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A Review of Recent Advances in Upper Extremity Orthoses for Rehabilitation Therapy and Improved Functional Independence 上肢矫形器用于康复治疗和改善功能独立性的最新进展综述
Recent patents on biomedical engineering Pub Date : 2012-11-30 DOI: 10.2174/1874764711205030200
A.H. Hoffman
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引用次数: 1
Review of Recent Patents on Foldable Ventricular Assist Devices 可折叠心室辅助装置最新专利综述
Recent patents on biomedical engineering Pub Date : 2012-11-30 DOI: 10.2174/1874764711205030208
Po-Lin Hsu, M. McIntyre, Maximilian Kuetting, J. Parker, Christina Egger, R. Autschbach, T. Schmitz-Rode, U. Steinseifer
{"title":"Review of Recent Patents on Foldable Ventricular Assist Devices","authors":"Po-Lin Hsu, M. McIntyre, Maximilian Kuetting, J. Parker, Christina Egger, R. Autschbach, T. Schmitz-Rode, U. Steinseifer","doi":"10.2174/1874764711205030208","DOIUrl":"https://doi.org/10.2174/1874764711205030208","url":null,"abstract":"Abstract: Congestive heart failure accounts for a high morbidity worldwide. The only effective treatment for end-stage patients is heart transplantation or, in light of the shortage of suitable donors, an artificial heart or ventricular assist device (VAD). The newer-generation continuous-flow rotary VADs allow for a significant reduction in size and an improvement in reliability. However, the invasive implantation still limits this technology from being offered to critically ill patients. To benefit more heart failure patients, there is a need to develop a long-term VAD which can be implanted via minimally in-vasive procedure. Recently, expandable/deployable devices have been investigated as a potential solution. Such a device can be inserted percutaneously via the peripheral vessels in its collapsed form and operate in its expanded form at the de-sired location. This paper reviews significant patents on foldable VADs using mechanical and/or material means. Me-chanically folded structures adapt joints and links to facilitate the folding process whilst utilization of elastic materials al-lows the structure to be bent or twisted without permanent deformation. Current and future developments of foldable VADs are discussed. Foldable pumps could generate less blood damage and mechanical wear as compared to current miniature percutaneous VADs. Therefore, foldable VADs have the potential for longer-term application and minimally invasive insertion, providing a promising solution for heart failure patients.","PeriodicalId":89473,"journal":{"name":"Recent patents on biomedical engineering","volume":"50 1","pages":"208-222"},"PeriodicalIF":0.0,"publicationDate":"2012-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82250160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Recent Advances in Transcatheter Heart Valve Replacement: A Review on Aortic and Mitral Implantation 经导管心脏瓣膜置换术的最新进展:主动脉瓣和二尖瓣置换术的研究进展
Recent patents on biomedical engineering Pub Date : 2012-11-30 DOI: 10.2174/1874764711205030235
Munirah Ismail, J. Hon, Zhi Wei Chan, H. Leo
{"title":"Recent Advances in Transcatheter Heart Valve Replacement: A Review on Aortic and Mitral Implantation","authors":"Munirah Ismail, J. Hon, Zhi Wei Chan, H. Leo","doi":"10.2174/1874764711205030235","DOIUrl":"https://doi.org/10.2174/1874764711205030235","url":null,"abstract":"","PeriodicalId":89473,"journal":{"name":"Recent patents on biomedical engineering","volume":"45 1","pages":"235-252"},"PeriodicalIF":0.0,"publicationDate":"2012-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82437517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Transcatheter Aortic Valve Technology: Current State 经导管主动脉瓣技术:现状
Recent patents on biomedical engineering Pub Date : 2012-07-31 DOI: 10.2174/1874764711205020114
E. Young, K. Fukamachi
{"title":"Transcatheter Aortic Valve Technology: Current State","authors":"E. Young, K. Fukamachi","doi":"10.2174/1874764711205020114","DOIUrl":"https://doi.org/10.2174/1874764711205020114","url":null,"abstract":"","PeriodicalId":89473,"journal":{"name":"Recent patents on biomedical engineering","volume":"71 1","pages":"114-121"},"PeriodicalIF":0.0,"publicationDate":"2012-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77287692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patents and the development on polymer based nanomaterial (PAMAM dendrimer) for biomedical applications 生物医学应用的高分子基纳米材料(PAMAM树突状聚合物)的专利和发展
