Kavya Mohankumar, Siddharth Karthikeya, Shaurya Mahajan, Jothsna Bodhanapati, Charles Vigilia, Mark Odron, Kenneth Blum, David Baron, Kai Uwe Lewandrowski, Rajendra D Badgaiyan, Edward J Modestino, Keerthy Sunder
{"title":"EEG-Spectra-Guided Personalized rTMS in PTSD with Co-occurring Psychiatric Disorders: A Case Series.","authors":"Kavya Mohankumar, Siddharth Karthikeya, Shaurya Mahajan, Jothsna Bodhanapati, Charles Vigilia, Mark Odron, Kenneth Blum, David Baron, Kai Uwe Lewandrowski, Rajendra D Badgaiyan, Edward J Modestino, Keerthy Sunder","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Personalized repetitive Transcranial Magnetic Stimulation (PrTMS<sup>®</sup>) offers an individualized approach to neuromodulation through customized treatment protocols. This case series aims to explore therapeutic outcomes of PrTMS<sup>®</sup> in two patients with post-traumatic stress disorder (PTSD), based on standardized rating scale scores and spectral EEG-guided alpha brainwave activity optimization. Participants diagnosed with PTSD received PrTMS<sup>®</sup> treatments informed by quantitative rating scales and weekly spectral EEG measurements. Weekly psychometric assessments showed an improvement in symptoms, as quantified by PCL-5 (Posttraumatic Stress Disorder Checklist for DSM-5), GAD-7 (Generalized Anxiety Disorder 7-item scale), PHQ-9 (Patient Health Questionnaire-9), and SCI (Sleep Condition Indicator) questionnaires. Specifically, PCL-5 scores demonstrated an average reduction of 20.5 points by the midpoint of treatment (4 weeks), while GAD-7 and PHQ-9 scores decreased by 7 and 8.5 points, respectively, at the end of 7 weeks. Mean SCI scores increased by 6 points by the end of the 7 week-treatment period. While previous studies have also highlighted the role of spectral EEG-directed personalized PrTMS in the treatment of PTSD, ongoing research is needed in order to understand the long-term efficacy of PrTMS<sup>®</sup>.</p>","PeriodicalId":87216,"journal":{"name":"Acta scientific neurology","volume":"8 2","pages":"3-9"},"PeriodicalIF":0.0,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11931688/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stan Pierce, Kenneth Blum, Kai-Uwe Lewandrowski, Igor Elman, Deborah Zelinsky, Alireza Sharafshah, Aryeh R Pollack, Rajendra D Badgaiyan
{"title":"EPIC Technique Spinal Procedure Improves Ocular Motion and Dizziness by Resolving Cranial Nerve VI Palsy.","authors":"Stan Pierce, Kenneth Blum, Kai-Uwe Lewandrowski, Igor Elman, Deborah Zelinsky, Alireza Sharafshah, Aryeh R Pollack, Rajendra D Badgaiyan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This case study demonstrates that craniocervical spinal alignment with the EPIC technique spinal procedure appears to have a potential positive impact on ocular function. This paper will report the case of a patient with cranial nerve VI palsy and dizziness, and the clinical improvements following treatment with the soundwave technology of the EPIC technique spinal procedure [1].</p><p><strong>Objective: </strong>To report the case of a patient with cranial nerve VI (CN VI) palsy and the clinical changes that occurred after receiving treatment using the EPIC (Evolutionary Percussion Instrument Corrections) technique spinal procedure.</p><p><strong>Clinical presentation and evaluation: </strong>A 52-year-old female presented with acute insidious onset of cranial nerve VI palsy with complaints of headache and feelings of increased head pressure. Upon eye movement exam, left eye abduction was absent which additionally caused double vision. A neurovascular physical examination using the EPIC technique protocols revealed evidence of the presence of craniocervical subluxation.