Vinod C Kaggal, Ravikumar Komandur Elayavilli, Saeed Mehrabi, Joshua J Pankratz, Sunghwan Sohn, Yanshan Wang, Dingcheng Li, Majid Mojarad Rastegar, Sean P Murphy, Jason L Ross, Rajeev Chaudhry, James D Buntrock, Hongfang Liu
{"title":"Toward a Learning Health-care System - Knowledge Delivery at the Point of Care Empowered by Big Data and NLP.","authors":"Vinod C Kaggal, Ravikumar Komandur Elayavilli, Saeed Mehrabi, Joshua J Pankratz, Sunghwan Sohn, Yanshan Wang, Dingcheng Li, Majid Mojarad Rastegar, Sean P Murphy, Jason L Ross, Rajeev Chaudhry, James D Buntrock, Hongfang Liu","doi":"10.4137/BII.S37977","DOIUrl":"https://doi.org/10.4137/BII.S37977","url":null,"abstract":"<p><p>The concept of optimizing health care by understanding and generating knowledge from previous evidence, ie, the Learning Health-care System (LHS), has gained momentum and now has national prominence. Meanwhile, the rapid adoption of electronic health records (EHRs) enables the data collection required to form the basis for facilitating LHS. A prerequisite for using EHR data within the LHS is an infrastructure that enables access to EHR data longitudinally for health-care analytics and real time for knowledge delivery. Additionally, significant clinical information is embedded in the free text, making natural language processing (NLP) an essential component in implementing an LHS. Herein, we share our institutional implementation of a big data-empowered clinical NLP infrastructure, which not only enables health-care analytics but also has real-time NLP processing capability. The infrastructure has been utilized for multiple institutional projects including the MayoExpertAdvisor, an individualized care recommendation solution for clinical care. We compared the advantages of big data over two other environments. Big data infrastructure significantly outperformed other infrastructure in terms of computing speed, demonstrating its value in making the LHS a possibility in the near future. </p>","PeriodicalId":88397,"journal":{"name":"Biomedical informatics insights","volume":"8 Suppl 1","pages":"13-22"},"PeriodicalIF":0.0,"publicationDate":"2016-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4137/BII.S37977","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34644173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Manabu Torii, Sameer S Tilak, Son Doan, Daniel S Zisook, Jung-Wei Fan
{"title":"Mining Health-Related Issues in Consumer Product Reviews by Using Scalable Text Analytics.","authors":"Manabu Torii, Sameer S Tilak, Son Doan, Daniel S Zisook, Jung-Wei Fan","doi":"10.4137/BII.S37791","DOIUrl":"https://doi.org/10.4137/BII.S37791","url":null,"abstract":"<p><p>In an era when most of our life activities are digitized and recorded, opportunities abound to gain insights about population health. Online product reviews present a unique data source that is currently underexplored. Health-related information, although scarce, can be systematically mined in online product reviews. Leveraging natural language processing and machine learning tools, we were able to mine 1.3 million grocery product reviews for health-related information. The objectives of the study were as follows: (1) conduct quantitative and qualitative analysis on the types of health issues found in consumer product reviews; (2) develop a machine learning classifier to detect reviews that contain health-related issues; and (3) gain insights about the task characteristics and challenges for text analytics to guide future research. </p>","PeriodicalId":88397,"journal":{"name":"Biomedical informatics insights","volume":"8 Suppl 1","pages":"1-11"},"PeriodicalIF":0.0,"publicationDate":"2016-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4137/BII.S37791","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34698134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mobile Health (mHealth) Services and Online Health Educators.","authors":"Muhammad Anshari, Mohammad Nabil Almunawar","doi":"10.4137/BII.S35388","DOIUrl":"https://doi.org/10.4137/BII.S35388","url":null,"abstract":"<p><p>Mobile technology enables health-care organizations to extend health-care services by providing a suitable environment to achieve mobile health (mHealth) goals, making some health-care services accessible anywhere and anytime. Introducing mHealth could change the business processes in delivering services to patients. mHealth could empower patients as it becomes necessary for them to become involved in the health-care processes related to them. This includes the ability for patients to manage their personal information and interact with health-care staff as well as among patients themselves. The study proposes a new position to supervise mHealth services: the online health educator (OHE). The OHE should be occupied by special health-care staffs who are trained in managing online services. A survey was conducted in Brunei and Indonesia to discover the roles of OHE in managing mHealth services, followed by a focus group discussion with participants who interacted with OHE in a real online health scenario. Data analysis showed that OHE could improve patients' confidence and satisfaction in health-care services. </p>","PeriodicalId":88397,"journal":{"name":"Biomedical informatics insights","volume":"8 ","pages":"19-27"},"PeriodicalIF":0.0,"publicationDate":"2016-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4137/BII.S35388","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34446488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Tennessee’s 3-Star