I. Elbinoune, B. Amine, S. Rostom, S. Shyen, D. Elbadri, M. Ezzahri, N. Mawani, F. Moussa, S. Gueddari, W. Moudjibou, M. Erraoui, J. Bahha, R. Abouqal, B. Chkirate, N. Hajjaj-Hassouni
{"title":"Discordance between physician's and parent's global assessments in juvenile idiopathic arthritis.","authors":"I. Elbinoune, B. Amine, S. Rostom, S. Shyen, D. Elbadri, M. Ezzahri, N. Mawani, F. Moussa, S. Gueddari, W. Moudjibou, M. Erraoui, J. Bahha, R. Abouqal, B. Chkirate, N. Hajjaj-Hassouni","doi":"10.5455/APR.101020160659","DOIUrl":"https://doi.org/10.5455/APR.101020160659","url":null,"abstract":"","PeriodicalId":89737,"journal":{"name":"Annals of paediatric rheumatology","volume":"31 1","pages":"71-78"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82440617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aseel Daghistani, C. Freychet, P. Pillet, J. Stéphan, O. Richer
{"title":"First line therapy by Interleukin-1 teceptor antagonist in steroid naive children with systemic juvenile idiopathic arthritis","authors":"Aseel Daghistani, C. Freychet, P. Pillet, J. Stéphan, O. Richer","doi":"10.5455/apr.122420170637","DOIUrl":"https://doi.org/10.5455/apr.122420170637","url":null,"abstract":"","PeriodicalId":89737,"journal":{"name":"Annals of paediatric rheumatology","volume":"19 1","pages":"78"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79753103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pediatric Behcet Disease","authors":"M. Çakan, N. Ayaz","doi":"10.5455/APR.092520172333","DOIUrl":"https://doi.org/10.5455/APR.092520172333","url":null,"abstract":"variable because can of any It is also considered as an autoinflammatory disorder because of the recurrent and mostly self-limited attacks the Abstract Behçet disease is an inflammatory disorder characterized by recurrent oral and genital ulcerations, uveitis, cutaneous, musculoskeletal, vascular, gastrointestinal and neurological manifestations. It is also classified as variable vessel vasculitis because it can affect any size and type of vessel in any part of the body. Mucocutaneous manifestations are the initial symptoms and signs in the majority of the cases but ocular, vascular and neurological manifestations are the leading causes of morbidity and mortality. The disease is rare in childhood and most commonly affects men between the ages of 20-40 years and follows a more severe course in males. The pathogenesis of the disease still remains obscure. The of Behçet disease Silk Far is based on the constellation of the clinical findings. Recurrent oral aphthosis is the most common initial finding but most children develop other diagnostic signs and symptoms of the disease many years later. There is no cure for Behçet disease and treatment is aimed at alleviating inflammation and vasculitis that is directed by major organ involvement. Colchicine is the mainstay of the therapy and immunosuppressive drugs like azathioprine, cyclosporine A, cyclophosphamide are used depending on the type and severity of the organ involved. Biological drugs, especially TNF-α inhibitors and interleukin-1 antagonists, seem to be showing promising results in resistant cases.","PeriodicalId":89737,"journal":{"name":"Annals of paediatric rheumatology","volume":"7 1","pages":"67"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88658521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cynthia K Manos, Rui Xiao, Timothy G Brandon, Jon M Burnham, Babette S Zemel, Pamela F Weiss
{"title":"Obesity and Pediatric Psoriatic Arthritis.","authors":"Cynthia K Manos, Rui Xiao, Timothy G Brandon, Jon M Burnham, Babette S Zemel, Pamela F Weiss","doi":"10.5455/apr.031320170835","DOIUrl":"https://doi.org/10.5455/apr.031320170835","url":null,"abstract":"<p><strong>Objective: </strong>Studies in adults have shown a significant association between obesity and psoriatic arthritis, however the association of obesity with pediatric psoriatic arthritis is unknown. We aimed to evaluate obesity in pediatric psoriatic arthritis.