British journal of medical & surgical urology最新文献

{"title":"Typical Aspects of the \"Mastic Kidney\" Suggestive of Renal Tuberculosis","authors":"I. Ziani, Jihad Lakssir, S. Derqaoui, H. Dergamoun, A. Ibrahimi, F. Zouidia, H. Sayegh, L. Benslimane, Y. Nouini","doi":"10.35248/2168-9857.20.9.228","DOIUrl":"https://doi.org/10.35248/2168-9857.20.9.228","url":null,"abstract":"Tuberculosis remains a priority public health problem for the World Health Organization (WHO), The difficulty of often late diagnosis and the seriousness of lesions caused by BK even after anti-bacillary treatment, explains the seriousness of the disease with a high number of nephrectomies. The clinical pictures can be misleading, hence the advantage of making this diagnosis before any recurring urological symptom. In our observation, the diagnosis was mentioned in the face of the appearance of the \"mastic kidney\" indicates an already advanced stage of the pathology, after the anti bacillary treatment, the ablative surgical treatment takes place for the treatment sometimes serious consequences.","PeriodicalId":89536,"journal":{"name":"British journal of medical & surgical urology","volume":"24 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75177000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MicroRNA-100 expression correlation with clincopathological parameters in bladder cancer","authors":"Manjeet Kumar","doi":"10.24105/2168-9857.8.224","DOIUrl":"https://doi.org/10.24105/2168-9857.8.224","url":null,"abstract":"Objective: - Bladder carcinoma is one of the most common tumors in the world and, despite the therapy currently available, most of the patients relapse. MicroRNA- 100 is down regulated in bladder cancer tissue in comparison to normal tissue; however, clinical significance of miR-100 in human bladder cancer has not been elucidated. The aim of study was to correlate miR 100 expression levels with tumor grade, stage and recurrence. Methods: - Expression of miR-100 in 26 pairs of bladder cancer and adjacent normal tissues were analysed by Sybergreen RT-PCR. The expression levels of miR 100 in tumor and normal were normalised with 18s gene. The expression levels of miR 100 expression were analysed in fold change (DDCT method). The difference between groups were analysed by student t test and Anova. Results: - Downregulation of miR-100 expression in tumor was an important finding in our study. MiR-100 expression were decreased (n=24) in tumour tissue in comparison with normal bladder urothelium. Mean expression of miR-100(fold change) was 0.33+/-0.35 and significantly decreased on comparison to normal (1) (p=0.001) There is no correlation of miR-100 expression levels with gender and age (p=0.583). Mean expression of miR-100 in low grade was 0.41+/-0.38 whereas in high grade 0.22+/-0.26 (p=0.182). Ta tumors had mean (fold change) 0.42+/- 0.39, T1 had mean value of 0.25 +/- 0.30 and T 2 had mean value of 0.24 +/- 0.30.(p=0.463) miR-100 expression levels were decreased in MIBC(T2) more than NMIBC (Ta,T1) (p=0.473).Mean levels 2^-DDCT (fold change) in recurrent tumors were 0.16+/-0.19 whereas fold change in nonrecurring tumors was 0.40 +/-0.38.(p=0.045) 1 patient with T2 tumor underwent progression with all patients surviving till end of study. Conclusions miR-100 expression is down regulated in Bladder cancer tissue than normal bladder urothelium. The miR-100 expression levels were decreased in all bladder tumors however reaching significance in recurrent bladder tumor, suggesting use of miR 100 as potential marker for further risk stratification and prognosis in treatment of urinary bladder cancer.","PeriodicalId":89536,"journal":{"name":"British journal of medical & surgical urology","volume":"133 7 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79625316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bilateral Obstructive Uropathy Due to Spontaneously a Large Rectus Sheath Hematoma in a Patient on Anticoagulant Treatment","authors":"O. Dede","doi":"10.35248/2168-9857.19.8.214","DOIUrl":"https://doi.org/10.35248/2168-9857.19.8.214","url":null,"abstract":"Rectus sheath haematomas associated with anticoagulation are often self-limiting. When large, however, they can even extend into the pelvis and cause compression of adjacent organs. A 54-year-old female on treatment Coumadin; during her hospitalisation, she developed a spontaneous rectus abdominis haematoma and occurred bilateral obstructive uropathy. A large rectus sheath haematoma that extends into the bladder causing renal obstruction can be treated by minimale invasive surgery.","PeriodicalId":89536,"journal":{"name":"British journal of medical & surgical urology","volume":"28 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76036286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation of miR-100 Expression with Clinopathological