Update on cancer therapeutics最新文献_第7页

Abbreviations of drugs 药物简写

Update on cancer therapeutics Pub Date : 2007-06-01 DOI: 10.1016/S1872-115X(07)00038-2

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Copyright/Publication information 版权/发布信息

Update on cancer therapeutics Pub Date : 2007-06-01 DOI: 10.1016/S1872-115X(07)00037-0

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Abbreviations of chemotherapeutic combinations 化疗联合的缩写

Update on cancer therapeutics Pub Date : 2007-06-01 DOI: 10.1016/S1872-115X(07)00039-4

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Supportive care 支持性护理

Update on cancer therapeutics Pub Date : 2007-06-01 DOI: 10.1016/j.uct.2007.07.001

Maurie Markman

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Leukemias and plasma cell dyscrasias 白血病和浆细胞异常

Update on cancer therapeutics Pub Date : 2007-06-01 DOI: 10.1016/j.uct.2007.07.002

Peter H. Wiernik

{"title":"Leukemias and plasma cell dyscrasias","authors":"Peter H. Wiernik","doi":"10.1016/j.uct.2007.07.002","DOIUrl":"10.1016/j.uct.2007.07.002","url":null,"abstract":"<div>This review details major new observations in the diagnosis and treatment of leukemias and plasma cell dyscrasias that have been communicated since the last version of this work. This review is not exhaustive and may appear to some to be rather superficial. However, it should serve as an accurate index of current thinking and accomplishments. The review clearly demonstrates a trend away from traditional chemotherapeutic approaches to the leukemias and related diseases in favor of the more rational design of treatments for specific diseases based on laboratory observations. Some refer to the agents that have resulted from such an approach as targeted therapy and suggest that they represent a new era in cancer treatment, although one of the first targeted therapy agents to be conceived, synthesized and tested was 6-mercaptopurine decades ago. Furthermore, there is no cancer therapy more targeted than surgery, which has been practiced longer than any of us has lived. At any rate, whatever slogan may be used to describe current cancer treatment, it is clear that it is based on more preclinical science and more rational design than ever before. This chapter demonstrates that is certainly true for the leukemias and plasma cell dyscrasias. What has not been demonstrated yet is that better rationale has led to better results. That remains to be proven or disproven by continued observation of our treated patients.</div>","PeriodicalId":87487,"journal":{"name":"Update on cancer therapeutics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2007-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.uct.2007.07.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"55738460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Biological abbreviations 生物的缩写

Update on cancer therapeutics Pub Date : 2007-06-01 DOI: 10.1016/S1872-115X(07)00040-0

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NSC-numbers

Update on cancer therapeutics Pub Date : 2007-06-01 DOI: 10.1016/S1872-115X(07)00041-2

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Translational review of AIDS-related Kaposi's sarcoma 艾滋病相关卡波西肉瘤的研究进展

Update on cancer therapeutics Pub Date : 2007-03-01 DOI: 10.1016/j.uct.2007.04.002

Naveed Sarwar, Justin Stebbing, Mark Bower

{"title":"Translational review of AIDS-related Kaposi's sarcoma","authors":"Naveed Sarwar, Justin Stebbing, Mark Bower","doi":"10.1016/j.uct.2007.04.002","DOIUrl":"10.1016/j.uct.2007.04.002","url":null,"abstract":"<div>Approximately twice as many individuals are living with type 1 human immunodeficiency virus infection (HIV-1), as opposed to cancer and as such improved therapies for HIV-1 with an emphasis on availability of such medicines, is arguably the greatest medical problem of the 21st century. Importantly, these two conditions occur together and cancer remains a common cause of morbidity and mortality in the 60 million individuals infected with this retrovirus. In particular, there is a markedly increased risk of Kaposi's sarcoma, non-Hodgkin's lymphoma and invasive cervical cancer during the course of infection with this retrovirus. Treatment options are limited for patients with advanced acquired immunodeficiency syndrome related Kaposi sarcoma (AIDS-KS). The management of early stage cutaneous AIDS-KS has been revolutionised by the introduction of highly active anti-retroviral therapy (HAART) and for most patients HAART alone will control early stage AIDS-KS. However, patients with advanced stage KS with visceral disease, tumour-associated oedema or extensive oral disease require systemic chemotherapy in addition to their anti-retrovirals. Cytotoxic treatment is complicated however by underlying immunoparesis and options are often limited. Despite these difficulties, outcomes are improving and an increased appreciation of the biological mechanisms underlying viral tumorigenesis will hopefully delineate new therapeutic options and strategies.</div>","PeriodicalId":87487,"journal":{"name":"Update on cancer therapeutics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2007-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.uct.2007.04.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"55738439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Guide for authors 作者指南

Update on cancer therapeutics Pub Date : 2007-03-01 DOI: 10.1016/S1872-115X(07)00012-6

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Abbreviations of chemotherapeutic combinations 化疗联合的缩写

Update on cancer therapeutics Pub Date : 2007-03-01 DOI: 10.1016/S1872-115X(07)00009-6

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