{"title":"Integrating integrative medicine research: what can we learn from each other?","authors":"Shamini Jain, Paul J Mills","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":87409,"journal":{"name":"Journal of the Society for Integrative Oncology","volume":"6 2","pages":"45-6"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27490779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lyn Freeman, Lorenzo Cohen, Mary Stewart, Rebecca White, Judith Link, J Lynn Palmer, Derek Welton
{"title":"Imagery intervention for recovering breast cancer patients: clinical trial of safety and efficacy.","authors":"Lyn Freeman, Lorenzo Cohen, Mary Stewart, Rebecca White, Judith Link, J Lynn Palmer, Derek Welton","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In a phase I National Cancer Institute (NCI)-funded clinical trial, 34 breast cancer survivors, six weeks to one year post-treatment, were recruited to participate in a 6-class, 8-week long imagery stress reduction program entitled \"Envision the Rhythms of Life.\" Patients practiced imagery during and between sessions. Outcomes for quality of life and cortisol rhythm were assessed pre- to post-intervention, in two subsets of survivors (intravenous [IV] chemotherapy, or no IV chemotherapy). Thirty survivors completed the 8-week program. Quality of life outcomes demonstrated statistically and clinically significant outcomes for the functional assessment of cancer therapy-general (FACT-G) global index (p<.001), representing improvements in survivor quality of life related to physical, social/family, emotional, and function well-being. Survivors also improved significantly on the breast cancer (p<.001) and spiritual subscales (p = .008.) Brief symptom inventory (BSI) assessment reported significant improvement for the global index (p<.001) which included the categories of depression, somatization and anxiety. At eight weeks, cortisol rhythm, a biochemical indicator of stress and likelihood of cancer recurrence, produced a trend toward improvement for the fifth time point of the day (p = .18). Likert-based stress scales showed highly significant reductions in stress (p<.0001) with subjects practicing imagery the most producing the best scores. Outcomes suggest the imagery program may significantly improve survivor quality of life and reduce stress.</p>","PeriodicalId":87409,"journal":{"name":"Journal of the Society for Integrative Oncology","volume":"6 2","pages":"67-75"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27490782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Standish, C. A. Wenner, E. Sweet, C. Bridge, A. Nelson, M. Martzen, J. Novack, C. Torkelson
{"title":"Trametes versicolor mushroom immune therapy in breast cancer.","authors":"L. Standish, C. A. Wenner, E. Sweet, C. Bridge, A. Nelson, M. Martzen, J. Novack, C. Torkelson","doi":"10.2310/7200.2008.0016","DOIUrl":"https://doi.org/10.2310/7200.2008.0016","url":null,"abstract":"Data from multiple epidemiologic and clinical studies on immune effects of conventional cancer treatment and the clinical benefits of polysaccharide immune therapy suggest that immune function has a role in breast cancer prevention. Immune therapy utilizing the polysaccharide constituents of Trametes versicolor (Tv) as concurrent adjuvant cancer therapy may be warranted as part of a comprehensive cancer treatment and secondary prevention strategy.","PeriodicalId":87409,"journal":{"name":"Journal of the Society for Integrative Oncology","volume":"6 3 1","pages":"122-8"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2310/7200.2008.0016","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68604787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Standish, C. Torkelson, F. A. Hamill, D. Yim, A. Hill-Force, Annette L. Fitzpatrick, M. Olsen, S. Schildt, E. Sweet, C. A. Wenner, M. Martzen
{"title":"Immune defects in breast cancer patients after radiotherapy.","authors":"L. Standish, C. Torkelson, F. A. Hamill, D. Yim, A. Hill-Force, Annette L. Fitzpatrick, M. Olsen, S. Schildt, E. Sweet, C. A. Wenner, M. Martzen","doi":"10.2310/7200.2008.0018","DOIUrl":"https://doi.org/10.2310/7200.2008.0018","url":null,"abstract":"The purpose of this study was to evaluate the immune status of women with stage I-III breast cancer after receiving external beam radiotherapy (RT). Fourteen stage I-III, estrogen or progesterone receptor-positive or-negative (FER/PR +-), postsurgical breast cancer patients undergoing a standard course of chemotherapy and radiation were studied. Complete blood counts (CBC) with differential, phagocytic activity, natural killer (NK) cell functional activity, and tumor necrosis factor-alpha (TNF-alpha) and interferon-gamma cytokine activity were measured immediately before and for the six weeks following the completion of radiation therapy. Fatigue levels after completion of RT were measured using the Functional Assessment of Chronic Illness Therapy (FACIT)-Fatigue scale. Nonparametric statistical methods (Wilcoxon rank and Spearman correlations) were used to analyze the data. Compared with postchemotherapy, following the completion of RT, these breast cancer patients showed lymphopenia, low functional activity of natural killer lymphocytes, decreased monocyte phagocytic activity, and decreased TNF-alpha production but no neutropenia, no anemia, and no change in interferon-gamma production. Lymphocyte count did not return to normal by the end of the 6-week post-RT observation