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Timely topics in medicine. Cardiovascular diseases最新文献

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Plasma NT-proBNP: a new biomarker for diagnosis and monitoring of congestive heart failure (CHF). 血浆NT-proBNP:诊断和监测充血性心力衰竭(CHF)的新生物标志物
Timely topics in medicine. Cardiovascular diseases Pub Date : 2006-04-01
Antoni Bayes-Genis
{"title":"Plasma NT-proBNP: a new biomarker for diagnosis and monitoring of congestive heart failure (CHF).","authors":"Antoni Bayes-Genis","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":87159,"journal":{"name":"Timely topics in medicine. Cardiovascular diseases","volume":"10 ","pages":"E10"},"PeriodicalIF":0.0,"publicationDate":"2006-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26330625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fabry disease. Fabry疾病。
Timely topics in medicine. Cardiovascular diseases Pub Date : 2006-04-01
Mark Levin
{"title":"Fabry disease.","authors":"Mark Levin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Fabry disease is an inherited enzyme deficiency of galactosidase A that results in various phenotypes: classic, cardiac or renal. It can present variably and may represent an important cause of occult neurological and cardiac syndromes and renal failure. Preclinical and clinical studies demonstrate effectiveness of enzyme infusion in controlling and preventing these manifestations of the disease.</p>","PeriodicalId":87159,"journal":{"name":"Timely topics in medicine. Cardiovascular diseases","volume":"10 ","pages":"E8"},"PeriodicalIF":0.0,"publicationDate":"2006-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26330626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cerebrovascular disease and dementia. 脑血管疾病和痴呆。
Timely topics in medicine. Cardiovascular diseases Pub Date : 2006-04-01
Velandai Srikanth, Michael M Saling, Amanda G Thrift, Geoffrey A Donnan
{"title":"Cerebrovascular disease and dementia.","authors":"Velandai Srikanth,&nbsp;Michael M Saling,&nbsp;Amanda G Thrift,&nbsp;Geoffrey A Donnan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Cerebrovascular disease and dementia are extremely prevalent and disabling disorders affecting older people. Results of previous pathological investigations and later epidemiological studies have raised the possibility that the two disorders may be causally related. The study of such causal associations may provide insights that could lead to the development of strategies intended to prevent or treat dementia more effectively. Cerebrovascular disease has many manifestations, some of which are strong causal factors in the development of a future dementia. However, uncertainty and controversy exist regarding the presence and nature of the causal contribution of others. Potential therapeutic strategies for dementia are hindered by the lack of understanding of such relationships and the consequent difficulty in identifying a clear phenotype of dementia occurring predominantly due to cerebrovascular disease. The field is ripe for further examination of the associations between vascular factors and dementia, and the mechanisms underlying such associations. The interface between basic and clinical science has much to offer in clarifying the relationships between aging, vascular factors and cognitive decline in older people. In this review, we will attempt to synthesize data available from epidemiological, clinical and basic science research in the field of dementia related to cerebrovascular disease, highlighting potential avenues for further research.</p>","PeriodicalId":87159,"journal":{"name":"Timely topics in medicine. Cardiovascular diseases","volume":"10 ","pages":"E9"},"PeriodicalIF":0.0,"publicationDate":"2006-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26330627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of chronic infection and inflammation in the pathogenesis of cardiovascular and cerebrovascular disease. 慢性感染和炎症在心脑血管疾病发病机制中的作用。
