Journal of biological physics and chemistry : JBPC最新文献

{"title":"Great medical discoveries of the 21st century Part II: Establishment of the gravitational evolutionary law in the vertebrates","authors":"K. Nishihara","doi":"10.4024/08ni7r.jbpc.17.03","DOIUrl":"https://doi.org/10.4024/08ni7r.jbpc.17.03","url":null,"abstract":"","PeriodicalId":88911,"journal":{"name":"Journal of biological physics and chemistry : JBPC","volume":"17 1","pages":"94-124"},"PeriodicalIF":0.0,"publicationDate":"2017-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41707505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A tragic fire in Kensington, London","authors":"J. Ramsden","doi":"10.4024/07RA17E.JBPC.17.02","DOIUrl":"https://doi.org/10.4024/07RA17E.JBPC.17.02","url":null,"abstract":"","PeriodicalId":88911,"journal":{"name":"Journal of biological physics and chemistry : JBPC","volume":"17 1","pages":"43-46"},"PeriodicalIF":0.0,"publicationDate":"2017-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47848664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can glyphosate’s disruption of the gut microbiome and induction of sulfate deficiency explain the epidemic in gout and associated diseases in the industrialized world?","authors":"S. Seneff, N. Causton, G. Nigh, G. Koenig, D. Avalon","doi":"10.4024/04SE17A.JBPC.17.02","DOIUrl":"https://doi.org/10.4024/04SE17A.JBPC.17.02","url":null,"abstract":"Gout is an ancient disease, which has been known at least since Babylonian times. The word “gout” is derived from the Latin word “gutta” (drop); it signifies the belief that a poison, seeping into the joint drop by drop, is the cause [1]. Much is understood about the aetiology of gout, although there are also still many mysteries yet to be resolved. Gout is an inflammatory joint disease that is typically episodic and localized to certain joints, especially the metatarsophalangeal (MTP)1 joint and other joints in feet and fingers. An acute episode of gout is usually triggered by urate crystals in the joint, which induce a cascade reaction beginning with the influx of immune cells, especially neutrophils, which release cytokines such as IL-1β and IL-6, causing an inflammatory response leading to oxidative damage and intense pain, and terminating when feedback responses finally dampen the signal. While gout is associated with high serum urate, the association is not as strong as would be expected. Many people with elevated serum urate never experience gout, and many gout sufferers have normal levels of serum urate [2]. Thus, it is generally agreed that something else","PeriodicalId":88911,"journal":{"name":"Journal of biological physics and chemistry : JBPC","volume":"17 1","pages":"53-76"},"PeriodicalIF":0.0,"publicationDate":"2017-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45072824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Children with epilepsy and autistic spectrum disorders show similarly high levels of urinary p-cresol","authors":"G. Tevzadze, L. Shanshiashvilli, D. Mikeladze","doi":"10.4024/05TE17A.JBPC.17.02","DOIUrl":"https://doi.org/10.4024/05TE17A.JBPC.17.02","url":null,"abstract":"","PeriodicalId":88911,"journal":{"name":"Journal of biological physics and chemistry : JBPC","volume":"17 1","pages":"77-80"},"PeriodicalIF":0.0,"publicationDate":"2017-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43728889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can bacteria develop resistance to photocatalytically generated reactive oxygen species","authors":"J. Ramsden","doi":"10.4024/06RA17N.JBPC.17.02","DOIUrl":"https://doi.org/10.4024/06RA17N.JBPC.17.02","url":null,"abstract":"","PeriodicalId":88911,"journal":{"name":"Journal of biological physics and chemistry : JBPC","volume":"17 1","pages":"47-51"},"PeriodicalIF":0.0,"publicationDate":"2017-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42532426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Suggestions for reducing the fraud problem","authors":"W. Courtney","doi":"10.4024/03CO17F.jbpc.17.02","DOIUrl":"https://doi.org/10.4024/03CO17F.jbpc.17.02","url":null,"abstract":"","PeriodicalId":88911,"journal":{"name":"Journal of biological physics and chemistry : JBPC","volume":"17 1","pages":"81-88"},"PeriodicalIF":0.0,"publicationDate":"2017-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47409753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assaults