Recent patents on biomedical engineering Pub Date : 2012-07-31 DOI: 10.2174/1874764711205020159
D. Rajasekhar, P. Liao
{"title":"Patents and the development on polymer based nanomaterial (PAMAM dendrimer) for biomedical applications","authors":"D. Rajasekhar, P. Liao","doi":"10.2174/1874764711205020159","DOIUrl":"https://doi.org/10.2174/1874764711205020159","url":null,"abstract":"","PeriodicalId":89473,"journal":{"name":"Recent patents on biomedical engineering","volume":"35 1","pages":"159-174"},"PeriodicalIF":0.0,"publicationDate":"2012-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88807712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Review on Digital Breast Tomosynthesis Patents 数字化乳腺断层合成专利综述
Recent patents on biomedical engineering Pub Date : 2012-07-01 DOI: 10.2174/1874764711205020175
Joao Matos Monteiro, A. Ribeiro, L. Lacerda
{"title":"Review on Digital Breast Tomosynthesis Patents","authors":"Joao Matos Monteiro, A. Ribeiro, L. Lacerda","doi":"10.2174/1874764711205020175","DOIUrl":"https://doi.org/10.2174/1874764711205020175","url":null,"abstract":"","PeriodicalId":89473,"journal":{"name":"Recent patents on biomedical engineering","volume":"42 1 1","pages":"175-182"},"PeriodicalIF":0.0,"publicationDate":"2012-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91026155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Recent Patents on Emerging Therapeutics for the Treatment of Glaucoma, Age Related Macular Degeneration and Uveitis. 治疗青光眼、老年性黄斑变性和葡萄膜炎的新专利。
Recent patents on biomedical engineering Pub Date : 2012-04-01 DOI: 10.2174/1874764711205010083
Aswani Dutt Vadlapudi, Ashaben Patel, Kishore Cholkar, Ashim K Mitra
{"title":"Recent Patents on Emerging Therapeutics for the Treatment of Glaucoma, Age Related Macular Degeneration and Uveitis.","authors":"Aswani Dutt Vadlapudi, Ashaben Patel, Kishore Cholkar, Ashim K Mitra","doi":"10.2174/1874764711205010083","DOIUrl":"10.2174/1874764711205010083","url":null,"abstract":"<p><p>Advancements in the field and rising interest among pharmaceutical researchers have led to the development of new molecules with enhanced therapeutic activity. Design of new drugs which can target a particular pathway and/or explore novel targets is of immense interest to ocular pharmacologists worldwide. Delivery of suitable pharmacologically active agents at proper dose (within the therapeutic window) to the target tissues without any toxicity to the healthy ocular tissues still remain an elusive task. Moreover, the presence of static and dynamic barriers to drug absorption including the corneal epithelium (lipophilic), corneal and scleral stroma (hydrophilic), conjunctival lymphatics, choroidal vasculature and the blood-ocular barriers also pose a significant challenge for achieving therapeutic drug concentrations at the target site. Although many agents are currently available, new compounds are being introduced for treating various ocular diseases. Deeper understanding of the etiology and complex mechanisms associated with the disease condition would aid in the development of potential therapeutic candidates. Novel small molecules as well as complex biotechnology derived macromolecules with superior efficacy, safety and tolerability are being developed. Therefore, this review article provides an overview of existing drugs, treatment options, advances in emerging therapeutics and related recent patents for the treatment of ocular disorders such as glaucoma, age related macular degeneration (AMD) and uveitis.</p>","PeriodicalId":89473,"journal":{"name":"Recent patents on biomedical engineering","volume":"5 1","pages":"83-101"},"PeriodicalIF":0.0,"publicationDate":"2012-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2174/1874764711205010083","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32828647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 25
Nanobiotechnology and nanostructured therapeutic delivery systems 纳米生物技术和纳米结构治疗递送系统
Recent patents on biomedical engineering Pub Date : 2012-03-31 DOI: 10.2174/1874764711205010029
Nathan J. Castro, Jose Umanzor-Alvarez, Lijie Grace Zhang, M. Keidar
