javali and Dr Nicolas Rivron from IMBA-Institute of Molecular Biology in Vienna, Austria on how blastoids can be used as a drug discovery tool to improve IVF procedures; and Michelle Tan Min Shuen on reproductive genetic technology. In Columns, Sumir Bhatia, President, Asia Pacific, Lenovo Infrastructure Solutions Group talks about the future of genome sequencing and Justin Loh, Country Director for Singapore, Veritas Technologies tells us how we may protect patient data from data breaches. In Spotlights, we recap the highlights from the Future of Healthcare Week, discussing the path forward in a post-COVID world.","PeriodicalId":89742,"journal":{"name":"Asia-Pacific biotech news","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43188846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stronger, Better, Faster – Improving Cancer Treatment and Research (Vol. 26, No. 2, Full Issue) 更强、更好、更快——改善癌症治疗和研究(26卷第2期，全期)
Asia-Pacific biotech news Pub Date : 2022-01-26 DOI: 10.1142/s0219030322000027
{"title":"Stronger, Better, Faster – Improving Cancer Treatment and Research (Vol. 26, No. 2, Full Issue)","authors":"","doi":"10.1142/s0219030322000027","DOIUrl":"https://doi.org/10.1142/s0219030322000027","url":null,"abstract":"For the month of February 2022, APBN looks at the many ways research is paving the way for improved cancer treatment outcomes. In Features, Kenneth Tan, President of Asia-Pacific, Japan and India at Varian, shares how we can accelerate the path from cancer diagnosis to therapy, improving survivorship. Then, Lance Kawaguchi, CEO of Cure Brain Cancer Foundation, writes about the importance of cancer research, its challenges, and how the Foundation is working to support brain cancer research. For our last feature, we have Dr Ahmed Abdelal, Global Head Medical Affairs Interventional Imaging and North America Head of Medical & Regulatory Affairs, Guerbet and Dr Binta Patel, North America Medical Affairs Manager, Guerbet, to give us a treatment update for hepatocellular carcinoma. Other topics covered in this issue includes the importance of trust in the pharmaceutical industry and how companies can improve trust with technology-led transparency, how we may learn from the pandemic and better prepare for the next unknown crisis, a discussion on the incidence of Omicron and Delta variants in two case studies, and an interview with a spokesperson from Novartis on their newly approved cholesterol drug.","PeriodicalId":89742,"journal":{"name":"Asia-Pacific biotech news","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48595009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Discoveries and Innovations in Drug Development (Vol. 26, No. 1, Full Issue) 药物开发中的发现与创新(第26卷第1期)
Asia-Pacific biotech news Pub Date : 2021-12-28 DOI: 10.1142/s0219030322000015
{"title":"Discoveries and Innovations in Drug Development (Vol. 26, No. 1, Full Issue)","authors":"","doi":"10.1142/s0219030322000015","DOIUrl":"https://doi.org/10.1142/s0219030322000015","url":null,"abstract":"For the month of January 2022, APBN looks at some discoveries and innovation in pharmacology. In Features, Dr Harish Dave, Co-Founder and Chief Medical Officer of AUM Biosciences, discusses today's shifting paradigm in oncology drug development towards highly selective, minimally toxic, and patient-centric treatments, while Jade Pallett, Chief Technology Officer for Zoono UK & Europe, sheds light on how antimicrobial coatings outdo traditional methods of disinfection. Then, we have A/Prof Alexandra Sharland, Dr Nicole Mifsud, and Eric Son to elucidate how understanding antigen-specificity of host T cells can reduce organ transplantation rejection. Finally, in Spotlights, we have two interviews – one where we speak to Mr Willson Deng, CEO of Arcstone, on the role of digital technology in supporting MedTech manufacturing, and the other with Liu Qun, Head of IQVIA, China, where we learn more about the Chinese biopharmaceutical market.","PeriodicalId":89742,"journal":{"name":"Asia-Pacific biotech news","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45698401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Future of Us – Transforming Healthcare With Intelligent Machines (Vol. 25, No. 12, Full Issue) 我们的未来-用智能机器改变医疗保健(第25卷，第12期，全期)
Asia-Pacific biotech news Pub Date : 2021-12-01 DOI: 10.1142/s0219030321000124
{"title":"Future of Us – Transforming Healthcare With Intelligent Machines (Vol. 25, No. 12, Full Issue)","authors":"","doi":"10.1142/s0219030321000124","DOIUrl":"https://doi.org/10.1142/s0219030321000124","url":null,"abstract":"For the month of December 2021, APBN looks the applications of artificial intelligence and robotics in the healthcare space. In Features, we hear from Christopher Khang, President and CEO of GE Healthcare ASEAN, on how innovative technologies such as AI and automation are shaping a bright future for radiologists and their patients. Then, we have David Irecki from Boomi, who proposes that a unified view of patient data can enable holistic, coordinated services that will improve people'soverall quality of life, and an article contribution by Lewis Ho, Chief Executive Officer at Avalon SteriTech on innovative healthcare solutions and the future of smart cleaning. Shifting away from intelligent machines, we speak to Dr. Goh Choo Beng, Head of Medical Affairs at Takeda APAC, on unmet disease areas and learn more about the different treatments and trials currently in the pipeline at Takeda, and finally, we wrap up the year 2021 with Lu-Ching Lau, Director for External Affairs, Policy and Communications, Singapore and Malaysia, MSD, as she shares with us how we may navigate through current and future health challenges.","PeriodicalId":89742,"journal":{"name":"Asia-Pacific biotech news","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45878725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：604180095
Book学术官方微信
小红书