Parameters in Bladder Cancer","authors":"Manjeet Kumar, Santosh Kumar, S. Singh, R. Prasad, Aman Kumar","doi":"10.35248/2168-9857.20.9.230","DOIUrl":"https://doi.org/10.35248/2168-9857.20.9.230","url":null,"abstract":"Objective: Bladder carcinoma is one of the most common tumors in the world and, despite the therapy currently available, most of the patients relapse. MicroRNA- 100 is down regulated in bladder cancer tissue in comparison to normal tissue; however, clinical significance of miR-100 in human bladder cancer has not been elucidated. The aim of study was to correlate miR 100 expression levels with tumor grade, stage and recurrence. Methods: Expression of miR-100 in 26 pairs of bladder cancer and adjacent normal tissues were analysed by Sybergreen RT-PCR. The expression levels of miR 100 in tumor and normal were normalised with 18s gene. The expression levels of miR 100 expression were analysed in fold change (DDCT method). The difference between groups were analysed by student t test and Anova. Results: Downregulation of miR-100 expression in tumor was an important finding in our study. MiR-100 expression were decreased (n=24) in tumour tissue in comparison with normal bladder urothelium. Mean expression of miR-100(fold change) was 0.33 ± 0.35 and significantly decreased on comparison to normal (p=0.001). There is no correlation of miR-100 expression levels with gender and age (p=0.583). Mean expression of miR-100 in low grade was 0.41 ± 0.38 whereas in high grade 0.22 ± 0.26 (p=0.182). Ta tumors had mean (fold change) 0.42 ± 0.39, T1 had mean value of 0.25 ± 0.30 and T 2 had mean value of 0.24 ± 0.30.(p=0.463) miR-100 expression levels were decreased in MIBC(T2) more than NMIBC (Ta,T1) (p=0.473).Mean levels 2^-DDCT (fold change) in recurrent tumors were 0.16 ± 0.19 whereas fold change in nonrecurring tumors was 0.40 ± 0.38.(p=0.045) 1 patient with T2 tumor underwent progression with all patients surviving till end of study. Conclusions: miR-100 expression is down regulated in Bladder cancer tissue than normal bladder urothelium. The miR-100 expression levels were decreased in all bladder tumors however reaching significance in recurrent bladder tumor, suggesting use of miR 100 as potential marker for further risk stratification and prognosis in treatment of urinary bladder cancer.","PeriodicalId":89536,"journal":{"name":"British journal of medical & surgical urology","volume":"356 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82616719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editor's Note on Medical & Surgical Urology","authors":"A. Barqawi","doi":"10.35248/2168-9857.20.9.E101","DOIUrl":"https://doi.org/10.35248/2168-9857.20.9.E101","url":null,"abstract":"","PeriodicalId":89536,"journal":{"name":"British journal of medical & surgical urology","volume":" 728","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72378285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Voiding Troubles, Fecal Incontinence and Anal Intercourse","authors":"A. E. Hemaly, L. Mousa","doi":"10.24105/2168-9857.9.232","DOIUrl":"https://doi.org/10.24105/2168-9857.9.232","url":null,"abstract":"Voiding (urine &/or feces) depends on: Toilet training early in life switch voiding from uncontrolled CNS-pelvic parasympathetic action to voluntary CNSthoracolumbar sympathetic act. The IAS is a collagen-muscle tissue cylinder that surround the anal canal. The IAS consists mainly of strong collagen tissue cylinder mixed with smooth plain muscle fibers with its nerve supply from the autonomic nervous system. It is surrounded in its lower part with the voluntary striated muscle, the external anal sphincter (EAS). The IUS is a collagen-plain muscle tissue cylinder that extends from the bladder neck to the perineal membrane in both sex. The external urethral sphincter is a striated voluntary muscle lying in the deep perineal pouch. Voiding training induces and keeps high alpha-sympathetic tone at both the IUS & the IAS to maintain both contracted all the time, thus keeping the urethra & the anal canal empty and closed. On desire &/or need the person lowers the high alpha sympathetic tone at the IUS &/or the IAS to open the urethra &/ or the anal canal to void. Injury of the IAS leads to fecal incontinence (FI). The injury is mostly traumatic from childbirth trauma (CBT) but it can be the result of anal intercourse. Subsequently the presence of excreta in the open anal canal will induce sense of desire to void; it may give false impression of desire to void urine (OAB). Homosexuality &/or voiding incontinence are an important cause of psychological ailment.","PeriodicalId":89536,"journal":{"name":"British journal of medical & surgical urology","volume":"46 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77327873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Urodynamic