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PET Scanning in Breast Cancer: A Clinician’s Perspective PET扫描在乳腺癌中的应用:临床医生的观点
Seminars in breast disease Pub Date : 2006-12-01 Epub Date: 2008-09-25 DOI: 10.1053/j.sembd.2007.02.002
Peter Boasberg MD
{"title":"PET Scanning in Breast Cancer: A Clinician’s Perspective","authors":"Peter Boasberg MD","doi":"10.1053/j.sembd.2007.02.002","DOIUrl":"10.1053/j.sembd.2007.02.002","url":null,"abstract":"<div><p>Breast cancer is the most common cancer among women excluding nonmelanotic skin cancers, and is the second leading cause of cancer deaths in women. In 2005, it is estimated there will be over 200,000 women diagnosed with breast cancer and approximately 40,000 deaths from the disease. Although the incidence of breast cancer remains high, the rate of death from breast cancer has recently been estimated to have diminished by 25% to 38% through the contribution of screening mammography<span> and adjuvant therapy. Despite these advances, breast cancer continues to remain a major personal and public health issue. Oncologists are continually seeking tools to aid the treatment decisions for patients with breast cancer. At every stage of a patient’s disease, accurate information is required to assess the extent of disease, the pattern of spread, and the response to therapy. The purpose of this paper is to review the existing data regarding the potential role of fluorodeoxyglucose positron emission topography (FDG-PET) scanning in the mangement of breast cancer patients from a clinician’s viewpoint.</span></p></div>","PeriodicalId":87785,"journal":{"name":"Seminars in breast disease","volume":"9 4","pages":"Pages 127-130"},"PeriodicalIF":0.0,"publicationDate":"2006-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1053/j.sembd.2007.02.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57941109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Computer-Aided Detection in the Mammographic Detection of Breast Cancer: Where, Why, and How With Screen-Film, Computed Radiography, and Full-Field Digital Mammography 乳腺x线摄影检测中的计算机辅助检测:在哪里，为什么，以及如何使用屏幕胶片，计算机x线摄影和全视场数字乳房x线摄影
Seminars in breast disease Pub Date : 2006-09-01 Epub Date: 2008-09-25 DOI: 10.1053/j.sembd.2007.01.004
Rachel F. Brem MD
{"title":"Computer-Aided Detection in the Mammographic Detection of Breast Cancer: Where, Why, and How With Screen-Film, Computed Radiography, and Full-Field Digital Mammography","authors":"Rachel F. Brem MD","doi":"10.1053/j.sembd.2007.01.004","DOIUrl":"10.1053/j.sembd.2007.01.004","url":null,"abstract":"<div><p><span>Mammography remains the mainstay for screening for breast cancer. However, screen-film mammography (SFM) is an imperfect examination with 10% to 35% of breast cancers not mammographically visible. A recently developed and implemented approach to the improved diagnosis of breast cancer is computer-aided detection (CAD), where computer algorithms and neural networks are used to mark potential areas of abnormalities on the mammogram for the radiologist to evaluate and determine whether additional workup is indicated. CAD has been extensively studied retrospectively and prospectively and has demonstrated a 7% to 20% improvement in breast cancer detection. This manuscript will review the current literature of CAD, the principles of computer assessment of mammograms, and where the state of the art is going in this transitional time from SFM to full-field digital mammography (FFDM) as well as </span>computed radiography for mammography. CAD implemented with mammography has demonstrated improvements in breast cancer detection for SFM, computed radiography, and FFDM. This manuscript will review the state of the art of CAD for the detection of breast cancer.</p></div>","PeriodicalId":87785,"journal":{"name":"Seminars in breast disease","volume":"9 3","pages":"Pages 99-104"},"PeriodicalIF":0.0,"publicationDate":"2006-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1053/j.sembd.2007.01.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57939211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Full Field Digital Mammography: Initial Medical Legal Concerns 全领域数字乳房x光摄影:初步的医疗法律问题