Report: Using Available Data Systems to Reduce Missed Opportunities to Vaccinate Preteens","authors":"Kelly L. Moore, Melissa K. Fankhauser, P. Hull","doi":"10.4137/BII.S40207","DOIUrl":"https://doi.org/10.4137/BII.S40207","url":null,"abstract":"All preteens should receive tetanus–diphtheria–pertussis vaccine (Tdap), quadrivalent meningococcal vaccine (Men-ACWY), and the human papillomavirus (HPV) cancer vaccine series. In Tennessee, HPV vaccination rates have stagnated at low levels for a decade. Three fundamental strategies to reduce missed opportunities for immunization include administering all recommended vaccines at the same visit, making strong recommendations for vaccines, and auditing and feedback. In Tennessee, during each summer, a surge of preteens visit local health departments (LHDs) to receive a required Tdap vaccine before entering seventh grade, presenting an opportunity to administer Men-ACWY and HPV. The Tennessee Immunization Program (TIP) coined the term “3-Star visit” for such encounters and developed a monthly report to track them using data from the Patient Tracking Billing Management Information System (PTBMIS) used by LHDs across Tennessee. Implementation of this quality improvement report has correlated with a substantial increase in 3-Star visits from 2013 to 2016, particularly during the summer months.","PeriodicalId":88397,"journal":{"name":"Biomedical informatics insights","volume":"8 1","pages":"15 - 21"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4137/BII.S40207","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70687420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Some correlates of electronic health information management system success in nigerian teaching hospitals.","authors":"Adebowale I Ojo, Sunday O Popoola","doi":"10.4137/BII.S20229","DOIUrl":"https://doi.org/10.4137/BII.S20229","url":null,"abstract":"<p><p>Nowadays, an electronic health information management system (EHIMS) is crucial for patient care in hospitals. This paper explores the aspects and elements that contribute to the success of EHIMS in Nigerian teaching hospitals. The study adopted a survey research design. The population of study comprised 442 health information management personnel in five teaching hospitals that had implemented EHIMS in Nigeria. A self-developed questionnaire was used as an instrument for data collection. The findings revealed that there is a positive, close relationship between all the identified factors and EHIMS's success: technical factors (r = 0.564, P < 0.05); social factors (r = 0.616, P < 0.05); organizational factors (r = 0.621, P < 0.05); financial factors (r = 0.705, P < 0.05); and political factors (r = 0.589, P < 0.05). We conclude that consideration of all the identified factors was highly significant for the success of EHIMS in Nigerian teaching hospitals. </p>","PeriodicalId":88397,"journal":{"name":"Biomedical informatics insights","volume":"7 ","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2015-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4137/BII.S20229","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33311856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pierre Zweigenbaum, Thomas Lavergne, Natalia Grabar, Thierry Hamon, Sophie Rosset, Cyril Grouin
{"title":"Combining an expert-based medical entity recognizer to a machine-learning system: methods and a case study.","authors":"Pierre Zweigenbaum, Thomas Lavergne, Natalia Grabar, Thierry Hamon, Sophie Rosset, Cyril Grouin","doi":"10.4137/BII.S11770","DOIUrl":"https://doi.org/10.4137/BII.S11770","url":null,"abstract":"<p><p>Medical entity recognition is currently generally performed by data-driven methods based on supervised machine learning. Expert-based systems, where linguistic and domain expertise are directly provided to the system are often combined with data-driven systems. We present here a case study where an existing expert-based medical entity recognition system, Ogmios, is combined with a data-driven system, Caramba, based on a linear-chain Conditional Random Field (CRF) classifier. Our case study specifically highlights the risk of overfitting incurred by an expert-based system. We observe that it prevents the combination of the 2 systems from obtaining improvements in precision, recall, or F-measure, and analyze the underlying mechanisms through a post-hoc feature-level analysis. Wrapping the expert-based system alone as attributes input to a CRF classifier does boost its F-measure from 0.603 to 0.710, bringing it on par with the data-driven system. The generalization of this method remains to be further investigated. </p>","PeriodicalId":88397,"journal":{"name":"Biomedical informatics insights","volume":"6 Suppl 1","pages":"51-62"},"PeriodicalIF":0.0,"publicationDate":"2013-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4137/BII.S11770","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31747827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mindy K Ross, Ko-Wei Lin, Karen Truong, Abhishek Kumar, Mike Conway
