The open spectroscopy journal最新文献_第3页

NMR Studies of Complexes of Fluorides of Triethylamine 三乙胺氟化物配合物的核磁共振研究

The open spectroscopy journal Pub Date : 2011-11-30 DOI: 10.2174/1874383801105010026

N. Ilayaraja, S. Krishnan, G. Ravindran, N. Renganathan

引用次数: 1

Spectroscopic Evaluation of the Atomic Size 原子尺寸的光谱学评价

The open spectroscopy journal Pub Date : 2011-05-20 DOI: 10.2174/1874383801105010013

N. Islam

{"title":"Spectroscopic Evaluation of the Atomic Size","authors":"N. Islam","doi":"10.2174/1874383801105010013","DOIUrl":"https://doi.org/10.2174/1874383801105010013","url":null,"abstract":"A new algorithm for evaluating the atomic size is suggested by entailing the atomic spectroscopic data-the wave number. The basic tenet of the present method is (i) to convert a multi-electron atom system to a hydrogenic atom to invoke the Bohr model for the mechanism of electron transition, and (ii) to use the experimental atomic spectroscopic data of multi electron systems to determine the atomic radii. The estimated set of size data appears to satisfy the entire 'sine qua non' of sizes of atoms of the periodic table. Relativistic effect appears to have been significantly included in the suggested algorithm for evaluating the atomic radii. The express periodicity of periods and groups of periodic table exhibited by the computed atomic radii, d and f block contraction and the manifestation of the relativistic effect in the sizes of lanthanoids and actinoids etc speak volume of the efficacy of the present method in computing atomic size. Furthermore, as a validity test, the size data evaluated in the present work have been exploited to calculate some physical descriptors of the real world like equilibrium inter nuclear distances of a good number of hetero nuclear diatomics. We have noted the surprisingly close agreement between the theoretical and the experimental equilibrium inter-nuclear distances.","PeriodicalId":88758,"journal":{"name":"The open spectroscopy journal","volume":"5 1","pages":"13-25"},"PeriodicalIF":0.0,"publicationDate":"2011-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68070709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Substituent Effects of Porphyrin on Singlet Oxygen Generation Quantum Yields 卟啉取代基对单线态产氧量子产率的影响

The open spectroscopy journal Pub Date : 2011-03-01 DOI: 10.2174/1874383801105010001

Fotis Nifiatis

引用次数: 50

Effect of Physical and Chemical Treatments on the Electrical and Structural Properties of Water Hyacinth~!2010-05-18~!2010-07-26~!2010-09-03~! 理化处理对水葫芦电学和结构性能的影响2010-05-18 2010-07-26 2010-09-03

The open spectroscopy journal Pub Date : 2010-09-03 DOI: 10.2174/1874383801004010032

M. Ibrahim

引用次数: 8

Cross-Fitting of Residual Dipolar Couplings 剩余偶极耦合的交叉拟合

The open spectroscopy journal Pub Date : 2010-04-22 DOI: 10.2174/1874383801004010016

G. Kummerlöwe, S. Schmitt, B. Luy

引用次数: 30

Mechanism of Pollution Control for Aquatic Plant Water Hyacinth 水生植物水葫芦污染控制机理研究

The open spectroscopy journal Pub Date : 2010-04-09 DOI: 10.2174/1874383801004010010

M. Ibrahim, .. Z.I.A.AL-Fifi

引用次数: 15

Improved 1.5 T Magnetic Resonance Spectroscopy in the Human Calf with a Spatially Selective Radio Frequency Surface Coil 利用空间选择性射频表面线圈改进的人小腿1.5 T磁共振波谱

The open spectroscopy journal Pub Date : 2010-01-13 DOI: 10.2174/1874383801004010001

M. Alfonsetti, C. Testa, S. Iotti, E. Malucelli, V. Clementi, B. Barbiroli, G. Placidi, A. Sotgiu, M. Alecci

{"title":"Improved 1.5 T Magnetic Resonance Spectroscopy in the Human Calf with a Spatially Selective Radio Frequency Surface Coil","authors":"M. Alfonsetti, C. Testa, S. Iotti, E. Malucelli, V. Clementi, B. Barbiroli, G. Placidi, A. Sotgiu, M. Alecci","doi":"10.2174/1874383801004010001","DOIUrl":"https://doi.org/10.2174/1874383801004010001","url":null,"abstract":"We describe the use of a transverse field RF surface coil that improves 1.5 T proton MR spectroscopy in the human calf. A 2-element figure-of-eight (FO8) transverse field RF surface coil (diameter 2R=10 cm; separation between the two linear current elements 2s=1cm) and a circular loop (CL) coil of equal diameter where built and tested with proton PRESS spectra at 1.5 T. The 1 H PRESS spectra obtained in the resting calf muscle of healthy volunteers showed that the FO8 coil allows a higher PRESS SNR (up to a factor 4.5) within a region of about 20 mm centred at about 12 mm from the coil plane, as compared to a standard CL coil. We found also a faster PRESS SNR decrease in the muscle tissue for anterior/posterior distance >20 mm using the FO8 coil. The measured PRESS SNR in the fat tissues of the calf showed a signal mostly localised within 10 mm from the coils surface and with an improved SNR (up to 5.5 times) observed in the presence of the FO8 coil as compared to the CL coil of equal diameter. The FO8 coil design can be advantageous for MRS applications, since it allows higher SNR from a small VOI positioned centrally within a relatively narrow region at a given depth in the human calf. The reported spatial SNR features of the FO8 coil design should also be useful for 1 H and 31 P MRS metabolites quantification in the human brain.","PeriodicalId":88758,"journal":{"name":"The open spectroscopy journal","volume":"4 1","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2010-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68070585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Structural Studies of the Complex Between Akt-in and the Akt2-PH Domain Suggest that the Peptide Acts as an Allosteric Inhibitor of the Akt Kinase Akt-in和Akt2-PH结构域复合物的结构研究表明，该肽可作为Akt激酶的变构抑制剂