period. The severity of lymphopenia and low natural killer cell activity was related to RT area but not radiation dose. Patients did not report significant fatigue levels for the 6 weeks after completing RT. Significant decreases in the numbers and functions of cells from both the innate and adaptive immune system were detected following a standard course of radiation therapy for the treatment of breast cancer. Immune deficits in lymphocyte populations and TNF-alpha production, should they persist, may have consequences for immune response to residual or recurrent malignancy following completion of conventional treatment. The use of adjunctive immune therapies which target these specific defects may be warranted in the post-treatment period.","PeriodicalId":87409,"journal":{"name":"Journal of the Society for Integrative Oncology","volume":"6 3 1","pages":"110-21"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2310/7200.2008.0018","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68604794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Deng, B. Cassileth, L. Cohen, J. Gubili, P. Johnstone, Nagi B. Kumar, A. Vickers, D. Abrams, D. Rosenthal, S. Sagar, D. Tripathy
{"title":"Integrative Oncology Practice Guidelines.","authors":"G. Deng, B. Cassileth, L. Cohen, J. Gubili, P. Johnstone, Nagi B. Kumar, A. Vickers, D. Abrams, D. Rosenthal, S. Sagar, D. Tripathy","doi":"10.2310/7200.2007.002","DOIUrl":"https://doi.org/10.2310/7200.2007.002","url":null,"abstract":"Integrative Oncology Practice Guidelines Yuan-Sheng Liu, Jong-Hoon Lee, Yeon-Weol Lee, Chong-Kwan Cho, Hwa-Seung Yoo East-West Cancer Center, College of Oriental Medicine, Daejeon University The Society for Integrative Oncology (SIO) is an international organization established to encourage scientific evaluation, dissemination of evidence-based information, and appropriate clinical integration of complementary therapies (http://www.Integrativeonc.org.). Practice Guidelines were developed by the authors listed below and by the Executive Committee of the Society for Integrative Oncology, which approved this document. Guidelines are a work in progress; they will be updated as needed and are available on the SIO Web site as well: www.IntegrativeOnc.org.","PeriodicalId":87409,"journal":{"name":"Journal of the Society for Integrative Oncology","volume":"5 2 1","pages":"65-84"},"PeriodicalIF":0.0,"publicationDate":"2007-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68604391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Weidong Lu, David Hu, Elizabeth Dean-Clower, Anne Doherty-Gilman, Anna T R Legedza, Hang Lee, Ursula Matulonis, David S Rosenthal
{"title":"Acupuncture for chemotherapy-induced leukopenia: exploratory meta-analysis of randomized controlled trials.","authors":"Weidong Lu, David Hu, Elizabeth Dean-Clower, Anne Doherty-Gilman, Anna T R Legedza, Hang Lee, Ursula Matulonis, David S Rosenthal","doi":"10.2310/7200.2006.035","DOIUrl":"https://doi.org/10.2310/7200.2006.035","url":null,"abstract":"<p><p>Chemotherapy-induced leukopenia and neutropenia are common side effects during cancer treatment. Acupuncture has been reported as an adjunct therapy for this complication. The current study reviewed published randomized controlled trials of acupuncture's effect and explored the acupuncture parameters used in these trials. We searched biomedical databases in English and Chinese from 1979 to 2004. The study populations were cancer patients who were undergoing or had just completed chemotherapy or chemoradiotherapy, randomized to either acupuncture therapy or usual care. The methodologic quality of trials was assessed. From 33 reviewed articles, 682 patients from 11 eligible trials were included in analyses. All trials were published in non-PubMed journals from China. The methodologic quality of these trials was considerably poor. The median sample size of each comparison group was 45, and the median trial duration was 21 days. The frequency of acupuncture treatment was once a day, with a median of 16 sessions in each trial. In the seven trials in which white blood cell (WBC) counts were available, acupuncture use was associated with an increase in leukocytes in patients during chemotherapy or chemoradiotherapy, with a weighted mean difference of 1,221 WBC/muL on average (95% confidence interval 636-1,807; p < .0001). Acupuncture for chemotherapy-induced leukopenia is an intriguing clinical question. However, the inferior quality and publication bias present in these studies may lead to a false-positive estimation. Meta-analysis based on these published trials should be treated in an exploratory nature only.</p>","PeriodicalId":87409,"journal":{"name":"Journal of the Society for Integrative Oncology","volume":"5 1","pages":"1-10"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26561051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Training massage therapists to work in oncology.","authors":"Wendy Miner","doi":"10.2310/7200.2007.015","DOIUrl":"https://doi.org/10.2310/7200.2007.015","url":null,"abstract":"<p><p>Professional massage therapists (MTs) require specialized training to work safely and effectively with cancer patients and to prepare them for their role in multidisciplinary clinical settings. This article describes \"Medical Massage for the Cancer Patient,\" a certificate course offered to achieve those goals by the Integrative Medicine Service at Memorial Sloan-Kettering Cancer Center. MTs are taught the clinical, logistic, and legal requirements; the basic details of cancer and cancer treatments; necessary massage adaptations; and what will be required of them as members of a health care team. The core competencies this training program aims to impart, and the program developed to reach them, are outlined here. Specific training by a credible oncology team is required prior to any hands-on work with cancer patients.