{"title":"Text Categorization of Heart, Lung, and Blood Studies in the Database of Genotypes and Phenotypes (dbGaP) Utilizing n-grams and Metadata Features.","authors":"Mindy K Ross, Ko-Wei Lin, Karen Truong, Abhishek Kumar, Mike Conway","doi":"10.4137/BII.S11987","DOIUrl":"https://doi.org/10.4137/BII.S11987","url":null,"abstract":"<p><p>The database of Genotypes and Phenotypes (dbGaP) allows researchers to understand phenotypic contribution to genetic conditions, generate new hypotheses, confirm previous study results, and identify control populations. However, effective use of the database is hindered by suboptimal study retrieval. Our objective is to evaluate text classification techniques to improve study retrieval in the context of the dbGaP database. We utilized standard machine learning algorithms (naive Bayes, support vector machines, and the C4.5 decision tree) trained on dbGaP study text and incorporated n-gram features and study metadata to identify heart, lung, and blood studies. We used the χ(2) feature selection algorithm to identify features that contributed most to classification performance and experimented with dbGaP associated PubMed papers as a proxy for topicality. Classifier performance was favorable in comparison to keyword-based search results. It was determined that text categorization is a useful complement to document retrieval techniques in the dbGaP. </p>","PeriodicalId":88397,"journal":{"name":"Biomedical informatics insights","volume":"6 ","pages":"35-45"},"PeriodicalIF":0.0,"publicationDate":"2013-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4137/BII.S11987","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31641327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Using conversation topics for predicting therapy outcomes in schizophrenia.","authors":"Christine Howes, Matthew Purver, Rose McCabe","doi":"10.4137/BII.S11661","DOIUrl":"10.4137/BII.S11661","url":null,"abstract":"<p><p>Previous research shows that aspects of doctor-patient communication in therapy can predict patient symptoms, satisfaction and future adherence to treatment (a significant problem with conditions such as schizophrenia). However, automatic prediction has so far shown success only when based on low-level lexical features, and it is unclear how well these can generalize to new data, or whether their effectiveness is due to their capturing aspects of style, structure or content. Here, we examine the use of topic as a higher-level measure of content, more likely to generalize and to have more explanatory power. Investigations show that while topics predict some important factors such as patient satisfaction and ratings of therapy quality, they lack the full predictive power of lower-level features. For some factors, unsupervised methods produce models comparable to manual annotation. </p>","PeriodicalId":88397,"journal":{"name":"Biomedical informatics insights","volume":"6 Suppl 1","pages":"39-50"},"PeriodicalIF":0.0,"publicationDate":"2013-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740209/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31655624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sunghwan Sohn, Cheryl Clark, Scott R Halgrim, Sean P Murphy, Siddhartha R Jonnalagadda, Kavishwar B Wagholikar, Stephen T Wu, Christopher G Chute, Hongfang Liu
{"title":"Analysis of cross-institutional medication description patterns in clinical narratives.","authors":"Sunghwan Sohn, Cheryl Clark, Scott R Halgrim, Sean P Murphy, Siddhartha R Jonnalagadda, Kavishwar B Wagholikar, Stephen T Wu, Christopher G Chute, Hongfang Liu","doi":"10.4137/BII.S11634","DOIUrl":"https://doi.org/10.4137/BII.S11634","url":null,"abstract":"<p><p>A large amount of medication information resides in the unstructured text found in electronic medical records, which requires advanced techniques to be properly mined. In clinical notes, medication information follows certain semantic patterns (eg, medication, dosage, frequency, and mode). Some medication descriptions contain additional word(s) between medication attributes. Therefore, it is essential to understand the semantic patterns as well as the patterns of the context interspersed among them (ie, context patterns) to effectively extract comprehensive medication information. In this paper we examined both semantic and context patterns, and compared those found in Mayo Clinic and i2b2 challenge data. We found that some variations exist between the institutions but the dominant patterns are common. </p>","PeriodicalId":88397,"journal":{"name":"Biomedical informatics insights","volume":"6 Suppl 1","pages":"7-16"},"PeriodicalIF":0.0,"publicationDate":"2013-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4137/BII.S11634","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31574766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Towards Converting Clinical Phrases into SNOMED CT Expressions.","authors":"Rohit J Kate","doi":"10.4137/BII.S11645","DOIUrl":"https://doi.org/10.4137/BII.S11645","url":null,"abstract":"<p><p>Converting information contained in natural language clinical text into computer-amenable structured representations can automate many clinical applications. As a step towards that goal, we present a method which could help in converting novel clinical phrases into new expressions in SNOMED CT, a standard clinical terminology. Since expressions in SNOMED CT are written in terms of their relations with other SNOMED CT concepts, we formulate the important task of identifying relations between clinical phrases and SNOMED CT concepts. We present a machine learning approach for this task and using the dataset of existing SNOMED CT relations we show that it performs well. </p>","PeriodicalId":88397,"journal":{"name":"Biomedical informatics insights","volume":"6 Suppl 1","pages":"29-37"},"PeriodicalIF":0.0,"publicationDate":"2013-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4137/BII.S11645","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31574768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}