Research and reports in neonatology最新文献

{"title":"Hydrops fetalis: Incidence, Etiologies, Management Strategies, and Outcomes","authors":"Tamiko Younge, Katherine Ottolini, Huda Al-Kouatly, Seth Berger","doi":"10.2147/rrn.s411736","DOIUrl":"https://doi.org/10.2147/rrn.s411736","url":null,"abstract":"","PeriodicalId":87354,"journal":{"name":"Research and reports in neonatology","volume":"350 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139014887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Global Crisis of Congenital Syphilis: Vulnerable and Disenfranchised Women Most at Risk","authors":"Aoife Moore, Bridget Freyne, Clare Nourse","doi":"10.2147/rrn.s428322","DOIUrl":"https://doi.org/10.2147/rrn.s428322","url":null,"abstract":": Congenital syphilis (CS), previously considered by many paediatricians as a “historical disease”, has re-emerged as a significant preventable neonatal infection. While low-income countries have the highest burden of disease globally, notifications have increased in many high-income countries (HIC) in recent years. This literature report provides an overview of the current strategies for testing and treating syphilis in pregnancy (SIP) and CS and describes the changing global epidemiology of SIP. National SIP guidelines are reviewed with reference to testing in pregnancy and treatment of CS. The report highlights that there is an ongoing crisis of CS in HICs worldwide and a disproportionate burden is being experienced by vulnerable populations in these countries. Action is needed to address this crisis, and interventions aimed at overcoming social and structural barriers to antenatal care access for vulnerable populations should be prioritised.","PeriodicalId":87354,"journal":{"name":"Research and reports in neonatology","volume":"46 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138626730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neonatal Hydrometrocolpos Secondary to Imperforate Hymen Presented with Acute Urinary Retention: Case Report","authors":"Dereje Tegene, Tesfalem Assefa, Abdurahman Edris","doi":"10.2147/rrn.s433727","DOIUrl":"https://doi.org/10.2147/rrn.s433727","url":null,"abstract":"","PeriodicalId":87354,"journal":{"name":"Research and reports in neonatology","volume":"130 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135325901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Magnitude of Neonatal Admission Diagnosis and Associated Factors at Selected Hospitals in Wollo, Northeast Ethiopia","authors":"Shambel Asmamaw, Shiferaw Getachew, Tamrat Demeke, Hailu Hankarso, Birhan Alemnew, Shambel Wedajo, Asressie Molla","doi":"10.2147/rrn.s418964","DOIUrl":"https://doi.org/10.2147/rrn.s418964","url":null,"abstract":"Background: Neonates are commonly admitted to neonatal intensive care units, and the type(s) of admission determine the outcome of the neonate. Therefore, we sought to assess the magnitude of neonatal admission and associated factors at selected hospitals in Wollo, northeast Ethiopia in 2022. Methods: A cross-sectional study on 422 admitted mother–neonate pairs was conducted. Data were collected by face-to-face interviews and reviewing patient records and then entered and analyzed using EpiData version 3.1 and Stata version 14, respectively. Binary logistic regression analyses were employed, and P < 0.05 was considered statistically significant on multivariate analysis. Results: The prevalence of neonatal sepsis was 53.4% (95% CI 48.5%– 58.2%), low birth weight 36.9% (95% CI 32.3%– 41.7%), prematurity 24.2% (95% CI 20.3%– 28.5%), and hypoglycemia 9.7% (95% CI 7.2%– 13%). Urinary tract infection (AOR 2.22, 95% CI 1.13– 4.34), history of abortion (AOR 1.95, 95% CI 1.002– 3.78), and twin pregnancy (AOR 6.34, 95% CI 1.84– 11.83) were associated with low birth weight. Premature rupture of membrane (AOR 2.87 95% CI 1.31– 6.28), history of abortion (AOR 2.36, 95% CI 1.20– 4.61), and instrumental delivery (AOR 5.25, 95% CI 1.65– 16.71) were associated with neonatal sepsis. Male sex (AOR 2.78, 95% CI 1.45– 5.34), pregnancy-induced hypertension (AOR 2.73, 95% CI 1.13– 6.60), antepartum hemorrhage (AOR 3.24, 95% CI 1.03– 10.20), and premature rupture of membrane (AOR 2.77, 95% CI 1.23– 6.24) were associated with prematurity. Conclusion: The prevalence of low birth weight, prematurity, and neonatal sepsis was high, but neonatal hypoglycemia was low. Urinary tract infection, history of abortion, and twin pregnancy were associated with low birth weight. Premature rupture of membrane, history of abortion, and instrumental delivery were associated with neonatal sepsis. Male sex, pregnancy-induced hypertension, antepartum hemorrhage, and premature ruptures of membrane were associated with prematurity. Keywords: admission diagnosis, discriminant