Seminars in breast disease Pub Date : 2006-09-01 Epub Date: 2008-09-25 DOI: 10.1053/j.sembd.2007.01.006
R. James Brenner MD, JD
{"title":"Full Field Digital Mammography: Initial Medical Legal Concerns","authors":"R. James Brenner MD, JD","doi":"10.1053/j.sembd.2007.01.006","DOIUrl":"10.1053/j.sembd.2007.01.006","url":null,"abstract":"<div><p>The introduction of full-field digital mammography into clinical practice invites changing concepts of potential medical legal liability in a field already suffering from high medical malpractice exposure. These include the lack of uniform quality control measures and the ability to perform extensive postprocessing manipulations, with unknown legal consequences.</p></div>","PeriodicalId":87785,"journal":{"name":"Seminars in breast disease","volume":"9 3","pages":"Pages 119-123"},"PeriodicalIF":0.0,"publicationDate":"2006-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1053/j.sembd.2007.01.006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57940984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Clinical Trials in Full-Field Digital Mammography 全视场数字乳房x线摄影的临床试验
Seminars in breast disease Pub Date : 2006-09-01 Epub Date: 2008-09-25 DOI: 10.1053/j.sembd.2007.01.002
John Lewin MD
{"title":"Clinical Trials in Full-Field Digital Mammography","authors":"John Lewin MD","doi":"10.1053/j.sembd.2007.01.002","DOIUrl":"10.1053/j.sembd.2007.01.002","url":null,"abstract":"<div><p>Since the development of the first prototype over a decade ago, full-field digital mammography (FFDM) has been touted as a technically superior way to detect breast cancer compared with screen-film mammography (SFM). Proving technical superiority, however, is easy compared with proving clinical superiority. Whereas the former requires only measurements on phantom images, the latter requires clinical trials to measure the interaction of the technology with real patients and the technologists and radiologists taking care of them. Starting in 1997, four clinical screening trials comparing FFDM with SFM have been conducted. The results of the trials are mixed, but with the publication of the largest and most recent trial, conducted by the American College of Radiology Imaging Network, there are finally statistically significant results showing FFDM to be clinically superior to SFM for specific groups of women.</p></div>","PeriodicalId":87785,"journal":{"name":"Seminars in breast disease","volume":"9 3","pages":"Pages 87-91"},"PeriodicalIF":0.0,"publicationDate":"2006-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1053/j.sembd.2007.01.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57938925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Mobile Full-Field Digital Telemammography With Satellite Transmission of Images 卫星图像传输的移动全场数字遥测技术
Seminars in breast disease Pub Date : 2006-09-01 Epub Date: 2008-09-25 DOI: 10.1053/j.sembd.2007.01.003
Mary M. Kelly MD, Jay Parikh MD, FRCP(c), CPE, FSBI, FACPE, Kelly K. Shaw MPH, Paula S. Hallam MD
{"title":"Mobile Full-Field Digital Telemammography With Satellite Transmission of Images","authors":"Mary M. Kelly MD,&nbsp;Jay Parikh MD, FRCP(c), CPE, FSBI, FACPE,&nbsp;Kelly K. Shaw MPH,&nbsp;Paula S. Hallam MD","doi":"10.1053/j.sembd.2007.01.003","DOIUrl":"10.1053/j.sembd.2007.01.003","url":null,"abstract":"<div><p>Full-field digital mammography (FFDM) is a desirable technology for mobile screening programs. Satellite transmission of digital mammograms is fast, reliable, and secure. Digital telemammography with satellite transmission allows for on-line review of images and patient management. Performance of screening is at least as accurate with FFDM as with film screening. Our project has shown that implementation of FFDM with satellite transmission requires effort and resources but is feasible for the purpose of bringing state-of-the-art mammography to populations which are geographically remote, medically underserved, or busy in the workplace. We describe the implementation of a mobile screening FFDM program which transmits mammograms via satellite to a hospital-based breast center for image interpretation and patient management.