</p><p><strong>Methods: </strong>We conducted a cross-sectional study of children with psoriasis and psoriatic arthritis evaluated at a single center between 6/2010 and 9/2014. Two healthy reference populations were utilized: 1) local reference population from the surrounding community and 2) a national reference population derived from NHANES. Age and sex-specific z-scores for weight, height, and body mass index (BMI) were calculated. Differences in clinical and demographic characteristics between groups were assessed.</p><p><strong>Results: </strong>During the study period, 48 children with psoriatic arthritis and 231 patients with psoriasis were evaluated. Three (6.2%) and 5 (10.4%) of the children with psoriatic arthritis were overweight or obese, respectively. In comparison to the reference healthy groups and psoriasis patients, the mean BMI z-score of children with psoriatic arthritis was not statistically different. However, patients with psoriasis were more likely to be obese than the community reference population (p-value <0.001).</p><p><strong>Conclusions: </strong>Children with psoriasis were more obese than the healthy reference population, however there was no statistically significant difference in obesity between children with psoriatic arthritis and psoriasis or psoriatic arthritis and the reference population. This lack of association may be reflective of true differences in pediatric and adult-onset disease and warrants further investigation.</p>","PeriodicalId":89737,"journal":{"name":"Annals of paediatric rheumatology","volume":"6 2","pages":"34-40"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5455/apr.031320170835","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35999794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of the long-term outcome of treatment with corticosteroids and mycophenolate mofetil in juvenile onset severe lupus nephritis -A single center experience-","authors":"Tomoo Kise, H. Yoshimura, S. Fukuyama, M. Uehara","doi":"10.5455/APR061320171806","DOIUrl":"https://doi.org/10.5455/APR061320171806","url":null,"abstract":"","PeriodicalId":89737,"journal":{"name":"Annals of paediatric rheumatology","volume":"1 1","pages":"41"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77286956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zakiya Saleh Al Mosawi, Mohamed Baqer Altahoo, H. Malallah, Barrak Mousawi
{"title":"Current outcome of patients with juvenile idiopathic arthritis: Clinical assessment, Disease activity, Functional ability and Articular and Extra-Articular damage.","authors":"Zakiya Saleh Al Mosawi, Mohamed Baqer Altahoo, H. Malallah, Barrak Mousawi","doi":"10.5455/APR.050520170659","DOIUrl":"https://doi.org/10.5455/APR.050520170659","url":null,"abstract":"Objective: To investigate the impact of chronic arthritis on children with juvenile idiopathic arthritis ( JIA) after five years of illness by using Childhood Assessment Quality of Life (CHAQ). And to evaluate the consistency of the clinical and patient’s assessment factors used in CHAQ. Methods: A Cross sectional study to assess patients who had JIA for five years or more. Clinical assessment, Disease activity status, CHAQ disability index (CHAQ-DI), Health-related quality of life (HRQOL) were assessed. Juvenile arthritis damage index for articular ( JADIA) and Extra-articular ( JADIE) were considered. The correlations of different CHAQ factors scores, the effect of duration of disease (DOD) on CHAQ-DI were statistically assessed. Results: 74 patients with JIA were enrolled for the study. JIA category; Oligo: 36, Poly: 19, Systemic: 7 and Enthesitis related arthritis (ERA): 12. Patients with systemic-JIA reported more disease activity than other categories. JADIE showed uveitis, mainly in Oligo (30.5%). The inter-correlation of different CHAQ indicators value was statistically significant. However there was no significant effect of DOD on CHAQ-DI score. Conclusion: CHAQ scores in our patients with JIA after 5 years of illness weighs the same values as in other studies. The HRQOL in JIA doesn’t significantly change after five years of the illness. Moreover, clinical indicators in CHAQ have an effect on other CHAQ arms after 5 years of illness.","PeriodicalId":89737,"journal":{"name":"Annals of paediatric rheumatology","volume":"5 1","pages":"1"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82092347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Afebrile Kawasaki Disease, Severe Cardiovascular Disease and Sudden Death in Infants","authors":"L. B. Gámez-González, M. Yamazaki-Nakashimada","doi":"10.5455/APR.031320170836","DOIUrl":"https://doi.org/10.5455/APR.031320170836","url":null,"abstract":"","PeriodicalId":89737,"journal":{"name":"Annals of paediatric rheumatology","volume":"8 1","pages":"10"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81495081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ma Mahdi, H. Rkain, M. Rkain, I. Bouaddi, F. Allali, M. Khorassani, N. Hajjaj-Hassouni