analysis, Ethiopia, neonatal admission, neonate","PeriodicalId":87354,"journal":{"name":"Research and reports in neonatology","volume":"66 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135515795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Updated Perspectives on the Diagnosis and Management of Neonatal Invasive Candidiasis","authors":"Katherine Daniel, Rachel G Greenberg, Angelique Boutzoukas, Lakshmi Katakam","doi":"10.2147/rrn.s409779","DOIUrl":"https://doi.org/10.2147/rrn.s409779","url":null,"abstract":"Abstract: Invasive candidiasis can cause severe illness in immunocompromised hosts, such as premature infants. Clinical presentation in neonates is variable and often characterized by non-specific signs with potential to involve several organ systems. Awareness of risk factors for Candida infections in the neonatal intensive care unit (NICU) can aid in screening infants with signs and symptoms of generalized illness. Cultures of blood, urine, and cerebrospinal fluid are the main diagnostic tools available in this population of infants, but several biomarkers and alternate identification methodologies such as 1,3-β-D-glucan, serum mannan or anti-mannan, and T2 magnetic resonance testing are being studied in the neonatal population. Prompt diagnosis of Candida infection, in conjunction with a comprehensive assessment of disease progression and organ involvement, is critical for optimizing treatment and patient outcomes. Supportive care and systemic antifungal medications remain the mainstay of treatment, and the efficacy and safety of newer therapeutic agents continue to be evaluated in neonates. Disease prevention strategies must be thoughtfully implemented and customized to each individual NICU based on local incidence of Candida infection, practice patterns, and risk factors, and may include prophylactic antifungal therapy. This review summarizes the evidence for current approaches to diagnosis and management of neonatal invasive candidiasis and provides an overview of the newer diagnostic tools and therapeutic agents on the horizon. Keywords: Candida , infant, biomarkers, amphotericin B, fluconazole, prophylaxis","PeriodicalId":87354,"journal":{"name":"Research and reports in neonatology","volume":"42 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135566508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antenatal Kratom Exposure: Literature Review and Clinical Management Recommendations","authors":"Alice Ordean","doi":"10.2147/rrn.s419864","DOIUrl":"https://doi.org/10.2147/rrn.s419864","url":null,"abstract":"","PeriodicalId":87354,"journal":{"name":"Research and reports in neonatology","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134935625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lived Experience of Mothers Having Preterm Newborns in a Neonatal Intensive Care Unit at Wolaita Sodo University Comprehensive Specialized Hospital Southern Ethiopia: A Phenomenological Study","authors":"Worku Mimani Minuta, Temesgen Lera Abiso, D. Haile, Abebe sorsa Badacho, Befekadu Bekele, Abera Gezume Ganta, Getachew Nigussie Bolado, Begidu Bashe","doi":"10.2147/rrn.s417173","DOIUrl":"https://doi.org/10.2147/rrn.s417173","url":null,"abstract":"","PeriodicalId":87354,"journal":{"name":"Research and reports in neonatology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46228045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Examining Practice Variation Used for Packed Red Blood Cell Transfusions for Preterm Infants in Neonatal Intensive Care Units Across the United States","authors":"Kayla C. Everhart, S. Donevant, V. Iskersky, M. Wirth, Robin B. Dail","doi":"10.2147/rrn.s379367","DOIUrl":"https://doi.org/10.2147/rrn.s379367","url":null,"abstract":"Purpose: Researchers report associations between packed red blood cell (PRBC) transfusions and morbid outcomes in preterm infants. Published standards are lacking for giving PRBC transfusions to preterm infants in the neonatal intensive care unit (NICU). This study examined standard practices reported by nurses across the United States (US) for administering PRBC transfusions to preterms to identify variation in practice which may contribute to the relationship of PRBC transfusions and morbidity. Design and Methods: A 23-item questionnaire developed using REDCap based on literature and nursing experience of experts on the procedure of administering PRBC transfusions to preterm infants was distributed via social media and email to NICU nurses across the US. Results: A total of 757 responses received and 518 completed responses were analyzed from level IV (48%) and level III (49%) NICU nurses in 47/50 US states. Most (94%) report PRBCs are ordered for anemia. Most (74%) report NICU policies do not specify warming PRBC transfusions prior