</p></div>","PeriodicalId":87785,"journal":{"name":"Seminars in breast disease","volume":"9 3","pages":"Pages 92-98"},"PeriodicalIF":0.0,"publicationDate":"2006-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1053/j.sembd.2007.01.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57939115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Contrast-Enhanced Digital Mammography 对比增强数字乳房x线摄影
Seminars in breast disease Pub Date : 2006-09-01 Epub Date: 2008-09-25 DOI: 10.1053/j.sembd.2007.01.005
John Lewin MD
{"title":"Contrast-Enhanced Digital Mammography","authors":"John Lewin MD","doi":"10.1053/j.sembd.2007.01.005","DOIUrl":"10.1053/j.sembd.2007.01.005","url":null,"abstract":"<div><p>Contrast-enhanced digital mammography<span> has been proposed as a method for breast cancer detection and characterization. In this technique, an intravenous contrast agent is administered to increase the visibility of cancers on the mammographic image. Because breast cancers have been shown to enhance with contrast agents on both CT and MRI, it seems reasonable that contrast enhancement might work in mammography. Because the contrast resolution of mammography is less than that of CT or MRI, subtraction is used to increase the visibility of the enhancing cancer on the background of normal tissue. Two methods, temporal subtraction and dual-energy subtraction, have been proposed and demonstrated. Results from three pilot studies have been promising, with high sensitivity to cancer; however, much work remains before the technique becomes a viable clinical tool.</span></p></div>","PeriodicalId":87785,"journal":{"name":"Seminars in breast disease","volume":"9 3","pages":"Pages 105-110"},"PeriodicalIF":0.0,"publicationDate":"2006-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1053/j.sembd.2007.01.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57940346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Breast Tomosynthesis 乳房Tomosynthesis
Seminars in breast disease Pub Date : 2006-09-01 Epub Date: 2008-09-25 DOI: 10.1053/j.sembd.2007.02.009
Elizabeth A. Rafferty MD
{"title":"Breast Tomosynthesis","authors":"Elizabeth A. Rafferty MD","doi":"10.1053/j.sembd.2007.02.009","DOIUrl":"https://doi.org/10.1053/j.sembd.2007.02.009","url":null,"abstract":"<div><p>Mammographic screening has shown the ability to significantly reduce the mortality rate from breast cancer, but mammography does not detect all cancers. One of the major causes of decreased mammographic sensitivity is the structured noise that results from overlap of normal structures within the breast, which can obscure tumors, making them difficult to detect. Overlapping structures can also mimic abnormality and lead to false positive mammographic recalls. Tomosynthesis is a three-dimensional mammographic application that minimizes the impact of structured noise within the breast. Multiple low-dose projection images are taken on a mammographic platform and are then synthesized into a cross-sectional data set. Early clinical trials suggest that tomosynthesis has the potential to improve tumor visibility, more accurately identify tumor margins and decrease false positive mammographic callbacks that result from summation artifact.</p></div>","PeriodicalId":87785,"journal":{"name":"Seminars in breast disease","volume":"9 3","pages":"Pages 111-118"},"PeriodicalIF":0.0,"publicationDate":"2006-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1053/j.sembd.2007.02.009","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138344354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
IHE: What Is It and What Does It Have To Do with Mammography? he:它是什么?它与乳房x光检查有什么关系?