{"title":"The impact of chronic hemophilic arthropathy on children school life","authors":"Ma Mahdi, H. Rkain, M. Rkain, I. Bouaddi, F. Allali, M. Khorassani, N. Hajjaj-Hassouni","doi":"10.5455/APR.090720171728","DOIUrl":"https://doi.org/10.5455/APR.090720171728","url":null,"abstract":"","PeriodicalId":89737,"journal":{"name":"Annals of paediatric rheumatology","volume":"30 1","pages":"62"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84372905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cervical arthritis as presentation of oligoarticular juvenile idiopathic arthritis","authors":"R. Coutinho, P. Estanqueiro, C. Alves, M. Salgado","doi":"10.5455/apr.022720171305","DOIUrl":"https://doi.org/10.5455/apr.022720171305","url":null,"abstract":"Introduction The cervical spine (CS) is commonly affected in juvenile idiopathic arthritis ( JIA), especially in systemic and polyarticular subtypes [1-4], usually as a late complication [1-3]. In the first 6 months of JIA, CS is seldom involved and even less as single arthritis [1,5]. CS is rarely affected in the first 1-2 years from the onset of JIA [1]. In oligoarticular JIA (oJIA), cervical arthritis is also rare over the course of the disease [1,2,4], being exceptional as presentation [1,2,4,5]. We report a oJIA case with cervical arthritis as single manifestation for at least 48 months. Additionally, we describe our experience with two similar oJIA cases, and perform a literature review of this special presentation of oJIA. Case Report A 5-year-old boy, previously healthy, was admitted to our Emergency Room (ER) few hours after arriving from a long-term flight, due to a progressively worsening torticollis, started 4 weeks before. He had severe limitation of all the CS movements, with his head leaned to right side. Torticollis was non-painful during the first two weeks of illness. Then, the child started complaining of moderate neck pain, worse on waking and improving Abstract","PeriodicalId":89737,"journal":{"name":"Annals of paediatric rheumatology","volume":"18 1","pages":"5"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85250005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Salivary cortisol level as a marker of adrenal function in children with systemic inflammatory response syndrome in Egypt.","authors":"A. Elbaih, Amany elkilany, Maha M. Enany","doi":"10.5455/APR.022720171311","DOIUrl":"https://doi.org/10.5455/APR.022720171311","url":null,"abstract":"Introduction: Pediatric systemic inflammatory response syndrome (SIRS) criteria is widely used to identify patients who need specialized, advanced therapies. Cortisol plays an important anti-inflammatory in SIRS. Adrenal status and use of corticosteroid in children with SIRS still controversial. Objective: to assess salivary in children with SIRS and its relation to outcome in PICU of Suez Canal University hospital. Methods: prospective case control study was carried out. We analyzed 45 patients with SIRS and45 healthy control children for morning salivary and total serum cortisol level Results: children with SIRS have significantly higher morning salivary and total serum cortisol level than control group (p=.00). Mortality was associated with higher levels of both salivary and total cortisol. Conclusions: Salivary cortisol can be used to estimate cortisol levels in pediatric with SIRS and can foretell outcome. Keywords: systemic inflammatory response syndrome, children, salivary, cortisol.","PeriodicalId":89737,"journal":{"name":"Annals of paediatric rheumatology","volume":"105 1","pages":"28-33"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83515358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}