{"title":"Item Response Theory Analysis to Assess Dimensionality of Substance Use Disorder Abuse and Dependence Symptoms.","authors":"L. Kirisci, R. Tarter, M. Reynolds, M. Vanyukov","doi":"10.5750/IJPCM.V6I4.613","DOIUrl":"https://doi.org/10.5750/IJPCM.V6I4.613","url":null,"abstract":"BACKGROUND Item response theory (IRT) based studies conducted on diverse samples showed a single dominant factor for DSM-III-R and DSM-IV substance use disorder (SUD) abuse and dependence symptoms of alcohol, cannabis, sedative, cocaine, stimulants, and opiates use disorders. IRT provides the opportunity, within a person-centered framework, to accurately gauge each person's severity of disorder that, in turn, informs required intensiveness of treatment. OBJECTIVES The aim of this study was to determine whether the SUD symptoms indicate a unidimensional trait or instead need to be conceptualized and quantified as a multidimensional scale. METHODS The sample was composed of families of adult SUD+ men (n=349), and SUD+ women (n=173), who qualified for DSM-III-R diagnosis of substance use disorder (abuse or dependence) and families of adult men and women who did not qualify for a SUD diagnosis (SUD- men: n=190, SUD- women: n=133). An expanded version of the Structured Clinical Interview for DSM-III-R (SCID) was administered to characterize lifetime and current substance use disorders. Item response theory methodology was used to assess the dimensionality of DSM-III-R SUD abuse and dependence symptoms. RESULTS A bi-factor model provided the optimal representation of the factor structure of SUD symptoms in males and females. SUD symptoms are scalable as indicators of a single common factor, corresponding to general (non-drug-specific, common) liability to addiction, combined with drug-specific liabilities. CONCLUSIONS IRT methodology used to quantify the continuous general liability to addiction (GLA) latent trait in individuals having SUD symptoms was found effective for accurately measuring SUD severity in men and women. This may be helpful for person-centered medicine approaches to effectively address intensity of treatment.","PeriodicalId":89680,"journal":{"name":"International journal of person centered medicine","volume":"1 1","pages":"260-273"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86534097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Introduction to Metrics in Person Centered Medicine Research.","authors":"L. Kirisci, M. Vanyukov, J. Mezzich","doi":"10.5750/IJPCM.V6I4.611","DOIUrl":"https://doi.org/10.5750/IJPCM.V6I4.611","url":null,"abstract":"The articulation of science and humanism is at the core of Person Centered Medicine (PCM). Thus, applying the scientific method to advance our understanding of health and the improvement of health actions towards the fulfillment of the whole person is a permanent concern of PCM .","PeriodicalId":89680,"journal":{"name":"International journal of person centered medicine","volume":"238 1","pages":"248-249"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73267547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Levent Kirisci, Ralph E Tarter, Maureen Reynolds, Michael M Vanyukov
{"title":"Item Response Theory Analysis to Assess Dimensionality of Substance Use Disorder Abuse and Dependence Symptoms.","authors":"Levent Kirisci, Ralph E Tarter, Maureen Reynolds, Michael M Vanyukov","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Item response theory (IRT) based studies conducted on diverse samples showed a single dominant factor for DSM-III-R and DSM-IV substance use disorder (SUD) abuse and dependence symptoms of alcohol, cannabis, sedative, cocaine, stimulants, and opiates use disorders. IRT provides the opportunity, within a person-centered framework, to accurately gauge each person's severity of disorder that, in turn, informs required intensiveness of treatment.</p><p><strong>Objectives: </strong>The aim of this study was to determine whether the SUD symptoms indicate a unidimensional trait or instead need to be conceptualized and quantified as a multidimensional scale.</p><p><strong>Methods: </strong>The sample was composed of families of adult SUD+ men (n=349), and SUD+ women (n=173), who qualified for DSM-III-R diagnosis of substance use disorder (abuse or dependence) and families of adult men and women who did not qualify for a SUD diagnosis (SUD- men: n=190, SUD- women: n=133). An expanded version of the Structured Clinical Interview for DSM-III-R (SCID) was administered to characterize lifetime and current substance use disorders. Item response theory methodology was used to assess the dimensionality of DSM-III-R SUD abuse and dependence symptoms.</p><p><strong>Results: </strong>A bi-factor model provided the optimal representation of the factor structure of SUD symptoms in males and females. SUD symptoms are scalable as indicators of a single common factor, corresponding to general (non-drug-specific, common) liability to addiction, combined with drug-specific liabilities.