</p><p><strong>Radiographic findings: </strong>A four-view pre-adjustment digital radiographic series of the craniocervical region was taken and analyzed utilizing the EPIC technique protocols. The patient's epigenetic structural profile (aka. epigenetic profile) was ascertained as well as the multidimensional vertebral malalignments between occiput (C0), atlas (C1), axis (C2), and angle of lower neck deviation (aka. misalignment profile).The C1 vertebra was laterally displaced to the right in a -θZ direction, and rotationally displaced in a +θY direction. C2 was rotationally displaced in a -θY direction (aka. \"spinous left\") with a lower neck deviated to the left in a +θZ direction. It is important to note the opposite rotational displacement of C1 and C2 about the Y axis, referred to as counter-rotational malpositions of C1/C2 [1] also referred to as a \"variable subluxation\" [2].Numerous epigenetic variations were present, the most important of which was bilateral elongated styloid processes observed down to the level of C1 transverse processes.A single correction vector was then calculated based on both the epigenetic and misalignment profiles of data. [1].</p><p><strong>Intervention and outcomes: </strong>The patient was given a single soundwave impulse treatment (correction) to her craniocervical region according to the EPIC technique protocols of care using the Integrity Genesis adjusting instrument [1]. Immediately following the initial correction, the patient was re-evaluated for the presence of subluxation using the EPIC neurovascular physical exam and radiographic assessments. Findings revealed neurovascular indicators of subluxation were no longer present. A two-view post-adjustment EPIC digital radiographic series was taken to measure the biomechanical/structural changes from the treatment. Post-adjustment analysis revealed 95% reduction of C1 laterality (θZ), 22","PeriodicalId":87216,"journal":{"name":"Acta scientific neurology","volume":"7 7","pages":"3-10"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11615893/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142782114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lívio Pereira de Macêdo, Marcos Alcino Soares Siqueira Marques-Júnior, Ítalo Emmanuel Lima Ferreira, Renata Raizza Monterazzo-Cysneiros, Ubiratan Alves Viturino da Silva, Marcos Antonio Barbosa Da Silva, Bruno Anderson Araújo da Mota, José Laercio Júnior-Silva, Carlos Gustavo Coutinho Abath
{"title":"Two Basilar Fenestration Aneurysms Management - Image in Neurosurgery","authors":"Lívio Pereira de Macêdo, Marcos Alcino Soares Siqueira Marques-Júnior, Ítalo Emmanuel Lima Ferreira, Renata Raizza Monterazzo-Cysneiros, Ubiratan Alves Viturino da Silva, Marcos Antonio Barbosa Da Silva, Bruno Anderson Araújo da Mota, José Laercio Júnior-Silva, Carlos Gustavo Coutinho Abath","doi":"10.31080/asne.2024.07.0744","DOIUrl":"https://doi.org/10.31080/asne.2024.07.0744","url":null,"abstract":"","PeriodicalId":87216,"journal":{"name":"Acta scientific neurology","volume":"265 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141402070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Meshal Jarebi, C. Capel, Pierre-Henri Launois, Michel Lefranc, Johann Peltier
{"title":"Overcoming Adversity: Triumph in Managing Recurrent Grade 1 Parasagittal Meningioma Metastasized to the Lung with Surgical Precision and Radiosurgical Resolution. Case Report","authors":"Meshal Jarebi, C. Capel, Pierre-Henri Launois, Michel Lefranc, Johann Peltier","doi":"10.31080/asne.2024.07.0746","DOIUrl":"https://doi.org/10.31080/asne.2024.07.0746","url":null,"abstract":"","PeriodicalId":87216,"journal":{"name":"Acta scientific neurology","volume":"19 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141407725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Charisse Litchman, Caroline Stowe, Larry Rubin, Joseph DiTrapani, Sharon Stoll
{"title":"Potential Therapeutic Benefits of Using the BeCare MS Link App Frequently","authors":"Charisse Litchman, Caroline Stowe, Larry Rubin, Joseph DiTrapani, Sharon Stoll","doi":"10.31080/asne.2024.07.0738","DOIUrl":"https://doi.org/10.31080/asne.2024.07.0738","url":null,"abstract":"","PeriodicalId":87216,"journal":{"name":"Acta scientific neurology","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141389811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Construction and Validation of a New BrainView qEEG Discriminant Database","authors":"Annie TL Young, S. Danev, Jonathan RT Lakey","doi":"10.31080/asne.2024.07.0742","DOIUrl":"https://doi.org/10.31080/asne.2024.07.0742","url":null,"abstract":"","PeriodicalId":87216,"journal":{"name":"Acta scientific neurology","volume":"33 13","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141404042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}