Changes with Age in Boys with Posterior Urethral Valves","authors":"S. Wani, Viney Jadhav, N. Munianjana","doi":"10.35248/2168-9857.20.9.236","DOIUrl":"https://doi.org/10.35248/2168-9857.20.9.236","url":null,"abstract":"Introduction: Bladder dysfunction is a common cause of morbidity in posterior urethral valve (PUV) patients and urodynamic study provides a useful tool to identify the bladder dysfunction. The aim of this study was to evaluate the urodynamic patterns in different age groups in PUV patients. Material and Methods: Toilet trained patients more than 4 years of age were included in the study. Invasive urodynamic study was done in all patients. Patients were divided in to the three groups; Group-1 (4-8 years), group-2 (9-13 years) and group-3 (14-18 years). Various urodynamic parameters which were noted in each patient include compliance, bladder stability, bladder capacity, detrusor pressure during voiding, detrusor sphincter dysynergia and post void residue. Results: 47 patients were included in the study. Age of patients ranged from 4 years to 17.8 years with mean age of 6.4 years. Bladder hyperreflexia (14.3% in group-1, 14.3% in group-2 and 8.3% in group-3), poor compliance (9.5% in group-1, 28.6% in group-2 and 41.7% in group-3), bladder capacity (normal in 76.2% group-1, 50.0% in group-2 and 33.3% in group-3), (decreased in 14.3% group-1, 28.6% in group-2 and 16.7% in group-3) and (increased in 9.5% group-1, 21.4% in group-2 and 50.0% in group-3), detrusor pressure during voiding (sustained in 42.5% group-1, 42.8% in group-2 and 25.0% in group-3), (waxing and waning in 28.6% group-1, 28.6% in group-2 and 41.7% in group-3) and myogenic failure in 14.3% group-1, 21.4% in group-2 and 33.3% in group-3. Conclusion: Urodynamic pattern shows considerable overlap during childhood and through adolescence with hyper contractility generally seen in young children and hypo contractility and myogenic failure in older boys.","PeriodicalId":89536,"journal":{"name":"British journal of medical & surgical urology","volume":"3 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88737151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editor Note on Instruction to Authors: Medical and Surgical Urology","authors":"A. Traoré","doi":"10.35248/2168-9857.20.9.E102","DOIUrl":"https://doi.org/10.35248/2168-9857.20.9.E102","url":null,"abstract":"","PeriodicalId":89536,"journal":{"name":"British journal of medical & surgical urology","volume":"1 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88824946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Kidney Angiomyolipoma with Inferior Vena Cava Thrombosis during Third Trimester of Pregnancy","authors":"H. Bkiyar, I. Alouani, M. Gharibi, I. Skikar, B. Housni","doi":"10.35248/2168-9857.19.8.218","DOIUrl":"https://doi.org/10.35248/2168-9857.19.8.218","url":null,"abstract":"Kidney angiomyolipoma is a rare renal benign neoplasm. In exceptional cases, it can extend to inferior vena cava causing thrombosis. We report here a case of a 33 years old patient who presented an angiomyolipoma caval thrombus during pregnancy.","PeriodicalId":89536,"journal":{"name":"British journal of medical & surgical urology","volume":"37 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81441225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of Muscle Invasive Urothelial Bladder Cancer- A Review of the Literature","authors":"Ayun Kotokai Cassell III, B. Yunusa, M. Mbodji, M. Jalloh, A. Diallo, Y. Diallo, I. Labou, L. Niang, S. Gueye","doi":"10.24105/2168-9857.8.223","DOIUrl":"https://doi.org/10.24105/2168-9857.8.223","url":null,"abstract":"Carcinoma of the bladder is the fourth and fifth most frequently diagnosed cancer in the United States and Europe respectively. Muscle-Invasive Urothelial Bladder Cancer (MIBC) (cT2-T4) is an aggressive disease with poor 5-year Overall Survival (OS) of 50%. Epidemiological studies are unavailable in most African countries; however, Africa was found to have a lower incidence. Current optimal management is based on Radical Cystectomy (RC) and pelvic Lymph Node Dissection (LND), generally associated with pre-operative cisplatin-based chemotherapy. Adjuvant chemotherapy may be necessary in patients who did not benefit from neoadjuvant chemotherapy. A selected few patients who desire bladder preservation may benefit from bladder sparing procedures but should be cautioned about the risk of recurrence. The African literature lacks structured prospective studies on the management of urothelial muscle invasive bladder cancer and much of the clinical data are extrapolated from current evidence-based guidelines.","PeriodicalId":89536,"journal":{"name":"British journal of medical & surgical urology","volume":"19 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89441326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}