</p><p><strong>Conclusions: </strong>IRT methodology used to quantify the continuous general liability to addiction (GLA) latent trait in individuals having SUD symptoms was found effective for accurately measuring SUD severity in men and women. This may be helpful for person-centered medicine approaches to effectively address intensity of treatment.</p>","PeriodicalId":89680,"journal":{"name":"International journal of person centered medicine","volume":"6 4","pages":"260-273"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5606209/pdf/nihms850104.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35440137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Introduction to Metrics in Person Centered Medicine Research.","authors":"Levent Kirisci, Michael Vanyukov, Juan E Mezzich","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":89680,"journal":{"name":"International journal of person centered medicine","volume":"6 4","pages":"248-249"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699216/pdf/nihms-850098.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35286584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Cloninger, L. Salvador-Carulla, Laurence J. Kirmayer, M. Schwartz, J. Appleyard, N. Goodwin, J. Groves, M. Hermans, J. Mezzich, C. V. Van Staden, S. Rawaf
{"title":"A Time for Action on Health Inequities: Foundations of the 2014 Geneva Declaration on Person- and People-centered Integrated Health Care for All.","authors":"C. Cloninger, L. Salvador-Carulla, Laurence J. Kirmayer, M. Schwartz, J. Appleyard, N. Goodwin, J. Groves, M. Hermans, J. Mezzich, C. V. Van Staden, S. Rawaf","doi":"10.5750/IJPCM.V4I2.472","DOIUrl":"https://doi.org/10.5750/IJPCM.V4I2.472","url":null,"abstract":"Global inequalities contribute to marked disparities in health and wellness of human populations. Many opportunities now exist to provide health care to all people in a person- and people-centered way that is effective, equitable, and sustainable. We review these opportunities and the scientific, historical, and philosophical considerations that form the basis for the International College of Person-centered Medicine's 2014 Geneva Declaration on Person- and People-centered Integrated Health Care for All. Using consistent time-series data, we critically examine examples of universal healthcare systems in Chile, Spain, and Cuba. In a person-centered approach to public health, people are recognized to have intrinsic dignity and are treated with respect to encourage their developing health and happiness. A person-centered approach supports the freedom and the responsibility to develop one's life in ways that are personally meaningful and that are respectful of others and the environment in which we live together. Evidence suggests that health care organizations function well when they operate in a person-and people-centered way because that stimulates better coordination, cooperation, and social trust. Health care coverage must be integrated at several interconnected levels in order to be effective, efficient, and fair. To reduce the burden of disease, integration is needed between the people seeking and delivering care, within the social network of each person, across the trajectory of each person's life, among primary caregivers and specialists, and across multiple sectors of society. For integration to succeed across all these levels, it must foster common values and a shared vision of the future.","PeriodicalId":89680,"journal":{"name":"International journal of person centered medicine","volume":"57 1","pages":"69-89"},"PeriodicalIF":0.0,"publicationDate":"2015-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90708459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C Robert Cloninger, Luis Salvador-Carulla, Laurence J Kirmayer, Michael A Schwartz, James Appleyard, Nick Goodwin, JoAnna Groves, Marc H M Hermans, Juan E Mezzich, C W van Staden, Salman Rawaf
{"title":"A Time for Action on Health Inequities: Foundations of the 2014 Geneva Declaration on Person- and People-centered Integrated Health Care for All.","authors":"C Robert Cloninger, Luis Salvador-Carulla, Laurence J Kirmayer, Michael A Schwartz, James Appleyard, Nick Goodwin, JoAnna Groves, Marc H M Hermans, Juan E Mezzich, C W van Staden, Salman Rawaf","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Global inequalities contribute to marked disparities in health and wellness of human populations. Many opportunities now exist to provide health care to all people in a person- and people-centered way that is effective, equitable, and sustainable. We review these opportunities and the scientific, historical, and philosophical considerations that form the basis for the International College of Person-centered Medicine's 2014 <i>Geneva Declaration on Person- and People-centered Integrated Health Care for All.