to infusing; 10% (n = 53) specifically indicate they warm PRBC transfusions. Only 2% report using a blood warmer device. NICU nurses in the US (66%) reported feedings are altered during the PRBC transfusion. A 97% of nurses reported their NICU employs a specific physiologic assessment policy during PRBC transfusions. The two most common infusion sites used are (99%) peripheral IV as preferred and an umbilical venous catheter (74.5%) as next best option. Conclusion: This study reveals inconsistencies in PRBC transfusion practices in US NICUs. Vast inconsistencies were shown in warming transfusions and in feeding practices surrounding PRBC transfusions. Future research should examine these variations in PRBC transfusion practices for any contributions to the relationship of PRBC transfusions and morbidity in preterm infants. A standard guideline should be developed based on the research evidence to guide nurses in administering preterm PRBC transfusions.","PeriodicalId":87354,"journal":{"name":"Research and reports in neonatology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47297601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Saving the Lives of Asphyxiated Newborns in Public Health Facilities: An Implementation Research","authors":"Sanjay Shinde, Firew Tiruneh, Dinaol Abdissa","doi":"10.2147/rrn.s366328","DOIUrl":"https://doi.org/10.2147/rrn.s366328","url":null,"abstract":"Back Ground: Globally, 2.6 million children died in their first month of life—approximately 7 000 newborn deaths per day—with approximately one million dying on the first day and nearly one million dying within the next six days. Perinatal asphyxia plays a significant role in this mortality. Even those who survive will suffer from mental retardation and other complications. One programme to save the lives of asphyxiated newborns is “Helping Baby Breathe.” However, it has yet to be successful in Ethiopia. Objective: To assess the status of implementation of helping baby breath and to design alternative best way to improve the service, in public hospitals of Bench-Maji, Kaffa and Sheka zones. Methods: Concurrent triangulation was used in the design. We used a phenomenological and descriptive cross-sectional study design. The subjects of the study were key informants, postnatal mothers, and health care providers in the delivery ward. Atlas Ti and SPSS software were used to analyze qualitative and quantitative data, respectively. Results: We reported on the knowledge and skills of health care providers in neonatal resuscitation in this study. The findings revealed that participants with good knowledge and skill were 54% and 27%, respectively. A number of contextual factors that may be impeding neonatal resuscitation were also identified qualitatively. Conclusion: The majority of health care providers’ skill and knowledge of neonatal resuscitation were far below the minimum expected competency. mocking me, hahaha, who cares about the quality of a specific service?” Let me be bold and state that newborn resuscitation has never been on the agenda of a meeting. “We’re doing everything we can to assist baby breathe”, said the participant. According to specialists, however, the newborn may face challenges such as cold stress or illness. Due to the fact that these two elements are commonly disregarded. Our rash is designed to help us breathe and begin breathing.","PeriodicalId":87354,"journal":{"name":"Research and reports in neonatology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43502293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neonatal Sucking Blister and Sucking Pads: Coexisting Simultaneously in a 24 Hour Old Newborn","authors":"Gashaw Arega, Selamawit Daniel Admasse, Desalegn Alemneh","doi":"10.2147/rrn.s374095","DOIUrl":"https://doi.org/10.2147/rrn.s374095","url":null,"abstract":": Neonatal suckling blisters usually present as benign skin erosions involving the distal upper extremities at birth presumably induced by vigorous sucking in utero, whereas sucking pads commonly appear as hyperkeratotic thickening of the lips indicating effective neonatal sucking reflex. These benign neonatal conditions should be differentiated from other serious systemic and dermatological diseases in newborns through their clinical manifestations and self-limited course. Here, we report a 24 hour old male newborn with a sucking blister and sucking pads present at birth coexisting simultaneously, diagnosed based on the presentation and benign course. A high index of clinical suspicion is required to avoid unnecessary investigations and treatment.","PeriodicalId":87354,"journal":{"name":"Research and reports in neonatology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46705431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}