Timely topics in medicine. Cardiovascular diseases Pub Date : 2006-03-01
Marina Diomedi, Giorgia Leone, Antonio Renna
{"title":"The role of chronic infection and inflammation in the pathogenesis of cardiovascular and cerebrovascular disease.","authors":"Marina Diomedi,&nbsp;Giorgia Leone,&nbsp;Antonio Renna","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Molecular and cellular immune activities have a fundamental role in all stages of the atherosclerotic process and in the pathogenesis of cerebrovascular and cardiovascular diseases. Recent studies have demonstrated how chronic infections can support a local and systemic chronic inflammation, leading to the atherosclerotic process. The pathogenic link between infection and cardiovascular and cerebrovascular disease is not completely defined. Some therapeutic strategies, able to influence the persistence of the infections or to modify the inflammatory process, could be useful in primary and secondary vascular disease prevention and in modifying the acute event outcome.</p>","PeriodicalId":87159,"journal":{"name":"Timely topics in medicine. Cardiovascular diseases","volume":"10 ","pages":"E6"},"PeriodicalIF":0.0,"publicationDate":"2006-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25895444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vascular medicine in Australia and Germany: highlights from the First International Conference in Vascular Medicine, held August 26-28, 2005, in Melbourne, Australia. 澳大利亚和德国的血管医学:2005年8月26-28日在澳大利亚墨尔本举行的第一届国际血管医学会议的亮点。
Timely topics in medicine. Cardiovascular diseases Pub Date : 2006-03-01
Sheila A Doggrell
{"title":"Vascular medicine in Australia and Germany: highlights from the First International Conference in Vascular Medicine, held August 26-28, 2005, in Melbourne, Australia.","authors":"Sheila A Doggrell","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Recent developments highlighted from the First International Conference in Vascular Medicine, held in Melbourne, Australia, August 26-28, 2005, are in nitric oxide signaling, oxidative stress, homeostasis, the angiotensin-aldosterone system, diabetes, new vessel formation and P-selectin.</p>","PeriodicalId":87159,"journal":{"name":"Timely topics in medicine. Cardiovascular diseases","volume":"10 ","pages":"E7"},"PeriodicalIF":0.0,"publicationDate":"2006-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25895445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inflammation, the key to much pathology. Highlights from the 7th World Congress on Inflammation, held August 20-24, 2005, in Melbourne, Australia. 炎症是许多病理学的关键。2005年8月20日至24日在澳大利亚墨尔本举行的第七届世界炎症大会的亮点。
Timely topics in medicine. Cardiovascular diseases Pub Date : 2006-02-01
Sheila A Doggrell
{"title":"Inflammation, the key to much pathology. Highlights from the 7th World Congress on Inflammation, held August 20-24, 2005, in Melbourne, Australia.","authors":"Sheila A Doggrell","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>From the World Congress on Inflammation, held August 20-24, 2005 in Melbourne, Australia, new targets and new drugs for inflammation of the respiratory system (asthma, allergic rhinitis, chronic obstructive pulmonary disease and cystic fibrosis), inflammatory bowel disease (ulcerative colitis and Crohn's disease), arthritis (rheumatoid and osteoarthritis), atherosclerosis and cancer are discussed.</p>","PeriodicalId":87159,"journal":{"name":"Timely topics in medicine. Cardiovascular diseases","volume":"10 ","pages":"E4"},"PeriodicalIF":0.0,"publicationDate":"2006-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25854224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cardiac regeneration and repair: do they really exist? 心脏再生和修复:它们真的存在吗?