The open spectroscopy journal Pub Date : 2009-09-10 DOI: 10.2174/1874383800903010065

V. Ropars, P. Barthe, Chihao Wang, Wenlung Chen, D. Tzou, Anne Descours, Loïc Martin, M. Noguchi, D. Auguin, C. Roumestand

{"title":"Structural Studies of the Complex Between Akt-in and the Akt2-PH Domain Suggest that the Peptide Acts as an Allosteric Inhibitor of the Akt Kinase","authors":"V. Ropars, P. Barthe, Chihao Wang, Wenlung Chen, D. Tzou, Anne Descours, Loïc Martin, M. Noguchi, D. Auguin, C. Roumestand","doi":"10.2174/1874383800903010065","DOIUrl":"https://doi.org/10.2174/1874383800903010065","url":null,"abstract":"Serine/threonine kinase Akt plays a central role in the regulation of cell survival and proliferation. Hence, the search for Akt specific inhibitors constitutes an attractive strategy for anticancer therapy. We have previously demonstrated that the proto-oncogene TCL1 coactivates Akt upon binding to its Plekstrin Homology Domain, and we proposed a model for the structure of the complex TCL1:Akt2-PHD. This model led to the rational design of Akt-in, a peptide inhibitor spanning the A s-strand of human TCL1 that binds Akt2 PH domain and inhibits the kinase activation. In the present report, we used NMR spectroscopy to determine the 3D structure of the peptide free in solution and bound to Akt2-PHD. NMR chemical shift mapping was used to determine the imprint of Akt-in on the PH domain; whereas peptide Ala-scanning revealed which peptide residues were involved in the interaction. Together with the solution structure of Akt2-PHD, these results allowed us to dock Akt-in on the PH domain. The docked complex suggests that while Akt-in binds Akt2-PHD in a region overlapping the binding site of TCL1, its mode of interaction is markedly different. Moreover, the affinity was disappointingly low, contrary to that published previously. Besides providing a description of the interaction between Akt-in an Akt2 PH domain, the present work brings additional clues on the putative peptide mode of action. Instead of behaving as an analog of PtdIns, as previously suggested, Akt-in might act as an \"allosteric\" inhibitor, maintaining the full-length kinase in its \"closed\" inactive conformation, rather than disturbing the membrane anchorage of its \"open\" active conformation.","PeriodicalId":88758,"journal":{"name":"The open spectroscopy journal","volume":"3 1","pages":"65-76"},"PeriodicalIF":0.0,"publicationDate":"2009-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68070546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Surface Wave Discharges Generated with Ar/He and Ar/N2 Gas Mixturesat Atmospheric Pressure 常压下Ar/He和Ar/N2混合气体产生的表面波放电

The open spectroscopy journal Pub Date : 2009-04-24 DOI: 10.2174/1874383800903010052

J. Muñoz, J. Bravo, M. Calzada

引用次数: 7

Temperature-Dependent Excited State Absorption in DNA and LNA Oligomers Supports an Emerging Model of Excited State Dynamics in DNA DNA和LNA低聚物中温度依赖的激发态吸收支持DNA激发态动力学的新兴模型

The open spectroscopy journal Pub Date : 2009-03-18 DOI: 10.2174/1874383800903010043

S. Konorov, H. G. Schulze, C. Addison, C. Haynes, R. Turner, M. Blades

{"title":"Temperature-Dependent Excited State Absorption in DNA and LNA Oligomers Supports an Emerging Model of Excited State Dynamics in DNA","authors":"S. Konorov, H. G. Schulze, C. Addison, C. Haynes, R. Turner, M. Blades","doi":"10.2174/1874383800903010043","DOIUrl":"https://doi.org/10.2174/1874383800903010043","url":null,"abstract":"Transient absorption measurements of excited states in DNA and LNA were performed using a femtosecond pump-probe arrangement with excitation at 266 nm and absorption monitored at 400 nm while varying the sample tem- perature between 5 °C and 70 °C. Samples consisted of adenine monophosphate monomer, polyadenine 12-mer in single- stranded form, and polyadenine 12-mer in hybridized form. Excited states decayed in a biphasic manner with short-lived (￻ 1) and long-lived (￻ 2) components, while the monomer had only a 'single' short-lived decay time. Temperature increases increased absorption intensities and reduced ￻ 1 until they approached those of the monomer at high temperatures (where stacking is minimal). These results suggest that the initial excitation in stacked regions is cooperative and involves several bases and that the number of bases involved is reduced with increasing temperature. In contrast, increasing temperatures had little effect on ￻ 2 while absorption intensities decreased, suggesting that very few, perhaps only two, stacked bases are involved and that their number is reduced at higher temperatures. We found no clear evidence of melting point transitions indicating that those excited states probed with our arrangement were not dependent on base pairing. Our results are con- sistent with and strengthen an emerging consensus model of excited state dynamics in DNA wherein a UV photon is ab- sorbed collectively by electronically coupled and thus well-stacked intrachain bases. This collective excitation results in a Frenkel exciton that is delocalized over these bases, and the Frenkel exciton then decays rapidly to a long-lived, lower en- ergy, dark intrachain exciplex.","PeriodicalId":88758,"journal":{"name":"The open spectroscopy journal","volume":"3 1","pages":"43-51"},"PeriodicalIF":0.0,"publicationDate":"2009-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68069478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4