</i> Using consistent time-series data, we critically examine examples of universal healthcare systems in Chile, Spain, and Cuba. In a person-centered approach to public health, people are recognized to have intrinsic dignity and are treated with respect to encourage their developing health and happiness. A person-centered approach supports the freedom and the responsibility to develop one's life in ways that are personally meaningful and that are respectful of others and the environment in which we live together. Evidence suggests that health care organizations function well when they operate in a person-and people-centered way because that stimulates better coordination, cooperation, and social trust. Health care coverage must be integrated at several interconnected levels in order to be effective, efficient, and fair. To reduce the burden of disease, integration is needed between the people seeking and delivering care, within the social network of each person, across the trajectory of each person's life, among primary caregivers and specialists, and across multiple sectors of society. For integration to succeed across all these levels, it must foster common values and a shared vision of the future.</p>","PeriodicalId":89680,"journal":{"name":"International journal of person centered medicine","volume":"4 2","pages":"69-89"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485425/pdf/nihms689648.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34260566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Person-centered Health Promotion in Chronic Disease.","authors":"C Robert Cloninger","doi":"10.5750/ijpcm.v3i1.379","DOIUrl":"10.5750/ijpcm.v3i1.379","url":null,"abstract":"<p><p>Health promotion must be person-centered, not organ- or disease-centered, in order to be effective because physical, mental, social, and spiritual aspects of human functioning are inextricably intertwined. Chronic medical disorders, such as heart disease, chronic obstructive pulmonary disease, diabetes, cancer, asthma, and arthritis, are strongly associated with immature personality, emotional instability, and social dysfunction. All indicators of physical, mental, and social well-being are strongly related to the level of maturity and integration of personality, so personality is a useful focus for the promotion of well-being. Assessment of personality also facilitates the awareness of the clinician and the patient about the patient's strengths, weaknesses, and goals, thereby contributing to an effective therapeutic alliance. Health, well-being, resilience, and recovery of function all involve increasing levels of the character traits of Self-directedness, Cooperativeness, and Self-transcendence. Person-centered programs that enhance self-regulation of functioning to achieve personally valued goals improve compliance with medical treatment and quality of life in people with chronic disease. Effective therapeutic approaches to health promotion activate a complex adaptive system of feedback interactions among functioning, plasticity, and virtuous ways of thinking and acting. The probability of personality change can be predicted by high levels of Self-transcendence, which give rise to an outlook of unity and connectedness, particularly when combined with the temperament traits of high Novelty Seeking and high Persistence. In summary, person-centered psychobiological treatments that facilitate the development of well-being and personality development are crucial in the prevention, treatment, and rehabilitation of chronic medical diseases.</p>","PeriodicalId":89680,"journal":{"name":"International journal of person centered medicine","volume":"3 1","pages":"5-12"},"PeriodicalIF":0.0,"publicationDate":"2013-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5750/ijpcm.v3i1.379","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34044372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Quick Screen to Detect Current and Future Substance Use Disorder in Female Adolescents.","authors":"Levent Kirisci, Maureen Reynolds, Ralph Tarter","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Prevention of substance use disorder (SUD) is impeded by the large number, complexity and idiosyncratic configuration of etiological factors. Effective prevention of SUD is feasible however when intervention resources are prioritized to individuals who are objectively determined as high risk and tailored to their specific characteristics and circumstances.</p><p><strong>Objective: </strong>This study had the aim of developing a rapid accurate screening instrument for determining current presence of and future risk for SUD.</p><p><strong>Methods: </strong>The sample consisted of 182 girls recruited when they were 10-12 years of age and tracked to 22 years of age. From a large item pool the Drug Use Screening Inventory Quick Screen for Females (DQS-F) was derived consisting of the <i>Substance Involvement Index</i> and the <i>Problem Severity Index</i>.</p><p><strong>Results: </strong>The DQS for Females (DQS-F) has high sensitivity for identifying girls who currently qualify for SUD diagnosis. Furthermore, accuracy of predicting future SUD with the DQS-F is in the good range at age 16 and in the very good range at age 19.