</p>","PeriodicalId":87409,"journal":{"name":"Journal of the Society for Integrative Oncology","volume":"5 4","pages":"163-6"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2310/7200.2007.015","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27904838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Echinacea purpurea.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":87409,"journal":{"name":"Journal of the Society for Integrative Oncology","volume":"5 4","pages":"167-8"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27904839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marie-Pierre Campeau, Réal Gaboriault, Martine Drapeau, Thu Van Nguyen, Isabelle Roy, Bernard Fortin, Mariette Marois, Phuc Félix Nguyen-Tân
{"title":"Impact of massage therapy on anxiety levels in patients undergoing radiation therapy: randomized controlled trial.","authors":"Marie-Pierre Campeau, Réal Gaboriault, Martine Drapeau, Thu Van Nguyen, Isabelle Roy, Bernard Fortin, Mariette Marois, Phuc Félix Nguyen-Tân","doi":"10.2310/7200.2007.018","DOIUrl":"10.2310/7200.2007.018","url":null,"abstract":"<p><p>Anxiety is a major issue in the cancer patient population. This randomized phase III trial evaluated the effects of massage therapy on anxiety levels in patients undergoing radiation therapy. Patients undergoing radiation therapy were randomly assigned to either 10 massage sessions or control sessions. Anxiety levels were evaluated throughout the course of treatment using both the visual analogue scale (VAS) and the State-Trait Anxiety Inventory (STAI). The immediate effect of massage therapy on anxiety scores was measured via pre- and postmassage VAS scores. The intermediate-term effect of massage was assessed through the VAS scores over the 10 sessions and STAI scores at the last session. The trial's primary outcome was the difference in intermediate-term anxiety scores, whereas the secondary outcome was the difference in immediate anxiety scores. Between January 2006 and June 2006, 100 patients were randomized. After their massage, the patients' immediate postmassage anxiety score according to the VAS was reduced by an average of 45% compared with their premassage score (p < .001). No impact of massage therapy on intermediate-term anxiety scores was observed. Both groups showed a similar decline in VAS anxiety scores from the first to the last session, that is, 15% and 19% in the massage therapy and control groups, respectively (p = .73). Furthermore, no difference was observed between the groups' respective state-anxiety scores after the 10 sessions. Massage therapy is associated with a significant, immediate decrease in anxiety scores. However, massage therapy appears to have no major impact on intermediate-term anxiety in patients undergoing radiation therapy.</p>","PeriodicalId":87409,"journal":{"name":"Journal of the Society for Integrative Oncology","volume":"5 4","pages":"133-8"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27904834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anita H Ambs, Melissa F Miller, Ashley W Smith, Michael S Goldstein, An-Fu Hsiao, Rachel Ballard-Barbash
{"title":"Religious and spiritual practices and identification among individuals living with cancer and other chronic disease.","authors":"Anita H Ambs, Melissa F Miller, Ashley W Smith, Michael S Goldstein, An-Fu Hsiao, Rachel Ballard-Barbash","doi":"10.2310/7200.2007.003","DOIUrl":"https://doi.org/10.2310/7200.2007.003","url":null,"abstract":"<p><p>Religion and spirituality in the context of health care are poorly understood, particularly for individuals with chronic illness. Using data from the 2003 Complementary and Alternative Medicine supplement to the 2001 California Health Interview Survey, we examined whether cancer survivors (n = 1,777) and individuals with other chronic illnesses (n = 4,784) were either more likely to identify themselves as religious and spiritual or more likely to use religious and spiritual practices for health purposes than individuals with no disease (n = 2,342). We observed that cancer survivors and individuals with chronic illnesses were more likely than those with no disease to use religious and spiritual prayer and healing practices. Individuals with chronic diseases were not inherently more likely to identify themselves as religious than were healthy individuals and were only slightly more likely to identify themselves as spiritual. These findings indicate that individuals with cancer and other chronic illnesses may be using religious and spiritual practices as a way to cope with their illness. Future research should continue to examine whether and how religious and spiritual practices are used as complementary or alternative medicine, and health care professionals should ask their patients about such use.</p>","PeriodicalId":87409,"journal":{"name":"Journal of the Society for Integrative Oncology","volume":"5 2","pages":"53-60"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26731350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}