Timely topics in medicine. Cardiovascular diseases Pub Date : 2006-02-01
John Martin
{"title":"Cardiac regeneration and repair: do they really exist?","authors":"John Martin","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":87159,"journal":{"name":"Timely topics in medicine. Cardiovascular diseases","volume":"10 ","pages":"E5"},"PeriodicalIF":0.0,"publicationDate":"2006-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25854226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Serotonergic mechanisms: a potential link between affective disorders and cardiovascular risk. 血清素能机制:情感性障碍与心血管风险之间的潜在联系。
Timely topics in medicine. Cardiovascular diseases Pub Date : 2006-02-01
Ginés Escolar, Maribel Díaz-Ricart, Esther Gomez-Gil, Montserrat Serra, Cristobal Gasto, Jordi Bozzo, Ana Maria Galán
{"title":"Serotonergic mechanisms: a potential link between affective disorders and cardiovascular risk.","authors":"Ginés Escolar,&nbsp;Maribel Díaz-Ricart,&nbsp;Esther Gomez-Gil,&nbsp;Montserrat Serra,&nbsp;Cristobal Gasto,&nbsp;Jordi Bozzo,&nbsp;Ana Maria Galán","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Cardiovascular disease and major depression are highly prevalent disorders in our society. Evidence has been found that confirms a reciprocal relationship between mechanisms of depression and those of cardiovascular pathology. This possible feedback between both pathologies is a subject of great concern. In recent years some studies suggest that platelets and serotonergic mechanisms could be involved in both conditions. The present review seeks a better understanding of the mechanisms that could link depression with an enhanced cardiovascular risk.</p>","PeriodicalId":87159,"journal":{"name":"Timely topics in medicine. Cardiovascular diseases","volume":"10 ","pages":"E3"},"PeriodicalIF":0.0,"publicationDate":"2006-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25854223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Leptin as a common link to obesity and hypertension. 瘦素是肥胖和高血压的常见诱因。
Timely topics in medicine. Cardiovascular diseases Pub Date : 2006-01-02
Ratnakar Mukherjee, Daniel Villarreal, Garry P Reams, Ronald H Freeman, Inna Tchoukina, Robert M Spear
{"title":"Leptin as a common link to obesity and hypertension.","authors":"Ratnakar Mukherjee,&nbsp;Daniel Villarreal,&nbsp;Garry P Reams,&nbsp;Ronald H Freeman,&nbsp;Inna Tchoukina,&nbsp;Robert M Spear","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Leptin is a recently isolated circulating peptide hormone that is primarily synthesized and secreted by adipocytes. One of the major functions of this hormone is the control of energy balance by binding to receptors in the hypothalamus, leading to reduction in food intake, elevation in temperature and energy expenditure. In addition, increasing evidence suggests that leptin, through both direct and indirect actions, may play an important role in cardiovascular and renal functions. While the relevance of endogenous leptin needs further clarification, it appears to be a potential pressure- and volume-regulating factor, and may function pathophysiologically as a common link to obesity and hypertension.</p>","PeriodicalId":87159,"journal":{"name":"Timely topics in medicine. Cardiovascular diseases","volume":"10 ","pages":"E1"},"PeriodicalIF":0.0,"publicationDate":"2006-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25793709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antibiotic therapy for coronary heart disease: the myth and the reality. 抗生素治疗冠心病:神话与现实。
Timely topics in medicine. Cardiovascular diseases Pub Date : 2006-01-02
V C Kuppuswamy, S Gupta
{"title":"Antibiotic therapy for coronary heart disease: the myth and the reality.","authors":"V C Kuppuswamy,&nbsp;S Gupta","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Atherosclerosis is acknowledged as an active inflammatory and thrombotic disease, as opposed to simple degeneration. Infection with microorganisms may contribute to this inflammation and hence the atherosclerotic process. The \"infective\" hypothesis - first proposed more than a century ago by Virchow - has been revisited in recent years and has implicated numerous microorganisms as potential stimuli. The greatest body of evidence points to Chlamydia pneumoniae, a respiratory pathogen, as the \"culprit\" microorganism. Consistent finding of bacterial antigens, DNA and occasionally live \"viable\" organisms within human atherosclerotic plaque support the evidence for the concept linking C. pneumoniae to atherosclerosis. Although original seroepidemiological studies indicated an association, more recent prospective and larger studies suggest that there may be only a weak link between elevated antibodies and immune complexes to C. pneumoniae and coronary heart disease (CHD). Animal models have shown how atherogenesis can be induced by endovascular infection with C. pneumoniae; in vitro studies have explored various immunological and inflammatory pathways linking infection and atherothrombosis. On the basis of this, antibiotic trials have been explored to assess whether there is any role for antichlamydial agents in the treatment of cardiovascular events. Here, we focus on the main antibiotic studies and explores patient criteria and choice, duration of therapy, and whether effects on clinical events could be reduced.</p>","PeriodicalId":87159,"journal":{"name":"Timely topics in medicine. Cardiovascular diseases","volume":"10 ","pages":"E2"},"PeriodicalIF":0.0,"publicationDate":"2006-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25793710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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