{"title":"Nanobiotechnology and nanostructured therapeutic delivery systems","authors":"Nathan J. Castro, Jose Umanzor-Alvarez, Lijie Grace Zhang, M. Keidar","doi":"10.2174/1874764711205010029","DOIUrl":"https://doi.org/10.2174/1874764711205010029","url":null,"abstract":"Pharmaceutical development and therapeutic delivery as they pertain to nanomedicine predominantly involve the use of nanometer-sized (1-100nm) structures or complexes comprised of two or more constituents whose goal is to deliver a specific therapeutic to a targeted site for localized treatment. This illustrates one of the predominant underlying paradigms in nanomedicine: increased efficacy through targeted therapeutic delivery. With the advent of nanobiotechnology the precisely targeted delivery of pharmaceuticals and therapeutic agents can be achieved through a myriad of approaches which can be delineated by the level of bio-activity beginning with the nano-scale dispersion of pharmaceuticals. The primary constituent of nano-scale medicinal complexes is the pharmaceutical itself with the other contributing as a uni-functional \"vehicle\" for transport; a bi-functional natural or synthetic biodegradable vesicle or \"shell\" for encapsulation and timed release; or multi-functional components which include surface modification of said vesicle/shells for target-specific binding and/or conjugated with a contrast or fluorescent agent for imaging and/or tracking of drug mobility. This review will focus on cutting-edge nanostructured drug delivery systems for various biomedical applications. In addition, nanobiotechnology and its role in mediating tissue regeneration will be introduced. Recent awarded patents and their role in nanotechnology and nanomedicine development will be discussed.","PeriodicalId":89473,"journal":{"name":"Recent patents on biomedical engineering","volume":"13 1","pages":"29-40"},"PeriodicalIF":0.0,"publicationDate":"2012-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82062998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Recent Advances in Liposome Techniques and their Applications in Arthritis 脂质体技术及其在关节炎中的应用进展
Recent patents on biomedical engineering Pub Date : 2012-03-31 DOI: 10.2174/1874764711205010057
Sang-Hyug Park, Aman Seth, Sangmin Lee, B. Min, Song-Ja Kim, T. Song, K. Hasty, Hongsik Cho
{"title":"Recent Advances in Liposome Techniques and their Applications in Arthritis","authors":"Sang-Hyug Park, Aman Seth, Sangmin Lee, B. Min, Song-Ja Kim, T. Song, K. Hasty, Hongsik Cho","doi":"10.2174/1874764711205010057","DOIUrl":"https://doi.org/10.2174/1874764711205010057","url":null,"abstract":"","PeriodicalId":89473,"journal":{"name":"Recent patents on biomedical engineering","volume":"150 1","pages":"57-62"},"PeriodicalIF":0.0,"publicationDate":"2012-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75149632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Recent Advancements in Ligament Replacement 韧带置换术的最新进展
Recent patents on biomedical engineering Pub Date : 2011-11-30 DOI: 10.2174/1874764711104030196
E. Ekwueme, A. Kwansa, Kevin Sharif, S. El-Amin, J. Freeman
{"title":"Recent Advancements in Ligament Replacement","authors":"E. Ekwueme, A. Kwansa, Kevin Sharif, S. El-Amin, J. Freeman","doi":"10.2174/1874764711104030196","DOIUrl":"https://doi.org/10.2174/1874764711104030196","url":null,"abstract":"The anterior cruciate ligament (ACL) is important for knee stability and kinematics. It is also the most com- monly injured ligament of the knee and due to its poor healing potential, severe damage warrants surgical intervention in- cluding complete replacement. Therefore, investigators have begun to pursue new techniques and devices for the repair, regeneration, and replacement of the ACL. These options involve the use of mechanically functional grafts that are designed to increase implant stability in order to withstand normal mechanical loads (while promoting ligament develop- ment in some cases). This article presents background on the ACL and its replacement, novel replacement approaches utilizing a variety of materials, and recent patent coverage.","PeriodicalId":89473,"journal":{"name":"Recent patents on biomedical engineering","volume":"1 1","pages":"196-204"},"PeriodicalIF":0.0,"publicationDate":"2011-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88224024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
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