Seminars in breast disease Pub Date : 2006-06-01 Epub Date: 2008-09-25 DOI: 10.1053/j.sembd.2006.12.007
Margarita Zuley MD
{"title":"IHE: What Is It and What Does It Have To Do with Mammography?","authors":"Margarita Zuley MD","doi":"10.1053/j.sembd.2006.12.007","DOIUrl":"10.1053/j.sembd.2006.12.007","url":null,"abstract":"<div><p>As more and more breast imaging centers convert to full-field digital mammography, problems surrounding lack of system interoperability have come to light. Most medical facilities have a heterogeneous mix of different information systems that, if integrated properly, work together to provide practitioners with all the information necessary for patient care. In order for these systems to provide maximal operability and utility, the systems adhere to standards such as DICOM (Digital Imaging and Communications in Medicine) and HL7 (Health Level 7) as well as conform to integration profiles developed by IHE (Integrating the Healthcare Enterprise). This paper is intended to introduce the reader to IHE and specifically how the problems of integrating full-field digital mammography are being solved using IHE.</p></div>","PeriodicalId":87785,"journal":{"name":"Seminars in breast disease","volume":"9 2","pages":"Pages 82-84"},"PeriodicalIF":0.0,"publicationDate":"2006-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1053/j.sembd.2006.12.007","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57938899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Digital Mammography Integrated with PACS: Real World Issues, Considerations, Workflow Solutions, and Reading Paradigms 与PACS集成的数字乳房x线照相术:现实世界的问题、考虑、工作流程解决方案和阅读范例
Seminars in breast disease Pub Date : 2006-06-01 Epub Date: 2008-09-25 DOI: 10.1053/j.sembd.2006.12.006
Michael Trambert MD
{"title":"Digital Mammography Integrated with PACS: Real World Issues, Considerations, Workflow Solutions, and Reading Paradigms","authors":"Michael Trambert MD","doi":"10.1053/j.sembd.2006.12.006","DOIUrl":"10.1053/j.sembd.2006.12.006","url":null,"abstract":"<div><p>This article describes the 3.5 years experience of integrating digital mammography<span> with a generalized Picture Archiving Communications System (PACS). Rather than implement a mammography mini-PACS solution (dedicated solely for use in full-field digital mammography), the vision was to integrate full-field digital mammography with the preexisting PACS archive, network, and Web distribution system from the beginning. Our enterprise still utilized a separate proprietary mammography reading workstation, as required by the FDA at that time. The pros, cons, and lessons learned from this approach are presented. The enterprise is currently transitioning away from a separate mammography reading station. This transition will more fully integrate, using the overall PACS for mammography reporting, mammography tracking, document imaging module may be added in the future, management reporting, task tracking, and billing output with a single unified RIS/PACS solution. This paper describes the core technologies required for this approach, along with the theoretical advantages.</span></p></div>","PeriodicalId":87785,"journal":{"name":"Seminars in breast disease","volume":"9 2","pages":"Pages 75-81"},"PeriodicalIF":0.0,"publicationDate":"2006-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1053/j.sembd.2006.12.006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57938626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
Full-Field Digital Mammography: Introduction to Different Technologies 全视场数字乳房x线照相术:不同技术介绍
Seminars in breast disease Pub Date : 2006-06-01 Epub Date: 2008-09-25 DOI: 10.1053/j.sembd.2006.12.002
Elizabeth A. Rafferty MD
{"title":"Full-Field Digital Mammography: Introduction to Different Technologies","authors":"Elizabeth A. Rafferty MD","doi":"10.1053/j.sembd.2006.12.002","DOIUrl":"10.1053/j.sembd.2006.12.002","url":null,"abstract":"<div><p>Digital mammography separates the functions of image acquisition, display, and storage enabling each of them to be optimized. Although the spatial resolution of digital mammography is less than that of its analog counterpart, the markedly superior dynamic range provided by the digital platform may translate into improved cancer detection, particularly in dense breast tissue. Early clinical trials of digital mammography failed to confirm such a detection benefit; however, the Digital Mammographic Imaging Screening Trial, with its greater statistical power, did report increased sensitivity for the digital modality in young women, women who are pre- or peri-menopausal, and women with dense breast tissue. The true value of digital mammography, however, may lie in its ability to provide a platform on which advanced x-ray imaging applications for the breast may be developed. In this article, the different technologies of full-field digital mammography in current clinical practice are described.</p></div>","PeriodicalId":87785,"journal":{"name":"Seminars in breast disease","volume":"9 2","pages":"Pages 51-57"},"PeriodicalIF":0.0,"publicationDate":"2006-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1053/j.sembd.2006.12.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57938809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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