{"title":"[Clinical significance of uremic toxin indoxyl sulfate and inflammation in the development of vascular calcification and cardiovascular complications in stage C3-C5D chronic kidney disease].","authors":"F U Dzgoeva, O V Remizov, V G Goloeva, Z R Ikoeva","doi":"10.26442/00403660.2023.06.202267","DOIUrl":"10.26442/00403660.2023.06.202267","url":null,"abstract":"<p><strong>Aim: </strong>To clarify the role of the uremic toxin indoxyl sulfate (IS) and inflammation in the development of vascular calcification and cardiovascular complications in chronic kidney disease (CKD).</p><p><strong>Materials and methods: </strong>One hundred fifteen patients aged 25 to 68 years with CKD stage C3-C5D were examined. Serum concentrations of IS, interleukin 6 (IL-6), tumor necrosis factor (TNF-α), troponin I, parathyroid hormone were determined by enzyme immunoassay using kits from BluGene biotech (Shanghai, China), Cloud-Clone Corp. (USA), ELISA Kit (Biomedica, Austria).</p><p><strong>Results: </strong>An increase in the serum concentration of IS, IL-6, TNF-α was revealed, which was significantly associated with a deterioration in renal function and changes in the morphological and functional parameters of the heart and aorta.</p><p><strong>Conclusion: </strong>High concentrations of IS, IL-6, TNF-α, which are closely associated with an increase in renal failure and cardiovascular complications, indicate their significant role in vascular calcification, which underlies the damage to the cardiovascular system in CKD.</p>","PeriodicalId":87408,"journal":{"name":"Journal of the Gay and Lesbian Medical Association","volume":"4 1","pages":"468-474"},"PeriodicalIF":0.3,"publicationDate":"2023-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79228765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Editorial: Transitions","authors":"V. Silenzio, J. Bradford","doi":"10.1023/A:1020336413909","DOIUrl":"https://doi.org/10.1023/A:1020336413909","url":null,"abstract":"","PeriodicalId":87408,"journal":{"name":"Journal of the Gay and Lesbian Medical Association","volume":"6 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2018-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/A:1020336413909","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46561293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marion H E Kavanaugh-Lynch, E. White, J. Daling, D. Bowen
{"title":"Correlates of Lesbian Sexual Orientation and the Risk of Breast Cancer","authors":"Marion H E Kavanaugh-Lynch, E. White, J. Daling, D. Bowen","doi":"10.1023/B:JOLA.0000011064.00219.71","DOIUrl":"https://doi.org/10.1023/B:JOLA.0000011064.00219.71","url":null,"abstract":"","PeriodicalId":87408,"journal":{"name":"Journal of the Gay and Lesbian Medical Association","volume":"6 1","pages":"91-95"},"PeriodicalIF":0.0,"publicationDate":"2002-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/B:JOLA.0000011064.00219.71","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57317898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Editorial: Same Sex, Different Health","authors":"V. Silenzio","doi":"10.1023/B:JOLA.0000011228.75703.09","DOIUrl":"https://doi.org/10.1023/B:JOLA.0000011228.75703.09","url":null,"abstract":"","PeriodicalId":87408,"journal":{"name":"Journal of the Gay and Lesbian Medical Association","volume":"3 1","pages":"89-90"},"PeriodicalIF":0.0,"publicationDate":"2002-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/B:JOLA.0000011228.75703.09","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57318140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Protection Against STDs, Hepatitis, and HIV/AIDS Includes Talking Openly and Honestly with Sex Partners and Medical Care Providers","authors":"K. Betts","doi":"10.1023/B:JOLA.0000011066.30850.EB","DOIUrl":"https://doi.org/10.1023/B:JOLA.0000011066.30850.EB","url":null,"abstract":"","PeriodicalId":87408,"journal":{"name":"Journal of the Gay and Lesbian Medical Association","volume":"6 1","pages":"111-115"},"PeriodicalIF":0.0,"publicationDate":"2002-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/B:JOLA.0000011066.30850.EB","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57317817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Major Mental Illness in a Sexual Minority Psychiatric Sample","authors":"R. Hellman, L. Sudderth, A. Avery","doi":"10.1023/B:JOLA.0000011065.08186.17","DOIUrl":"https://doi.org/10.1023/B:JOLA.0000011065.08186.17","url":null,"abstract":"","PeriodicalId":87408,"journal":{"name":"Journal of the Gay and Lesbian Medical Association","volume":"6 1","pages":"97-106"},"PeriodicalIF":0.0,"publicationDate":"2002-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/B:JOLA.0000011065.08186.17","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57317998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Original Research: Lesbian Health Education: A Survey of Obstetrics and Gynecology Residency Training Programs","authors":"P. Amato, D. Morton","doi":"10.1023/A:1021941405832","DOIUrl":"https://doi.org/10.1023/A:1021941405832","url":null,"abstract":"","PeriodicalId":87408,"journal":{"name":"Journal of the Gay and Lesbian Medical Association","volume":"6 1","pages":"47-51"},"PeriodicalIF":0.0,"publicationDate":"2002-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/A:1021941405832","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57211504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Special Article: Significant Risk Versus Acceptable Risk in Dental Treatment of HIV-Infected Individuals","authors":"A. W. Whitehead, John A. Hlaudy","doi":"10.1023/A:1021949707649","DOIUrl":"https://doi.org/10.1023/A:1021949707649","url":null,"abstract":"","PeriodicalId":87408,"journal":{"name":"Journal of the Gay and Lesbian Medical Association","volume":"6 1","pages":"75-78"},"PeriodicalIF":0.0,"publicationDate":"2002-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/A:1021949707649","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57211880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Horizons: Reflections on Interdisciplinary Work","authors":"A. Vega","doi":"10.1023/A:1021997523579","DOIUrl":"https://doi.org/10.1023/A:1021997523579","url":null,"abstract":"","PeriodicalId":87408,"journal":{"name":"Journal of the Gay and Lesbian Medical Association","volume":"6 1","pages":"71-73"},"PeriodicalIF":0.0,"publicationDate":"2002-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/A:1021997523579","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57216995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Original Research: How Did You Hear About the Study? Or, How to Reach Lesbian and Bisexual Women of Diverse Ages, Ethnicity, and Educational Attainment for Research Projects","authors":"E. Rothblum, Rhonda J. Factor, D. Aaron","doi":"10.1023/A:1021993422671","DOIUrl":"https://doi.org/10.1023/A:1021993422671","url":null,"abstract":"","PeriodicalId":87408,"journal":{"name":"Journal of the Gay and Lesbian Medical Association","volume":"6 1","pages":"53-59"},"PeriodicalIF":0.0,"publicationDate":"2002-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/A:1021993422671","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57216245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}