</p><p><strong>Conclusions: </strong>Requiring only three minutes for administration on the Web the DQS-F is an efficient method for identifying girls requiring thorough assessment prior to implementing individualized intervention.</p>","PeriodicalId":89680,"journal":{"name":"International journal of person centered medicine","volume":"3 4","pages":"280-285"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115676/pdf/nihms603520.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32557619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"People Create Health: Effective Health Promotion is a Creative Process.","authors":"C Robert Cloninger, Kevin M Cloninger","doi":"10.5750/ijpcm.v3i2.399","DOIUrl":"10.5750/ijpcm.v3i2.399","url":null,"abstract":"<p><p>Effective health promotion involves the creative cultivation of physical, mental, social, and spiritual well-being. Efforts at health promotion produce weak and inconsistent benefits when it does not engage people to express their own goals and values. Likewise, health promotion has been ineffective when it relies only on instruction about facts regarding a healthy lifestyle, or focuses on reduction of disease rather than the cultivation of well-being. Meta-analysis of longitudinal studies and experimental interventions shows that improvements in subjective well-being lead to short-term and long-term reductions in medical morbidity and mortality, as well as to healthier functioning and longevity. However, these effects are inconsistent and weak (correlations of about 0.15). The most consistent and strong predictor of both subjective well-being and objective health status in longitudinal studies is a creative personality profile characterized by being highly self-directed, cooperative, and self-transcendent. There is a synergy among these personality traits that enhances all aspects of the health and happiness of people. Experimental interventions to cultivate this natural creative potential of people are now just beginning, but available exploratory research has shown that creativity can be enhanced and the changes are associated with widespread and profound benefits, including greater physical, mental, social, and spiritual well-being. In addition to benefits mediated by choice of diet, physical activity, and health care utilization, the effect of a creative personality on health may be partly mediated by effects on the regulation of heart rate variability. Creativity promotes autonomic balance with parasympathetic dominance leading to a calm alert state that promotes an awakening of plasticities and intelligences that stress inhibits. We suggest that health, happiness, and meaning can be cultivated by a complex adaptive process that enhances healthy functioning, plasticity and self-transcendent values. Health promotion is likely to have only weak and consistent benefits unless it is person-centered and thereby helps people to learn to live more creatively.</p>","PeriodicalId":89680,"journal":{"name":"International journal of person centered medicine","volume":"3 2","pages":"114-122"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540224/pdf/nihms-696232.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34109640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luis Salvador-Carulla, C Robert Cloninger, Amalia Thornicroft, Juan E Mezzich
{"title":"Background, Structure and Priorities of the 2013 Geneva Declaration on Person-centered Health Research.","authors":"Luis Salvador-Carulla, C Robert Cloninger, Amalia Thornicroft, Juan E Mezzich","doi":"10.5750/ijpcm.v3i2.401","DOIUrl":"10.5750/ijpcm.v3i2.401","url":null,"abstract":"<p><p>Declarations are relevant tools to frame new areas in health care, to raise awareness and to facilitate knowledge-to-action. The International College on Person Centered Medicine (ICPCM) is seeking to extend the impact of the ICPCM Conference Series by producing a declaration on every main topic. The aim of this paper is to describe the development of the 2013 Geneva Declaration on Person-centered Health Research and to provide additional information on the research priority areas identified during this iterative process. There is a need for more PCM research and for the incorporation of the PCM approach into general health research. Main areas of research focus include: Conceptual, terminological, and ontological issues; research to enhance the empirical evidence of PCM main components such as PCM informed clinical communication; PCM-based diagnostic models; person-centered care and interventions; and people-centered care, research on training and curriculum development. Dissemination and implementation of PCM knowledge-base is integral to Person-centered Health Research and shall engage currently available scientific and translational dissemination tools such journals, events and eHealth.</p>","PeriodicalId":89680,"journal":{"name":"International journal of person centered medicine","volume":"3 2","pages":"109-113"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487411/pdf/nihms696235.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33880157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}