on health","authors":"J. Ramsden","doi":"10.4024/02RA17E.JBPC.17.01","DOIUrl":"https://doi.org/10.4024/02RA17E.JBPC.17.01","url":null,"abstract":"","PeriodicalId":88911,"journal":{"name":"Journal of biological physics and chemistry : JBPC","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41487662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Funding science: A new law, new arrangements","authors":"G. Evans","doi":"10.4024/01ev17f.jbpc.17.01","DOIUrl":"https://doi.org/10.4024/01ev17f.jbpc.17.01","url":null,"abstract":"","PeriodicalId":88911,"journal":{"name":"Journal of biological physics and chemistry : JBPC","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46325172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Glyphosate pathways to modern diseases VI: Prions, amyloidoses and autoimmune neurological diseases","authors":"Anthony Samsel, S. Seneff","doi":"10.4024/25SA16A.JBPC.17.01","DOIUrl":"https://doi.org/10.4024/25SA16A.JBPC.17.01","url":null,"abstract":"At first glance, multiple sclerosis (MS) and autism appear to have little in common, aside from the fact that both are neurological diseases. Autism is a condition with prenatal or early childhood onset, characterized by repetitive behaviours, impaired social interaction and cognitive impairment. The male:female ratio for autism is 4:1, while multiple sclerosis is twice as common in women as in men; its first symptoms usually begin in early adulthood to involve impaired lower limb mobility, although in later stages it affects both mental and physical capabilities. Both conditions are, however, associated with inflammatory autoimmune features [1, 2], and both diseases are viewed as having an environmental and a genetic component [3–6]. A study comparing a population of 658 MS patients with the general population found an association between MS and increased rates of asthma, inflammatory bowel disease (IBD), type 1 diabetes mellitus, pernicious anaemia and autoimmune thyroid disease [7], all of which have also been linked to autism [8–11]. These conditions are all considered to be autoimmune diseases, which can be triggered through molecular mimicry, where an antibody responding to a foreign protein that resembles a native protein becomes sensitized to the native protein as well [12]. A paper by Shoenfeld and Aron-Maor in 2000 developed the argument that both autism and MS may be examples of an autoimmune reaction via mimicry following exposure to an antigenic stimulus, possibly from an infection or through vaccination [13]. They further propose specifically that myelin basic protein (MBP) and other proteins constituting the myelin sheath are attacked by the immune system in both autism and MS. This has been recognized by many others in autism [14, 15] and MS [16–20]. In 1982, Weizman et al. reported a cell-mediated autoimmune response to human MBP in 76% of the autistic children studied [16]. Immune sensitization to the myelin sheath proteins could arise either through mimicry as a consequence of exposure of the immune system to a foreign antigen with a similar peptide sequence that is * Corresponding author. E-mail: seneff@csail.mit.edu Glyphosate pathways to modern diseases VI: Prions, amyloidoses and autoimmune neurological diseases Anthony Samsel1 and Stephanie Seneff 2, * 1 Samsel Environmental and Public Health Services, Deerfield, NH 03037, USA 2 Computer Science and Artificial Intelligence Laboratory, MIT, Cambridge, MA 02139, USA","PeriodicalId":88911,"journal":{"name":"Journal of biological physics and chemistry : JBPC","volume":"17 1","pages":"8-32"},"PeriodicalIF":0.0,"publicationDate":"2017-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42827022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Calculation of tautomeric equilibrium constants in complementary DNA pairs","authors":"Z. Pachulia, J. Kereselidze","doi":"10.4024/20PA16A.jbpc.16.04","DOIUrl":"https://doi.org/10.4024/20PA16A.jbpc.16.04","url":null,"abstract":"","PeriodicalId":88911,"journal":{"name":"Journal of biological physics and chemistry : JBPC","volume":"16 1","pages":"177-180"},"PeriodicalIF":0.0,"publicationDate":"2016-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70607383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}